16 research outputs found
Eenvoudige toetsmethode voor Havendammen
No full textIn Nederland zijn er vele havendammen die de primaire waterkeringen plaatselijk beschermen tegen grote golfaanval. Zelfs onder maatgevende omstandigheden zijn vele van deze dammen nog hoog genoeg om een belangrijk reducerende werking te hebben op de inkomende golven. Deze golfreducerende werking is met name zeer welkom als de toetsing van de waterkering alleen tot het resultaat ‘goed’ kan leiden dankzij deze invloed van de havendam, en een ‘onvoldoende’ zou opleveren zonder deze havendam. Uiteraard kan de invloed van de golfreducerende werking van havendammen alleen in rekening gebracht worden in de veiligheidstoetsing, als de havendam in stand blijft onder de maatgevende omstandigheden voor de toetsing. In dit verslag wordt de toetsmethodiek voor havendammen nader uitgewerkt. Het rapport beschrijft de toetsmethodiek voor de volgende elementen van havendammen: Voor havendammen met taluds: 1. Kruinhoogte (HT) 2. Damlichaam en voorland • Afschuiving voorland (AF) • Zettingsvloeiing voorland (ZV) • Afschuiving buitentalud (LB) • Macrostabiliteit binnenwaarts (STM) • Microstabiliteit (STU) 3. Bekleding (BK) • Afschuiving bekleding (BKA) • Toplaag bekleding (BKC) • Reststerkte bekleding (BKR) 4. Niet waterkerende elementen En voor verticale havendammen of verticale elementen in havendammen: 1. Hoogte (HT) 2. Stabiliteit constructie (STC) en voorland (VL
Campus y ciudad: la experiencia del Barcelona Knowledge Campus
No full textENG: This article presents a reflection on university campus and its relationship with the city, through topics and invariants of settlement
patterns and paradigmatic cases. Campus set different situations and ways of urban relationship, from urban location of early european
models, to suburban locationsof anglo-saxon models.
The article continues with a summary of professional and academic experience of Campus Diagonal in Barcelona, where the author
drafted a development plan. The objective of this plan is: to revitalize the campus and to link the city through integration strategies with
the surrounding tissue, incorporating complementary uses to the students. This campus belongs to the University of Barcelona (UB) and
the Polytechnic University of Catalonia (UPC), which were presented together under the identification of Knowledge Campus
Barcelona. BKC. It was also presented at the Campus of Excellence, opened by the Ministries of Education and Science and
Innovation in Spain, earning a prestigious distinction in November 2009. The article presents the most relevant aspects of urban and
architectural proposals of BKC, which is a ¨ cluster” of first-class training and reference. It also has the highest concentration of
knowledge in southern Europe, and novel and innovative teaching projects
University campus and urban engagement
No full textEl presente artículo presenta una reflexión sobre campus universitarios
y su relación con la ciudad a través de tópicos e invariantes de modelos
de asentamiento y casos paradigmáticos, donde se establecen distintas
situaciones y maneras de relación urbana, desde los modelos europeos
iniciales, de localización más nítidamente urbana, a modelos
anglosajones con localizaciones periurbanas.
Continúa con un resumen de la experiencia profesional y académica
en el Campus de la Diagonal de Barcelona, donde el autor redactó un
plan urbanístico con el objetivo de vitalizar el campus e integrarlo a la
ciudad a través de estrategias de conjunción con el tejido circundante,
incorporando usos complementarios a los universitarios. Este campus
está formado por la Universidad de Barcelona y la Universidad
Politécnica de Cataluña que se presentaron conjuntamente bajo la
identificación de “Barcelona Knowledge Campus. BKC” en la
convocatoria de Campus de Excelencia Internacional abierta por los
Ministerios de Educación y Ciencia e Innovación de España y
obtuvieron la prestigiosa distinción en noviembre de 2009.
Se exponen los aspectos más relevantes de las propuestas
urbanísticas y arquitectónicas del BKC que constituye un ¨cluster” de
formación de primer orden y referencia, y cuenta con la mayor
concentración de conocimiento del Sur de Europa y con novedosos
proyectos docentes y de innovación.This article presents a reflection on university campus and its
relationship with the city, through topics and invariants of
settlement patterns and paradigmatic cases. Campus set different
situations and ways of urban relationship, from urban location of
early european models, to suburban locations of anglo-saxon
models.
