118,295 research outputs found
La fortuna critica di Giovannoni negli scritti e nelle opere di Angiolo Mazzoni in Colombia per il restauro architettonico e urbano della Candelaria di Bogotá
No full textPaper in the International Proceedings “Gustavo Giovannoni e l’architetto integrale” by Francesco Moschini and Giuseppe Bonaccorso, Accademia di San Luca, Roma 201
Tracce di un’algebra di Lindenbaum in una relazione d’ordine introdotta nell’Arithmetica realis di Pietro Mengoli
No full textGustavo Giovannoni tra storia e progetto. Bilancio di una mostra
No full textIl saggio sintetizza i contenuti della mostra Gustavo Giovannoni tra storia e progetto, organizzata dal Centro di Studi per la Storia dell'Architettura (Roma-Casa dei Crescenzi), in collaborazione con la Soprintendenza Speciale per il Colosseo iI Museo nazionale romano e l'area archeologica di Roma, allestita dal 4 febbraio al 15 marzo 2016 allestita nei locali del Museo delle Terme di Diocleziano. In questa occasione è stata presentata per la prima volta al pubblico, una selezione ragionata del materiale presente nel ricchissimo archivio conservato presso la Casa dei Crescenzi, sede del Centro di Studi per la Storia dell’Architettura, fondato da Giovannoni stesso nel 1939. La mostra dislocata in 5 sale ha mostrato i vari aspetti della poliedrica figura e attività di Gustavo Giovannoni: la biografia (prima sala), il rapporto con la storia (seconda sala), la sua produzione architettonica e attività urbanistica (terza sala), l'attività nel campo del restauro (quarta sala), i rapporti con le svariate istituzioni (quinta sala)
Use of homologous and heterologous gene expression profiling tools to characterize transcription dynamics during apple fruit maturation and ripening
No full textAbstract Background Fruit development, maturation and ripening consists of a complex series of biochemical and physiological changes that in climacteric fruits, including apple and tomato, are coordinated by the gaseous hormone ethylene. These changes lead to final fruit quality and understanding of the functional machinery underlying these processes is of both biological and practical importance. To date many reports have been made on the analysis of gene expression in apple. In this study we focused our investigation on the role of ethylene during apple maturation, specifically comparing transcriptomics of normal ripening with changes resulting from application of the hormone receptor competitor 1-Methylcyclopropene. Results To gain insight into the molecular process regulating ripening in apple, and to compare to tomato (model species for ripening studies), we utilized both homologous and heterologous (tomato) microarray to profile transcriptome dynamics of genes involved in fruit development and ripening, emphasizing those which are ethylene regulated. The use of both types of microarrays facilitated transcriptome comparison between apple and tomato (for the later using data previously published and available at the TED: tomato expression database) and highlighted genes conserved during ripening of both species, which in turn represent a foundation for further comparative genomic studies. The cross-species analysis had the secondary aim of examining the efficiency of heterologous (specifically tomato) microarray hybridization for candidate gene identification as related to the ripening process. The resulting transcriptomics data revealed coordinated gene expression during fruit ripening of a subset of ripening-related and ethylene responsive genes, further facilitating the analysis of ethylene response during fruit maturation and ripening. Conclusion Our combined strategy based on microarray hybridization enabled transcriptome characterization during normal climacteric apple ripening, as well as definition of ethylene-dependent transcriptome changes. Comparison with tomato fruit maturation and ethylene responsive transcriptome activity facilitated identification of putative conserved orthologous ripening-related genes, which serve as an initial set of candidates for assessing conservation of gene activity across genomes of fruit bearing plant species.</p
Highly fluorescent protein labeling using dendritic peptide derivatives
No full textNon-specific fluorescent dyes and photosensitizers are routinely used in clinical practice for the photodetection and photoablation of superficial lesions. Future applications in photomedicine are likely to rely on the selective delivery of photoactive compounds to diseased areas, using specific targeting agents such as antibodies. This fact underlines the need for methods that allow the chemically defined conjugation of several photoactive molecules to a single protein 'vehicle', with full retention of binding affinity. Here, we present methods for the site-specific fluorescent labeling of proteins using dendritic peptides, which had been chemically modified with multiple molecules of fluorescein. Branched peptide derivatives can be stably conjugated to proteins either by reaction with suitable free reactive groups or by using the high-affinity non-covalent interaction between calmodulin and a specific binding peptide. Chemical modification of proteins with one, two or four molecules of fluorescein resulted in a proportional increase in protein fluorescence
The micro-foundations of Corporate Purpose:Performance management in dynamic environments
No full textThis paper examines the micro-foundations of ‘corporate purpose’, that is the enduring reason for being of a corporation in relation to society. While the relevance of corporate purpose has been widely recognized, its practical enactment by managers at the operating level remains problematic, particularly in dynamic environments. By relying upon the field study of a leading Italian group in the food industry, and the literature on the micro-foundations of institutions, we explore the role of a performance management system (PMS) in mobilizing corporate purpose in specific practical situations at the management level, while the organization faces the demands coming from the external environment. We show that the PMS can be drawn upon by managers as a set of tools and practices through which purpose is situated at the micro-level into actions, decisions, and material artefacts that come together in a ‘social situation’. Here, the PMS enables managers to recognize a ‘situation’ for enacting different aspects of purpose through interactions, filling it with evolving meanings, while sustaining its connections with global development needs
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Control vs. Creativity
No full textThey’re eternal questions in business: Does management control
kill creativity? How can organizations manage efficiency within
innovating processes? Do control and creativity call for a balance
within processes of innovation—or is balancing a bad
idea? The answers to these questions are probably bedeviling
entrepreneurs and executives everywhere around the world.
While a controlled working environment has its advantages, too
much control can hamper the creativity, as well as the ability to
innovate, that leads to new products and to growth and profitability.
The article addresses these issues by offering
insights from a medium-sized company in the fashion industry
that has used formal and informal control tools to manage its
need for both standardization and innovation
When Creativity Meets Control: A Fashion Industry Case Study
No full textIs innovation hindered by management efforts to channel and control creativity? Many would argue that management control systems that are inappropriately designed and used can inhibit innovation. This being true, companies need to find ways to manage the delicate balance between creativity and control. The fashion industry provides an interesting setting for exploring creativity, innovation, and control, as this case study of a medium-sized Italian fashion company shows. © 2012 Wiley Periodicals, Inc. © 2012 Wiley Periodicals, Inc
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