1,720,979 research outputs found
Role of computer-assisted analysis of the corneal endothelium in vitreoretinal surgery with intraocular silicone oil injection: a technical report
No full textThe innermost lining of the cornea consists of a single layer of cells called the endothelium. Despite its name, the endothelium of the cornea differs considerably from the vascular endothelium, both functionally and morphologically. The corneal endothelium plays a fundamental role in maintaining the transparency of the corneal membrane, as the result of both its function as a barrier against penetration of the aqueous humor in the parenchyma and its ability to remove water from the stroma (usually referred to as the endothelial "pump" function). Any abnormality in the corneal endothelium causes, first, the impairment of its function as a barrier and pump due to the loss of stromal anti-turgor mechanisms, followed by edema and possible development into keratopathy. The specular microscope is an instrument which makes it possible to see the endothelial "mosaic" in the reflected image of the posterior corneal surface. A large variety of clinical specular microscopes is presently available, both contact and non-contact, which allow, for easy and rapid photography of the corneal endothelium "in vivo". In the present case, we used a non-contact computerized specular microscope to analyze the corneal endothelium in a group of patients affected by retinal detachment who needed to undergo vitreoretinal surgery with immission of silicone oil into the vitreal chambe
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Photostimulation with subthreshold yellow micropulsed laser for chronic residual subfoveal rhegmatogenous retinal detachment after surgery
No full textPurpose
The aim of this pilot study, the first of this kind, was to evaluate the safety and efficacy of Subthreshold Yellow Micropulsed Laser (SML) to treat eleven patients with chronic residual subfoveal Retinal Detachment (RD) after surgery to repair Rhegmatogenous Retinal Detachment (RRD).
Methods
Eleven eyes with residual subfoveal RD after surgery, dating from eight to sixteen months before treatment have been evaluated. Evaluation included visual acuity, Amsler test, ophthalmoscopy, Autofluorescence (AF) and Spectral-Domain Optical Coherence Tomography (SD-OCT).
Results
After treatment we recorded improved visual acuity and Amsler test, disappearance of subfoveal detachment by ophthalmoscopy, reduced retinal pigment epithelial distress by AF and restored macular retinal profile without neuroretinal alterations by SD-OCT evaluation in nine eyes.
Conclusions
Photostimulation with SML, selective for the Retinal Pigment Epithelium (RPE), is proved to be painless, effective and safe. The possibility to reabsorb subretinal liquid by foveal and parafoveal RPE photostimulation, without neuroretinal damage, opens new prospects for the therapy of this pathology. If further studies confirm the results of the present pilot study, SML treatment can be considered the first and only non invasive option for chronic residual RD after retinal surgery to repair RRD
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Neonatal retinoblastoma
No full textPurpose: To identify patients with retinoblastoma diagnosed at the age of 1 month and describe their clinical features and treatment outcome.
Methods: A retrospective study of 715 cases of retinoblastoma diagnosed and treated at the Retinoblastoma Referral Center University of Siena between 1980 and 2018 has been performed.
Results: Thirty‐!ve patients diagnosed within the !rst month of life have been identi!ed. The majority of them had a bilateral form; among the unilateral ones some of them developed metachronous tumors in the fellow eye. Family history was positive in most of them. The follow‐up range was 1 to 37 years. Management included early enucleation, systemic chemotherapy, bridge chemotherapy followed by intraarterial chemotherapy and focal treatments. None of them developed metastatic disease or second tumors.
Conclusions: Family history prompted early diagnosis in most cases. However, early diagnosis does not always mean early stage of the disease and better prognosis
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Long-term effectiveness of lumboperitoneal flow-regulated shunt system for idiopathic intracranial hypertension
No full textAIM: The aim of the study was to assess the efficacy of lumboperitoneal flow-regulated shunt for the treatment of idiopathic intracranial hypertension (IIH).
METHODS: This was a retrospective study carried out on four patients with IIH, treated from January to December 2007 with lumboperitoneal flow-regulated shunt (OSV II Smart Valve Systems; Integra NeuroSciences). The mean follow-up period was 13 months.
RESULTS: The treatment was successful in alleviating symptoms in all cases and no patient required revisions.
CONCLUSIONS: In conclusion the placement of flow-regulated valves is a satisfactory treatment for those IIH patients who require surgical therapy
Subthreshold Micropulse Laser for Long-Lasting Submacular Fluid after Rhegmatogeous Retinal Detachment Surgery
No full textPurpose: To assess the safety and efficacy of subthreshold micropulse laser (SML) photo-stimulation in the management of persistent subfoveal fluid (PSF) after surgery for rhegmatogenous retinal detachment (RRD). Methods: In this pilot study, 11 eyes of 11 patients (8 men, 3 women) with long-lasting (12–18 months) PSF after surgery for RRD were evaluated before and after photostimulation with subthreshold micropulse yellow laser. Ophthalmic examination included best-corrected visual acuity (BCVA), Amsler grid test, ophthalmoscopy, autofluorescence (AF), and optical coherence tomography (OCT) with measurement of central point foveal thickness (CPFT). Primary outcome was subfoveal fluid resolution and secondary outcome was BCVA improvement. Results: The mean CPFT and BCVA were, respectively, 436.8 ± 28.8 μm and 0.25 ± 0.1 μm decimal equivalent (DE) before photostimulation and 278 ± 54.4 μm and 0.57 ± 0.2 μm DE after photostimulation, a statistically significant difference (P < 0.001). Nine (81.8%) eyes showed improved BCVA, disappearance of macular detachment on ophthalmoscopy, reduced retinal pigment epithelium distress on AF, and restored macular profile with no neuroretinal alterations on OCT scans. Conclusion: Although PSF after RRD surgery is often a self-limiting disease, our results suggest that SML photostimulation may be effective and safe in patients with clinically significant long-lasting PSF. Larger case–control studies are necessary to confirm these results
Peptidergic innervation of mesenteric lymphatics in guinea pigs: an immunocytochemical and pharmacological study.
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