2,058 research outputs found

    Microbial cell factories for the sustainable manufacturing of B vitamins

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    Vitamins are essential compounds in human and animal diets. Their demand is increasing globally in food, feed, cosmetics, chemical and pharmaceutical industries. Most current production methods are unsustainable because they use non-renewable sources and often generate hazardous waste. Many microorganisms produce vitamins naturally, but their corresponding metabolic pathways are tightly regulated since vitamins are needed only in catalytic amounts. Metabolic engineering is accelerating the development of microbial cell factories for vitamins that could compete with chemical methods that have been optimized over decades, but scientific hurdles remain. Additional technological and regulatory issues need to be overcome for innovative bioprocesses to reach the market. Here, we review the current state of development and challenges for fermentative processes for the B vitamin group

    Skyrmion-skyrmion and skyrmion-edge repulsions in skyrmion-based racetrack memory

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    Magnetic skyrmions are promising for building next-generation magnetic memories and spintronic devices due to their stability, small size and the extremely low currents needed to move them. In particular, skyrmion-based racetrack memory is attractive for information technology, where skyrmions are used to store information as data bits instead of traditional domain walls. Here we numerically demonstrate the impacts of skyrmion-skyrmion and skyrmion-edge repulsions on the feasibility of skyrmion-based racetrack memory. The reliable and practicable spacing between consecutive skyrmionic bits on the racetrack as well as the ability to adjust it are investigated. Clogging of skyrmionic bits is found at the end of the racetrack, leading to the reduction of skyrmion size. Further, we demonstrate an effective and simple method to avoid the clogging of skyrmionic bits, which ensures the elimination of skyrmionic bits beyond the reading element. Our results give guidance for the design and development of future skyrmion-based racetrack memory

    Musikstädte as real and imaginary soundscapes: urban musical images as literary motifs in twentieth-century German modernism

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    PhDThis study examines German literary images of musical life as part of the wider sound identity of the modern German city at the turn of the twentieth century. Focussing on a forty-year period from 1890 to 1930, synonymous with the emergence of the modern German metropolis as an aesthetic object, the project assesses, compares and contrasts how musical life in the Musikstädte was perceived and portrayed by writers in an increasingly noisy urban environment. How does urban musical life influence and condition city writings? What are the differences and similarities between the writings on various musical cities? Can an urban textual sound identity be derived from these differences and similarities? The approach employed to answer these questions is a new, cross-disciplinary one to urban sound in literature, moving beyond reading the key sounds of the urban soundscape using urban musicology, sensorial anthropology and cultural poetics towards a literary contextualisation of the urban aural experience. The literary motifs of the symphony, the gramophone and urban noise are put under the spotlight through the analysis of a wide range of modernist works by authors who have a special relationship with music. At the centre of this analysis are the Kaffeehausliteratur authors Hermann Bahr, Alfred Polgar and Peter Altenberg, the then Munich-based author Thomas Mann and the lesser known René Schickele. The analysis of these particular works is framed in the music-geographical context of the Musikstadt and literary underpinnings of this topos, ranging from Ingeborg Bachmann to Hans Mayer and, once again, Thomas Mann. In analysing these texts, the methodological approach devised by Strohm, who identifies the blending of a range of urban sounds as a definition of urban space and identity, is applied. His ideas combine historical literary analysis, musical history and urban sociology. They are rarely used in the analysis of the auditory environment.Arts and Humanities Research Council Westfield TrustWestfield Trust Studentship Arts and Humanities Reseach Council (AHRC

    Author Correction: Applying federated learning to combat food fraud in food supply chains

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    “In this article the affiliation details for Anand Gavai, Yamine Bouzembrak, Hans J. P. Marvin were incorrectly given as ‘Anand Gavai1, Yamine Bouzembrak2, Hans J. P. Marvin9 ‘, but should have been ‘Anand Gavai1,2, Yamine Bouzembrak2,3, Hans J. P. Marvin2,9’. The original article has been corrected.”</p

