11 research outputs found
Anomalous between-laboratory variability in a collaborative study of carcinoembryonic antigen immunoassay [letter]
No full textLarge liquid scintillator trackers for neutrino experiments
No full textResults are given on tests of large particle trackers for the detection of neutrino interactions in long-baseline experiments. Module prototypes have been assembled using TiO2-doped polycarbonate panels. These were subdivided into cells of ∼1 cm2 cross-section and 6 m length, filled with liquid scintillator. A wavelength-shifting fibre inserted into each cell captured a part of the scintillation light emitted when a cell was traversed by an ionizing particle. Two different fibre-readout systems have been tested: an optoelectronic chain comprising an image intensifier and an electron-bombarded CCD (EBCCD); and a hybrid photodiode (HPD). New, low-cost liquid scintillators have been investigated for applications in large underground detectors. Testbeam studies have been performed using a commercially available liquid scintillator. The number of detected photoelectrons for minimum-ionizing particles crossing a module at different distances from the fibre readout end was 6-12 with the EBCCD chain and a mirror at the non-readout end; 4-10 with the HPD and no mirror. The light-attenuation lengths in the fibres were ∼9.4 m with the EBCCD and ∼6.4 m with the HPD. The detector response to electron showers has also been measured. After ten radiation lengths of lead, the transverse position of the incoming electron was determined with a precision of a few millimetres for electrons of 4 GeV, and with a precision of 1.5-2.0 cm for electrons of 1 GeV. © 2002 Elsevier Science B.V. All rights reserved.0SCOPUS: ar.jinfo:eu-repo/semantics/publishe
Gastric peroral endoscopic myotomy for management of refractory gastroparesis in patients with gastric neurostimulator devices: a multicenter retrospective case control study
No full textBackground and Aims
Gastric neurostimulation (GNS) and gastric peroral myotomy (G-POEM), therapies for refractory gastroparesis, are associated with suboptimal outcomes. We studied the role of G-POEM as a salvage therapy in patients with refractory symptoms after GNS implantation.
Methods
This was a multicenter, retrospective, matched case-control study. Consecutive patients with a GNS device and who underwent G-POEM as a salvage therapy for clinical failure (cases) and patients without GNS implantation and who underwent G-POEM for refractory gastroparesis (control) between October 2018 and August 2021 were included. The primary outcome was clinical success after G-POEM.
Results
A total of 123 patients (mean age 45.7 ± 14.7 years; 88 female subjects [72%]) underwent G-POEM therapy during the study: 41 cases and 82 controls. Clinical success was achieved in 66% in the case group and 65% in the control group (P = .311), during a median total clinical follow-up time of 11.8 (interquartile range, 2.4-6.3) months. In the case group, the mean Gastroparesis Cardinal Symptom Index score decreased from 2.8 ± 1.8 to 1.5 ± 1.9 (P = .024), and gastric retention at 4 hours improved from 45% ± 25.8% to 16.6% ± 13.1% (P = .06). The mean delta improvement in the subscales of nausea/vomiting (1.3 ± .6 vs .9 ± 1.1, P = .044) and bloating (1.6 ± 1.3 vs 1.2 ± 1.4, P = .041) were significantly higher in cases than in controls.
Conclusions
Among patients with refractory symptoms after GNS, G-POEM can be a reasonable salvage therapy to provide further symptomatic relief with evidence of a potential additive effect of both G-POEM and GNS.
Abbreviations
Gastric Peroral Endoscopic Myotomy for Management of Refractory Gastroparesis in Patients with Gastric Neurostimulator Devices: A Multicenter Retrospective Case Control Study
No full textBACKGROUND AND AIMS: Gastric neurostimulation (GNS) and gastric peroral myotomy (G-POEM), therapies for refractory gastroparesis, are associated with suboptimal outcomes. We studied the role of G-POEM as a salvage therapy in patients with refractory symptoms after GNS implantation.
