264 research outputs found
Endocarditi infettive e patologia del cavo orale
No full textIntroduction. The Infective Endocarditis is a rare disease of the endocardium and subendocardium. If untreated it is always fatal. Prophylaxis guidelines that have been published since the 1950s, always focused on dental procedures as a source of bacteremia causing Infective Endocarditis, rather than on daily activities like tooth brushing or chewing food.
Aim of the study. To assess if the state of oral health in patients with Infective Endocarditis may be considered a predisposing factor for developing Infective Endocarditis; to analyse underlying cardiac conditions associated with the risk to develop Infective Endocarditis and if presence of comorbid factors such as diabetes mellitus, immunosuppression and dialysis may increase the risk of adverse outcome from Infective Endocarditis in these patients. To define when Infective Endocarditis prophylaxis is or is not recommended for dental procedures.
Material and Methods. We enrolled two patients groups: Group Cases 1 from the Unit of Cardiovascular Pathology database, Hospital of Padova (177 patients), Group Cases 2 from the Unit of Infective and Tropical Diseases database, Hospital of Padova (70 patients). For each patient medical records were taken in order to analyse the presence of underlying cardiac conditions, stratified according to the American Heart Association classification 1997, and to review radiographic material useful for the state of health of the oral cavity.
Three Control Groups were identified: the Control Group 1, constituted by healthy patients (70 patients), the Control Group 2 constituted by patients with not infective cardiovascular diseases (50 patients), the Control Group 3 constituted by patients with comorbid conditions.
Group Cases 2 and Control Groups were separately analyzed with Chi Square test with 95% Confidence; Odd Ratio, Sensibility and Specificity tests, Positive and Negative Likelihood Ratio.
Results. In Group Cases 1 and 2, Aortic Valve is the most affected site (57.9%), followed by Mitral Valve (31.2%) and both Aortic and Mitral Valve (4.4%).
The most frequent underlying cardiac conditions were: bicuspid aortic valve (11.9%), aortic bioprosthesis (11.9%) and “floppy” mitral valve (10.7%) in Group Cases 1; aortic valve bioprosthesis (11.4%), non-rheumatic aortic valve stenosis (8.6%) and bicuspid aortic valve (5.7%) in Group Cases 2.
In Group Cases 1 death occurred in patients with underlying cardiac conditions associated with high, moderate and negligible risk of adverse outcome according to American Heart Association 2007 and with systemic comorbid conditions. In Group 2 death occurred only in 4 patients with underlying cardiac conditions associated with high-risk of adverse outcome.
Microorganisms were identified in only 60 cases in patients of Group Cases 1; 30% of them belonged to the oropharyngeal flora. in the two patients who underwent dental procedures in 3 previous months it was not possible to isolate the microorganism. In two patients affected by endo-periodontal disease endocarditis ascribable to microbic flora, arose without any dental procedures.
In the Group Cases 2, in 15 patients endocarditis was due a microorganism belonging to oral flora. Dental procedure were performed in four cases and in only one antibiotic prophylaxis was done.
Endodontic and/or parodontic diseases were present in 81.4% of patients from Group Cases 2, in 55.9% of patients from Control Group 1 , in 75% of patients from Control Group 2 and in 88% of patients of Control Group 3. Thus, patients with endodontic and/or parodontic diseases present an high risk for developing Infective Endocarditis in Control Group 1 (OR 3.692) and in Control Group 3 (OR 1.406) compared with Control Group 2 (OR 0.598).