The article continues with a summary of professional and
academic experience of Campus Diagonal in Barcelona, where
the author drafted a development plan. The objective of this plan
is: to revitalize the campus and to link the city through
integration strategies with the surrounding tissue, incorporating
complementary uses to the students. This campus belongs to the
University of Barcelona (UB) and the Polytechnic University of
Catalonia (UPC), which were presented together under the
identification of "Knowledge Campus Barcelona. BKC". It was
also presented at the Campus of Excellence, opened by the
Ministries of Education and Science and Innovation in Spain,
earning a prestigious distinction in November 2009.
The article presents the most relevant aspects of urban and
architectural proposals of BKC, which is a ¨ cluster” of first-class
training and reference. It also has the highest concentration of
knowledge in southern Europe, and novel and innovative
teaching projects.Peer Reviewe
Campus y ciudad: la experiencia del Barcelona Knowledge Campus
No full textEl presente artículo presenta una reflexión sobre los campus y su relación con la ciudad, a través de tópicos e
invariantes de modelos de asentamiento y casos paradigmáticos. En estos campus se establecen distintas situaciones
y maneras de relación urbana, desde los modelos europeos iniciales, de localización más nítidamente urbana, a
modelos anglosajones con localizaciones periurbanas.
El artículo continúa con un resumen de la experiencia profesional y académica en el Campus de la Diagonal de
Barcelona, donde el autor redactó un plan urbanístico. El objetivo de este plan es: revitalizar el campus, y unirlo a la
ciudad, a través de estrategias de integracion con el tejido circundante, incorporando usos complementarios a los
universitarios. Este campus está formado por la Universidad de Barcelona y la Universidad Politécnica de Cataluña,
que se presentaron conjuntamente bajo la identificación de “Barcelona Knowledge Campus. BKC”. Fue
presentado en la convocatoria de Campus de Excelencia Internacional, abierta por los Ministerios de Educación y
Ciencia e Innovación de España, obteniendo la prestigiosa distinción en noviembre de 2009.
Se exponen los aspectos más relevantes de las propuestas urbanísticas y arquitectónicas del BKC, que constituye un
¨cluster” de formación de primer orden y referencia. Además, cuenta con la mayor concentración de conocimiento
del sur de Europa y con novedosos proyectos docentes y de innovación.ENG: This article presents a reflection on university campus and its relationship with the city, through topics and invariants of settlement
patterns and paradigmatic cases. Campus set different situations and ways of urban relationship, from urban location of early european
models, to suburban locationsof anglo-saxon models.
The article continues with a summary of professional and academic experience of Campus Diagonal in Barcelona, where the author
drafted a development plan. The objective of this plan is: to revitalize the campus and to link the city through integration strategies with
the surrounding tissue, incorporating complementary uses to the students. This campus belongs to the University of Barcelona (UB) and
the Polytechnic University of Catalonia (UPC), which were presented together under the identification of "Knowledge Campus
Barcelona. BKC". It was also presented at the Campus of Excellence, opened by the Ministries of Education and Science and
Innovation in Spain, earning a prestigious distinction in November 2009. The article presents the most relevant aspects of urban and
architectural proposals of BKC, which is a ¨ cluster” of first-class training and reference. It also has the highest concentration of
knowledge in southern Europe, and novel and innovative teaching projects.Peer Reviewe
Besouros indicadores (Coleoptera, Scarabaeinae) na avaliação de alteração ambiental em fragmentos de Mata Atlântica contíguos a cultivos de milho convencional e transgênico
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em EcologiaOs besouros da subfamília Scarabaeinae (Coleoptera: Scarabaeidae) são organismos extremamente importantes no funcionamento dos ecos-sistemas tropicais. A maioria das espécies se alimenta de fezes (copró-fagos), principalmente de mamíferos, ou de carcaças (necrófagos). Os escarabeíneos apresentam estruturas de comunidades que os tornam bons indicadores de diversidade. Algumas espécies possuem alta especificidade de habitat e são fortemente influenciadas pela fragmentação e perda de habitat. O presente trabalho visa estudar a composição e a estrutura de comunidades de besouros escarabeíneos que habitam áreas de fragmentos florestais nativos em meio a cultivos de milho convencional e de milho transgênico, com a finalidade