32 research outputs found
PERBANDINGAN KUALITAS PELAYANAN INSTALASI FARMASI PASIEN BPJS RAWAT JALAN RUMAH SAKIT PEMERINTAH DAN SWASTA KOTA SEMARANG
7 ABSTRACT Currently there are many complaints against service quality of BPJS patients in pharmacy some hospitals. This study aimed to compare the service quality of BPJS outpatient pharmacy installation at government and and public private hospital Semarang in terms of five dimensions of SERVQUAL. This study was an analytic survey research with cross sectional study design. Sample was BPJS outpatient or patient's family who took the drug in one of the government hospital Semarang (Tugurejo Hospital’s pharmacy) and one of the public private hospital Semarang (Sultan Agung Hospital’s pharmacy). The sampling technique used purposive sampling method, and used questionnaires to collect data. Expectations and performance scores had been analized used gap analysis and Mann-Whitney test to compare the service quality of BPJS outpatient pharmacy installation at government and and public private hospital Semarang in terms of five dimensions of SERVQUAL The service quality that terms of five dimensions of SERVQUAL in both of two hospital’s pharmacy installation Semarang could not meet the expectations of BPJS outpatient yet. The biggest gap according to BPJS outpatient in Sultan Agung Hospital’s pharmacy and Tugurejo Hospital’s pharmacy Semarang was the dimension of responsiveness with value respectively -0.73 and -0.63. Dimension that has met the expectations of BPJS outpatients Sultan Agung Hospital’s pharmacy was tangible dimension with value 0.03. There were significant differences between service quality of BPJS outpatient pharmacy installation at government and and public private hospital Semarang above tangible (p. 0,000), and reliability dimension (p. 0,000). Key words : Service quality, Tugurejo Hospital’s pharmacy, Sultan Agung Hospital’s pharmacy, BPJS outpatient, SERVQUA
Jurnal Ilmu Farmasi & Farmasi Klinik Vol.9 No.2 Desember 2012
iJurnal Ilmu Farmasi & Farmasi Klinik Journal of Pharmaceutical Science & Clinical PharmacyPemimpin Umum/ Penanggung jawab Dekan Fakultas Farmasi Universitas Wahid HasyimPemimpin Redaksi Wakil Dekan Bidang Akademik dan Kemahasiswaan Fakultas Farmasi Universitas Wahid Hasyim Redaktur Ahli Dr. Sumantri, M.S., Apt Prof. Dr. Suwijiyo Pramono, Apt. Prof. Dr. Mustofa, MKes. Apt. Dr. Mimiek Murukmihadi, SU., Apt Redaktur Pelaksana Aqnes Budiarti, M.Sc., Apt Staf Redaksi : Maulita Cut Nuria, M.Sc., Apt Maria Ulfah, M.Sc., Apt Sugiyono, M.Sc., Apt Risha Fillah Fithria, M.Sc., Apt Ririn Lispita Wulandari., S.Farm., Apt Sekretaris Redaksi Devi Nisa Hidayati, S.Farm Distributor Rachmad Wahyudi Alamat Redaksi/Tata Usaha Fakultas Farmasi Universitas Wahid Hasyim Jl. Menoreh Tengah X/22 Sampangan Semarang Telp. 024-8505680, 8505681 Fax. 024-8505680E-mail : [email protected] Terbit 2 kali setahun sejak September 2004ISSN : 1693-7899Volume 9 No 2 Desember 2012iiJurnal Ilmu Farmasi & Farmasi Klinik Journal of Pharmaceutical Science & Clinical Pharmacy DAFTAR ISIUji Sitotoksisitas Fraksi n-Heksana Ekstrak Etanol Herba Alfalfa (Medicago Sativa L.) Pada Sel T27D dan Sel Hela Serta Identifikasi Kandungan Senyawa Kimianya. Sri Susilowati , Anggun Claresa, Ibrahim Arifin..........................................................1 -9Evaluasi Kandungan Vitamin C Dalam Madu Randu dan Madu Kelengkeng dari Peternak Lebah dan Madu Perdagangan di Kota Semarang. Aqnes Budiarti dan Diah Fahmisul Istyaningrum…………………………………….10 - 15Aktivitas Antidiare Ekstrak Etanol Daun Randu (Ceiba petandra L. Gaern.) Pada Mencit