68 research outputs found
Static and Dynamic Data Models for the Storage Resource Manager v2.2
No full textWe present a conceptual model for the Storage Resource Manager, the standard interface adopted for the storage systems of the Worldwide LHC Computing Grid. This model provides a clear and concise definition of the structural and behavioral concepts underlying the interface specification and is meant to support service and application development. Different languages (natural language, UML diagrams, and simple set-theoretic and logical notation) are used to describe different aspects of the model
A Model for the Storage Resource Manager
No full textThe Storage Resource Manager has been proposed as a standard interface for high-end storage systems deployed on Grid architectures. In this paper we propose a conceptual model for the SRM that should supplement its API specification with a clear and concise definition of its underlying structural and behavioral concepts. This model would make it easier to define its semantics, it would help service and application developers, and provide for a more rigorous validation of implementations. Different notations are used as appropriate to define different aspects of the model
Experiences in testing a Grid service in a production environment
No full textThis paper reports on the problems and solutions related to the testing of
several implementations for conformance to a standard storage management interface adopted in the Worldwide LHC Computing Grid
Relaxed Data Consistency with CONStanza
No full textData replication is an important aspect in a Data Grid for increasing fault tolerance and availability. Many Grid replication tools or middleware systems deal with read-only files which implies that replicated data items are always consistent. However, there are several applications that do
require updates to existing data and the respective replicas. In this article we present a replica consistency service that allows for replica updates in a single-master scenario with lazy update synchronisation. The system allows for updates of (heterogeneous) relational databases, and it is designed to support flat files as well. It keeps remote replicas synchronised and partially (“lazily”) consistent. We report on
the design and implementation of a novel “relaxed” replica consistency service and show its usefulness in a typical application use case
A performance study on the synchronisation of heterogeneous Grid databases using CONStanza
No full textIn Grid environments, several heterogeneous database management systems are used in various administrative domains. However, data exchange and synchronisation need to be available across different sites and different database systems. In this article we present our data consistency service CONStanza and give details on how we achieve relaxed update synchronisation between different database implementations. The integration in existing Grid environments is one of the major goals of the system. Performance tests have been executed following a factorial approach. Detailed experimental results and a statistical analysis are presented to evaluate the system components and drive future developments. (C) 2010 Elsevier B.V. All rights reserved
The Simultaneous Assessment of Time and Motion Response during Dual Tasks
No full textMeasurement of reaction time in clinical settings is generally employed to assess cognitive abilities by having a subject perform standard simple tests. In this study, a new method of measuring response time (RT) was developed using a system composed of LEDs that emit light stimuli and are equipped with proximity sensors. The RT is measured as the time taken by the subject to turn off the LED target by moving the hand towards the sensor. Through an optoelectronic passive marker system, the associated motion response is assessed. Two tasks of 10 stimuli each were defined: simple reaction time and recognition reaction time tasks. To validate the method implemented to measure RTs, the reproducibility and repeatability of the measurements were estimated, and, to test the method’s applicability, a pilot study was conducted on 10 healthy subjects (6 females and 4 males, age = 25 ± 2 years), reporting, as expected, that the response time was affected by the task’s difficulty. Unlike commonly used tests, the developed method has proven to be adequate for the simultaneous evaluation of the response in terms of time and motion. Furthermore, thanks to the playful nature of the tests, this method could also be used for clinical and pediatric applications to measure the impact of motor and cognitive impairments on RT
Assegno divorzile e convivenza more uxorio
No full textThe essay aims at highlighting the potential implications of the recent leading case law relating to the nature of divorce spouse support. By commenting the case at stake – after recalling the case law evolution on the issue – the author tries to point-out the rationale underlying the Supreme Court’s decision no. 18287 of 2018 and to provide arguments in support of the compensatory nature of divorce spouse support, as affirmed by such decision. Lastly, the essay addresses the issue of the relationship between divorce spouse support and more uxorio cohabitation. In this respect, the decision of the Court is criticised since it appears not to have taken in due account the effects of a combined reading of both the Supreme Court’s mentioned case law and the law 20 May 2016, no 76 (which has regulated, inter alia, more uxorio cohabitations), to provide a different view on the issu
Testing the accuracy and reliability of palmar friction ridge comparisons – A black box study
No full textGitlab repository with all files used for the paper
Eldridge, H., M. De Donno and C. Champod (2021). "Testing the accuracy and reliability of palmar friction ridge comparisons – A black box study." Forensic Science International 318: 110457.
https://doi.org/10.1016/j.forsciint.2020.110457
Raw data are in in data folder.
This project was supported by Award No. 2017-DN-BX-0170, awarded by the National Institute of Justice, Office of Justice Programs, U.S. Department of Justice. The opinions, findings, and conclusions or recommendations expressed in this publication/program/exhibition are those of the author(s) and do not necessarily reflect those of the Department of Justice
Sex Influence on Autophagy Markers and miRNAs in Basal and Angiotensin II-Treated Human Umbilical Vein Endothelial Cells
No full textCardiovascular diseases (CVD) display many sex and gender differences, and endothelial dysfunction, angiotensin II (Ang II), and autophagy represent key factors in the autophagic process Therefore, we studied whether Ang II modulates the mentioned processes in a sex-specific way in HUVECs obtained from healthy male and female newborns. In basal HUVECs, the Parkin gene and protein were higher in FHUVECs than in MHUVECs, while the Beclin-1 protein was more expressed in MHUVECs, and no other significant differences were detected. Ang II significantly increases LAMP-1 and p62 protein expression and decreases the expression of Parkin protein in comparison to basal in MHUVECs. In FHUVECs, Ang II significantly increases the expression of Beclin-1 gene and protein, and Parkin gene. The LC3 II/I ratio and LAMP-1 protein were significantly higher in MHUVECs than in FHUVECs, while Parkin protein was significantly more expressed in Ang II-treated FHUVECs than in male cells. Ang II affects the single miRNA levels: miR-126-3p and miR-133a-3p are downregulated and upregulated in MHUVECs and FHUVECs, respectively. MiR-223 is downregulated in MHUVEC and FHUVECs. Finally, miR-29b-3p and miR-133b are not affected by Ang II. Ang II effects and the relationship between miRNAs and organelles-specific autophagy is sex-dependent in HUVECs. This could lead to a better understanding of the mechanisms underlying sex differences in endothelial dysfunction, providing useful indications for innovative biomarkers and personalized therapeutic approaches
- …