METHODS: This was a multicenter, retrospective, matched-case control study. Consecutive patients with GNS device and underwent G-POEM as a salvage therapy for clinical failure (cases) and patients without GNS implantation and underwent G-POEM for refractory gastroparesis (control) between 10-2018 and 08-2021 were included. The primary outcome was clinical success after G-POEM.
RESULTS: A total of 123 patients (mean age 45.7 ± 14.7 years; 88 females [72%]) underwent G-POEM therapy during the duration of the study: 41 cases and 82 controls. Clinical success was achieved in 66% in the case group and 65% in the control, (P=0.311), during a median total clinical follow-up time of 11.8 (IQR: 2.4-6.3) months. In the case group, the mean Gastroparesis Cardinal Symptom Index (GCSI) decreased from 2.8 ± 1.8 to 1.5 ± 1.9, (P=0.024), and gastric retention at 4 hours improved from 45% ± 25.8 to 16.6% ± 13.1, (P=0.06). The mean delta improvement in the subscales of nausea/vomiting (1.3 ± 0.6 vs. 0.9 ± 1.1; P=0.044) and bloating (1.6 ± 1.3 vs. 1.2 ± 1.4; P=0.041) were significantly higher in cases than in controls.
CONCLUSIONS: Among patients with refractory symptoms after GNS, G-POEM can be a reasonable salvage therapy to provide further symptomatic relief with evidence of a potential additive effect of both G-POEM and GNS
Measurement of the t(t)over-bar production cross section in p(p)over-bar collisions at root s=1.8 TeV
No full textWe present a measurement of the t (t) over bar production cross section in p (p) over bar collisions at root s = 1.8 TeV using an integrated luminosity of 109 pb(-1) collected with the Collider Detector at Fermilab. The measurement uses t (t) over bar decays into final states which contain one or two high transverse momentum leptons and multiple jets, and final states which contain only jets. Using acceptances appropriate for atop quark mass of 175 GeV/c(2), we find sigma(ii) = 7.6(-1.5)(+1.8) pg
Proceedings of the 45th Annual Meeting of the Southern Soybean Disease Workers (March 7-8, 2018, Pensacola Beach, Florida)
No full textContents
List of SSDW Officers
Agenda for March 7-8, 2018
Abstracts for contributed/presented papers
Retrospective analyses regarding the impact of soybean diseases in the USA .TW Allen, PD Esker, and CA Bradley
Diaporthe (Phomopsis) species on soybean: current status in the United States. Febina Mathew, Kristina Petrovic, Lisa Castlebury, Tom Allen, Gary Bergstrom, John Bonkowski, Carl Bradley, James Buck, Emmanuel Byamukama, Martin Chilvers, Anne Dorrance, Nicholas Dufault, Loren Giesler, Nancy Gregory, Heather Kelly, Nathan Kleczewski, Trey Price, Dean Malvick, Sam Markell, Daren Mueller, Damon Smith, Terry Spurlock, Kiersten Wise, and Marina Johnson
New insights into the genetic underpinnings of pathogenesis in Cercospora cf. flagellaris. Burt Bluhm, Ahmad Fakhoury, Alex Zaccaron, and Kona Swift
Evaluation of spore traps and molecular tools for a fungicide decision model for frogeye leaf spot. HM Kelly and B Lin
Site-specific management strategies against multiple nematode species in soybean. C Overstreet, EC McGawley, DM Xavier-Mis, and JS Rezende
Field efficacy of two new seed-applied biological agents for suppression of root-knot nematodes in soybean. Travis R Faske, Michael Emerson, and Katherine Hurd
Evaluation of 418 soybean plant introductions with reported resistance to soybean cyst nematode for reniform nematode resistance. Robert T Robbins and Devany Crippen