Jantan Galur Balb/C Yance Anas, Risha Fillah Fithria, Yulia Ayu Purnamasari, Kusuma Arum Ningsih, Andri Geger Noviantoro, dan Suharjono……………………………………………...16 - 22Uji Aktivitas Imunostimulator Fraksi Air Dari Ekstrak Etanol Kelopak Bunga Rosella (Hibiscus sabdariffa L.) Terhadap Proliferasi Sel Limposit Mencit Galur Swiss Secara In Vitro Beserta Identifikasi Kandungan Kimianya. Oktarina Heni Puspitowati, Maria Ulfah dan Ediati Sasmito………………………...23 - 31Pengaruh Variasi Kadar Amilum Garut (Maranta arundinaceae Linn) Sebagai Bahan Pengikat Terhadap Sifat Fisik dan Kimia Tablet Parasetamol Sugiyono, Pipit Murdiyani dan Yulias Ninik W...........................................................32 - 37Perbedaan Pengaruh Lama Penyimpanan Larutan Susu Bubuk Full Cream dan Larutan Susu Kental Manis Terhadap Kadar Glukosa Risha Fillah Fithria, Agus Suprijono dan Maywan Hariono.......................................38 – 42ISSN : 1693-7899Volume 9 No 2 Desember 2012iiiPENGANTAR REDAKSI Assalamualaikum Wr. Wb. Alhamdulillah seiring dengan perjalanan Fakultas Farmasi Universitas Wahid Hasyim Semarang, Jurnal Ilmu Farmasi dan Farmasi Klinik (JIFFK) telah memasuki tahun ke-lima semenjak penerbitan perdana tahun 2004. Kami tetap berharap bahwa JIFFK dapat memberikan kontribusi bagi perkembangan ilmu farmasi dan farmasi klinik. Kami berharap bahwa JIFFK ini dapat digunakan sebagai wadah bagi para peneliti, akademisi dan pemerhati ilmu farmasi dan farmasi klinik untuk mempublikasikan hasil penelitian atau pemeikirannya. Demi menjaga eksistensi dan sustainabilitas JIFFK kami senantiasa memohon sumbangan tulisan atau artikel dari para peneliti. Kami selalu berusaha untuk dapat meningkatkan kualitas dari setiap penerbitan JIFFK ini, karena kami memiliki cita-cita supaya JIFFK dapat terakreditasi dari Dikti, DepDikNas-RI Akhir kata kami sampaikan terima kasih yang sebesar-besarnya kepada semua pihak yang telah membantu terlaksananya penerbitan ini. Kritik dan saran selalu kami nantikan dari pembaca sekalian demi perbaikan dan kemajuan JIFFK. Wassalamu’alaikum Wr. Wb. Semarang, Desember 2012 Hormat kami Redaks
PERBEDAAN PENGARUH LAMA PENYIMPANAN LARUTAN SUSU BUBUK FULL CREAM DAN LARUTAN SUSU KENTAL MANIS TERHADAP KADAR GLUKOSA
ABSTRACTMilk and the products which have expired usually be thrown by people immediately.However, those are still having lactose content even do not like as much as a fresh milk. Lactose content of milk and the expired products can be extracted and then hydrolized to yield glucose and galactose. The glucose content can be determined, so it will give information about ehancing value of expired milk that the glucose content can be developed furthermore to larger scale (industrial scale). This research was aimed to know influence of storage duration toward glucose content of fresh milk, full cream milk powder solution and sweet concentrate milk solution, and comparison of glucose content for each product. Research object was glucose content of fresh milk, full cream milk powder solution and sweet concentrate milk solution which was store for 0, 1, 2, 3, 4 and 5 days with gravimetric methode and determined by Friedman test; comparison of glucose content for each product determined by Anova because its distribution are normal and its variation are homogen, or by Kruskal-Wallis because its distribution are unnormal and its variation are unhomogen using SPSS version 15.0 with level of statistic confidence 99%. The result showed that the storage duration was influenced toward glucose content of fresh milk, full cream milk powder solution and sweet concentrate milk solution significantly and there are significance difference of glucose content for each products with the manipulation on storage duration.Key words : storage duration, glucose, fresh milk, full cream milk powder solution and sweet concentrate milk solutio
