1,722,298 research outputs found
De Giorgi F., La storia e i maestri. Storici cattolici italiani e storiografia sociale dell'educazione, La Scuola, Brescia 2005
Recensione al volume: De Giorgi F., La storia e i maestri. Storici cattolici italiani e storiografia sociale dell'educazione, La Scuola, Brescia 200
Expression-based reverse engineering of plant transcriptional networks
Regulation of gene transcription plays a major role in mediating cellular responses and physiological behavior in all known organisms. The finding that similar genes are often regulated in a similar manner (co-regulated or "co-expressed") has directed several "guilt-by-association" approaches in order to reverse-engineer the cellular transcriptional networks using gene expression data as a compass. This kind of studies has been considerably assisted in the recent years by the development of high-throughput transcript measurement platforms, specifically gene microarrays and next-generation sequencing. In this work, several approaches are described for improving the extraction and interpretation of the information contained in plant transcriptional data, obtained from microarrays or through next generation sequencing. Applications of these theoretical approaches, ranging from Pearson correlation to LASSO and hybrid methods, are described for the reverse engineering of tuber growth transcriptional networks, for the prediction of essential genes and in the task of defining the full transcriptome of the extremophile plant Thellungiella salsuginea
Climate Change Projections for the Mediterranean Region
We present a review of climate change projections over the Mediterranean region based on the most recent and comprehensive ensembles of global and regional climate change simulations completed as part of international collaborative projects. A robust and consistent picture of climate change over the Mediterranean emerges, consisting of a pronounced decrease in precipitation, especially in the warm season, except for the northern Mediterranean areas (e.g. the Alps) in winter. This drying is due to increased anticyclonic circulation that yields increasingly stable conditions and is associated with a northward shift of the Atlantic storm track. A pronounced warming is also projected, maximum in the summer season. Interannual variability is projected to mostly increase especially in summer, which, along with the mean warming, would lead to a greater occurrence of extremely high temperature events. The projections by the global and regional model simulations are generally consistent with each other at the broad scale. However, the precipitation change signal produced by the regional models shows substantial orographically-induced fine scale structure absent in the global models. Overall, these change signals are robust across forcing scenarios and future time periods, with the magnitude of the signal increasing with the intensity of the forcing. The intensity and robustness of the climate change signals produced by a range of global and regional climate models suggest that the Mediterranean might be an especially vulnerable region to global change
Lorenzo Milani (1923-1967)
Il contributo ripercorre dal punto di vista storico-educativo la biografia di don Lorenzo Milani, mettendo in luce i fondamenti della "pedagogia della parola" e il rapporto tra istruzione ed emancipazione sociale
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
La permanenza del Cristianesimo nell'età contemporanea
Il contributo analizza le forme di presenza del Cristianesimo nell'età contemporanea, con una particolare attenzione ai temi della laicizzazione e della secolarizzazion
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