504 research outputs found
"Dans Les Montagnes Suisses... ". Avec le Professeur Leszek Libera interviewé par Jarosław Ławski
Redakcja serii: Jarosław Ławski, Krzysztof KorotkichRedaktor tomu: Jarosław ŁawskiThe volume is a transcript of a conversation between Professor Jarosław Ławski and Professor Leszek Libera held in August 2022. Leszek Libera (born in 1948 in Racibórz) is a Professor Emeritus at the University of Zielona Góra; a historian of Polish literature, a translator from German, and a novelist. The fruit of his work, reading, and research are several books devoted to the works of Juliusz Słowacki (and, to a lesser extent, Adam Mickiewicz). For nearly twenty years he has been associated with the intellectual milieu of Zielona Góra; at the local university, he conducted master’s seminars and gave lectures on the history of literature. He is the author of numerous studies on the literature of Polish and German Romanticism, as well as monographs: Juliusz Słowacki’s Journey to the Holy Land from Naples, Poznań 1993; Romanticism and Folklore: The Works of Jacek Malczewski and Bolesław Leśmian, Poznań 1994; In Switzerland: A Study of Juliusz Słowacki, Kraków 2001; “Maria Stuart”: A Drama by Juliusz Słowacki, Zielona Góra 2003; Wounded Illusion: on Juliusz Słowacki’s “Balladyna” and Ludwig Tieck’s “Puss in Boots”, Zielona Góra 2007; Mickiewicz and Medicine: Romantic Sketches, Zielona Góra 2010; Gottfried August Bürger – Author of “Lenora”, Bialystok 2016. He has published his own translations, published as annotated editions: Ludwig Tieck’s Puss in Boots and The World in a Wrap, Zielona Gora 2007; Ludwig Tieck’s Prince Zerbino, or A Journey in Search of Good Taste. In a Sense, A Continuation of Puss in Boots. German Comedy in Six Scenes, Zielona Gora 2012, Ludwig Tieck’s Blonde Eckbert and Mountain Run, Białystok 2022. In 2021, he published a biography: Ludwig Tieck Called the King of Romanticism, Białystok 2021. He is the author of a trilogy Der Utopek. Roman, Dresden 2011, Buks Molenda. Roman, Dresden 2012, Utopek’s Testament, Dresden 2020, which was published in Polish in a translation by Sława Lisiecka.
Professor Leszek Libera has been repeatedly invited to give a “Lecture of Master” at the Faculty of Philology at the University of Białystok, but due to the dramatic changes in the world in 2020–2022, he could not accept the invitation (he lives in Essen, Germany). Professor Libera’s cooperation with the Białystok academic community has continued since 1997, including joint editions of works of German Romanticism and biographies of its authors in the “Black Romanticism” Series, reviewing works, lectures at conferences organized by the Department of Philological Research “East - West” in Vilnius, Szetejnie, and Bialystok. In the interview, Professor Libera talks about his studies at the University of Wrocław, the master-apprentice relationship through which he formed his workshop, his travels in Switzerland, during which he established the unknown contexts of Juliusz Słowacki’s poetry, as well as his passion for writing culminating in the trilogy about Utopek. In the final part of the conversation, he talks about the former (fascinating to him) face of German culture and the contemporary destruction of its image.Leszek Libera (ur. w 1948 r. w Raciborzu) – emerytowany prof. zw. dr hab. Uniwersytetu Zielonogórskiego, z którym jest związany od blisko 20 lat; historyk literatury polskiej, tłumacz z języka niemieckiego, powieściopisarz. Specjalista z zakresu literatury oraz kultury romantyzmu polskiego i zachodnioeuropejskiego. Autor licznych studiów oraz monografii, m.in.: Juliusza Słowackiego „Podróż do Ziemi Świętej z Neapolu” (1993), Romantyczność i folklor: o twórczości Jacka Malczewskiego i Bolesława Leśmiana (1994), W Szwajcarii: studium o Juliuszu Słowackim (2001), Maria Stuart. Dramat Juliusza Słowackiego (2003), Zraniona iluzja: o „Balladynie” Juliusza Słowackiego i „Kocie w butach” Ludwiga Tiecka (2007), Mickiewicz i medycyna: szkice romantyczne (2010), Gottfried August Bürger – autor „Lenory” (2016). Wydał własne przekłady w naukowym opracowaniu, m.in.: Ludwig Tieck, Kot w butach, Świat na opak (2007), Ludwig Tieck, Blondyn Eckbert, Góra run (2022). Autor trylogii powieściowej: Der Utopek. Roman (2011), Buks Molenda. Roman (2012), Testament Utopka (2020), która ukazała się po polsku w przekładzie Sławy Lisieckiej. Mieszka w Essen, w Niemczech
Long-term evolution of N-terminal pro-brain natriuretic peptide levels and exercise capacity in 132 left ventricular assist device recipients