Jurnal Ilmu Farmasi & Farmasi Klinik Vol.9 No.2 Desember 2012
IJurnal Ilmu Farmasi & Farmasi Klinik Journal of Pharmaceutical Science & Clinical PharmacyPemimpin Umum/ Penanggung jawab Dekan Fakultas Farmasi Universitas Wahid HasyimPemimpin Redaksi Wakil Dekan Bidang Akademik dan Kemahasiswaan Fakultas Farmasi Universitas Wahid Hasyim Redaktur Ahli Dr. Sumantri, M.S., Apt Prof. Dr. Suwijiyo Pramono, Apt. Prof. Dr. Mustofa, MKes. Apt. Dr. Mimiek Murukmihadi, SU., Apt Redaktur Pelaksana Aqnes Budiarti, M.Sc., Apt Staf Redaksi : Maulita Cut Nuria, M.Sc., Apt Maria Ulfah, M.Sc., Apt Sugiyono, M.Sc., Apt Risha Fillah Fithria, M.Sc., Apt Ririn Lispita Wulandari., S.Farm., Apt Sekretaris Redaksi Devi Nisa Hidayati, S.Farm Distributor Rachmad Wahyudi Alamat Redaksi/Tata Usaha Fakultas Farmasi Universitas Wahid Hasyim Jl. Menoreh Tengah X/22 Sampangan Semarang Telp. 024-8505680, 8505681 Fax. 024-8505680E-mail : [email protected] Terbit 2 kali setahun sejak September 2004ISSN : 1693-7899Volume 9 No 2 Desember 2012iiJurnal Ilmu Farmasi & Farmasi Klinik Journal of Pharmaceutical Science & Clinical Pharmacy DAFTAR ISIUji Sitotoksisitas Fraksi n-Heksana Ekstrak Etanol Herba Alfalfa (Medicago Sativa L.) Pada Sel T27D dan Sel Hela Serta Identifikasi Kandungan Senyawa Kimianya. Sri Susilowati , Anggun Claresa, Ibrahim Arifin..........................................................1 -9Evaluasi Kandungan Vitamin C Dalam Madu Randu dan Madu Kelengkeng dari Peternak Lebah dan Madu Perdagangan di Kota Semarang. Aqnes Budiarti dan Diah Fahmisul Istyaningrum…………………………………….10 - 15Aktivitas Antidiare Ekstrak Etanol Daun Randu (Ceiba petandra L. Gaern.) Pada Mencit Jantan Galur Balb/C Yance Anas, Risha Fillah Fithria, Yulia Ayu Purnamasari, Kusuma Arum Ningsih, Andri Geger Noviantoro, dan Suharjono……………………………………………...16 - 22Uji Aktivitas Imunostimulator Fraksi Air Dari Ekstrak Etanol Kelopak Bunga Rosella (Hibiscus sabdariffa L.) Terhadap Proliferasi Sel Limposit Mencit Galur Swiss Secara In Vitro Beserta Identifikasi Kandungan Kimianya. Oktarina Heni Puspitowati, Maria Ulfah dan Ediati Sasmito………………………...23 - 31Pengaruh Variasi Kadar Amilum Garut (Maranta arundinaceae Linn) Sebagai Bahan Pengikat Terhadap Sifat Fisik dan Kimia Tablet Parasetamol Sugiyono, Pipit Murdiyani dan Yulias Ninik W...........................................................32 - 37Perbedaan Pengaruh Lama Penyimpanan Larutan Susu Bubuk Full Cream dan Larutan Susu Kental Manis Terhadap Kadar Glukosa Risha Fillah Fithria, Agus Suprijono dan Maywan Hariono.......................................38 – 42ISSN : 1693-7899Volume 9 No 2 Desember 2012iiiPENGANTAR REDAKSI Assalamualaikum Wr. Wb. Alhamdulillah seiring dengan perjalanan Fakultas Farmasi Universitas Wahid Hasyim Semarang, Jurnal Ilmu Farmasi dan Farmasi Klinik (JIFFK) telah memasuki tahun ke-lima semenjak penerbitan perdana tahun 2004. Kami tetap berharap bahwa JIFFK dapat memberikan kontribusi bagi perkembangan ilmu farmasi dan farmasi klinik. Kami berharap bahwa JIFFK ini dapat digunakan sebagai wadah bagi para peneliti, akademisi dan pemerhati ilmu farmasi dan farmasi klinik untuk mempublikasikan hasil penelitian atau pemeikirannya. Demi menjaga eksistensi dan sustainabilitas JIFFK kami senantiasa memohon sumbangan tulisan atau artikel dari para peneliti. Kami selalu berusaha untuk dapat meningkatkan kualitas dari setiap penerbitan JIFFK ini, karena kami memiliki cita-cita supaya JIFFK dapat terakreditasi dari Dikti, DepDikNas-RI Akhir kata kami sampaikan terima kasih yang sebesar-besarnya kepada semua pihak yang telah membantu terlaksananya penerbitan ini. Kritik dan saran selalu kami nantikan dari pembaca sekalian demi perbaikan dan kemajuan JIFFK. Wassalamu'alaikum Wr. Wb. Semarang, Desember 2012 Hormat kami Redaks
