1,387,331 research outputs found
Content Validity of the GAD-7 Through Expert and Student Perspectives
No full textopenAs one of the most prevalent mental health concerns among university students, Generalized Anxiety Disorder (GAD) can significantly impact the academic and social life of students, as well as their overall well-being. Early identification and intervention can help minimize the negative impacts of the disorder, therefore highlighting the need for effective and valid screening tools within the clinical setting. This study aims to examine the content validity of the GAD-7 questionnaire, one of the most well known and widely used questionnaires for identifying and assessing Generalized Anxiety Disorder (GAD), through the application of Formal Content Validity Analysis (FCVA), within the framework of Formal Psychological Assessment (FPA), which is a novel procedure that combines several techniques of assessment within various fields. The research aims to achieve this through comparing responses between psychology students of different levels of education and an expert in order to identify any differences in interpretation and to determine the extent to which the items accurately assess the intended symptoms, which were selected according to the DSM-5 criteria and relevant literature. For this purpose, a Boolean matrix in the form of a questionnaire was created. The final questionnaire consisted of 56 questions in total, with the 7 items from the GAD-7 and 8 selected symptoms of GAD. The participants were asked to indicate whether they believed the given item from the GAD-7 assessed the presented symptom accurately, for each of the 8 chosen attributes. The agreement between the responses of the students were calculated, and these responses were then compared with those of the expert’s. Lastly, the findings of the analysis are presented
GAD-7 item and sum score characteristics.
No full textBackgroundAnxiety is a frequent condition in patients and in the general population. The aim of this study was to investigate changes in anxiety over time and to test several psychometric properties of the Generalized Anxiety Disorder Screener (GAD-7) from a longitudinal perspective.MethodsThe GAD-7 was included in an examination with two waves, six years apart. The study sample (n = 5355) was comprised of representatively selected adults from the general population with a mean age of 57.3 (SD = 12.3) years.ResultsDuring the 6-year time interval, anxiety increased significantly from 3.28 ± 3.16 (t1) to 3.66 ± 3.46 (t2). Confirmatory factor analyses proved the longitudinal measurement invariance of the GAD-7. Reliability of the GAD-7 was established both for the cross-sectional and the longitudinal perspective. The test-retest correlation was r = 0.53, and there were no substantial sex or age differences in these coefficients of temporal stability. The mean changes in anxiety were similar for males and females, and there was no linear age trend in the changes measured by the GAD-7. Changes in anxiety over the 6-year period were correlated with changes in satisfaction with life (r = -0.30), bodily complaints (r = 0.31), and the mental component of quality of life (r = -0.48).ConclusionThe GAD-7 is a suitable instrument for measuring changes in anxiety. Age and gender have only minor significance when interpreting change scores.</div
Madrid is Browning: A conversation with Gad Yola
No full textAfro-LatinX drag artist Gad Yola was born in Lima in 1995, migrated to Spain in 2006, and began performing in Madrid in 2017, a year marked by the rise of Spanish nationalism. This interview acquaints us with Gad Yola's artistic vision and practices. It orients us toward the growing presence of “Brown art” in the Peninsula, taking a deeper look at the work of artists who declare themselves “migrants” or “Migrantas” and examining the use of LatinX’s X in Spain. Gad Yola’s career includes performances such as “El drag es marrón” (“Drag Is Brown”), the exhibition “Hypernariz” (“Hypernose”), and the music videos “No exotice” (“Don’t Exoticize”), “Aguanta Migranta” (“Hang in There, Mx. Migrant”), “Travesti del Perú” (“Trans from Peru”), and “Problemática” (“Troublemaker”). The analysis of these works focuses on the use of pop-reggaeton-cumbia rhythms, the politicization of Gad Yola’s fashion, and her references to colonial history and Spanish, Peruvian, and US pop culture. LatinX’s transatlantic “X” emerges on social media and webs across these geographies, accompanying Gad Yola’s oeuvre and the work of other artists from the Spanish capital with whom she has collaborated, including Chenta Tsai Tseng, Samantha Hudson, and the drag families Casa Drag Latina and House of Gad. From Madrid’s bars, squat houses, and museums, Gad Yola reclaims, invigorates, and re-conceptualizes such referents like Peruvian artist and philosopher Giuseppe Campuzano, while also coming up with characters like “Gad Bunny” and “Gadyoncé,” thus embodying a Global South LatinXness. Gad Yola’s queer, anti-racist art evokes a Global Iberian LatinX that bridges these terms and expands them, reconfiguring the cultural scene in Spain and beyon