de detectar possíveis impactos da fragmentação e do uso dos transgênicos em orga-nismos associados por meio da cadeia trófica. O estudo foi realizado na região de Campos Novos /SC onde foram estabelecidas vinte áreas a-mostrais de fragmentos de Mata Atlântica: dez áreas contíguas a cultivos de milho transgênico e dez áreas contíguas a cultivo de milho conven-cional. As coletas dos besouros escarabeíneos foram realizadas de forma intensiva durante fevereiro de 2011, com 200 armadilhas iscadas com fezes humanas (100) e com carne em decomposição (100). Para cada fragmento foram feitas medidas de complexidade ambiental, do tama-nho do fragmento e da distância aos demais fragmentos. Foram coleta-dos 1502 besouros de 33 espécies: 805 escarabeíneos de 27 espécies em 10 fragmentos adjacentes a milho convencional e 697 escarabeíneos de 27 espécies em 10 fragmentos adjacentes a milho transgênico. Houve diferenças na estrutura das comunidades de escarabeíneos provenientes dos dois tipos de ambientes. O tamanho, a distância e a complexidade ambiental dos fragmentos influenciaram, mas não explicaram as dife-renças da comunidade nos dois tipos de cultivo. O grupo funcional dos residentes teve grande importância nos fragmentos em meio ao milho transgênico e houve uma perda dos escavadores e rodadores nos frag-mentos em meio ao milho transgênico, o que pode estar alterando o papel dos escarabeíneos na regeneração da floresta. As espécies tunelei-ras Onthophagus tristis, Uroxys aff. terminalis, Ontherus sulcator e a roladora Canthon chalybaeus foram indicadoras de fragmentos em meio a milho convencional e Eurysternus francinae e Eurysternus parallelus, ambas residentes, foram indicadoras de fragmentos em meio ao milho transgênico. A diminuição dos besouros escavadores e rodadores nos fragmentos em meio ao milho transgênico poderá vir a afetar os serviços ecossistêmicos dos escarabeíneos, o que em longo prazo pode ter efeitos na ciclagem de nutrientes e na regeneração da florestaThe beetles of the subfamily Scarabaeinae (Coleoptera: Scarabaeidae) are important organisms that participate in the cycle of decomposition of tropical ecosystems. Most species feed on feces (dung) or carcasses (carrion) and are associated with animals that produce their food re-sources. Dung beetles are divided into three functional groups, depend-ing on the behavior of resource allocation during the reproduction: the rollers, tunnellers and dwellers. Some species of Scarabaeinae have high habitat specificity and are strongly influenced by habitat loss and frag-mentation. This study aimed to investigate the composition and structure of dung beetle communities (Coleoptera: Scarabaeidae: Scarabaeinae) inhabiting areas of forest fragments within conventional and transgenic maize plantations; the purpose was to detect possible impacts of the use of transgenic in non-target organisms associated through the food chain. The study was conducted in the region of Campos Novos/SC where they were established twenty sample areas of Atlantic Forest fragments. Samplings of dung beetles were conducted with 200 traps "pit-fall," 100 baited with human feces and 100 baited with carrion. In each fragment were also made measurements of fragment size and environmental com-plexity. Were collected 1502 dung beetles, divided into six tribes, 12 genera and 33 species: 805 dung beetles of 27 species in 10 fragments adjacent to the conventional maize and 697 dung beetles of 27 species in 10 fragments adjacent to transgenic maize. With the Levins index 11 species were classified as coprophagous, ten generalists and two necrophagous. There were significant differences in the community structure of the two types of fragments. The size, distance between fragments and environmental complexity of the fragments influenced, but did not explain the differences of the community in both types of crops. The functional group dwellers was more representative in the fragments in the midst of transgenic maize with Eurysternus francinae and Eurysternus parallelus (dwellers) was indicator in the fragments of transgenic maize and Onthophagus tristis, Uroxys aff. terminalis, Ontherus sulcator (tunnellers) and Canthon chalybaeus (roller) were indicator in fragments in the midst of conventional maize. The decrease of the tunnellers and rollers in fragments in the midst of the transgenic maize result in loss of ecosystem services and their role in nutrient cy-cling and forest regeneration may be being modificate
Identification and characterization of complexes of cationic and anionic surfactants at equal charge ratio
