1,543 research outputs found
Licorice (<i>Glycyrrhiza glabra</i>, <i>G. uralensis</i>, and <i>G. inflata</i>) and Their Constituents as Active Cosmeceutical Ingredients
No full textThe interest in plant extracts and natural compounds in cosmetic formulations is growing. Natural products may significantly improve cosmetics performance since they have both cosmetic and therapeutic-like properties, known as cosmeceutical effects. Glycyrrhiza genus, belonging to the Leguminosae family, comprises more than 30 species, widely distributed worldwide. The rhizomes and roots are the most important medicinal parts currently used in pharmaceutical industries and in the production of functional foods and food supplements. In the last few years, the interest in their potential activities in cosmetic formulations has greatly increased. Glycyrrhiza spp. extracts are widely implemented in cosmetic products for their good whitening effect. The biological effects of Glycyrrhiza extracts are especially ascribable to the occurrence of specialized metabolites belonging to the flavonoid class. This review focuses on the botany and the chemistry of the main investigated Glycyrrhiza spp. (G. glabra, G. uralensis, and G. inflata) along with their cosmeceutical activities categorized as skin anti-aging, photoprotective, hair care, and anti-acne. It has been highlighted how, along with Glycyrrhiza extracts, three main flavonoids namely licochalcone A, glabridin, and dehydroglyasperin C are the most investigated compounds. It is noteworthy that other molecules from licorice show potential cosmeceutical effects. These data suggest further investigations to clarify their potential value for cosmetic industries
Antonio Montoro y San Juan de la Cruz
No full textThe aim of this article is to illustrate the importance of the life and work of San Juan de la Cruz in the literature of the poet, novelist and playwright Antonio Montoro (1884-1966), an author whose artistic figure has not yet been recovered with all the attention he deserves. In our work we will proceed to comment on the different writings that Montoro wrote about the mystic of Fontiveros, also offering extensive textual fragments still unpublished, with the aim of studying the link between Montoro’s literary ideas and the great Spanish Golden Age tradition.Objeto del presente artículo es ilustrar la importancia de la vida y obra de San Juan de la Cruz en la literatura del poeta, novelista y autor teatral Antonio Montoro (1884-1966), autor cuya trayectoria literaria y periodística no se ha recuperado todavía con toda la atención que merece. En nuestro trabajo se procederá a comentar los diferentes escritos que Antonio Montoro redactó sobre el místico de Fontiveros, ofreciendo además amplios fragmentos textuales aún sin publicar, con el objetivo de estudiar el vínculo de las ideas literarias del autor con la gran tradición aurisecular española
36. Montoro Inferiore, Preturo (AV). Grotta di San Michele
No full textAnalisi degli affreschi evenescenti della chiesa in grotta di San Michele a Preturo di Montoro Inferiore: analisi iconografica e revisione cronologica
Antonio Montoro y San Juan de la Cruz
No full textObjeto del presente artículo es ilustrar la importancia de la vida y obra de San Juan de la Cruz en la literatura del poeta, novelista y autor teatral Antonio Montoro (1884-1966), autor cuya trayectoria literaria y periodística no se ha recuperado todavía con toda la atención que merece. En nuestro trabajo se procederá a comentar los diferentes escritos que Antonio Montoro redactó sobre el místico de Fontiveros, ofreciendo además amplios fragmentos textuales aún sin publicar, con el objetivo de estudiar el vínculo de las ideas literarias del autor con la gran tradición aurisecular española.The aim of this article is to illustrate the importance of the life and work of San Juan de la Cruz in the literature of the poet, novelist and playwright Antonio Montoro (1884-1966), an author whose artistic figure has not yet been recovered with all the attention he deserves. In our work we will proceed to comment on the different writings that Montoro wrote about the mystic of Fontiveros, also offering extensive textual fragments still unpublished, with the aim of studying the link between Montoro’s literary ideas and the great Spanish Golden Age tradition
Positive control as a validation strategy in multiblock analysis: an implementation to a breast cancer subtypes study
No full textFil: Rocha, Darío G. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina.Fil: González Montoro, Aldana. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía, Física y Computación; Argentina.Fil: González Montoro, Aldana. Consejo Nacional de Investigaciones Científicas y Técnicas. CIEM; Argentina.Fil: Prato, Laura. Universidad Nacional de Villa María; Argentina.Fil: Fernández, Elmer. Universidad Nacional de Villa María; Argentina.In molecular biology, modern technologies generate large databases of certain phenomena allowing to studythe same group of individuals from different omics views. This provides data blocks that can be analyzed together throughtechniques, such as Multiple Factor Analysis (MFA), that allow a multidimensional exploratory approach. When two datablocks provide different information on the same phenomenon, the differences observed could arise from actual biologicalfacts but, they could as well be a result of a confounding factor such as the technology used to obtain the data. In this study,we used MFA to analyze two data blocks (a transcriptomic block and a proteomic block) of gene expression on breast cancerpatients, and added a third data block (also transcriptomic but gathered through a different technology) as a positivecontrol. Both transcriptomic data blocks provided highly similar information between them, but different to the informationprovided by the proteomic block; hence the information provided by the different blocks represent different attributes of abiological phenomenon.Fil: Rocha, Darío G. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina.Fil: González Montoro, Aldana. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía, Física y Computación; Argentina.Fil: González Montoro, Aldana. Consejo Nacional de Investigaciones Científicas y Técnicas. CIEM; Argentina.Fil: Prato, Laura. Universidad Nacional de Villa María; Argentina.Fil: Fernández, Elmer. Universidad Nacional de Villa María; Argentina.Otras Ciencias Naturales y Exacta
