1,721,002 research outputs found
Palliation of inoperable carcinoma of the esophagus and esophago-gastric joint with metallic self-expanding stent.
No full textValue of chromo-magnification endoscopy and targeted biopsies in the diagnosis of celiac disease with previously negative histology: a preliminary study
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Value of Chromo-Magnification Endoscopy and Targeted Biopsies in the Diagnosis of Celiac Disease with Previously Negative Histology: A Preliminary Study
Annalisa Pascariello, Carolina Ciacci, Ilaria Russo, Luca Magno, Giuseppe Galloro, Paola Iovino
Introduction. Chromoendoscopy with magnification has been previously demonstrated to be valuable in assessing the degree of intestinal villous atrophy in patients with suspected celiac disease. Aim and Methods. The aim of this study is to determine the accuracy of these methods in association with targeted biopsies in the diagnosis of suspected celiac disease in cases of positive serology and previous negative histology.13 patients (12 females, range 17-43 years) with a positive/border-line value of anti-tissue transglutaminase antibodies and a previous negative histopathologic evaluation underwent upper endoscopy for the purpose of obtaining duodenal targeted biopsy specimens. In all patients we performed chromoendoscopy with indigo carmine sprayed onto the duodenal mucosa and, thereafter, a full magnification of duodenal mucosa.
A villous pattern score was allocated for each patients at the end of procedure as definitely present = 1, partially present =2, definitely absent = 3. Biopsies were taken from the most abnormal-looking mucosa or apparent normal when present
using rocking biopsy forceps and mounted on filter paper and put into formalin for histological assessment. Three more samples were collected for In Vitro challenge with gluten-derived toxic peptides . Frozen sections of the biopsies were then
evaluated by immunohistochemistry. Results. 76.9%of subject had a positive value of anti-tissue transglutaminase antibodies while 23.1 % had borderline value. The chromoendoscopic results showed normal villous pattern in 46.2%(6 pts), partially
present 15.4%(2 pts ), definitively absent 38.5% (5pts). A significant positive correlation was found between a positive value of anti-tissue transglutaminase antibodies and the endoscopic score of villous pattern (Spearman, r = 0,56, p < 0.05).
In Vitro challenge was positive in 50% of normal villous pattern and in all patients with definitively absent villous pattern.
Conclusions. This preliminary study suggest that chromoendoscopy with magnification may disclose with accuracy severe villous atrophy but it may have a great value in evaluating selected series of patients with doubtful diagnosis of celiac disease
Valutazione dei reflussi acidi e non acidi con pHimpedenzometria delle 24h in pazienti obesi. Studio preliminare.
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Palliation of inoperable carcinoma of the esophagus and esophago-gastric joint with metallic self-expanding stent.
No full text
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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