Conclusions. Infective Endocarditis arose mainly in bicuspid aortic valve and bioprosthesis valve followed by floppy mitral valve. An important relationship exists between systemic co-morbid factors and underlying cardiac conditions at high risk for poor prognosis for Infective Endocarditis. We didn’t find association between dental care and occurrence of Infective Endocarditis due to microorganisms of the oral cavity. Nevertheless patients with endo-periodontal diseases are prone to development of endocarditis. Maintenance of optimal oral health and hygiene may reduce the incidence of bacteremia from daily activities (brushing teeth and chewing). Thus people at risk of developing Infective Endocarditis should have an high standard of oral health including endodontic and periodontal therapy
Introduzione a Memorie manoscritte intorno alle vite ed alle opere de' pittori scultori architetti eccetera d'Imola Raccolte da Gaetano Giordani nell'anno 1826
No full textIntroduzione all'importanza e il significato delle fonti antiche per la storia di Imola, e loro us
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Diagnosis and prognosis for the Ewing family of tumors
No full textBackground: Ewing's sarcoma was first described by James Ewing in 1921. It is the second most common bone sarcoma seen in children, adolescents and young adults after osteosarcoma and belongs to the group of 'small round blue cell tumors', showing an aggressive natural history. Once almost invariably fatal and treated only with palliative radiation, thanks to a multidisciplinary approach, the probability of survival at 5years is now - 65 - 75% for patients with localized disease. This percentage is no more than 20 - 25% for patients with metastatic disease at presentation. Objective: To review epidemiology, diagnosis and prognosis of Ewing's sarcoma family tumors (EFT) of bone. This entity includes a wide spectrum of tumors, from the less differentiated or classic Ewing's sarcoma to the more differentiated peripheral neuroectodermal tumor. A translocation involving the EWS gene on the chromosome 22 band q12 is characteristic of EFTs. Conclusion: A complete clinical and radiological assessment is essential for initial patient evaluation. Owing to the rarity of this entity, whenever an EFT is suspected patients should be referred to a bone tumor treatment center before a diagnostic biopsy is performed. The molecular characterization of chromosomal translocations has an important role in the diagnosis of EFT. © 2009 Informa UK Ltd. All rights reserved
Two Different Extranodal Lymphomas in an HIV+ Patient: A Case Report and Review of the Literature
No full textHuman immune deficiency virus- (HIV-) infected individuals present a higher risk of developing malignancies. Herein, we are presenting an unusual case of an untreated HIV+ patient, who developed two distinct lymphoproliferative disorders in a period of 4 years: a primary cutaneous T-cell lymphoma (PCTCL) and a diffuse large B-cell lymphoma (DLBCL) not otherwise specified (NOS), the latter developed while commencing combined antiretroviral therapy (cART). The two lymphomas also showed peculiar features: PCTCL are rarely described in HIV+ setting and particularly at such a low clinical stage, and the DLBCL showed uncommon cytology, non-GCB phenotype, EBER negativity, and absence of c-MYC translocation, all atypical features in this clinical context. This report not only confirms the increased risk of lymphoma for HIV+ patients and HIV infection being one of the major risk factors for lymphoid disorders but draws the attention on the possible occurrence of unusual features, suggesting that HIV serology should always be investigated in the clinical suspicion of lymphoma
Luigi Bacci, un actor de las relaciones culturales entre Italia y España a principios del siglo XX
No full textThe aim of this article is to define the cultural profile of Luigi Bacci: Spanish teacher, author
of a large number of Hispanic studies and protagonist of many cultural initiatives to
strengthen ties between Italy and Spain. The study of his relationships with politicians, the
approach to some of his works and the study of documents from various archives have
enabled us to approach one of those agents in cultural relations that have an incredible
passion for the other country.El objeto de este artículo es definir el perfil cultural de Luigi Bacci: profesor de español,
autor de un buen número de estudios hispánicos y protagonista de destacadas iniciativas
culturales para estrechar lazos entre Italia y España. El estudio de sus contactos con
políticos, el acercamiento a algunas de sus obras y la documentación de diferentes
archivos nos ha permitido acercarnos a uno de esos actores secundarios en las
relaciones culturales cuya única meta es su pasión increíble por el otro paí
Luigi Bacci, un actor de las relaciones culturales entre Italia y España a principios del siglo XX
