8,577 research outputs found
TACC3-ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation
No full textThe interaction between TACC3 (transforming acidic coiled coil protein 3) and the microtubule polymerase ch-TOG (colonic, hepatic tumor overexpressed gene) is evolutionarily conserved. Loading of TACC3–ch-TOG onto spindle microtubules requires the phosphorylation of TACC3 by Aurora-A kinase and the subsequent interaction of TACC3 with clathrin to form a microtubule binding surface. Whether there is a pool of TACC3–ch-TOG that is independent of clathrin in human cells, and what is the function of this pool, are open questions. Here, we report that TACC3 is recruited to the plus-ends of microtubules by its association with ch-TOG and that this pool is independent of phosphorylation and binding to clathrin. The plus-end binding of TACC3–ch-TOG persists in interphase and we propose that one cellular function of TACC3–ch-TOG is to modulate cell migration. We also describe the distinct subcellular pools of TACC3, ch-TOG and clathrin. TACC3 is often described as a centrosomal protein, but we show that there is no significant population of TACC3 at centrosomes. The delineation of distinct protein pools reveals a simplified view of how these proteins are organized and controlled by post-translational modification
Le premier du mois : chanson créée par Madame Amiati à la Scala [illustration G. Fuchs (Gustave Fuchs (1856-19..)]
No full textLe premier du mois : chanson créée par Madame Amiati à la Scala ; illustration signée G. Fuchs (Fuchs série portrait Amiati) [Gustave Fuchs (1856-19..)] ; paroles Anna David ; musique Ch. Pourny ; A. Fouquet éditeur, 9 boulevard St-Denis [intérieur : mentions artiste identique ; prénom complet pour Pourny [Charles Pourny] ; sans date, sans ©, cotage AF251, datation par cotage 1888, (Devriès et Lesure) ; verso catalogue éditeur (medihal-00717125)]. Incipit : "Un jour Jacques, pimpant, coquet". Une attestation avec une illustration identique (colorisée) est en ligne sur Illustrated Sheet Music (http://www.imagesmusicales.be/search/title/Premier+du+mois/ShowData/8/Submit/)
Ma première connaissance : chansonnette créée par Debailleul au XIXe siècle [illustration G. Fuchs (Gustave Fuchs (1856-19..)]
No full textMa première connaissance : chansonnette créée par Debailleul au XIXe siècle ; dédicace : "A Monsieur Léry" ; [illustration signée] Gustave Fuchs ; paroles Villemer [Gaston Villemer] et Soubise [Camille Soubise] ; musique Ch. Pourny [Charles Pourny] ; Maison L. Vieillot, Louis Labbé successeur [Ludovic Vieillot (1820-1874)] ; [intérieur : dédicace et mention artiste id. ; cotage LV6382, datation par cotage 1880 (Devriès et Lesure) ; recto vierge] ; incipit : "C'était une blonde modiste"
Le premier du mois : chanson créée par Madame Amiati à la Scala [illustration Gustave Fuchs]
No full textLe premier du mois : chanson créée par Madame Amiati à la Scala ; paroles Anna David ; musique Ch. Pourny ; illustration signée Gustave Fuchs (Fuchs série portrait Amiati) ; A. Fouquet éditeur, 9 boulevard St-Denis [intérieur : mentions artiste identique ; prénom complet pour Pourny [Charles Pourny] ; sans date, sans ©, cotage AF251, datation par cotage 1888, (Devriès et Lesure) ; verso catalogue éditeur (medihal-00717125)]. Incipit : "Un jour Jacques, pimpant, coquet". Une attestation avec une illustration identique (colorisée) est en ligne sur Illustrated Sheet Music (http://www.imagesmusicales.be/search/title/Premier+du+mois/ShowData/8/Submit/)
Ma première connaissance : chansonnette créée par Debailleul au XIXe siècle [illustration Gustave Fuchs]
No full textMa première connaissance : chansonnette créée par Debailleul au XIXe siècle ; dédicace : "A Monsieur Léry" ; [illustration signée] Gustave Fuchs ; paroles Villemer [Gaston Villemer] et Soubise [Camille Soubise] ; musique Ch. Pourny [Charles Pourny] ; Maison L. Vieillot, Louis Labbé successeur [Ludovic Vieillot (1820-1874)] ; [intérieur : dédicace et mention artiste id. ; cotage LV6382, datation par cotage 1880 (Devriès et Lesure) ; recto vierge] ; incipit : "C'était une blonde modiste"
Les diminutifs basques avec ch
No full textSe presentan formaciones similares a los diminutivos vascos con "ch" en España y América latina. Se dan ejemplosThe author introduces similar formations to the Basque diminutive "ch" in Spain and Latin America. Examples are provide
Abb. 2 in Elophos caelibaria senilaria (Fuchs, 1901) und spurcaria (de la Harpe, 1853) in der Schweiz und Vorarlberg, Österreich (Lepidoptera: Geometridae).