OBJECTIVES: N-terminal pro-brain natriuretic peptide (NT-proBNP) is a widely used biomarker in clinical practice in the context of heart failure. Little is known about the long-term evolution of NT-proBNP levels in left ventricular assist device (LVAD) recipients. Besides this, the potential correlation of NT-proBNP with exercise capacity on the long term after LVAD implantation has not been previously studied. METHODS: We retrospectively analysed 132 single-centre LVAD recipient records (HeartMate II/III; HeartWare; between March 2007 and January 2018; mean follow-up 559 days). Blood samples, 6-min walking test (6MWT) and maximal cardiopulmonary exercise test were performed in a standardized way. RESULTS: Pre-LVAD NT-proBNP levels were increased (9736 ± 1072 ng/l) and dropped significantly after implantation [14 days: 4360 ± 545 ng/l (P < 0.0001), 6 months: 1485 ± 139 ng/l (P < 0.0001)]. Afterwards a steady state was reached during follow-up (after 1 year: 1592 ± 214 ng/l, after 5 years: 1679 ± 311 ng/l). Submaximal exercise capacity significantly improved postoperatively [percentage of the predicted distance walked during the 6MWT 50 ± 2% (0-3 months); 61 ± 2% (3-6 months, P < 0.001)], with a steady state afterwards [66 ± 2% (6-12 months, P = 0.08); 64 ± 3%, P = 0.70 later on]. We found a gradual increment of percentage of the expected peak oxygen consumption postoperatively [44 ± 2% (0-3 months); 49 ± 2% (3-6 months); 52 ± 2% (6-12 months); 53 ± 1% (after 12 months)] with a significant improvement between 0 and 3 months versus after the first year on LVAD. Furthermore, we showed a significant moderate correlation between NT-proBNP levels and results at both the 6MWT (correlation coefficient: -0.31, P < 0.0001) and cardiopulmonary exercise testing (correlation coefficient: -0.28, P < 0.0001). CONCLUSIONS: NT-proBNP decreased on LVAD support. We showed that submaximal (6MWT) and maximal exercise capacity (cardiopulmonary exercise testing) improve after LVAD implantation and demonstrated an inverse correlation of both tests with NT-proBNP levels.sponsorship: Libera Fresiello is supported by the Fonds pour la Chirurgie Cardiaque N. 489618 and the KUL internal grant N. C14-18-080. Christophe Vandenbriele is supported by a research grant of the KOOR (Klinische Onderzoeksraad, University Hospitals Leuven). (Fonds pour la Chirurgie Cardiaque|489618, KUL internal grant|C14-18-080, KOOR (Klinische Onderzoeksraad, University Hospitals Leuven))status: Publishe
A patient-specific echogenic soft robotic left ventricle embedded into a closed-loop cardiovascular simulator for advanced device testing
Cardiovascular medical devices undergo a large number of pre- and post-market tests before their approval for clinical practice use. Sophisticated cardiovascular simulators can significantly expedite the evaluation process by providing a safe and controlled environment and representing clinically relevant case scenarios. The complex nature of the cardiovascular system affected by severe pathologies and the inherently intricate patient-device interaction creates a need for high-fidelity test benches able to reproduce intra- and inter-patient variability of disease states. Therefore, we propose an innovative cardiovascular simulator that combines in silico and in vitro modeling techniques with a soft robotic left ventricle. The simulator leverages patient-specific and echogenic soft robotic phantoms used to recreate the intracardiac pressure and volume waveforms, combined with an in silico lumped parameter model of the remaining cardiovascular system. Three different patient-specific profiles were recreated, to assess the capability of the simulator to represent a variety of working conditions and mechanical properties of the left ventricle. The simulator is shown to provide a realistic physiological and anatomical representation thanks to the use of soft robotics combined with in silico modeling. This tool proves valuable for optimizing and validating medical devices and delineating specific indications and boundary conditions.</p
Wastescapes in port cities. Naples and Rotterdam: a spatial and institutional comparison on the role of ports as promoters of circular economy
Ports have historically followed a linear model of growth. Formation, expansion,reallocation, abandonment, and redevelopments are just some of the steps that are followed over time by ports from all over the world. Circularity – a goal that both ports and cities hope to achieve in the near future – is not a new topic anymore. Although the global pressures to achieve this goal are immense, it can be stated that most port cities still have not yet made serious steps towards new circular models of growth. On the contrary, ports are still expanding, and they still generate serious amounts of waste, while also leaving networks of left-over territories that lay in states of wastefulness: port-city wastescapes. Two cases regarding these wastescapes are discussed. Naples, which is used to show land in limbo, while Rotterdam is used to show a port in transition. This article argues that a circular regeneration of these wastescapes can play a crucial role in re-imagining a new form of integration between the port, the city, and the metropolitan territory.History, Form & AestheticsEnvironmental Technology and Desig