Gad Landau Family Collection. 1878-1918
No full textThe collection contains various photographs of family members of Gad (Gustav) Landau and a family tree of his wife's family, the Heinrichsdorff-Baums.There is a good quality original photo of a wedding in Lübeck of Dina Mecklenburg and Maurice Blitz of Amsterdam. A key with the names of the people in the photograph is supplied. The following names are mentioned: Carlebach, Mecklenburg, Adler, Rothschild, Landau, Meyer, Baer, Goldschmidt.Gad LandauGustav (Gad) Landau married Lili Baum. Her father was physician Dr. Richard Baum (1878-1918) and her mother was Elisabeth nee Heinrichsdorff.processed for digitization.Sent for digitizationReturned from digitizationLinked to online manifestationdigitize
Association between Antibodies to the MR 67,000 Isoform of Glutamate Decarboxylase (GAD) and Type 1 (Insulin-Dependent) Diabetes Mellitus with Coexisting Autoimmune Polyendocrine Syndrome Type II
No full textBy using an immunoprecipitation assay, we analysed reactivity of autoantibodies to human recombinant GAD65 and GAD67 in sera from patients with autoimmune polyendocrine syndrome Type II (APS II) with and without Type 1 (insulin-dependent) diabetes mellitus (IDDM) compared to patients with organ-specific autoimmunity. Overall antibodies to GAD65 were correlated with IDDM in all study groups, whereas GAD67 antibodies were associated with IDDM when APS II coexists. Antibodies to GAD65 and GAD67 were detected in 13 (44.8%) and 7 (24.1%) out of 29 APS II patients with IDDM, but in only 4 (13.8%) and 2 (6.9%) out of 29 APS II patients without IDDM, respectively (p < 0.05). In short-standing IDDM (< 1 year), antibodies to GAD67 were significantly more frequent in patients with APS II (5 of 9 [55.6%] subjects) compared to matched diabetic patients without coexisting polyendocrinopathy (1 of 18 [5.6%] subjects) (p < 0.02). The levels of GAD65 (142 ± 90 AU) and GAD67 antibodies (178 ± 95 AU) were significantly higher in patients with polyglandular disease than in patients with isolated IDDM (91 ± 85 AU and 93 ± 57 AU) (p < 0.02). Interestingly, all 11 GAD67 antibody positive subjects also had GAD65 antibodies (p < 0.0001), and in 10 of 11 anti-GAD67 positive sera the GAD67 antibodies could be blocked by either GAD67 or GAD65, suggesting the presence of cross-reactive autoantibodies. No correlation was observed between GAD antibodies and age, sex or any particular associated autoimmune disease, besides IDDM. GAD antibodies were present in only 1 of 6 (16.7%) patients with APS Type I, in 1 of 26 (3.9%) patients with autoimmune thyroid disease but in none of the patients with Addison's disease (n = 16), pernicious anaemia (n = 7) or normal controls (n = 50). Our data suggest distinct antibody specificities reactive to GAD isoforms in APS II and IDDM, which might reflect different mechanisms of autoimmune response in IDDM with coexisting autoimmune polyendocrine autoimmunity
Prevalence of autoantibodies to the 65- and 67-kD isoforms of glutamate decarboxylase in insulin-dependent diabetes mellitus
No full textWe investigated the presence of autoantibodies to baculovirus-expressed human recombinant 65- and 67-kD isoforms of glutamate decarboxylase (GAD65 and GAD67) in insulin-dependent diabetes mellitus (IDDM). In the immunoprecipitation test using [35S]methionine-labeled GADs antibodies to GAD65 were detected in 13/15 (87%) islet cell antibody (ICA)-positive and in 1/35 (2.9%) ICA-negative first-degree relatives of patients with IDDM, in 6/11 (54.5%) ICA-positive nondiabetic schoolchildren, and in 35/50 (70%) patients with newly diagnosed IDDM. GAD67 antibodies were positive only in five (33%) of the ICA-positive relatives (P 10 yr). In all study groups antibodies to GAD67 were only detected in GAD65 antibody-positive sera. An immunotrapping enzyme activity assay for GAD65 antibodies was positive in 64/75 (85.3%) of sera that were GAD antibody positive in the immunoprecipitation test (r = 0.870, P < 0.0001). In two (2.7%) sera GAD65 antibodies that block GAD enzyme activity were found. Our data suggest that antibodies to GAD65 but not to GAD67 represent sensitive markers for preclinical and overt IDDM. The immunotrapping assay here described represents a valuable technique for specific and sensitive screening for GAD antibodies