No full textThe aim of this article is to define the cultural profile of Luigi Bacci: Spanish teacher, author of a large number of Hispanic studies and protagonist of many cultural initiatives to strengthen ties between Italy and Spain. The study of his relationships with politicians, the approach to some of his works and the study of documents from various archives have enabled us to approach one of those agents in cultural relations that have an incredible passion for the other country.El objeto de este artículo es definir el perfil cultural de Luigi Bacci: profesor de español, autor de un buen número de estudios hispánicos y protagonista de destacadas iniciativas culturales para estrechar lazos entre Italia y España. El estudio de sus contactos con políticos, el acercamiento a algunas de sus obras y la documentación de diferentes archivos nos ha permitido acercarnos a uno de esos actores secundarios en las relaciones culturales cuya única meta es su pasión increíble por el otro país
Treatment and prognosis for synchronous multifocal osteosarcoma in 42 patients
No full textBetween 1986 and 2002, 42 patients with synchronous multifocal osteosarcoma were treated with two different protocols of neoadjuvant chemotherapy. When feasible, the primary and secondary tumours were excised as a combined procedure. After initial chemotherapy 26 patients were excluded from simultaneous excision of all their secondary bone lesions as their disease was too advanced. In 12 patients only isolated excision of the primary lesion was possible. For 16 patients simultaneous operations were conducted to excise the primary and secondary lesions. This involved two supplementary sites in 15 patients and four additional sites in one patient. Of these, 15 attained remission but 12 relapsed and died (11 within two years). Three patients remained disease-free at five, six and 17 years. The histological response to pre-operative chemotherapy of the primary and secondary lesions was concordant in 13 of the 16 patients who underwent simultaneous operations at more than one site. The prognosis for synchronous multifocal osteosarcoma remains poor despite combined chemotherapy and surgery. The homogeneous histological responses in a large proportion of the primary and secondary lesions implies that synchronous multifocal osteosarcoma tumours are not multicentric in origin, but probably represent bone-to-bone metastases from a single tumour. ©2006 British Editorial Society of Bone and Joint Surgery
Luigi Bacci, un actor de las relaciones culturales entre Italia y España a principios del siglo XX / Luigi Bacci, an agent of cultural relations between Italy and Spain in the early twentieth century
No full textRESUMEN: El objeto de este artículo es definir el perfil cultural de Luigi Bacci: profesor de español, autor de un buen número de estudios hispánicos y protagonista de destacadas iniciativas culturales para estrechar lazos entre Italia y España. El estudio de sus contactos con políticos, el acercamiento a algunas de sus obras y la documentación de diferentes archivos nos ha permitido acercarnos a uno de esos actores secundarios en las relaciones culturales cuya única meta es su pasión increíble por el otro país. ABSTRACT: The aim of this article is to define the cultural profile of Luigi Bacci: Spanish teacher, author of a large number of Hispanic studies and protagonist of many cultural initiatives to strengthen ties between Italy and Spain. The study of his relationships with politicians, the approach to some of his works and the study of documents from various archives have enabled us to approach one of those agents in cultural relations that have an incredible passion for the other country
Livi-Bacci, Massimo (2012). A Short History of Migration. Cambridge: Polity Press. 157 págs
No full textA Short History of Migration is not only a history book: it is also a thought-provoking analysis of the present and future of migration which includes some policy suggestions and interesting reflections about the evolution of migration policies and demographics in Europe from a longue durée perspective. Almost a decade after its publication, the predictions of the book are still up-to-date and relevant to the current debates on migration in Europe. The author, Massimo Livi-Bacci (b. 1936) is one of the leading voices in the field of demography and a Professor Emeritus of Demography in the University of Florence. During his prolific career, he has published books and articles about the historical demographic evolution of colonial America, Mediterranean countries such as Italy and Spain, as well as introductory handbooks to global historic demography such as A Concise History of the World Population.A Short History of Migration no es solo un libro de historia: también es un análisis que invita a la reflexión del presente y el futuro de la migración que incluye algunas sugerencias de política y reflexiones interesantes sobre la evolución de las políticas de migración y la demografía en Europa desde una perspectiva de longue durée. . Casi una década después de su publicación, las predicciones del libro siguen estando actualizadas y son relevantes para los debates actuales sobre la migración en Europa. El autor, Massimo Livi-Bacci (n. 1936) es una de las principales voces en el campo de la demografía y profesor emérito de demografía en la Universidad de Florencia. Durante su prolífica carrera, ha publicado libros y artículos sobre la evolución demográfica histórica de la América colonial, países mediterráneos como Italia y España, así como manuales introductorios a la demografía histórica global como A Concise History of the World Population
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