Detection and comparison of phenolic compounds in different extracts of black currant leaves by liquid chromatography coupled with high-resolution ESI-LTQ-Orbitrap MS and high-sensitivity ESI-Qtrap MS
No full textLiquid preparations such as tinctures and infusion derived from Ribes nigrum L. (black currant) leaves are widely used in Europe. Despite the various uses reported for the infusion and hydroalcoholic extracts of the leaves of this species, their chemical profile has not yet been defined. In the present study, the infusion, hydroalcholic and methanolic extracts prepared from R. nigrum leaves were analyzed. LC–MS analyses of these extracts allowed the characterization of 31 phenolic compounds mainly belonging to organic acids, flavonoids, catechins and its oligomers. Quantitative results proved that these preparations are a rich source of polyphenols and flavonoids and among them the infusion presented the highest polyphenol levels. A metabolomics approach was also used for the comparison and evaluation of the chemical composition of the different extracts obtained from R. nigrum leaves
Lc-esi/ltq-orbitrap-ms based metabolomics in evaluation of bitter taste of arbutus unedo honey
No full textStrawberry tree honey is a high-value honey from the Mediterranean area and it is charac-terised by a typical bitter taste. To possibly identify the secondary metabolites responsible for the bitter taste, the honey was fractionated on a C18 column and the individual fractions were subjected to sensory analysis and then analysed by liquid chromatography coupled with high-resolution tandem mass spectrometry in negative ion mode, using a mass spectrometer with an electrospray source coupled to a hybrid high resolution mass analyser (LC-ESI/LTQ-Orbitrap-MS). A chemometric model obtained by preliminary principal component analysis (PCA) of LC-ESI/LTQ-Orbitrap-MS data allowed the identification of the fractions that caused the perception of bitterness. Subsequently, a partial least squares (PLS) regression model was built. The studies carried out with multivariate analysis showed that unedone (2-(1,2-dihydroxypropyl)-4,4,8-trimethyl-1-oxaspiro [2.5] oct-7-en-6-one) can be considered responsible for the bitter taste of strawberry tree honey. Confirmation of the bitter taste of unedone was obtained by sensory evaluation of a pure standard, allowing it to be added to the list of natural compounds responsible for giving the sensation of bitterness to humans
Effetti di una sostanza ad azione anti-tiroidea,l'1- metil-2 -mercapto-imidazolo(tapazolo) sulla iodazione e la biosintesi delle iodoproteine tiroidee di ratto
No full textApócrifos de la memoria del Siglo XIX en cuba: disquisiciones sobre las ideas estéticas de Rafael Montoro
No full textThis research delves into the philosophical considerations of Rafael Calixto Montoro y Valdés, a Cuban intellectual with a neo-Hegelian formation in Spain. Known as the most important autonomist of 19th-century Cuba, he is also regarded by some authors as the Cuban most closely aligned with Hegelian thought. The research is structured, first, around a brief review of the philosophical context in which Montoro's intelectual production was greatest (1868-1878, Spain). It then examines his reflections on realism and idealism in Spanish dramatic art, and finally, the hierarchy of the arts he proposes—always taking into account his most significant philosophical reference, Friedrich Hegel.
Esta investigación permite profundizar en las consideraciones filosóficas de Rafael Calixto Montoro y Valdés, cubano de formación neohegeliana en España. Conocido como el más importante autonomista del siglo XIX en Cuba, es también entendido por algunos autores como el cubano con más filiación hegeliana. La investigación está encaminada, primero, a una revisión breve del contexto filosófico en el que la producciónintelectual de Montoro es mayor (1868-1878, España). Luego, se explicarán sus consideraciones sobre realismo e idealismo en el arte dramático en España. Por último, la jerarquización de las artes que propone. Siempre teniendo en cuenta su referente filosófico más importante, Friedrich Hegel.
 
Lc-esi/ltqorbitrap/ms metabolomic analysis of fennel waste (Foeniculum vulgare mill.) as a byproduct rich in bioactive compounds
No full textFood industries produce a high amount of waste every year. These wastes represent a source of bioactive compounds to be used to produce cosmetic and nutraceutical products. In this study, the possibility to retrain food waste as a potential source of bioactive metabolites is evaluated. In particular, metabolite profiles of different parts (bulb, leaves, stems and little stems) of fennel waste were investigated by liquid chromatography coupled with mass spectrometry (LC-ESI/LTQ Orbitrap MS). To discriminate the different plant parts, a Multivariate Data Analysis approach was developed. Metabolomic analysis allowed the identification of different metabolites mainly belonging to hydroxycinnamic acid derivatives, flavonoid glycosides, flavonoid aglycons, phenolic acids, iridoid derivatives and lignans. The identification of compounds was based on retention times, accurate mass measurements, MS/MS data, exploration on specific metabolites database and comparison with data reported in the literature for F. vulgare. Moreover, the presence of different oxylipins was relieved; these metabolites for the first time were identified in fennel. Most of the metabolites identified in F. vulgare possess anti-inflammatory, antioxidant and/or immunomodulatory properties. Considering that polyphenols are described to possess antioxidant activity, spectrophotometric tests were performed to evaluate the antioxidant activity of each part of the fennel
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