1,721,065 research outputs found
Designing the school-family alliance from an inclusive and sustainable perspective: an operational proposal.
The construction of the pedagogical alliance between school and family represents a central aspect of any inclusive practice that wishes to favour the accessibility of all students to places of life and that is oriented towards guaranteeing a fair and quality education. There emerges, therefore, the need to design the schoolfamily relationship starting from a reference structure that acts as a progressive and organised framework. The aim of this paper is to review some interpretative models for the construction of such an alliance with the ultimate aim of sharing of an operational proposal
Characterization of different cell populations isolated from rat testis peritubular cells
Calcium-, phospholipid-dependent protein kinase activity of cultured rat Sertoli cells and its modifications by vitamin A
The activity of the calcium-, phospholipid-dependent protein kinase (PKc) was partially characterized in Sertoli cell cultures prepared from 20-day-old rats. The calcium dependency, the requirements for phosphatidylserine and diolein, as well as the Km for ATP and for the tumor promoter TPA, were determined in total cell extracts. The specific activity of PKc was almost 3-fold higher in the soluble than in the particulate fraction of Sertoli cells. Treatment of cultured Sertoli cells with retinol inhibited, within 1 h of treatment, both the soluble and the particulate fraction-associated PKc activity, with an IC50 of 0.1 microM. Partial inhibition of PKc activity was obtained treating Sertoli cell cultures with FSH, while testosterone was ineffective. However, both FSH and testosterone potentiated the inhibitory effect of retinol. Less differentiated Sertoli cells, obtained from 8-day-old rats, displayed higher PKc activity and a pattern of subcellular distribution of the enzyme opposite to that of Sertoli cells obtained from 20-day-old rats. These data suggest that the actual PKc activity of rat Sertoli cells be negatively regulated by retinol and, spontaneously, during the progression of Sertoli cell differentiation
Retinoic Acid Synthesis from Holo-Cellular Retinol Binding Protein in the Somatic Cells of Rat Testis.
Flessibilità e adattamento al cambiamento nella trasposizione didattica a distanza
Il lavoro presenta una lettura in chiave semplessa del processo di insegnamento- apprendimento nell’ambito della didattica a distanza e una riflessione sulle di- namiche educative ridefinite dalle tecnologie digitali. I mutati scenari sociali, politici ed economici correlati al sopraggiungere dell’inaspettata emergenza sa- nitaria, hanno sollecitato, anche in ambito educativo, la ricerca di pratiche didat- tiche flessibili ed innovative, la rivisitazione dei tempi e dei luoghi della didat- tica e la rimodulazione del modus operandi del docente la cui professionalità si esplica nel suo ruolo proattivo, trasformativo e nella sua capacità, talvolta, in- consapevole, di destrutturare itinerari conoscitivi ed esperienziali generando nuove ed originali forme di agire didattico. L’esperienza svolta presso l’Univer- sità degli Studi del Sannio di Benevento nel percorso formativo dei 24 CFU attraverso la somministrazione di un questionario a centottantatré studenti, ed estesa anche a cinquantadue docenti campani, disciplinaristi e non di sostegno, propone una riflessione sul tema della trasposizione didattica in modalità e-lear- ning a partire da una progettualità educativo-didattica in linea con il bisogno del discente di autodeterminazione dei propri apprendimenti
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