    Il coraggio del realismo: Hans J. Morgenthau e Reinhold Niebuhr

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    During the twentieth century, two seminal thinkers of the Political realism, Reinhold Niebuhr and Hans J. Morgenthau, contrasted with the prevailing approach of the contemporary social sciences, denouncing the alleged abuses of positivism, the problematic relationship between science and values, and the weak boundary between description and prescription. On one hand, the Protestant theologian studied the domestic and international politics of the United States, opposing to liberal idealism and stating an anti-Pelagian stance. On the other hand, the author of Politics Among Nations reflected on the «poverty» of scientism applied to the study of politics and highlighted the «limits» of power. Both scholars agreed with the need not only to exceed the rationalism that united the political science but also to use realism in order to better understand politics. At the same time, they reaffirmed the inextricable ethical and normative dimension of the political action. This article analyzes their contribution in order to expose its potentials as well as limits

    Genre, science, and ‘Hans Pfaall'

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    This essay moves beyond questions of source study and reception to show how “The Unparalleled Adventure of One Hans Pfaall” mixes genres of satire and realism. In doing so, Poe not only participates in the early development of science fiction but also explores emerging relationships between scientific and literary discourses during the nineteenth-century print revolution, which made it difficult to distinguish between fictions and facts. “Hans Pfaall” selfconsciously dramatizes through stylistic turbulence how knowledge is generically produced within unruly media ecologies and is thus epistemologically unstable. In this sense, the story— not in spite but precisely because of its generic and aesthetic inconsistencies—can be regarded less as an unsuccessful hoax and more as a narrative about the dynamics of writing and reading fiction under conditions of doubt.First author draf

    Social Motives and Their Development in Cultural Context

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    This paper deals with differences in social motives between cultures and with respect to their development. First, social motives are described as complex functional systems. Then aggressiveness and achievement motivation are dealt with as examples. Assumptions about biological factors are discussed and cultural differences are reported. Based on cross-cultural research, variations in early mother-child relations and in cultural norms and values are discussed as main sources of individual and cultural differences

    Övningsbok i lantbruksekonomi

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    Övningsboken i lantbruksekonomi innehåller räkneuppgifter och tentamensfrågor med lösningsförslag som använts i undervisning mellan 2001–2023 i kurser med professor emeritus Hans Andersson vid Sveriges lantbruksuniversitet. Boken har initierats på förslag av universitetsadjunkt Lovisa Nilsson, institutionen för ekonomi samt agronom Magnus J Stark, SLU Kompetenscentrum företagsledning. Målet med övningsboken är att åstadkomma kunskapshöjning inom lantbrukets företagsledning i syfte att stärka konkurrenskraften för Sveriges primärproducenter. Detta genom att utgöra ett stöd för studenter vid agrara utbildningar, lärare, intresserade lantbruksföretagare, rådgivare och kursledare. Boken är uppdelad i tematiska avsnitt som tillsammans täcker en stor del av de företagsekonomiska utmaningar som lantbruksföretagare står inför, och bygger på årtionden av forskning och utveckling av ämnesområdet lantbruksekonomi

    Syntax of Dutch: Adpositions and Adpositional Phrases

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    The volume Adpositions and Adpositional Phrases discusses the internal make-up and the distribution of adpositional phrases. Topics that are covered include complementation and modification of adpositional phrases, as well as their predicative, attributive and adverbial uses. A separate chapter is devoted to the formation and the syntactic behavior of pronominal PPs like erop ‘on it’, which also includes a more general discussion of the syntax of so-called R-words like er ‘there’

    Intertextual Episodes in Lectures: A Classification from the Perspective of Incidental Learning from Reading

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    In a parallel language environment it is important that teaching takes account of both the languages students are expected to work in. Lectures in the mother tongue need to offer access to textbooks in English and encouragement to read. This paper describes a preliminary study for an investigation of the extent to which they actually do so. A corpus of lectures in English for mainly L1 English students (from BASE and MICASE) was examined for the types of reference to reading which occur, classifi ed by their potential usefulness for access and encouragement. Such references were called ‘intertextual episodes’. Seven preliminary categories of intertextual episode were identifi ed. In some disciplines the text is the topic of the lecture rather than a medium for information on the topic, and this category was not pursued further. In the remaining six the text was a medium for information about the topic. Three of them involved management, of texts by the lecturer her/himself, of student writing, or of student reading. The remaining three involved reference to the content of the text either introducing it to students, reporting its content, or, really the most interesting category, relativizing it and thus potentially encouraging critical reading. Straightforward reporting that certain content was in the text at a certain point was the most common type, followed by management of student reading. Relativization was relatively infrequent. The exercise has provided us with categories which can be used for an experimental phase where the effect of different types of reference can be tested, and for observation of the references actually used in L1 lectures in a parallel-language environment
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