202,203 research outputs found
Violation of a Leggett-Garg inequality with ideal non-invasive measurements
No full textThe quantum superposition principle states that an entity can exist in two different states simultaneously, counter to our 'classical' intuition. Is it possible to understand a given system's behaviour without such a concept? A test designed by Leggett and Garg can rule out this possibility. The test, originally intended for macroscopic objects, has been implemented in various systems. However to date no experiment has employed the 'ideal negative result' measurements that are required for the most robust test. Here we introduce a general protocol for these special measurements using an ancillary system, which acts as a local measuring device but which need not be perfectly prepared. We report an experimental realization using spin-bearing phosphorus impurities in silicon. The results demonstrate the necessity of a non-classical picture for this class of microscopic system. Our procedure can be applied to systems of any size, whether individually controlled or in a spatial ensemble.</p
Characterization of the APEX2-GARG-1060 proximity biotinylation system.
No full textA. Domain organization of GBF1 and the C-terminally truncated GBF1 constructs fused to EGFP (positive control) and APEX2. Both GBF1 truncated constructs contain the BFA-resistant Sec7 domain from ARNO. B. Polio replicon replication was assessed in the presence or absence of 2μg/ml of BFA in HeLa cells transfected with plasmids expressing the C-terminally truncated GBF1 fusions with APEX2 or EGFP, or an empty vector C. Polio replicon replication assay was performed in control HeLa cells, or HeLa cells stably expressing APEX2-GARG-1060 with or without 2μg/ml of BFA. D. HeLa cells stably expressing APEX2-GARG-1060 were infected (or mock-infected) with 10 PFU/cell of poliovirus, and the biotinylation reaction was performed at 4 h p.i. The cells were processed for visualization of biotinylated proteins with a fluorescent streptavidin conjugate and immunostaining for a poliovirus antigen 3A. E. HeLa cells stably expressing APEX2-GARG-1060 were infected (or mock-infected) with poliovirus and the biotinylation reaction was performed as in D. The cells were stained with a fluorescent streptavidin conjugate and antibodies against a poliovirus antigen 2B and processed for structural illumination superresolution (SIM) microscopy. The arrow shows biotinylation-positive structures identified as stress granules. The scale bar is 10μm. F. HeLa cells stably expressing APEX2-GARG-1060 were infected (PV), or mock-infected (M) with 10 PFU/cell of poliovirus, and protein biotinylation was assessed after performing the biotinylation reaction at 4 h p.i. with biotin-phenol (BP) and hydrogen peroxide (complete reaction), or without one, or both compounds.</p
Comment on 'A scattering quantum circuit for measuring Bell's time inequality:a nuclear magnetic resonance demonstration using maximally mixed states'
No full textA recent paper by Souza, Oliveira and Sarthour (SOS) reports the experimental violation of a Leggett-Garg (LG) inequality (sometimes referred to as a temporal Bell inequality). The inequality tests for quantum mechanical superposition: if the inequality is violated, the dynamics cannot be explained by a large class of classical theories under the heading of macrorealism. Experimental tests of the LG inequality are beset by the difficulty of carrying out the necessary so-called 'non-invasive' measurements (which for the macrorealist will extract information from a system of interest without disturbing it). SOS argue that they nevertheless achieve this difficult goal by putting the system in a maximally mixed state. The system then allegedly undergoes no perturbation during their experiment. Unfortunately, the method is ultimately unconvincing to a skeptical macrorealist and so the conclusions drawn by SOS are unjustified.</p
Biotinylation of viral proteins by APEX2-GARG-1060.
No full textA. Poliovirus genome and polyprotein processing scheme. The cleavage sites for the viral proteases 2A, 3C, and 3CD are indicated by green, red, and blue-filled triangles, respectively. The dashed empty green triangle indicates a 2A cleavage site in 3D believed to be dispensable for replication. The purple star indicates the autocatalytic cleavage site in VP0. B. HeLa cells stably expressing APEX2-GARG-1060 were infected (PV), or mock-infected (M) with 10 PFU/cell of poliovirus, and biotinylation reactions were performed at the indicated times post-infection. Unfractionated cellular lysates (input) and isolated biotinylated proteins were analyzed in a Western blot with indicated antibodies. The antibodies recognize the final and intermediate polyprotein cleavage products containing the corresponding antigen. Red stars on anti-3A and anti-3D panels indicate polyprotein fragments that do not match the known polyprotein cleavage products.</p
Garg PhD Thesis Metabolic Modeling Calculations
No full textThis fits the metabolic model developed by Mehdi Alemi and Alan Asbeck to the raw data from Garg 1976 PhD Thesis, p. 198 and beyond (raw data tables).Citation for Garg 1976:GARG, Arun, 1947- A METABOLIC RATE PREDICTION MODEL FOR MANUAL MATERIALS HANDLING JOBS. The University of Michigan, Ph.D., 1976 Engineering, industrial.</div
Textbook of Operative Dentistry / Nisha Garg and Amit Garg.
