107 research outputs found
Migliorare la sostenibilità territoriale - strutture di analisi spaziale per indagare l'espressione dei servizi ecosistemici
The current doctoral research has been focused on Ecosystem Services (ES)-based formal and analytical approaches, to support territorial sustainability.
Addressing the above-mentioned issue allowed me to explore ES’s role in contributing to the global sustainable development goals, and provide spatially explicit methodologies to support ES assessment on local and large territorial scales. Thanks to the results to be discussed, this work has been part of various strategically important local, national, and international projects. At the local scale, the main outcomes of the doctoral research are currently supporting the municipality of L’Aquila (central Italy) to reframe its urban boundaries. At a higher scale, several elaborations have been employed in the SICURA project, to define strategies for integrated risk management in urban areas. ES-related methodologies and elaborations are also supporting several actions of the LIFE IMAGINE project. LIFE IMAGINE aims to create an integrated management system to achieve the conservation objectives of the EU Habitats and Birds directives in the Umbria region (central Italy) in an economically and technically sustainable way. The research also assisted the Sost.EN.&Re project, aimed at supporting the implementation, in central Italy, of the National Strategy for Sustainable Development. Finally, several research applications are currently employed in the newly launched Horizon 2020 project ”U CAN”, whose objective is to provide ad hoc analyses to align Ukrainian cities with European climate policies. I hope that the research results will contribute to enriching the existing ES knowledge in local and large territorial scales, towards the achievement of sustainable development
Supporting Sustainable Development Goals through Regulation and Maintenance Ecosystem Services
Sustainable development goals (SDGs) have a huge impact on global policies. Contextually, the concept of ecosystem services (ESs) naturally relies on the importance of integrating human activities into a framework in which ecosystems play a fundamental role in supporting upcoming societies. Introducing ESs in the process of SDG evaluation can be useful to facilitate their achievement through national and local planning policies. Nevertheless, this aspect is still poorly addressed. In the present study, an in-depth analysis has been conducted, to associate regulation and maintenance ecosystem services (ReMESs) with the SDGs set by the 2030 Agenda. Based on the available scientific literature, ReMESs have been linked to the SDGs and SDG targets. Specific attention has been paid to deepening linkages with the SDG targets that explicitly address the introduction of ecosystem and biodiversity values into national and local planning. Finally, SDG evaluation has been further investigated, linking the SDG targets to the statistical measures proposed by the Inter-agency and Expert Group on SDGs (UN-IAEG-SDGs). This last step focused on the Italian context, according to the indicators provided by the National Institute of Statistics. The results show that ReMESs are linked to 8 out of 17 SDGs (47%). Connections decrease when considering the SDG targets (20%) and the national statistical measures (18%). It also emerges that some targets, although being connected to ReMESs, do not have the right indicators to be quantified. Ecosystem services prove to be a valid element through which modern sustainable development goals can be accomplished. This study, which highlights several gaps to be filled, wants to offer valuable help in evaluating SDGs and their implementation through ReMESs
Fostering Climate Neutrality: The Role of the U CAN Project in Sustainable Planning of Ukrainian Territories
The European Union (EU) is one of the leading global actors in addressing climate change through ambitious goals such as the ones in the European Green Deal (EGD) and the Nature Restoration Law (NRL). These initiatives set clear targets for climate resilience and sustainability across member states. Within this context, the fifth work package of the Horizon 'Ukraine towards CArbon Neutrality' (U_CAN) project explicitly addresses the Modernisation and standardisation of technologies and practices. This paper outlines the conceptual and methodological contributions provided within the 5.4.4 deliverable, aimed at offering spatially explicit tools and methodologies to support local Ukrainian authorities in developing sustainable and resilient land planning policies, detailing the technical approaches employed. Remote sensing and local data, AI-related methodologies, spatially explicit frameworks and software will be at the core of the activities envisaged in the 5.4 task of the U_CAN project. The main implications of the expected outcomes will be, among all, the contextualization of the environmental and human features both at large and local landscape scales, as well as the support to the definition of planning standards and guidelines
Dissecting the physiology and pathophysiology of glucagon-like peptide-1
Copyright © 2018 Paternoster and Falasca. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. An aging world population exposed to a sedentary life style is currently plagued by chronic metabolic diseases, such as type-2 diabetes, that are spreading worldwide at an unprecedented rate. One of the most promising pharmacological approaches for the management of type 2 diabetes takes advantage of the peptide hormone glucagon-like peptide-1 (GLP-1) under the form of protease resistant mimetics, and DPP-IV inhibitors. Despite the improved quality of life, long-term treatments with these new classes of drugs are riddled with serious and life-threatening side-effects, with no overall cure of the disease. New evidence is shedding more light over the complex physiology of GLP-1 in health and metabolic diseases. Herein, we discuss the most recent advancements in the biology of gut receptors known to induce the secretion of GLP-1, to bridge the multiple gaps into our understanding of its physiology and pathology
Architettura con le ali. Copertura ad ali di gabbiano e vetro strutturale nel progetto in corso d'opera per le Nuove Segreterie del campus universitario di Pescara.
