1,721,832 research outputs found
Denaturation of biological macromolecules :new programs for the deconvolution of DSC measurements
G. Russo, J. Anastassopoulou, G Barone Eds
Denaturation of Biological Macromolecules: New Programs for the Deconvolution of DSC Measurements
Denaturation of biological macromolecules :new programs for the deconvolution of DSC measurements
G. Russo, J. Anastassopoulou, G Barone Eds
Peptide-Peptide Interactions in Water and Concentrated Urea Solutions. Review
A review is presented on some recent developments in the
thermodynamics of aqueous solutions of organic substances, that can be
considered as models of the repeating units of naturally occurring
polypeptides and proteins. The attention is firstly focused on the
solute-solvent interactions as basis to understand some aspects of the
solute-solute interactions. The solvent in fact, especially in dilute
solutions, seems to take active part in these interactions. All these
poorly specific interactions, as are repeated for each aminoacid
residue, must be considered in the conformational treatments of the
stability of proteins. Preliminary interesting data are also reported,
concerning model peptide-model peptide and other interactions in
concentrated aqueous solution of urea, that is a usual denaturing
medium for proteins and biopolymers. The unexpected and stimulating
results suggest that, in this solvent, the hydrophilic interactions
are screened, probably because polar groups are preferentially
solvated by urea. Moreover the highly polar urea-water mixtures seem
still to exert a kind of "lipophobic" effect against the alkylic
chains of the considered solutes
Methane Hydrates: Resource or Climatic Threat? Stability of natural gases Hydrates and exploitation Perspectives
Methane Hydrates: Energy Resources or Climatic Threat? Stability of Natural Gas and Exploitation Perspectives
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