PERBEDAAN HASIL EVALUASI PENGELOLAAN OBAT PUSKESMAS ISO DAN NON ISO KOTA SEMARANG TAHUN 2013
ABSTRACTEmptiness and breakage of drugs in health centers often leads to non ISO patient dissatisfaction, which might be due to non optimal medication management. This study was conducted to determine the differences of the evaluation result of drug management between ISO and non ISO health centers in Semarang at 2013.This type of research is analytic survey, with a sample of three of most visits ISO and non-ISO health centers and non-ISO. Retrospective data collection techniques along with free interview directed to drug manager. Materials and research tools were card stock, report morbidity data (LB1), recipes, and the inventory check. Data were evaluated every month used the indicators of the Ministry of Health of Indonesia in 2010 and were analyzed used independent sample t test and Mann Whitney.The result showed that there was difference of the evaluation result of drug management between ISO and non ISO health centers in Semarang at 2013 on indicator of available drugs item complies with DOEN (t <1.66691) and the percentage of generic drugs writing (t <1.66691).Keywords : Drug Management, ISO Health Centers, Non ISO Health Centers, Semarang Cit
Faktor-faktor yang mempengaruhi tingkat kepatuhan pengobatan ARV (Anti Retro Viral) pada ODHA (Orang dengan HIV/AIDS) di Rumah Sakit Umum Daerah Tugurejo dan Rumah Sakit Umum Panti Wilasa Citarum Semarang
Antihyperpigmentation Effect of The Combination of Turmeric (Curcuma domestica Val.) and Bitter Melon Leaves (Momordica Charantia L.) Ethanol Extracts on Guinea Pig Skin
PERBEDAAN EFEKTIVITAS ANTIBIOTIK PADA TERAPI DEMAM TIFOID DI PUSKESMAS BANCAK KABUPATEN SEMARANG TAHUN 2014
ABSTRACTThere are differences on the use of antibiotics on typhoid fever’s treatment. However, there was a research concluded that there were no differences between the efficacy of antibiotics on typhoid fever's therapy that shown as fever-free time and treatment duration. The purposes of this study are to determine the various antibiotics that used on typhoid fever’s treatment and to compare the efficacy of that antibiotic at Bancak Public Health Center Semarang regency. This study was an analytically survey research, with retrospective data collection from medical records, used purposive sampling method. The research sample was all adult patients’ typhoid fever hospitalization at Bancak Public Health Center Semarang regency. Data of antibiotic’s efficacy in fever-free time and treatment duration were analyzed with Kruskal-Wallis test. The result showed that the antibiotics used on typhoid fever’s treatment at Bancak Public Health Center Semarang regency were chloramphenicol, amoxicillin, cefotaxime, ceftriaxone, and ampicillin. Ceftriaxone was an antibiotic that provided the shortest fever's free-time and duration of treatment. However, there was no statistically significant difference between efficacy of that antibiotics at Bancak Public Health Center Semarang regency (p>0.05). Key words : Antibiotics efficacy, typhoid fever’s treatment, fever’s free-time, duration of treatment, Bancak Public Health Center