Studies on Soybean vein necrosis virus in Alabama. EJ Sikora, D Delaney, A Jacobson, K Conner, A Chitturi, and J Kemble
Using unmanned aerial vehicle (UAV) photograph analysis to generate corroborating data in small plot soybean fungicide efficacy trials. P Price, MA Purvis, and P Washam
Building a foundation for cultivar and fungicide selection decisions in soybean. HM Kelly
Results from the 2017 Mississippi State University target spot fungicide efficacy program. TW Allen and TH Wilkerson
Relating temperature and relative humidity in commercial warehouses to decline in vigor of soybean seed stored for late plantings in Arkansas. JC Rupe, JA Lee, A Palmer, RT Holland, J Robinson, RD Cartwright, and G Atungulu
Seed treatment for sudden death syndrome management in soybean. Yuba R Kandel, Carl A Bradley, Martin I Chilvers, Febina M Mathew, Albert U Tenuta, Damon L Smith, Kiersten A Wise, and Daren S Mueller
Evaluation of screening methods for soil-borne diseases of soybean (Glycine max) in west Tennessee. R Guyer, E Zuchelli, and H Kelly
Abstracts for student papers
An update on taproot decline in Arkansas. J Bailey, AC Tolbert, B Boney, and TN Spurlock
Taproot decline of soybean is caused by an undescribed species in the Genus Xylaria. T Garcia-Aroca, P Price, M Tomaso-Peterson, T Spurlock, TR Faske, B Bluhm, K Conner, EJ Sikora, R Guyer, H Kelly, TW Allen, and VP Doyle
Assessing pathogenicity and virulence of Xylaria sp. isolates from Mississippi soybean. H Renfroe, T Wilkerson, T Allen, and M Tomaso-Peterson
Effects of mycovirus infection on virulence of Rhizoctonia solani in soybean. TJ Stetina, CS Rothrock, and TN Spurlock
Is the emergence of Soybean vein necrosis virus linked to the re-emergence of Tobacco streak virus? C Zambrana-Echevarría, CL Groves, TL German, and DL Smith
Is soybean vein necrosis a threat to soybean production? NR Anderson, MD Irizarry, CA Bloomingdale, DL Smith, CA Bradley, DP Delaney, NM Kleczewski, EJ Sikora, DS Mueller, and KA Wise
Yield prediction in soybean fields using satellite imagery. B Boney and TN Spurlock
Elucidating the race population structure of Cercospora sojina through genotypic patterns. Wagner Fagundes, Marcio Zaccaron, Alex Zaccaron, and Burton H Bluhm
Impact of foliar fungicide applications in soybean fields across aggregated distributions of disease. M Patterson, AC Tolbert, and TN Spurlock
Abstract for presented poster
Assessing the genetic diversity of Cercospora spp. associated with Cercospora leaf blight of soybean in North America. Kona Swift and Burt Bluhm
Southern United States soybean disease loss estimates for 2017. TW Allen, K Bissonnette, CA Bradley, JP Damicone, NS Dufault, TR Faske, CA Hollier, T Isakeit, RC Kemerait, NM Kleczewski, HL Mehl, JD Mueller, C Overstreet, PP Price, EJ Sikora, TN Spurlock, L Thiessen, and H Young
Proceedings of the Southern Soybean Disease Workers area published annually by the Southern Soybean Disease Workers.
Text, references, figures, and tables are reproduced as they were submitted by authors. The opinions expressed by the participants at this conference are their own and do not necessarily represent those of the Southern Soybean Disease Workers.
Mention of a trademark or proprietary products in this publication does not constitute a guarantee, warranty, or endorsement of that product by the Southern Soybean Disease Workers.