King-Spirit in the Translation of Walter Schamschula
The article is devoted to the translation of Juliusz Słowacki’s King-Spirit into German. The author of the translation of this romantic epic is Walter Schamschula, a Slavist born in Prague in 1929. He became famous for his research into Russian, Czech and Polish literature, but most of all he became known as an outstanding translator. Aside the aforementioned King-Spirit, he translated Słowacki’s Beniowski and Forefathers’ Eve by Adam Mickiewicz into German. Thanks to work at the University of Berkeley, he met Czesław Miłosz (which influenced his interests). Schamschula not only translated The King-Spirit, his ambitions went in the artistic direction, as he himself admitted in the introduction: “Fidelity to the original in terms of meaning and form must give way to fidelity to a higher kind: the translator must have embodied himself so far into the world of the poet’s ideas, felt his poetic cosmos, that he should succeed in writing as if it were written by Słowacki himself, but writing in German”. Libera considers Schamschula’s comments on individual excerpts from Słovacki’s epic, often detailed and erudite explanations that sometimes take up a whole page of print, to be the most valuable in the publication.LESZEK LIBERA, prof. em. dr hab., pracownik Zakładu Literatury XIX wieku w Instytucie Filologii Polskiej Uniwersytetu Zielonogórskiego. Autor m.in. monografii: Gottfried August Bürger – autor „Lenory” (Białystok 2016) oraz Dzieci Słowackiego i inne szkice romantyczne (Zielona Góra 2017).LESZEK LIBERA, Prof. Dr. hab., employee of the Department of Literature of the 19th Century at the Institute of Polish Philology of Zielona Góra University. Author of, among others, the monograph: Gottfried August Bürger – autor „Lenory” (Białystok 2016) and Dzieci Słowackiego i inne szkice romantyczne (Zielona Góra 2017).Uniwersytet ZielonogórskiSłowacki J., König-Geist (Król-Duch), aus dem polnischen übertragen, mit Kommentar und Nachwort versehen von Walter Schamschula, Frankfurt am Main – Berlin – Bern 1998.Słowacki J., Beniowski, eine Versdichtung übersetzt und herausgegeben von Hans-Peter Hoelscher-Obermaier, Frankfurt am Main 1999.Mickiewicz A., Die Ahnenfeier. Ein Poem, übersetzt, herausgegeben und mit einem Nachwort versehen von Walter Schamschula. Vorwort von Hans Rothe, Köln – Weimar – Wien 1991.Libera L., „Beniowski” po niemiecku, [w:] Piękno Juliusza Słowackiego, t. I: Universum, praca zbiorowa pod red. J. Ławskiego, G. Kowalskiego, Ł. Zabielskiego, Białystok 2013.38939
From Wastescapes Towards Regenerative Territories. A Structural Approach for Achieving Circularity
In this chapter, the understanding of circularity goes beyond material resource management, deepening the spatial implications of a more circular management and use of wastescapes, investigated at the urban and metropolitan scale. Besides the health (care) related challenges presented by the current outbreak of the COVID-19 pandemic, additional ones related to our living environment have been—and will continue to be—an urgent call for academic researchers, designers and policymakers to find (eco)innovative solutions and strategies for enhancing the quality of life of all and the availability of more and more safe public (open) spaces and facilities to sustain this. In this situation, the spaces most at risk of urban and peri-urban areas could be found in the unresolved places which are defined as wastescapes, since they are in general still poorly used and valued. Building on the European H2020 research project REPAiR, the definition of wastescapes, provided in this study, builds upon work for two main cases: the metropolitan areas of Amsterdam (The Netherlands) and Naples (Italy). Wastescapes are discarded territories, however, they can also be understood as opportunities to realize regenerative concepts and support strategies related to environmental, spatial and social challenges of the territories and their surroundings. Core is then to improve the socio-ecological values of such territories. Wastescapes are different case by case, being affected by site-specific challenges and characterized by high complexity. The research presented in this chapter shows that the route towards a Circular Economy requires the consideration of wastescapes as ‘spatial resources’ important to be included in strategies of transition. It represents a fundamental step to overcome problems related to both resource (and land) scarcity, land use in general and spatial fragmentation, while providing opportunities to include through eco-innovative services other values than just the monetary ones to society. The spatial regeneration of wastescapes in the built environment involves a re-thinking of the structure of these areas in a larger (metropolitan) context. Within such metropolitan settings, in particular peri-urban territories, also referred to as the areas in-between urban and rural landscapes, are most affected and characterized by this problem of wastescapes.Environmental Technology and Desig