ANTIBACTERIAL AND ANTIACNE ACTIVITY OF n-HEXANE FRACTION OF ALFALFA HERB (Medicago sativa L.) ETHANOL EXTRACT IN VITRO AND ON RABBIT (Oryctolagus cuniculus)
Propionibacterium acnes (P. acnes) can cause inflammation of the polysebaceous glands and lead to acne. Flavonoids in alfalfa herb are thought to have antibacterial and antiinflammatory properties. Flavonoids can be absorbed into n-hexane solvents. This study aims to determine antibacterial activity of n-hexane fraction of alfalfa herb ethanol extract (nHFAH) against P. acnes in vitro, to calculate the total flavonoid levels in the fraction, and to determine antiacne activity of the fraction on rabbit. This study is an experimental study with post-test control group design. Extraction of alfalfa herb was done by maceration method using 70% ethanol and fractionated with n-hexane. Antibacterial activity test was carried out using disk diffusion with 5 series of concentrations (15%, 20%, 25%, 30% dan 35%), positive control (clindamycin 2 µg/disk) and negative control (DMSO 100%). Diameters of the inhibition area were analyzed statistically using a Kruskal Wallis test followed by Mann Withney test with 95% of confidence level. Rabbit back skin was shaved on 5 different areas (3x3 cm2/area). Induced with 0.2 mL of P. acnes suspension (3x109 CFU/mL) intradermal. Acne formed (24 hours) on all areas, then were treated with T1 (clindamycin 2%), T2 (DMSO 100%), T3 (nHFAH 20%), T4 (nHFAH 25%), T5 (nHFAH 30%). Erythema diameter reduction on day 9 was analyzed using one-way anova, continued by post hoc tukey with 95% of confidence level. Total nHFAH flavonoid levels were tested by colorimetric method using UVVis spectrophotometer at λ 429.5 nm. The results showed that nHFAH has antibacterial activity against P. acnes with an average value of diameter of inhibition area for each concentration were 7.30; 7.49; 7.75; 7.92 and 8.24 mm. nHFAH exhibits antiacne activity with the percentage for each concentration were 67.01%; 77.84% and 85.84% respectively. Total nHFAH flavonoid levels were 6.09 mgQE/ gram.Keywords: Alfafa herb, n-Hexane fraction, Propionibacterium acnes
THE ANTIHYPERPIGMENTATION EFFECT PARE LEAVES (Momordica charantia L.) ETHANOL EXTRACT ON GUINEA PIG (Cavia porcellus) SKIN
Hiperpigmentasi pada kulit telah terbukti dapat diatasi dengan ekstrak etanol daun pare (Momordica charantia L.) (EEDP) secara invitro. Penelitian ini bertujuan untuk membuktikan efek antihiperpigmentasi EEDP pada kulit Guinea pig (Cavia porcellus). Peneitian ini merupakan penelitian eksperimental dengan randomized matched post test only control group design. Proses ekstraksi menggunakan metode maserasi dengan cairan penyari etanol 70%. Dua puluh lima ekor Guinea pig dipapar sinar ultraviolet B 2 menit/hari selama 2 minggu, kemudian dibagi ke dalam 5 kelompok. Kelompok negatif diberi dimethyl sulfoxide (DMSO); kelompok positif diberi krim farma yang mengandung hydroquinone 4%, tretinoin 0,05%, and fluocinolone acetonide 0,01%; serta kelompok perlakuan diberi EEDP 200, 400, and 600 ppm. Seluruh perlakuan diberikan sekali sehari selama 2 minggu kemudian dilakukan biopsi jaringan. Uji histopatologi dilakukan menggunakan pewarnaan fontana-masion dan nuclear fast red. Perbedaan jumlah melanin pada seluruh kelompok dianalisa menggunakan uji Kruskal Wallis, diikuti dengan Mann-Whitney dengan taraf kepercayaan 95%. Data menunjukkan bahwa EEDP terbukti mempunyai efek antihiperpigmentasi dan seluruh kelompok EEDP mempunyai efek yang lebih baik dibanding dengan sediaan krim farma.Kata Kunci : Antihiperpigmentasi, Daun Pare, Guinea pig, Melanin
