79 research outputs found
Arctic teacher education and educator training: a postcolonial review of online approaches and practices
No full textDigitalisation, and expanding digital infrastructure has given rise to new pedagogical approaches and practises that involve making use of the internet. In the development of this literature-based article, we examined Arctic online education from a holistic perspective, adopting broad definitions of online learning environments and teacher education. The aim of this paper is to map and analyse the state of knowledge regarding the digital transformations of practices and conceptualisations in teacher education and educator training in the Arctic, as we sought to answer the following research question: What is Arctic in online teaching and learning in teacher education and educator training? Our methodology consisted of a scoping review of peer-reviewed papers published between 2003-2023. Through a qualitative content analysis, we explored definitions, perspectives and positions that emanated from the literature. Viewed through the lens of postcolonial theory, our findings and discussion surface important points of ‘difference’ (Verran, 2013) between Indigenous pedagogies, which are a central part of the Arctic-ness, and technological advances that enable online and distance learning, namely: Rootedness And Fluidity; Continuity of the Story And Fragmentation; Preservation And Transformation; Traditional Seeing And (Western) Frameworks, which we argue should be a key feature of conversations within this field
A case study of contextual factors which influence the implementation of a model bilingual program
No full textThe political landscape of No Child Left Behind Act (NCLB) created a sense of urgency about the performance of the growing population of English learners. As a result, emerging studies examined the characteristics of principals’ and teachers’ practices in exemplary schools and model programs for English learners. However, no studies have examined the larger contextual framework which impacts these model programs for English learners. This dissertation study identified contextual factors that influenced the implementation of a model transitional bilingual program through the lenses of various stakeholders at all levels of one educational community. From the national perspective to the socio-cultural features and responses at the district level, to the background experiences and practices of the school leaders, this case study, completed over a twelve month period, triangulated data through interviews, observations and documents. A conceptual framework guided the initial data analysis followed with the identification of emerging patterns. The data indicated three major factors which shaped the implementation of a model bilingual program: political landscape, the district instructional leadership which shaped the principals’ interactions. First, the standards movement and accountability measures of the NCLB Act (2002) surfaced as a major catalyst at all levels. This legislation motivated this district to align standards, instruction and assessment to improve outcomes while pressuring principals to focus on test results (Honig, Copland, Rainey, Lorton & Newton, 2010; Johnson & Chrispeels, 2010). Accordingly, relational and structural organizations emerged as key factors in supporting the teaching and learning process (Johnson & Chrispeels, 2010). As district supervisors aligned the curriculum for all learners and provided consistent professional development, a knowledgeable bilingual director designed and supervised the district-wide bilingual program. Expert bilingual staff integrated initiatives throughout the system while maintaining the philosophical integrity of the bilingual program (Darling-Hammond et al., 2005; Griego-Jones, 1995). Finally, the principals’ cultural responsiveness and collaborative leadership styles influenced their interactions with school and community members (Carranza, 2010; Murphy, Elliott, Goldring & Porter, 2006). In summary, all district and school level administrators assumed responsibility for specific features of the bilingual program while all bilingual personnel expanded their responsibilities to implement district-wide initiatives.Ed. D.Includes bibliographical referencesby Elizabeth Jane Frank
Miniature literary marketplaces: Conceptions of authorship in Mary Elizabeth Braddon’s fiction
No full textDrawing together Braddon’s writing and the rapidly evolving Victorian literary world, this thesis examines the remarkable number of fictional authors in Mary Elizabeth Braddon’s novels. Miniature literary marketplaces are found in the pages of The Doctor’s Wife, The Lady’s Mile, Birds of Prey, Charlotte’s Inheritance, Dead-Sea Fruit, Hostages to Fortune, Vixen, One Thing Needful, His Darling Sin, and The Infidel, an array of novels stretching across Braddon’s exceptional career. The first chapter traces Braddon’s life and literary career as she negotiated between capitalising on her (in)famous status as queen of sensation fiction and influentially participating in contemporary literary fashions. The second chapter explores the practicalities of the literary profession illustrated in Braddon’s novels. Braddon unflinchingly acknowledges the marriages, households, and collaborations intertwined with professional authorship. Serialisation was integral to the Victorian literary profession and chapter three hones in on Dead-Sea Fruit’s serialisation in Belgravia; I examine Braddon as author and editor strategically confronting her position as target for fears surrounding the commodification of literature and anxieties about the place of women writers in the Victorian literary sphere. The final chapter makes the unlikely pairing of Mary Elizabeth Braddon and Sarah Grand, and their metafictional novels The Infidel and The Beth Book. Despite their differences, these women writers used their fictional writers to consciously enter contemporary conversations on female authorship. The project examines how Braddon’s metafiction depicts not only her experience as a writer but her understanding of the multifarious Victorian literary marketplace, love of literature, and commitment to forging a commercially successful career. Braddon’s conflicting desires and contentious place in the periodical press are echoed in her selfconscious and often confrontational representations of authorship. This thesis explores these fascinating fictional writers as a window into Braddon’s career and the Victorian literary marketplace
Professional Materials
No full textLiterature-Based Social Studies: Children\u27s Books and Activities to Enrich the K-5 Curriculum. Mildred Knight Laughlin and Patricia Payne Kardaleff. 1991. Children\u27s Books: Aldo Peanut Butter. Johanna Hurwitz. 1990; Alison\u27s Zinnia. Anita Lobel, author and illustrator. 1991;Building a House. Byron Barton. 1990; Manatee on Location. Kathy Darling. 1991; Yellow Ball. Molly Bang. 1991; By The Sea. Michelle Koch. 1991; The Twelve Days of Summer. Elizabeth L. O\u27Donnell. 1991. Reviewed By: Sherry Myers, Linda K. Judy, Cindy Overly, and Jeanne M. Jacobso
MiR-145 expression accelerates esophageal adenocarcinoma progression by enhancing cell invasion and anoikis resistance.
