15,952 research outputs found
alexander-held/cabinetry: v0.2.2
No full textThis release enables the use of all pyhf backends and adds a helper function to set up custom logging output. It also fixes Asimov dataset generation for models with shapesys modifiers.
To set a pyhf backend, use the pyhf API: pyhf.set_backend. This backend is no longer overridden within cabinetry and therefore used for inference and other operations in pyhf.
Full list of changes:
chore: updating version to 0.2.2 (#239)
fix: Asimov generation with shapesys modifiers (#238)
feat: helper function for log formatting (#237)
feat: support all pyhf backends (#228)
fix: workaround for coverage bug (#234)
fix: simplify example workspace and small type check fix (#235)
chore: add standard venv names and notebook checkpoints to gitignore (#229)
fix: compatibility with mypy 0.900 (#232)
fix: NamedTuple compatibility in typeguard, Codecov token for upload (#230)
refactor: histogram normalization (#226)
test: extend coverage for workspace building (#225
Douglas Alexander Stewart, poet, author and playwright
No full textDouglas Alexander Stewart, poet, author and playwrigh
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Das Recht auf Datenportabilität ::Art. 20 DSGVO als Schnittstelle zwischen Wettbewerbsförderung und Datenschutz /
No full textFrom publisher's website: Datenportabilität wird seit Beginn des Internetzeitalters als Garant für ein freies und offenes Internet angesehen. Die DSGVO versucht nun, dieses Bedürfnis erstmals gesetzgeberisch zu erfüllen. Die Kodifikation des Rechts auf Datenportabilität in Art. 20 DSGVO befindet sich dabei an einer immer wichtiger werdenden Schnittstelle zwischen Datenschutzrecht und Wettbewerbsrecht. Die zuweilen als widersprüchlich empfundene Verortung als datenschutzrechtliches Betroffenenrecht wird an dieser Schnittstelle eingeordnet. Alexander Fix beleuchtet dabei Zweck und Regelungsgehalt des Art. 20 DSGVO vor diesem Hintergrund erstmals umfassend und ergänzt dies um eine Betrachtung einiger technischer Aspekte aus juristischer Sicht
Data from: Do chromosome rearrangements fix by genetic drift or natural selection? Insights from Brenthis butterflies
No full text[VCFs] There are four VCF files (*vcf.gz). All of them contain filtered SNP calls.
Samples from all three Brenthis species mapped to the Fabriciana adippe reference genome (used for demographic inference)
B. daphne samples mapped to the B. daphne reference genome (used for ROH identification and sweep inference)
B. ino samples mapped to the B. ino reference genome (used for ROH identification and sweep inference)
B. hecate samples mapped to the B. hecate reference genome (used for ROH identification and sweep inference)[Callable sites bed files] These files (*.bed) contain intervals where genotypes are callable (given coverage and indels). Each file is associated with one of the VCF files above. The bed file for demographic inference only contains 4D sites, whereas the bed files for sweep inference only contain intergenic sites.[3D-SFS] These files (.obs) contain the three-dimensional SFS for *B. daphne, B. ino and B. hecate. One contains the unfolded spectra (DSFS) and the other the folded spectra (MSFS). They are in the format expected by fastsimcoal2.[Blockwise SFS] Each file (.formatted_blocks.tsv) contains a blockwise SFS for 1 Mb around a chromosome fusion in B. daphne, B. ino or B. hecate, or, alternatively, the bSFS across an entire chromosome.* This is the input for the sweep inference.[Inferred selective sweeps] These files (*sweeps.tsv) contain results of the inferred selective sweeps, either around fusion points of from loci sampled elsewhere in the genome.[ROH summary] A tsv file giving a summary of ROH in each Brenthis individual.Large-scale chromosome rearrangements, such as fissions and fusions, are a common feature of eukaryote evolution. They can have considerable influence on the evolution of populations, yet it remains unclear exactly how rearrangements become established and eventually fix. Rearrangements could fix by genetic drift if they are weakly deleterious or neutral, or they may instead be favoured by positive natural selection. Here we compare genome assemblies of three closely related Brenthis butterfly species and characterise a complex history of fission and fusion rearrangements. An inferred demographic history of these species suggests that rearrangements became fixed in populations with large long-term effective size (Ne). However, we also find large runs of homozygosity within individual genomes and show that a model of population structure with smaller local Ne can reconcile these observations. Using a recently developed analytic framework for characterising hard selective sweeps, we find that chromosome fusions are not enriched for evidence of past sweeps compared to other regions of the genome. Nonetheless, one chromosome fusion in the B. daphne genome is associated with a valley of diversity where genealogical branch lengths are distorted, consistent with a selective sweep. Our results suggest that drift is a stronger force in these populations than suggested by overall genetic diversity, but that the fixation of strongly underdominant rearrangements remains unlikely. Additionally, although chromosome fusions do not typically exhibit signatures of selective sweeps, a single example raises the possibility that natural selection may sometimes play a role in their fixation.Natural Environment Research Council : NE/S007407/1. Natural Environment Research Council : NE/L011522/1. European Research Council : ModelGenomLand 757648.Peer reviewe
Author inscription in William Hazlitt, essayist and critic; selections from his writings, with a memoir, biographical and critical by Alexander Ireland
No full textAuthor's gift inscription, "To W. C. Hazlitt Esq with kind regards, from Alexr Ireland," with tipped-in review of the book.ASU Library edition has inscription from Ireland to Hazlitt [a child of William Hazlitt?].