No full textThe objective of this study was to investigate the complex structures formed of cationic and anionic surfactants. X-ray diffraction, 1H-NMR, FTIR and LC-MS methods have been applied in the current study. A novel crystalline complex, consisting of chlorhexidine-dodecyl sulfate, was obtained after aging at 60 °C for three weeks. The structure was solved by single crystal X-ray diffraction. The molar ratio of chlorhexidine and dodecyl sulfate was 1:2, indicating a complex between a divalent cation and two nonvalent anions. In addition, the impact of phosphate, pyrophosphate and triphosphate anions on the stability and solubility of the complex was monitored by observing precipitate. The complex was further examined by LC-MS method with a direct infusion. For comparison, other surfactants were studied: including anionic surfactant sodium lauroyl methyl taurate (SLMT) and two cationic surfactants, cetylpyridinium chloride (CPC) and benzalkonium chloride (BKC). ESI-MS enabled us to study both positively and negatively charged clusters.M.S.T.Includes bibliographical reference
Loss of secretin results in systemic and pulmonary hypertension with cardiopulmonary pathologies in mice
No full textMore than 1 billion people globally are suffering from hypertension, which is a long-term incurable medical condition that can further lead to dangerous complications and death if left untreated. In earlier studies, the brain-gut peptide secretin (SCT) was found to be able to control blood pressure by its cardiovascular and pulmonary effects. For example, serum SCT in patients with congestive heart failure was one-third of the normal level. These observations strongly suggest that SCT has a causal role in blood pressure control, and in this report, we used constitutive SCT knockout (SCT−/−) mice and control C57BL/6N mice to investigate differences in the morphology, function, underlying mechanisms and response to SCT treatment. We found that SCT−/− mice suffer from systemic and pulmonary hypertension with increased fibrosis in the lungs and heart. Small airway remodelling and pulmonary inflammation were also found in SCT−/− mice. Serum NO and VEGF levels were reduced and plasma aldosterone levels were increased in SCT−/− mice. Elevated cardiac aldosterone and decreased VEGF in the lungs were observed in the SCT−/− mice. More interestingly, SCT replacement in SCT−/− mice could prevent the development of heart and lung pathologies compared to the untreated group. Taken together, we comprehensively demonstrated the critical role of SCT in the cardiovascular and pulmonary systems and provide new insight into the potential role of SCT in the pathological development of cardiopulmonary and cardiovascular diseases. © 2019, The Author(s).published_or_final_versio
Expression and transcriptional regulation of the GnRH receptor gene in human neuronal cells
No full textGnRH, acts via the GnRH receptor (GnRHR), plays a pivotal role in human reproduction by stimulating the synthesis and secretion of gonadotropins from pituitary gonadotropes. Studies have also suggested that it has other extra-pituitary functions. To date, the transcriptional regulation of human GnRHR gene in the brain remains largely unknown. Recently, the human cerebellar medulloblastoma cell line TE-671 is found to express GnRH. We report here for the first time that GnRHR is also expressed in this neuronal cell line. Treatment with GnRHR agonist stimulated the phosphorylation of both ERK1/2 and JNK in the cells. Moreover, transient transfection of various human GnRHR promoter-luciferase constructs into the cells identified an upstream promoter region located between -2197 and -1018. Important cis-acting regulatory elements were found at -1300/ -1018 and -2197/- 1900, as deletion of either region caused a dramatic decrease in the promoter activity. An upstream GnRHR promoter element was identified to be important for basal transcription in the human neuronal TE-671 cells, in contrast to the previous finding that a downstream promoter is responsible for the gonadotrope-specific expression. Furthermore, we showed that antide (GnRHR antagonist) significantly stimulated the GnRHR promoter activity and inhibition of protein kinase C (PKC) pathway by staurosporine could also up-regulate the promoter activity in dose- and time-dependent manners. Taken together, these data suggest that activation of the GnRHR by interacting with GnRH may transcriptionally down-regulate itself via the PKC pathway in human neuronal cells. © The Author 2005. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved.link_to_subscribed_fulltex
Dichotomius (Cephagonus) filgueirasi Nunes & Vaz-de-Mello 2019, new species