Il contributo illustra i caratteri di un componente strategico del processo di trasformazione in atto nella città di Pescara. L'edificio realizzato per accogliere gli uffici di segreteria è concepito, mediante l'utilizzo di tecniche costruttive innovative, come spazio ad alto grado di flessibilità interna adattivo al variare dei fabbisogni, nonchè come architettura d'interfaccia tra il polo universitario e la città in corrispondenza di uno dei principali nodi urbani
Ampliamento polo universitario viale Pindaro. Edificio delle nuove segreterie
Il contributo illustra i caratteri di un componente strategico del processo di trasformazione in atto nella città di Pescara. L'edificio realizzato per accogliere gli uffici di segreteria è concepito, mediante l'utilizzo di tecniche costruttive innovative, come spazio ad alto grado di flessibilità interna adattivo al variare dei fabbisogni, nonchè come architettura d'interfaccia tra il polo universitario e la città in corrispondenza di uno dei principali nodi urbani
Traiettorie applicative e metodologiche del Contratto di Fiume tra territorio e città: trasversalità e multiscalarità.
Aquatic environments, fragile and vulnerable, are often compromised by phenomena such as soil artificialization, urban growth, and pollution. On one hand rivers are impacted by human activities on the territory; on the other, their degradation exacerbates the often-disastrous effects of climate change in urbanized areas. The River Contract (CdF) increasingly emerges as a strategic tool, addressing the shortcomings of outdated and rigid territorial planning to tackle global challenges through a local approach. It promotes a negotiated (and coordinated) model that integrates territorial, environmental, social, and economic aspects. Among the key innovative elements incorporated by CdFs are the recognition of Ecosystem Services, Nature-Based Solutions, and their contextualization within territorial and urban frameworks
Discretization of the Urban and Non-Urban Shape: Unsupervised Machine Learning Techniques for Territorial Planning
One of the goals of the scientific community is to equip the discipline of spatial planning with efficient tools to handle huge amounts of data. In this sense, unsupervised machine learning techniques (UMLT) can help overcome this obstacle to further the study of spatial dynamics. New machine-learning-based technologies make it possible to simulate the development of urban spatial dynamics and how they may interact with ecosystem services provided by nature. Modeling information derived from various land cover datasets, satellite earth observation and open resources such as Volunteered Geographic Information (VGI) represent a key structural step for geospatial support for land use planning. Sustainability is certainly one of the paradigms on which planning and the study of past, present and future spatial dynamics must be based. Topics such as Urban Ecosystem Services have assumed such importance that they have become a prerogative on which to guide the administration in the difficult process of transformation, taking place not only in the urban context, but also in the peri-urban one. In this paper, we present an approach aimed at analyzing the performance of clustering methods to define a standardized system for spatial planning analysis and the study of associated dynamics. The methodology built ad hoc in this research was tested in the spatial context of the city of L’Aquila (Abruzzo, Italy) to identify the urbanized and non-urbanized area with a standardized and automatic method
Class II Phosphoinositide 3-Kinases Contribute to Endothelial Cells Morphogenesis
PMCID: PMC3539993This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
De-sealing, recupero del suolo e (ri)attivazione dei Servizi Ecosistemici: il ruolo degli interventi di rigenerazione delle grandi aree dismesse nei territori urbani
The recovery of soil and its characteristics before soil sealing processes represents a complex issue still not adequately addressed in urban regeneration thinking and application. In a national context where the reform of knowledge and discipline in town planning has yet to find an agreement for its transposition into planning instruments, the experiences of reconversion of large areas often follow autonomous logic. In these cases, opportunity and occasionality are frequently the drivers that delineate the entire urban planning process. Starting from the transformation process that radically reconfigured the former Michelin area in Trento, a reflection is proposed on the actions for the redevelopment of city spaces and, in particular, on those interested in using soil de-sealing to favor the formation of new green areas and Nature-based Solutions (NbS). The paper, therefore, dwells on the description of the planning and implementation process proposed for the former Michelin, and how the use of NbS techniques has emerged as an opportunity to activate or restore certain Ecosystem Services. In addition, the paper proposes a reflection on how new ES assessment techniques can contribute, at various scales, to critically analyzing the results produced by urban regeneration interventions.
Il recupero del suolo e delle sue caratteristiche precedenti ai processi di impermeabilizzazione rappresenta un tema complesso che non ha ancora incontrato un’adeguata trattazione nella riflessione e applicazione in materia di rigenerazione urbana. In un contesto nazionale dove la riforma dei saperi e della disciplina in campo urbanistico deve ancora trovare un accordo per la sua traduzione negli strumenti di pianificazione, le esperienze di riconversione di ambiti di grande dimensione seguono spesso logiche autonome. In questi casi opportunità e occasionalità sono di frequente i driver che delineano l’intero percorso urbanistico. Partendo dal processo di trasformazione che ha riconfigurato radicalmente l’area dell’ex Michelin di Trento, si propone una riflessione sulle azioni per la riqualificazione degli spazi delle città e, in particolare, su quelle interessate ad utilizzare la de-impermeabilizzazione dei suoli per favorire la formazione di nuove aree verdi e Nature-based Solutions (NbS). Il lavoro si sofferma pertanto sulla restituzione del processo di pianificazione e attuazione proposto per l’ex Michelin e su come il ricorso a tecniche ascrivibili a NbS si sia configurato come l’occasione per attivare o ripristinare alcuni Servizi Ecosistemici. Inoltre, il lavoro propone uno spunto di riflessione su come le nuove tecniche di valutazione dei SE possano contribuire, a varie scale, ad analizzare criticamente i risultati prodotti dagli interventi di rigenerazione urbana
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