No full textBACKGROUND: Carcinoma of the esophagus has a high case fatality ratio and is now the 6th most common cause of cancer deaths in the world. We previously conducted a study to profile the expression of miRNAs in esophageal adenocarcinoma (EAC) pre and post induction therapy. Of the miRNAs differentially expressed post induction chemoradiation, miR-145, a known tumor suppressor miRNA, was upregulated 8-fold following induction therapy, however, its expression was associated with shorter disease-free survival. This unexpected result was explored in this current study. METHODS: In order to study the role of miR-145 in EAC, miRNA-145 was overexpressed in 3 EAC cell lines (OE33, FLO-1, SK-GT-4) and one ESCC cell line (KYSE-410). After validation of the expression of miR-145, hallmarks of cancer such as cell proliferation, resistance to chemotherapy drugs or anoikis, and cell invasion were analyzed. RESULTS: There were no differences in cell proliferation and 5 FU resistance between miR145 cell lines and the control cell lines. miR-145 expression also had no effect on cisplatin resistance in two of three cell lines (OE33 and FLO-1), but miR-145 appeared to protect SK-GT-4 cells against cisplatin treatment. However, there was a significant difference in cell invasion, cell adhesion and resistance to anoikis. All three EAC miR-145 cell lines invaded more than their respective controls. Similarly, OE33 and SK-GT-4 miR-145 cell lines were able to survive longer in a suspension state. DISCUSSION: While expression of miR-145 in ESCC stopped proliferation and invasion, expression of miR-145 in EAC cells enhanced invasion and anoikis resistance. Although more work is required to understand how miR-145 conveys these effects, expression of miR-145 appears to promote EAC progression by enhancing invasion and protection against anoikis, which could in turn facilitate distant metastasis
Darling, Flora Adams (25 July 1840–06 January 1910), author and founder of women's patriotic societies
No full textThe intimacy which is knowledge : female friendship in the novels of women writers
No full textThe thesis offers a historical account of the
representation of friendship in the novels of English
women writers from the nineteenth century to the
present. Questioning the prevalent understanding of the
history of women's friendship in terms of a single major
rupture, from nineteenth-century 'innocence' to
twentieth-century 'guilt', the thesis identifies
narrative configurations which recur throughout this,
period, and which define friendship as a formative
learning experience integrally related to the
acquisition of gendered identity. It concludes that
there can be no final and 'perfect' representation of
friendship, since the nature of the "knowledge' shared
has continually shifted in relation to changing
understandings of femininity.
Chapter 1 identifies the origins and nature of the
Victorian concept of the "second self", in which the
friend acts as the mirror of, and means of access to, an
idealised female subjectivity. Chapter 2 analyses the
ways in which this concept informs the narrative
patterns and rituals in Victorian fictions of
friendship. Chapter 3 offers a new reading of novels by
Elizabeth Gaskell, George Eliot and Charlotte Bronte, in
which the conventions identified in Chapter 2 are
adapted to question the existing boundaries of feminine
identity. Chapter 4 examines the impact of changes in
women's education upon the representation of friendship
in turn-of-the-century feminist and anti-feminist
novels, and in a new genre, the school story for girls.
