1,720,967 research outputs found
Application of a film method for microbial monitoring of cosmetic raw materials
No full textThe possibility of using a film plate-count method, instead of the too complex and lengthy traditional methods, has been evaluated in cosmetic products. Petrifilm® is a ready-to-use system for detecting any microbial contamination. It consists of a flexible polypropylene film supporting on suitable dehydrated medium, a second support containing guar (a cold-water soluble gel-former) and an indicator on the internal surface. Petrifilm® proved to have a good sensitivity and to be more convenient than the method recommended by the Italian National Pharmacopoeia. Results showed that it is possible to detect microbial and fungal contamination of raw materials of natural origin, which are frequently used in cosmetic preparations. Positive results were obtained on finished products (oil in water emulsions)
Possibilità di utilizzo di un sistema a film reidratabile nel controllo microbiologico di preparati farmaceutici
No full textAim of this work was to verify the possibility of using a ready-to-use plate-count method to detect the microbial and fungine contamination on pharmaceutical products. The system consists of a flexible polypropylene film, supporting a suitable dehydrated medium, a second support containing guar, and an indicator on the internal surface. 33 raw materials, 11 natural origin materials, 20 medicinal products of officinal formula and 18 homeopatic products were analysed. As reference we chose the Italian Pharmacopoiea method. The two methods were comparable, showing no statistical differences, but for one case. This method, if our data will be further confirmed, could be used by the pharmacies and by the homeopathic industries
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Physicochemical characterization of a new starch derivative proposed as disintegrant agent
No full text
Cyclopenta[e][1,5]benzodiazepin-10(9H)-one derivatives as CNS depressant agents
No full textA series of dialkylaminoalkyl derivatives of cyclopenta[e][1,5] benzodiazepin-10(9H)-one (E1-4) and its 6-chloro derivative (E5-8) was prepared to evaluate their CNS activity in comparison with that of isosteric pyridodiazepinones (A1-4) previously described. The results of the pharmacological screening show a significant depressant activity more remarkable in 6-chloro derivatives, which also revealed a high and lasting analgesic activity. The replacement of pyridine with benzene nucleus did not show any significant or homogeneous activity variation
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