1,720,961 research outputs found

    Imaging and depression in multiple sclerosis: a historical perspective

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    Patients affected with multiple sclerosis suffer from depression more frequently than the general population. Beyond psychosocial, genetic and immune-inflammatory factors, also the brain damage which is peculiar of multiple sclerosis has been claimed to have a role in the aetiology of depression in those patients. The study of this interesting relation has been implemented with both conventional and advanced magnetic resonance imaging techniques. The aim of this review is to provide a historical perspective on the link between multiple sclerosis-related depression and structural and functional brain damage

    The Meeting Center Support Programme (MCSP), a combined support programme for people with dementia (PWD) and their caregivers: first results in Italy after 7 months of attendance

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    Objectives: The MEETINGDEM Project aims to implement an innovative approach to support people with mild-moderate dementia (PWD) and their families in Italy, Poland and UK. This person-centered approach (Meeting Center Support Programme -MCSP-) has already been implemented in the Netherlands and demonstrated benefits (reduced behavioural and mood problems -BPSD-, delayed admission to residential care, higher levels of carer competence and lower levels of burden). MCSP proposes activities to stimulate PWD, support for caregivers (CGS) and actions for both. Our aim is to investigate differences between PWD and CGS partipating in two Italian Centers (Milano Zona 4 , Milano Zona 7; N=26+26) and an Italian control group (CTR -usual care- N=10+10). Materials and Methods: PWD were recruited according to the Global Deterioration Scale score (GDS: 4-5). Dyads of both groups were assessed at the beginning of participation in the project (T0) and after 7 months (T1) to collect data about behavioural disturbances and distress level through NeuroPsychiatric Inventory (NPI) administration. Results: At first T0-T1 design was applied (ANCOVA repeated measures 2x2, taking into account the baseline data and potential confounders as covariates). Our preliminary results are from NPI data: CGS Δ distress is statistically different in MCSP vs CTR group (p=0.002; covariates: Center, age, education years, cohabitation); Δ BPSD gravity (FxG) (p=0.034; covariates: Center, age, education years). Applying multiple regression to a four-factor model of NPI about CGS Δ distress we find that in MCSP group ‘Behavioural’ (p=0.015) and ‘Euphoria’ (p=0.019) factors can predict the distress pattern whereas in CTR group only ‘Behavioural’ factor (p=0.022) can predict it. Discussion: Significant differences were found in perceived distress by caregivers: these first preliminary data support the efficacy of the MCSP approach to sustain caregivers of PWD. A significant difference was also found regarding FxG of BPSD. This finding is in agreement with previous studies demonstrating the efficacy of multidimensional approaches to reduce BPSD. Conclusion: We present preliminary results about BPSD of PWD and caregiver distress. These results suggest that dementia impact on quality of life of caregivers could be decreased and BPSD could be reduced by combining support for PWD and their carers

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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