Chapter 5 shows that the scientific construct of
lesbianism produced a new distinction between the
'healthy' and the 'unhealthy' relationship, but that the
terms of this distinction were contested; in
twentieth-century novels of the 'gyriaeceum', the
tradition continues, but is newly eroticised. Chapter 6
looks at friendship as 'revision' in recent English and
American novels, in which earlier configurations are
redeployed in the light of contemporary feminist concern
to recuperate and re-imagine the past
A Multi-factor Analysis of the Emergence of a Specialist-based Economy among the Phoenix Basin Hohokam
No full textabstract: This project examines the social and economic factors that contributed to the development of a specialist-based economy among the Phoenix Basin Hohokam. In the Hohokam case, widespread dependence on the products of a few concentrated pottery producers developed in the absence of political centralization or hierarchical social arrangements. The factors that promoted intensified pottery production, therefore, are the keys to addressing how economic systems can expand in small-scale and middle-range societies. This dissertation constructs a multi-factor model that explores changes to the organization of decorated pottery production during a substantial portion of the pre-Classic period (AD 700 - AD 1020). The analysis is designed to examine simultaneously several variables that may have encouraged demand for ceramic vessels made by specialists. This study evaluates the role of four factors in the development of supply and demand for specialist produced red-on-buff pottery in Hohokam settlements. The factors include 1) agricultural intensification in the form of irrigation agriculture, 2) increases in population density, 3) ritual or social obligations that require the production of particular craft items, and 4) reduced transport costs. Supply and demand for specialist-produced pottery is estimated through a sourcing analysis of non-local pottery at 13 Phoenix Basin settlements. Through a series of statistical analyses, the study measures changes in the influence of each factor on demand for specialist-produced pottery through four temporal phases of the Hohokam pre-Classic period. The analysis results indicate that specialized red-on-buff production was initially spurred by demand for light-colored, shiny, decorated pottery, but then by comparative advantages to specialized production in particular areas of the Phoenix Basin. Specialists concentrated on the Snaketown canal system were able to generate light-colored, mica-dense wares that Phoenix Basin consumers desired while lowering transport costs in the distribution of red-on-buff pottery. The circulation of decorated wares was accompanied by the production of plainware pottery in other areas of the Phoenix Basin. Economic growth in the region was based on complementary and coordinated economic activities between the Salt and the Gila River valleys.Dissertation/ThesisPh.D. Anthropology 201
Identity and consumption practices of Northamptonshire Caribbeans c.1955-1989
No full textThe objective of this thesis is to delineate and analyse Northamptonshire Caribbeans' consumption c.1955-1989. Author-collected and other oral histories alongside complementary primary and secondary references dovetail to unearth and analyse aspects of Post-War Caribbean consumption in a British provincial location that have been significantly unexplored previously. Central to the argument is the contention that identity is fundamentally significant in comprehending and analysing Northamptonshire Caribbeans' consumption. Various conceptualisations of identity facilitated development of consumer materialisations and aspirations. This thesis explores how multiple forms of identity as Caribbean, Black and British people were significant in shaping local Caribbeans' consumption. The succeeding pages address and analyse how these multiple identities influenced consumption and how provincial consumer behaviour was shaped by Caribbeans' relative co-ethnic isolation in Northamptonshire. Chapter 3 delineates and analyses consumer practices and practicalities of Northamptonshire Caribbeans. Integral within these consumer practices and practicalities are changes in consumption over time, intergenerational differences in consumption, as well as aspects of consumption that could be considered 'typical' and/or 'atypical' Northamptonshire Caribbean consumption; all of which are incorporated within this chapter. Chapter 4 connects identity and consumption through enhancing understanding of Northamptonshire Caribbeans' consumer networks. These networks interacted with the combination of identities local Caribbeans psychologically felt part of within various Caribbean, Black and British permutations. Furthermore, such identities varied more widely amongst the younger generation than their co-ethnic elders, a concept which is also addressed. Education and cultural currency are two novel strands through which to analyse connections between consumption and identity. The final two chapters deploy these concepts in an innovative manner creating and developing greater understanding of Northamptonshire Caribbeans' consumption. Chapter 5 expounds on the concept that education can be used as consumption whilst shaping future consumer behaviour, both ideas significantly under-explored previously. Chapter 6 introduces the theory of cultural currency, the idea that aspects of culture have finite, but changing, values and must be shared to have value similar to monetary currencies having exchange values for other monetary currencies. This chapter demonstrates how Northamptonshire Caribbeans shared aspects of Caribbean culture as cultural currency, fostering co-ethnic strength whilst gaining inter-ethnic respect for Caribbeans. Through comprehending Caribbean identity, correlations between empirical and social history, local consumption, as well as educational and cultural circumstances that stimulated and inspired Northamptonshire Caribbeans, this thesis distinctively illuminates how local Caribbeans' consumption interacted with various permutations of Afro-Caribbean, Black and/or British identities whilst representing idiosyncratic local nodes within these larger amalgamations
MiR-145 inhibited cell proliferation, delayed wound closure and enhanced anoikis in ESCC cells.
No full text<p>(A) Cell proliferation and (B) wound healing assay of KYSE-410 pcmv and KYSE-410 miR-145 cells. miR-145 expression in KYSE-410 led to decreased numbers of colonies after cell suspension culture (C) and enhanced PARP and caspase 3 cleavage (D).*: p<0.05, n = 3.</p
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