Appreciation is given to the staff at the University of Kentucky Research & Education Center, Princeton, KY, for their assistance in assembling these Proceedings
Proceedings of the 51st Annual Meeting, Southern Soybean Disease Workers (March 6-7, 2024, Pensacola Beach, Florida)
No full textSuccess in Extension (moderator: Kiersten Wise)
Institutional currency: What is important at your university? Loren Giesler
Success (and challenges) in extension in the Mid-West, Daren Mueller
Success in extension in the Mid-Atlantic, Alyssa Koehler
Success (and failures) in xxtension in the Southeast, Ed Sikora
Success in extension in the Mid-South, Travis Faske
Student Competition (moderator: Ian Small)
Hiding in plain sight: Disentangling the biology of Cercospora species associated with Cercospora leaf blight of soybean, Ernesto da Silva, J. Searight, J. Richards, P. Price, and V. Doyle
Using spore traps to decipher the epidemiology of Cercospora leaf blight in the mid-south, Stephanie K. Ramos, N. Galagedara, V. P. Doyle, T. W. Allen, T. N. Spurlock, P. P. Price, B. Padget, L. Coghill, and S. Thomas-Sharma
Using environmental variables for the development of logistic regressions to predict frogeye leaf spot in soybean in the United States, José F. González-Acuña, M. D. Bish, C. A. Bradley, T. R. Faske J. M. Scherer, H. M. Young-Kelly, D. K. Malvick, D. Mangel, S. G. Markell, D. S. Mueller, P. P. Price, D. L. Smith, D. E. P. Telenko, and R. W. Webster
Spatial distribution of resistance of Corynespora cassiicola in Arkansas to quinone outside inhibitor and succinate dehydrogenase inhibitor fungicides based on frequencies of key target-site alterations, Rafael Zaia, T. R. Faske, Jeremy Ross, A. Rojas, and T. Spurlock
Use of UAV tools to quantify disease, Elias Zuchelli and H. Kelly
Evaluation of resistance in soybean varieties to reniform nematode (Rotylenchulus reniformis) in Louisiana fields, Lucy Kiarie, P. P. Price, and T. Watson
Utilization of qRT-PCR to Quantify Macrophomina phaseolina population in 2023 Soybean OVT, Jon K. Corser, S. Tripathi, T. Allen, S. Ahn, N. Tadlock, and T. H. Wilkerson
Screening soybean accessions for resistance to Diaporthe longicolla as a stem and seed pathogen, B. M. Sureshbabu, K. Mohan, N. Rafi, A. Gillen, J. R. Smith, and Febina M. Mathew
Contributed Papers (moderator: Terry Spurlock)
Severity of charcoal rot disease in soybean genotypes inoculated with Macrophomina phaseolina isolates differed among growth environments, Alemu Mengistu, Q. Read, C. Little, and H. Kelly
Surveying Calonectria ilicicola isolates from red crown rot diseased soybean in Illinois, Steven J. Clough, T. Herman, and N. McCoppin
Employing seed treatment as a soybean red crown rot management tool, Dale Ireland, and R. Kuznia
Seed treatment and environmental risk factor evaluation for sudden death syndrome of soybean, Nabin K. Dangal, E. M. Ernat, M. Chilvers, R. Hamilton, and D. S. Mueller
Relationship of soybean seed infection to seed composition, John Rupe, A. Rojas, R. Adams, R. Holland, and S. Segalin
The origin, evolution, and chemical ecology of Xylaria necrophora, the causal agent of taproot decline, Vinson P. Doyle, T. Garcia-Aroca, J. Solórzano, J. K. R., Fabrizio Donnarumma, R. Kartika, T. Allen, T. Spurlock, and P. Price
Can targeting fungicide applications to spore peaks improve the efficacy and economics of Cercospora leaf blight management? Sara Thomas-Sharma, S. Ramos, N. N. Galagedara, J. Amie, V. P. Doyle, T. Price, B. Padgett, T. Allen, T. Spurlock, and L. Connor
The potential of managing soybean fungal diseases through the application of double stranded RNAs. Y. Raruang, S. Marahatta, V. Khambhati, and Zhi-Yuan Chen
Missouri on-farm strip trials: 5-year summary of fungicide applications to R3 soybean, Mandy Bish, J. Calhoun, K. Bissonnette, and J. Lory
Using data generated from on-farm and experiment station trials to help farmers manage soybean diseases, G. Boyd Padgett, T. Price, and D. Moseley
Fungicide use in soybean: should we change our strategy? Terry Spurlock, R. Zaia, R. Hoyle, A. Tolbert, S. Pennington, K. Knight, and J. Davis
Proceedings of the Southern Soybean Disease Workers are published annually by the Southern Soybean Disease Workers.