Hazlitt , William, 1778-1830.
Ireland, Alexander, 1810-1894
Jessica Decky Alexander, Oral History Interview, 2024
No full textDecky Alexander is a Drama Professor and the director of academic engagement programs (Engage@EMU) at Eastern Michigan University. In this interview, Alexander recounts how she became interested in theater, growing up in the Chicago area, and the impact college had on expanding her worldview. Alexander describes her theatre initiatives, working to improve harmful public school policies, and how she ended up at Eastern Michigan University. Alexander explains her life during her “year of yes”, getting involved with the Jewish Federation in Washtenaw County, and her involvement in resettling Afghan families into student housing at EMU in 2022. Alexander explores how she thinks EMU can better engage with the international community, her desire to help formerly incarcerated people get an education, and other humanitarian initiatives that she has been involved with.https://commons.emich.edu/oral_histories/1170/thumbnail.jp
The Author of the Alexander Romance
No full textThis paper, which is based on a portion of the introduction of the author’s edition of Il Romanzo di Alessandro (Mondadori: Fondazione Valla 2007), surveys the generic components of the Alexander Romance in an attempt to arrive at a definition of the work. The argument builds on Merkelbach’s categorisation of elements and uses Fusillo’s insight into the novel as an ‘encyclopaedic genre’ to propose that ‘historical novel’ is not, as Hägg contended, a misnomer for the work. The main components I discuss are: ‘life’; praxeis; chreiai; Cynic elements, including choliambic poetry and utopian perspectives; and the Egyptian aspects of the narrative. A concluding jeu d’esprit offers a characterisation of the putative author, his antecedents and his process of composition.Richard Stoneman was for 25 years editor for classics at Croom Helm and then Routledge. In 1997 he was appointed an Honorary Fellow in the department of classics, University of Exeter. After retiring from publishing in 2006 he has been pursuing his researches on the Alexander legends and teaching a course on the subject at Exeter. His Penguin translation of the Alexander Romance was published in 1991, and a volume of translated Legends of Alexander the Great appeared from Everyman in 1994. Also in 1994 he co-edited Greek Fiction with John Morgan. His edition of the Greek recensions of the Alexander Romance was published (volume I) by the Fondazione Valla in 2007 – volumes II and III will follow over the next few years – and his Alexander the Great: A Life in Legend appeared from Yale University Press in spring 2008. He is the author of a number of other books on Greek history and travel, and is writing a book on oracles
Author Correction: The dengue-specific immune response and antibody identification with machine learning
No full textCorrection to: npj Vaccineshttps://doi.org/10.1038/s41541-023-00788-7, published online 20 January 2024 In this article, the affiliation details for author Alexander Horst were incorrectly given as Alexander Horst1,2 but should have been Alexander Horst1 and other affiliations are renumbered. The original article has been corrected
Alexander Woollcott, author and stage actor
No full textAlexander Woollcott, author and stage actorTo order a reproduction, inquire about permissions, or for information about prices see:
http://www.lib.washington.edu/specialcollections/services/reproduction/reproduction
Please cite the Order NumberScanned at 600ppi with an Epson 20000 flatbed scanner. Image then rotated, cropped, level-adjusted, and sharpened using Photoshop CS3. Converted to a JPEG2000 image upon ingest into CONTENTdm
Lori Alexander: Cook Prize 2025, Silver Medal Acceptance Speech
No full textAuthor Lori Alexander gives an acceptance speech for Cactus Queen: Minerva Hoyt Establishes Joshua Tree National Park (Calkins Creek)https://educate.bankstreet.edu/cook/1017/thumbnail.jp
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