1,721,003 research outputs found
Angiolymphoid hyperplasia with eosinophilia treated with isotretinoin
No full textA 36-year-old white female was admitted to our Department. The diagnosis of angiolymphoid hyperplasia with eosinophilia (ALHE)was made. A surgical excision led to a fl are up of the lesions after 4 months. The lesions were treated with electrodessica-tion. After 5 months new angiomatoid lesions appeared. Isotretinoin (0.5 mg/kg/day) for 10 months led to a re-gression of the nodules which decreased in size, remain-ing stable without new lesions to date. During 2 years of follow-up no signi fi cant changes of this clinical picture have been observed We present this case to underline how isotretinoin could be a good alternative to stabilize the disease for its antiangiogenetic properties in patients who present recurrence of the disease. Moreover, in our case, with-drawal of isotretinoin did not accompany a flare up of the disease
CHURG-STRAUSS AND MONTELUKAST
No full textChurg-Strauss syndrome (CSS) is a systemic small vessel vasculitis involving lungs, skin, heart, gastrointestinal tract and peripheral nerves. We report the case of a 36-year-old woman with a necrotic lesion on the left foot of two months duration, associated with hypereosinophilia, patchy lung infiltrates, cardiac damage and a mononeuritis. The personal history was remarkable only for an asthma, treated with Montelukast, a leukotriene receptor antagonist (LRA). Clinical symptoms, laboratory exams and instrumental examinations led us to the diagnosis of CSS. In recent years several studies have reported the possible relationship between use of leukotriene receptor antagonist (LRA) and CSS expression. We report this case to underline the possible relationship between LRA and CSS and its etiopathogenetic mechanism
“Xeroderma pigmentoso: valutazione del comportamento biologico ‘benigno’ di neoplasie cutanee ‘maligne’ osservate in una paziente.
No full text
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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