metapsy-project/data-gad-psyctr: Version 23.0.2
No full text<h2><strong>The <code>data-gad-psyctr</code> dataset</strong> </h2>
<p>The <code>data-gad-psyctr</code> dataset is a meta-analytic research domain <a href="https://docs.metapsy.org/uploads/ebmental-2022-300509.pdf">MARD</a>) on psychotherapy for generalized anxiety disorder (GAD). This MARD is part of the <a href="https://www.metapsy.org/">Metapsy project</a>. The dataset contains study information and effect size data of trials that report the effect of psychotherapy on GAD symptoms. This dataset includes <strong>psychotherapy vs. control ('psy vs ctr')</strong> comparisons. Effect sizes are provided for outcomes at post-test. The results of a network meta-analysis using this database can be read in this <a href="https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2810866">published article</a>.</p>
<p>The dataset follows the <a href="https://docs.metapsy.org/data-preparation/format/">Metapsy data standard</a>. All included information has been independently extracted two researchers. Risk of bias ratings were conducted using the Cochrane Collaboration Risk of Bias Tool (Version 2).</p>
metapsy-project/data-gad-psyctr: Version 23.0.0
No full text<h2><strong>The <code>data-gad-psyctr</code> dataset</strong> </h2>
<p>The <code>data-gad-psyctr</code> dataset is a meta-analytic research domain <a href="https://docs.metapsy.org/uploads/ebmental-2022-300509.pdf">MARD</a>) on psychotherapy for generalized anxiety disorder (GAD). This MARD is part of the <a href="https://www.metapsy.org/">Metapsy project</a>. The dataset contains study information and effect size data of trials that report the effect of psychotherapy on GAD symptoms. This dataset includes <strong>psychotherapy vs. control ('psy vs ctr')</strong> comparisons. Effect sizes are provided for outcomes at post-test. The results of a network meta-analysis using this database can be read in this <a href="https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2810866">published article</a>.</p>
<p>The dataset follows the <a href="https://docs.metapsy.org/data-preparation/format/">Metapsy data standard</a>. All included information has been independently extracted two researchers. Risk of bias ratings were conducted using the Cochrane Collaboration Risk of Bias Tool (Version 2).</p>
metapsy-project/data-gad-psyctr: Version 23.0.4
No full text<h2><strong>The <code>data-gad-psyctr</code> dataset</strong> </h2>
<p>The <code>data-gad-psyctr</code> dataset is a meta-analytic research domain <a href="https://docs.metapsy.org/uploads/ebmental-2022-300509.pdf">MARD</a>) on psychotherapy for generalized anxiety disorder (GAD). This MARD is part of the <a href="https://www.metapsy.org/">Metapsy project</a>. The dataset contains study information and effect size data of trials that report the effect of psychotherapy on GAD symptoms. This dataset includes <strong>psychotherapy vs. control ('psy vs ctr')</strong> comparisons. Effect sizes are provided for outcomes at post-test. The results of a network meta-analysis using this database can be read in this <a href="https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2810866">published article</a>.</p>
<p>The dataset follows the <a href="https://docs.metapsy.org/data-preparation/format/">Metapsy data standard</a>. All included information has been independently extracted two researchers. Risk of bias ratings were conducted using the Cochrane Collaboration Risk of Bias Tool (Version 2).</p>
metapsy-project/data-gad-psyctr: Version 23.0.3
No full text<h2><strong>The <code>data-gad-psyctr</code> dataset</strong> </h2>
<p>The <code>data-gad-psyctr</code> dataset is a meta-analytic research domain <a href="https://docs.metapsy.org/uploads/ebmental-2022-300509.pdf">MARD</a>) on psychotherapy for generalized anxiety disorder (GAD). This MARD is part of the <a href="https://www.metapsy.org/">Metapsy project</a>. The dataset contains study information and effect size data of trials that report the effect of psychotherapy on GAD symptoms. This dataset includes <strong>psychotherapy vs. control ('psy vs ctr')</strong> comparisons. Effect sizes are provided for outcomes at post-test. The results of a network meta-analysis using this database can be read in this <a href="https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2810866">published article</a>.</p>
<p>The dataset follows the <a href="https://docs.metapsy.org/data-preparation/format/">Metapsy data standard</a>. All included information has been independently extracted two researchers. Risk of bias ratings were conducted using the Cochrane Collaboration Risk of Bias Tool (Version 2).</p>
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