No full textdental bookfair2016xiv, 524 p.
Quantified Data Automata on Skinny Trees: an Abstract Domain for Lists
No full textAbstract. We propose a new approach to heap analysis through an ab-stract domain of automata, called automatic shapes. Automatic shapes are modeled after a particular version of quantified data automata on skinny trees (QSDAs), that allows to define universally quantified prop-erties of programs manipulating acyclic heaps with a single pointer field, including data-structures such singly-linked lists. To ensure convergence of the abstract fixed-point computation, we introduce a subclass of QSDAs called elastic QSDAs, which forms an abstract domain. We eval-uate our approach on several list manipulating programs and we show that the proposed domain is powerful enough to prove a large class of these programs correct.
Leggett-Garg Macrorealism and temporal correlations
No full textLeggett and Garg formulated macrorealist models encoding our intuition on
classical systems, i.e., physical quantities have a definite value that can be
measured with minimal disturbance, and with the goal of testing macroscopic
quantum coherence effects. The associated inequalities, involving the
statistics of sequential measurements on the system, are violated by quantum
mechanical predictions and experimental observations. Such tests, however, are
subject to loopholes: a classical explanation can be recovered assuming
specific models of measurement disturbance. We review recent theoretical and
experimental progress in characterizing macrorealist and quantum temporal
correlations, and in closing loopholes associated with Leggett-Garg tests.
Finally, we review recent definitions of nonclassical temporal correlations,
which go beyond macrorealist models by relaxing the assumption on the
measurement disturbance, and their applications in sequential quantum
information processing.Comment: 22 pages, 7 figures. Final versio
Revised Strain Index – RSI (Garg, Moore, & Kapellusch, 2017)
No full textTexto de apoio.[Excerto] Introdução: Em postos de trabalho com um predomínio de trabalho manual e de esforços repetitivos, os trabalhadores estão continuamente expostos ao risco de desenvolvimento de Lesões Musculoesqueléticas Relacionadas com o Trabalho (LMERT) das Extremidades Distais dos membros Superiores (EDS). Estas lesões podem afetar os
cotovelos, antebraços, punhos e mãos, sendo frequentemente reportadas em trabalhadores de escritório (com uso contínuo de computador), como noutros contextos ocupacionais onde se verifique uma contínua realização
de tarefas manuais repetitivas (Garg & Kapellusch, 2011). A síndrome do túnel cárpico é a LMERT-EDS mais comum em contextos industriais de manufatura (Garg et al., 2012), sendo o Revised Strain Index (RSI) um método focado na previsão de ocorrência de lesões em músculos e tendões do punho (especialmente para a referida síndrome) (Roman-Liu, 2014). É de destacar que os autores do método salientam que este foi desenhado para
determinar o risco de LMERT-EDS associado a um dado posto de trabalho, e não para avaliar pessoas (Garg et al., 2017).
Para além de fatores organizacionais, ambientais e pessoais, os principais fatores de risco que levam ao desenvolvimento deste tipo de lesões são: força manual, frequência de movimentos, posturas incorretas, duração
da tarefa com movimentos repetitivos. Na literatura científica existem vários métodos observacionais que permitem avaliar quantitativamente o risco de ocorrência destas lesões, incluindo o RSI que considera os fatores
anteriormente mencionados. Este método, considerando a sua versão original, é recomendado pela ISO 11228-3:2007 para a uma avaliação analítica do risco de LMERT-EDS (Antonucci, 2019). Recentemente, Garg et al. (2017) apresentaram o RSI como uma versão revista do Strain Index (SI), inicialmente proposto por Moore & Garg (1995). [...
Sampling hurdles : “Borderline Illegitimate” to legitimate data.
No full textIn this paper the author discusses how sampling access and recruitment problems encountered in an in-depth interview study heightened her sensitivity to “borderline illegitimate” data. The term illegitimate data usually refers to the data collected during a covert study, whereas “legitimate” data are collected during an overt study. Hence, data collected during any nonconsented period(s) of an overt study lie on the borderline of illegitimacy and legitimacy, and constitute what the author calls borderline illegitimate data. Such data need legitimization before use. The borderline illegitimate data were collected during the pre- and postinterview stages of her study as they explained how medical and ethnic cultures and sensitivity to racism as a topic combined to create sample recruitment difficulties of the study. The author later legitimized them by sharing them with the participants, guaranteeing anonymity, and asking their permission to use them
- …