Text, references, figures, and tables are reproduced as they were submitted by authors. The opinions expressed by the participants at this conference are their own and do not necessarily represent those of the Southern Soybean Disease Workers.
Mention of a trademark or proprietary products in this publication does not constitute a guarantee, warranty, or endorsement of that product by the Southern Soybean Disease Workers
A Measurement of alpha-s from jet rates at the Z0 resonance
No full textWe have determined the strong coupling alpha(s) from measurements of jet rates in hadronic decays of Z0 bosons collected by the SLD experiment at SLAC. Using six collinear and infrared safe jet algorithms we compared our data with the predictions of QCD calculated up to second order in perturbation theory, and also with resummed calculations. We find alpha(s)(M(Z)2)=0.118+/-0.002(stat)+/-0.003(syst) +/-0.010 (theory), where the dominant uncertainty is from uncalculated higher order contributions
Setting minimum standards for training in EUS and ERCP: Results from a prospective multicenter study evaluating learning curves and competence among advanced endoscopy trainees (AETS).
No full textBackground: Despite the dramatic increase in advanced endoscopy training programs (AETPs), there is no fixed mandatory curriculum and minimal standards as to what constitutes a “high quality” AETP has not been defined. Understanding the mean number of procedures required to achieve competence in all aspects of EUS and ERCP would help structure AETPs. Aims: To define the mean number of procedures required by an “average” AET to achieve competence in technical and cognitive EUS and ERCP tasks. Methods: ASGE recognized AETPs were invited and AETs were graded on every 5th EUS and ERCP exam after completion of 25 hands-on EUS and ERCP exams using the validated EUS and ERCP Skills Assessment Tool (TEESAT). Grading for each skill was done using a 4-point scoring system. A comprehensive data collection and reporting system was used to create learning curves (LCs) using cumulative sum (CUSUM) analysis for overall and technical and cognitive components of EUS and ERCP and shared with AETs and trainers quarterly. Acceptable and unacceptable failures rates were set a priori. In order to generate aggregate CUSUM LCs across AETs, we used generalized linear mixed effects models with a random intercept for each AET and an AR1 covariance structure. This allowed us to use data from all AETs to estimate the average learning experience for trainees with 95% CIs. We then fit a spline to the modeled estimates with knots at 40 and 80 evaluations to smooth the results and estimate the mean number of procedures needed to achieve competence. Results: Of the 62 AETPs invited, 37 AETs from 32 AETPs participated in this study; 24 AETs were included in the final analysis. Prior to AETP, 52% reported hands-on EUS (median 20 cases) and 68% hands-on ERCP (median 50 cases) experience prior to AETP. At the end of training, median number of EUS and ERCPs performed/AET was 400 (range 200-750) and 361 (250-650), respectively. Overall, 2616 exams were graded (EUS: 1277, ERCP-biliary 1143, pancreatic 196). Majority of graded EUS exams were performed for pancreatobiliary indications (69.9%) and ERCP exams for ASGE biliary grade of difficulty 1 (72.1%). Table 1 highlights the substantial variability in EUS and ERCP learning curves. The majority of trainees achieved overall technical (EUS: 91.7%; ERCP: 73.9%) and cognitive (EUS: 91.7%, ERCP: 95.7%) competence at the end of training. Table 1 and Figure highlight the number of procedures required by an average AET to achieve competence in all aspects of EUS and ERCP. Conclusions: The results of this study confirm the substantial variability in achieving competence in EUS and ERCP. The thresholds provided for an average AET to achieve competence in EUS (w225 cases) and ERCP (w250) may be used by ASGE and AETPs in establishing the minimal standards for case volume exposure for AETs during their training