No full text2.5.: Dichotomius (Cephagonus) filgueirasi new species (Figure 24) Diagnosis. distinguished from the other species in the group by the following combination of characteristics: males cephalic carina strongly transverseı larger than tallerı rounded apically; anterior portion of the pronotum bearing strongı coarse puncturesı widely emarginated and excavated anteriorly (as in D. punctulatipennis of bicuspis group); lateral margins of the pronotum serrate (as in D. baiano and D. fernandosilvai of fissus group); males ’ pronotal disc with four lobes at anterior portion and 5) elytra lacking microsculpture. ● HOLOTYPEı male: BRASIL: Alagoas: Ibateguara. Aquidabã. Banana. 16-iii-2008. BKC Filgueiras [at CEMT]. ● PARATYPES: same data of Holotype [8 ƋƋı 1 ♀ at CEMT]; no municipality. vi-1998 [1 Ƌı 2 ♀♀ at CEMT]; Paraíba: Mamanguape. REBIO Mamanguape. 6³41 ’ Sı 35 ³10 ʹ W. Pitfall. iii-2002. MIM Hernandéz [2 ƋƋ at CEMT]; same data but 17-ii-1999. A Endres [2 ƋƋ at CEMT]; Pernambuco: Recife. Campus UFPE [1 Ƌ at CEMT]. Description (holotype). BL: 22 mmı PW: 13 mm. Colour: black. Head: fronto-clypeal surface smooth. Genal surface wrinkled with striations and fine punctures. Inter-ocular surface with coarse punctures. Gena borders straight. Cephalic carina larger than tallerı rounded at apexı with striations on its base. Pronotum: borders serrate with scattered dense setae. Pronotal disc shinyı lacking punctuationı anterior portion with four lobesı a pair of them placed posteriorly and another pair placed more anteriorly. Anterior portion widely excavated and emarginated and filled with denseı coarse punctures. Posterior margin with two rows of ocellate punctures. Metasternum: sides and anterior portion of the anterior lobe covered by dense red setae. Setigerous punctures equally spacedı where present. Elytra: striae weakly impressed with weak punctures. Punctures separated by twice their diameter. Interstriae flatı lacking microsculpture. Abdomen: with clusters of 1 – 5 red setae at the sides of the ventrites. Punctuation at the anterior margin of the ventrites interrupted medially. Aedeagus (Figure 24 (d-f)): parameraı apexes rounded dorsallyı convergent; longitudinal excavation taking 2/3 of paramera length; basal excavations wideı carinate; Laterallyı with a subtle declivity towards apex. Base excavated ventrallyı constrained at mid-point; subgenital plate rounded at the base and widely emarginate at apex. Morphological variation. male BL: 16 – 22 mmı PW: 9 – 13 mm. Smaller males have a conical cephalic carina and lack pronotal lobes and knobs (or have it less developed) at anterior end of the disc. Females BL: 18 − 20ı PW: 10 – 11 mm and are distinguishable from the males by the following: Head: fronto-clypeal surface transversely wrinkled. Cephalic carina transversalı forming a weak pair of tubercles. Pronotum: punctures coarser than those of malesı posterior margin with two defined rows of elliptical punctuates. Pronotal borders strongly serrated. Elytra: striae deeply impressedı punctures separated by twice their diameter. Abdomen: sixth ventrite bearing a pair of triangular projections reaching the apical margin of the pygidium. Distribution. Brazilian Atlantic forest in the states of Alagoas and Pernambuco (Figure 17). Etymology. named after Dr. Bruno Karol Cordeiro Filgueiras (Universidade Federal de Pernambucoı Brasil)ı who collected the holotype.Published as part of Nunes, Rafael V. & Vaz-de-Mello, Fernando Z., 2019, Taxonomic revision of Dichotomius (Cephagonus) Luederwaldt 1929 and the taxonomic status of remaining Dichotomius Hope 1838 subgenera (Coleoptera: Scarabaeidae: Scarabaeinae: Dichotomiini), pp. 2231-2351 in Journal of Natural History 53 (37) on pages 2300-2301, DOI: 10.1080/00222933.2019.1692088, http://zenodo.org/record/366551
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Correction: Emergence of two distinct phase transitions in monolayer CoSe2 on graphene
No full textFollowing publication of the original article [1], the author identified an error in Graphical Abstract and updated Acknowledgment section. In Graphical abstract, there is a type on the unit EB(eV) which has been updated with this correction. The work supported by MOLIT [Innovative Talent Education Program for Smart City] has been included in Acknowledgment statement. This work is supported by National Research Foundation (NRF) grants funded by the Korean government (NRF-2019R1A6A1A11053838, NRF-2020R1A2C200373211, NRF-2021R1A6A3A14040322, RS-2023-00220471, RS-2023-00284081, RS-2023-00280346, RS-2023-00258359), [Innovative Talent Education Program for Smart City] by MOLIT, and Semiconductor R&D Support Project through the Gangwon Technopark (GWTP) funded by Gangwon Province (No. GWTP 2023-027). BKC was supported in part by an ALS Collaborative Postdoctoral Fellowship. This research used resources of the Advanced Light Source, which is a DOE Office of Science User Facility under contract no. DE-AC02-05CH11231. Experiments at PLS-II were supported in part by MSICT and POSTECH. The original article has been corrected
