1,626 research outputs found
First person – Melanie Ridgway
First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Melanie Ridgway is first author on ‘ Analysis of sex-specific lipid metabolism in Plasmodium falciparum points to importance of sphingomyelin for gametocytogenesis’, published in JCS. Melanie conducted the research described in this article while a PhD candidate in Alexander Maier's lab at Biomedical Science and Biochemistry, Research School of Biology, Australian National University, Australia. She is now a postdoc in the lab of David Horn at Wellcome Centre for Anti-Infectives Research, Biological Chemistry and Drug Discovery, University of Dundee, Dundee, UK, investigating the cell biology of unicellular parasites
Challenges and Strategies for Family Foundations With Geographically Dispersed Board Members
· This article, based on interviews with leaders of 10 family foundations, investigates the impact of geographic dispersion on governance, administration, decision making, and grantmaking activities.
· The greatest challenges for family foundations with dispersed boards involve assembling an appropriate staff, ensuring strong communication between staff and board members, and focusing the organization’s mission. Maintaining family board member interest in the foundation’s geographic area and bridging and strengthening ties between generations were also concerns.
· In order to maintain family legacies, all case-study foundations found unique ways to overcome challenges and were deliberate in ensuring that board members stayed actively engaged in the work of the foundation.
· Common strategies for keeping board members involved include providing flexible but clear direction to nonfamily staff, developing stepping stone board positions for successive generations, and balancing the mission with the desire to build family ties
Inclusive research: Research methods
First published Open Access under a Creative Commons license as What is Inclusive Research?, this title is now also available as part of the Bloomsbury Research Methods series. This book describes and defines inclusive research, outlining how to recognize it, understand it, do it, and know when it is done well. In doing so it addresses the areas of overlap and distinctiveness in relation to participatory, emancipatory, user-led and partnership research as well as exploring the various practices encompassed within each of these inclusive approaches. The author, Melanie Nind, focuses on how and why more inclusive approaches to research have evolved. She positions inclusive research within the key debates and shifts in policy, defines key ideas and terms, discusses the contested nature of inclusive research and illustrates a range of approaches using exemplars. The aim is to discuss the range of challenges involved and to examine the degree to which these challenges have so far been met.</p
Interview with Melanie Rae Thon
native of Montana, Melanie Rae Thon is an award-winning short story and novel author who lives in Salt Lake City and teaches at the University of Utah
An individual-based model to explore the impact of psychological stress on immune infiltration into tumour spheroids
In recent in vitro experiments on co-culture between breast tumour spheroids and activatedimmune cells, it was observed that the introduction of the stress hormone cortisolresulted in a decreased immune cell infiltration into the spheroids. Moreover, the presenceof cortisol deregulated the normal levels of the pro- and anti-inflammatory cytokines IFN-γand IL-10. We present an individual-based model to explore the interaction dynamics betweentumour and immune cells under psychological stress conditions. With our model,we explore the processes underlying the emergence of different levels of immune infiltration,with particular focus on the biological mechanisms regulated by IFN-γ and IL-10. Theset-up of numerical simulations is defined to mimic the scenarios considered in the experimentalstudy. Similarly to the experimental quantitative analysis, we compute a score thatquantifies the level of immune cell infiltration into the tumour. The results of numericalsimulations indicate that the motility of immune cells, their capability to infiltrate throughtumour cells, their growth rate and the interplay between these cell parameters can affectthe level of immune cell infiltration in different ways. Ultimately, numerical simulationsof this model support a deeper understanding of the impact of biological stress-inducedmechanisms on immune infiltration
When Do Children Dislike Ingroup Members? Resource Allocation from Individual and Group Perspectives
Do children like ingroup members who challenge group norms about resource allocation? Further, do children evaluate from their own individual perspective? Participants (N = 381), aged 9.5 and 13.5 years, evaluated members of their own group who deviated from group norms about resource allocation by either: (1) advocating for equal allocation in contrast to the group norm of inequality; or (2) advocating for inequality when the group norm was to divide equally. With age, participants differentiated their own individual favorability from the group's favorability of deviant members of the ingroup. Further, when deciding between group loyalty and equal allocation, children and adolescents gave priority to equality, rejecting group decisions to dislike ingroup members who advocated for equality
How might a culture of appreciation be cultivated at JIBC?
An appreciative workplace culture has been demonstrated to increase the health of its employees which in turn increases the health of the organization by reducing absenteeism caused by sick leave, stress leave, and turnover (Chapman & White, 2011). Although limited, all previous literature demonstrated positive impacts for organizations that develop and sustain a culture of appreciation. By exploring appreciation within JIBC through employee dialogue, the opportunity existed to enhance the health and functioning of the organization.Not peer reviewedThis poster is related to Melanie Chernoff's Royal Roads University Masters Thesisstress; sick leave; appreciation; employee motivation; absenteeis
Monumental Impact – Honoring the Life & Legacy of Dr. Melanie Buffington
The article honors the impactful work of the late Dr. Melanie Buffington. The author discusses their experience recognizing the overlap between Dr. Buffington’s work and the work of Monument Lab, a public art and history studio based in Philadelphia. Honoring Dr. Buffington’s legacy, the author recommends Monument Lab’s field trip guide as a tool for engaging students in critical thinking and meaningful conversations considering and reimagining public art and public spaces
Conducting systematic review in education: a reflexive narrative
The evaluation of systematic review as part of the evidence-based or evidence-informed practice movement is a dominant theme in current debates in educational research. This article contributes to the debate by offering a personal, reflexive narrative on the process of doing systematic review, relating some of the arguments regarding the merits and problems of systematic review to the author's own experience and to parallels in other research approaches. The author highlights areas where systematic review might usefully develop and evolve
PENGARUH SOSIAL TERHADAP PERUBAHAN SIKAP TOKOH MELANIE CHARMICHAEL DALAM FILM SWEET HOME ALABAMA
In human life, human beings will not be separated from problems, any time strives to get trough the problem, ranging from minor problems in life, to the tragedy thet changed someone’s life. About Melanie Charmichael in this thesis is living in superioritas a tragedy happens and change life.
The purpose of this thesis is to describe how the tragedy changed the attitude and character Melanie until she create a new identity and analyzing the psychological individual by bad attitude that happen in the changed of life.
In analyzing the psychological individual that happened to Melanie Charmichael, author tried to apply a Adler with using a library research methods, that is done reading books, articles, or any written an visual document that related to the topic
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