126 research outputs found
Galleri Format Malmö. Boksamtal. Release of Semester by Helga Härenstam and Collecting I by Anna Strand, and conversation with Thomas Millroth, art historian, critic, curator, author. Both books are published by Sailor Press and designed by Matilda Plöjel
No full text21/5. 22. Galleri Format. Boksläpp för Semester av Helga Härenstam och Collecting I, av Anna Strand samt i samband med detta, ett publikt samtal om böckerna tillsammans med Thomas Millroth. Semester (Text och fotografi, Helga Härenstam) kom ut 2021 på förlaget Sailor Press (se: https://gup.ub.gu.se/publications/show/312642) . Semester har även tidigare visats som bok (och utställning) på Gathenhielmska villan i Göteborg samt på Godisfabriken (On Strange Tides/ GIBCA extended.) Boken mottog också Svensk bokkonst pris och har i samband med detta under 2022 ställts ut på Kungliga biblioteket, Stockholm och andra platser i Sverige och internationellt. Semester var även under 2022 del av utställningen ” Publicerad – en utställning om den fotografiska boken” på Alingsås Kulturhus: https://www.alingsaskulturhus.se/att-gora/publicerad-en-utstallning-om-den-fotografiska-boken Ett samarbete med Centrum för fotografi och Fotoförfattarna inom Svenska Fotografers Förbund som turnerar runt på bibliotek i Västra Götaland. Semester har omskrivits bland annat i Fotografisk tidskrift samt: https://www.verktidskrift.se/bilder-av-de-narmaste-mattias-lundblad Och http://howsoftthisprisonis.blogspot.com/2022/02/semester-helga-harenstam-sailor-press.html Semester har under 2022 presenterats i samband med artist talks/bokmässor mm på bland annat Fotobok GBG, Fotoboksfestivalen Stockholm och Polycopies i Paris, Landskrona foto
Virus infections: lessons from pancreas histology
No full textType 1 diabetes mellitus is a chronic autoimmune disease resulting from the progressive immune-mediated destruction of pancreatic beta cells in genetically susceptible individuals, with the likely contribution of environmental factors, among which viruses have been extensively studied. The pathologic hallmark of the disease is insulitis-a process characterized by islet infiltration of immunocompetent cells that has been well characterized in animal models of islet autoimmunity, and to a lesser extent, in humans. Insulitis characterization has provided valuable information to gain insights into the disease pathogenesis. We review the recent literature on the viral contribution to beta-cell destruction and dysfunction in type 1 diabetes, with particular reference to the pathology of the pancreatic islet in humans and in animal models of the disease
Women with severe mutations in the gene 21α-hydroxylase do not express the characteristics phenotype after precocius diagnosis and treatment
No full textP l a n r i t n i n g e n – en källa för information och mystik [Elektronisk resurs]
No full textGalleri Silk bjöd in sju konstnärer till utställningen Planlösning (9 april–16 maj 2021) vilka fick i uppdrag att ”tolka och gestalta varsitt rum”. Jag blev tilldelad hallen. Hallen är navet till lägenheten. Genom ytterdörren når vi hallen, som därefter öppnar upp till resten av lägenhetens rum. Texten jag skrev handlar om vad kan en planritning och en planlösning kan berätta. ”Ritningen är ett dokument. Se framför dig en pappersrulle utrullad över bordet. Lite som en karta. En hel värld öppnar sig. Ett hemligt ark där varje streck har mening. Tänk in doften av det nyss kopierade handritade dokumentet och känslan av papperskvaliteten…
Homologous HSV1 and alpha-synuclein peptides stimulate a T cell response in Parkinson's disease
No full textModeled microgravity alters basal and insulin-mediated metabolic activity of normal and neoplastic cells
No full textEffects of High Glucose Concentrations on PC12 Cells: Possible Implications on Neurodegeneration
No full textHyperglycemia, which arises in type 1 or 2 diabetes, leads to different complications, such as macrovascular disease, nephropathy, retinopathy, and neuropathy. In addition, different cognitive variations are associated with type 1 diabetes. Long-term changes in glucose metabolism might induce effects on the central nervous system (CNS) such as reduced mental performance and loss of consciousness, which could be implicated in neurotoxicity. The direct impact of hyperglycemia and elevated glucose concentrations on neuronal cells remains to be fully elucidated, primarily due to the multifaceted mechanisms underlying glucose neurotoxicity, including apoptosis, oxidative stress, and alterations in signaling cascades. The multifaceted mechanisms further complicate the study of the relationship between diabetes and neurodegeneration. Research in this field is continually advancing, with the aim of investigating these eventual connections and developing more effective preventive and therapeutic strategies. The present study aims to assess the damage induced by different glucose concentrations (from 25 to 150 mM) in a neuronal model, such as PC12 cells, rat pheochromocytoma cells. In glucose-exposed PC12 cells, we have tested oxidative stress, apoptosis, and cell migration by (a) viability screening, (b) intracellular levels of anion superoxide (O2-), (c) extracellular levels of MDA and nitrites, (d) apoptosis, and (e) the wound healing assay. By the cell viability assay, it has emerged that glucose (25-150 mM) showed a stronger effect at the highest concentrations (100 and 150 mM). The increase in MDA and O2- levels was determined in PC12 cells treated with high glucose concentrations (6.5-8.8 fold for MDA). High concentrations (100 and 150 mM) significantly reduced the expression of full-length caspase-3 (2.8-fold and 4.2-fold decrease at 24 and 72 h) and caspase-9 (3.4-fold and 2.8-fold decrease at 24 h and 5-fold decrease at 72 h) compared with control conditions. Finally, the wound healing assay showed different scenarios during the several time points. Indeed, the wound closure rate was reduced in a dose-dependent manner (24 h: control 18%, G 50 mM 9%, 100 and 150 mM 8%; 48 h: control 26%, G 50 mM 20%, G 100 mM 13%, 150 mM 11%), following the treatment with three concentrations considered (50, 100, 150 mM). The results obtained in these experimental conditions highlight that glucose, at high concentrations, induced cell damage and corroborate the hypothesis that it could be involved in neurodegenerative diseases
Space flight affects motility and cytoskeletal structures in human monocyte cell line J-111
No full text
- …