Circular planning and adaptive design strategies to recycle wasted landscapes: The per-urban territories of campania plain as a case study
The Campania Region, in the South of Italy, is a territory where numerous Wasted Landscapes (WL) are recognisable, as the result of serious socialand governmental problems.Through the last decades, many factors have been overlapping in this complex palimpsest: illegal developments and the measures to legitimizethem can be paradoxically understood as real cornerstones for the local planning system; the traces of the post-Fordist abandoned landscapes aremixed with the historical remains, showing the deep sense of identity that still persists in the territory. On the other hand, the Campania Plainis a porous territory characterised by an adaptive resilience. This is interwoven with the presence of areas of outstanding natural beauty, with aresilient interstitial agriculture, and with a fragmented but resistant economy.In this paper, two emblematic case-studies are discussed (Casaluce and Est-Naples), understanding WL as an additional category of waste withthe urgent need to be recycled, in order to: reactivate urban metabolism; to improve the quality of life, the spatial quality of the territory, and theregional economy.Environmental Technology and Desig
Molecular control of neuromuscular junction development
Skeletal muscle innervation is a multi-step process leading to the neuromuscular junction (NMJ) apparatus formation. The transmission of the signal from nerve to muscle occurs at the NMJ level. The molecular mechanism that orchestrates the organization and functioning of synapses is highly complex, and it has not been completely elucidated so far. Neuromuscular junctions are assembled on the muscle fibers at very precise locations called end plates (EP). Acetylcholine receptor (AChR) clusterization at the end plates is required for an accurate synaptic transmission. This review will focus on some mechanisms responsible for accomplishing the correct distribution of AChRs at the synapses. Recent evidences support the concept that a dual transcriptional control of AChR genes in subsynaptic and extrasynaptic nuclei is crucial for AChR clusterization. Moreover, new players have been discovered in the agrin-MuSK pathway, the master organizer of postsynaptical differentiation. Mutations in this pathway cause neuromuscular congenital disorders. Alterations of the postynaptic apparatus are also present in physiological conditions characterized by skeletal muscle wasting. Indeed, recent evidences demonstrate how NMJ misfunctioning has a crucial role at the onset of age-associated sarcopenia. © The Author(s) 2012
Beyond wastescapes: Towards circular landscapes. addressing the spatial dimension of circularity through the regeneration of wastescapes
Wastescapes are the result of unsustainable linear growth processes and their spatial consequences within the context of urban metabolic flows and related infrastructure. They represent the operational infrastructure for waste management and include Drosscapes, generating complex relations with the servicing and surrounding territory. In particular, the peri-urban areas are spatially affected by these processes. This often leads to ineffective use and/or abandonment because they are currently impossible to use, demanding impactful (and often expensive) regeneration and revalorization to make them usable again. Being part of the urban metabolic process, wastescapes are in a continuous state of dynamic equilibrium. They can be considered crucial areas from a metropolitan perspective because they have the potential to become innovative spatial contexts or resources in a Circular Economy (CE), which aims to overcome the crises of both resource scarcity and spatial fragmentation. However, common and shared definitions of wastescapes are still missing at the European policy level, as only classical categories of material waste are generally mentioned. Wastescapes can be considered as 'potentiality contexts' where developing, testing, and implementing Eco-Innovative Solutions (EIS) can be done. By doing so, wastescapes can help start transitions towards a CE. This can be achieved by using Peri-urban Living Labs (PULL), which have the potential to be the virtual and physical environments in which experimenting the collaborative co-creation process for developing EIS can be done. Doing so will allow for the improvement of waste management and for the revalorization of wastescapes in collaboration with all potential stakeholders.Environmental Technology and Desig
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