1,721,098 research outputs found
The amino aldehydes produced by spermine and spermidine oxidation with maize polyamine oxidase have anti-leishmanial effect
Control of congenital toxoplasmosis in Italy: The project of the Istituto Superiore di Sanità
Article in Italia
Nested PCR Assay for Specific Detection of Entamoeba hystolytica and E.dispar in faecal samples
STUDIES ON CANINE LEISHMANIASIS CONTROL .1. EVOLUTION OF INFECTION OF DIFFERENT CLINICAL FORMS OF CANINE LEISHMANIASIS FOLLOWING ANTIMONIAL TREATMENT
Incidence and time course of Leishmania infantum infections examined by parasitological, serologic, and nested-PCR techniques in a cohort of naive dogs exposed to three consecutive transmission seasons.
Most experience in the comparison of diagnostic tools for canine leishmaniasis comes from cross-sectional
surveys of dogs of different ages and breeds and in cases with unknown onset and duration of leishmaniasis.
A longitudinal study was performed on 43 beagle dogs exposed to three transmission seasons (2002 to 2004)
of Mediterranean leishmaniasis and examined periodically over 32 months through bone marrow microscopy
and nested PCR (n-PCR), lymph node culture, serology (immunofluorescent-antibody test), and evaluation of
clinical parameters. Starting from January 2003, the highest rate of positives was detected by n-PCR at all
assessments (from 23.3% to 97.3%). Sensitivities of serologic and parasitological techniques were lower but
increased with time, from 15.8% to 75.0 to 77.8%. Some dogs that tested positive by n-PCR but negative by other
tests (“subpatent infection”) remained so until the end of the study or converted to negative in subsequent
assessments, whereas all dogs with positive serology and/or microscopy/culture (“asymptomatic patent infection”)
exhibited progressive leishmaniasis; 68% of them developed clinical disease (“symptomatic patent
infection”) during the study, at 7 (range, 3 to 14) months after being positive to all tests. Postexposure infection
incidences were high and were significantly different between 2002 and 2003 exposures (39.5% and 91.7%,
respectively). The time course of infection was highly variable in each dog, with three patterns being identified:
(i) rapid establishment of a patent condition (0 to 2 months from detection of infection); (ii) a prolonged
subpatent condition (4 to 22 months) before progression; and (iii) a transient subpatent condition followed by
10 to 21 months of apparent Leishmania-negative status before progression
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
LEISHMANIA-INFANTUM INFECTION-RATES IN PHLEBOTOMUS-PERNICIOSUS FED ON NATURALLY INFECTED-DOGS UNDER ANTIMONIAL TREATMENT
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