1,721,508 research outputs found
Personalized treatment targets in rheumatoid arthritis
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139137.pdf (Publisher’s version ) (Open Access)Radboud Universiteit Nijmegen, 20 maart 2015Promotor : Riel, P.L.C.M. van Co-promotor : Fransen, J
Treatment strategies in early Rheumatoid Arthritis.
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83231.pdf (Publisher’s version ) (Open Access)Radboud Universiteit Nijmegen, 01 december 2010Promotor : Riel, P.L.C.M. van Co-promotor : Fransen, J.172 p
Cardiovascular disease in rheumatoid arthritis: risk profile and risk prediction
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167168.pdf (Publisher’s version ) (Open Access)Radboud University, 31 maart 2017Promotor : Riel, P.L.C.M. van Co-promotores : Fransen, J., Popa, C
Participatory development and evaluation of an online self-management enhancing program for patients with Rheumatoid Arthritis
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205661.pdf (Publisher’s version ) (Open Access)Radboud University, 23 augustus 2019Promotores : Nijhuis-van der Sanden, M.W.G., Dulmen, A.M. van Co-promotores : Gaal, H.G.I. van, Fransen, J
Physical activity and fatigue in rheumatoid arthritis: a vicious circle?
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144027.pdf (Publisher’s version ) (Open Access)Radboud Universiteit Nijmegen, 16 oktober 2015Promotores : Riel, P.L.C.M. van, Bleijenberg, G. Co-promotores : Fransen, J., Repping-Wuts, J.W.J
Tight control in Rheumatoid Arthritis: bridging the gap between evidence and daily clinical practice
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96468.pdf (Publisher’s version ) (Open Access)Radboud Universiteit Nijmegen, 18 maart 2011Promotores : Riel, P.L.C.M. van, Grol, R.P.T.M. Co-promotores : Fransen, J., Hulscher, M.E.J.L
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Evaluation of new drugs in daily clinical practice: anti-TNF alpha in rheumatoid arthritis patients.
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65606_evalofned.pdf (Publisher’s version ) (Open Access)
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70338.pdf (Publisher’s version ) (Open Access)The objective of this thesis was to explore the value and the validity of data collected in daily clinical practice for drug evaluation and cost-effectiveness studies, using data collected on TNFa blocking agents in rheumatoid arthritis. First, the need for and value of information from daily clinical practice was researched. Together, the results of Chapters 3, 4 and 5 illustrated that treatment of RA patients with anti-TNFa blocking agents in daily clinical practice was different from what was expected from the performed RCTs and the guidelines developed on the basis of the RCTs. Data from a daily clinical practice registry can be used to get insight in the actual use and realized effects of medications in daily clinical practice, in contrast to the controlled setting of a RCT. Furthermore, data from clinical practice can be used to estimate the impact on the budgets in health care by implementing a new intervention in daily clinical practice. The second part of this thesis addressed the use of patient self reported measures in large daily clinical practice registries. Because the use of patient self reported measures could be very convenient to evaluate drug therapy in daily clinical practice, its was researched whether these measures could substitute more objective measures like the disease activity score. Chapters 6 and 7 of this thesis showed that patient reported measures cannot substitute objective measures of disease activity. It was shown that response shifts occurred and greatly confounded the outcomes of the patient-self-reported ratings. It was not possible to correct for response shift because it led to the paradoxical result that clinical non-responders increased significantly on a self-reported measure. It is therefore recommended to evaluate drugs in daily clinical practice also with a objective measure of disease activity.RU Radboud Universiteit Nijmegen, 07 november 2008Promotor : Riel, P.L.C.M. van Co-promotores : Adang, E.M.M., Fransen, J.174 p
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