No full textAbb. 2. Männchen und kurzflügelige Weibchen von Elophos caelibaria senilaria (1–6) und spurcaria (7–12). 1–2: CH Brisen-Haldigrat (NW), 2 200 m, 5.8.1975 und 29.7.1984. 3–4: CH Pilatus-Kulm (NW / OW), 2 050 m, 11.7.1979 und 21.–31.7.1979. 5–6: D Aggenstein, Allgäu, 2 000 m, 22.6.1949 und A Sattelspitze, Nordtirol, 2 310 m, 9.8.1940. 7–8: CH Umbrailpass (GR), Nordseite, 2 450 m, 26.7.1990 und CH Zermatt (VS), Gornergrat, 3 000 m, 7.7.1976. 9–10: CH Zermatt (VS), Riffelsee, 2 700 m, 7.7.1976 (2). 11–12: A Timmelsjoch, Ötztal, 2 600 m, 14.7.1974 und CH Saas Fee (VS), 2 400 m, 21.–31.7.1956.Published as part of Rezbanyai-Reser, Ladislaus & Aistleitner, Eyjolf, 2013, Elophos caelibaria senilaria (Fuchs, 1901) und spurcaria (de la Harpe, 1853) in der Schweiz und Vorarlberg, Österreich (Lepidoptera: Geometridae)., pp. 129-134 in Entomo Helvetica 6 on page 131, DOI: 10.5169/seals-986049, http://zenodo.org/record/806027
COUPLING OF THE C-H STRETCH TO LARGE-AMPLITUDE TORSION AND INVERSION MOTIONS: COMPARISON OF CHCH, CHOH AND CHNH
No full textAuthor Institution: Department of Polymer Science and Department of Chemistry, The University of Akron; Department of Chemistry, The University of Akron, OH 44325In each of the title molecules, torsional and inversion tunneling occurs between six equivalent minima. Coupling of these degrees of freedom to the CH stretch occurs via variation of the C-H stretching force constants as a function of the torsional () and inversion () angles. Maps of the couplings have been computed at the MP2/6-311++G(3df,2p) level. Both the single bond CH stretch force constants and the bilinear couplings between CH bonds are presented as a function of and . Although the torsional barriers differ by more than a factor of 20, the torsion-inversion-vibration coupling patterns are very similar for CHNH and CHCH. On the other hand, the torsion-inversion-vibration coupling in the charged species CHOH is much weaker
The Impact of Public Health Policy: The Case of Community Health Centers
No full textThe aim of this paper is to assess the impact of the Community Health Center (CHC) on health levels in the U.S. Using infant mortality as the underlying health indicator, a time series of large counties as the data set, and multivariate regression techniques, we investigate the extent to which the presence of a program in a county affects future mortality. We find that CHCs have negative and statistically significant impacts on white and black infant mortality rates.The centers have larger effects on black infant mortality than on white infant mortality. The reduction in the black infant mortality rate between 1970 and 1978 due to the CHC system amounts to one death per thousand live births or approximately 12 percent of the observed decline.This result is particularly striking in light of the well-known higher infant mortality rate of blacks. A reduction in the excess mortality rate of black babies has been dentfied as a goal of public health policy for a number of years. Our results suggest that community health centers have the potential to make a substantial contribution to the achievement of this goal.
Reply to the Ch. Lagrange’s note
No full textThe author answers to a Ch. Lagrange’s note who refutes his theory on the diurnal nutation.L’auteur répond à une note de Ch. Lagrange qui réfute sa théorie sur la nutation diurne
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