15,461 research outputs found
No. 85 -- Report of R. C. Fay, local agent at Penn's Cove
No full textReport to M. T. SimmonsPenn's Cove Location, June 30, 1858Alternative tribal name forms: Sno-dom-ish, Ke-ka-alons, Scho-nam-ish, Snoqualmie, Ski-quam-is
Una interpretación de a-ka-na-jo ( a3-ka-na-jo)
No full textThe author studies the word a-ka-na-jo in the PY Cn 328 tablet and taking into account some factors she proposes αγναιος as the reading of this word.The author studies the word a-ka-na-jo in the PY Cn 328 tablet and taking into account some factors she proposes αγναιος as the reading of this word
Environmental influences over the last 16 ka on compound-specific δ13C variations of leaf wax n-alkanes in the Hani peat deposit from northeast China
No full textCompound-specific carbon isotope ratios (δ13C) of leaf wax n-alkanes (C21-C33 odd carbon numbered n-alkanes) were measured in the Hani peat sequence from northeast China. These data were compared with lipid biomarker compositions to assess changes in local vegetation and paleoclimate for the last 16 ka The δ13C values of n-alkanes range between -36.6 and -30.7‰, showing that the compounds originate from C3 plants. Much larger variations (∼5.4‰) in the n-alkane δ13C values than those of atmospheric CO2 during the last 16 ka (< 0.5‰) indicate that the isotopic values were affected by environmental factors in addition to the postglacial δ13C variations in the atmospheric reservoir. The stratigraphic records of δ13C reveal decoupled fluctuations among the individual n-alkanes, particularly between 15.5 to 11.4 ka. Synchronous excursions in the δ13C offsets among individual n-alkanes (Δδ13C) and lipid biomarker paleoplant proxies (Paq, and C23/C31 and C27/C31) from 14.9 to 13.2 ka and 12.7 to 11.6 ka suggest that vegetational changes are the most likely causes for the decoupled δ13C variations. Parallel fluctuations of the δ13C values of terrestrial higher plant-derived C29 and C31 n-alkanes and the n-alkane average chain-length (ACL) from 11 to 6 ka indicate that the δ13C variations responded to net evaporation changes. Negative shifts in the n-alkane δ13C values coinciding with the ACL decreases at 10.5-9.3 ka and 8.1 ka indicate the short-term onset and fluctuations of the summer monsoon strength in eastern China during the early Holocene
NRF2 and chemoprevention: signaling, epigenetics and role in intestinal carcinogensis
No full textPrevention is better than cure. The carcinogenesis could take as long as 20 to 30 years to develop from initiated cells to malignant tumor, therefore providing us various opportunities to prevent the appearance of tumors with the use of chemopreventive compounds in the early stage. Chemoprevention becomes an increasing important concept and has led to the intense research about the mechanisms of actions of various chemopreventive compounds. They can be generally classified into blocking agents and suppressing agents. The chemopreventive compounds usually prevent or slow progression of cancer by maintaining a low oxidative stress and inflammatory environment in cells. This is brought about by the activation of Nrf2, the key protein being investigated in our lab. In this dissertation, I will be discussing the use of compounds as suppressing agents and blocking agents, how compounds activates Nrf2 signaling, how novel Nrf2 interaction partner IQGAP1 mediates Nrf2-Keap1 signaling axis, how expression level of Nrf2 could be regulated epigenetically, apart from the well-known post-translational control by Keap1-Ubiquitinase-Protesome axis and finally how loss of Nrf2 could enhance intestinal tumorigenesis in Apc(min/+) mice.Ph.D.Includes bibliographical referencesIncludes vitaby Ka Lung Cheun
Nearby fibroblasts' response to multiple acupuncture needle revolutions on fibroblast populated collagen gels
No full textAcupuncture is an ancient Chinese healing practice, and an alternative therapy for alleviating pain and chronic disorders. For over twenty years, research is trying to understand the mechanisms that lead to its therapeutic effect. Our laboratory investigates the cellular and molecular events in the connective tissue that occur by acupuncture needling. An in vitro assay was developed to evaluate some of the potential contributors to acupuncture’s effects using a cellular collagen gel as a loose connective tissue mimic. It was hypothesized besides immediate changes to cells under mechanical loading from an acupuncture needle, there were chemical factors released to nearby cells in acupuncture. This thesis investigates whether mechanically stimulating collagen gels with fibroblasts at different revolutions would release chemical factors to nearby fibroblasts where flow cytometry was used to observe cell proliferation as an indicator. Results reveal mechanically stimulating cellular collagen gels at different revolutions does not cause any changes in cell proliferation to nearby cells. However, dead stained mechanically stimulated cellular collagen gels showed cell death occurs around the acupuncture needle. It is possible there were no effects in cell proliferation because when a cellular collagen gel was needle manipulated, some chemical factors were released into the nearby cells. Then as needle manipulation increased, more chemical factors were released, but restricted by the larger amount of cell death around the needle from the increasing rotation.M.S.Includes bibliographical referencesby Ka Po Ch
Kuzey Anadolu Fay Zonu (Türkiye) boyunca Niksar çek-ayır havzasında kıta içi kuvaterner yaşlı volkanizma
No full textKuzey Anadolu Fay Zonu’nun doğu segmentleri üzerinde yer alan Niksar Havzası 1939 ve 1942 depremleri ile ilişkili birbirine paralel olmayan iki ana fay ile sınırlı, genç sigmoidal bir çek-ayır havzadır. Fay geometrisi havzanın düzensiz DKD kenarında karmaşıktır. Burada genç Pliyo–Kuvaterner yaşlı volkanik kayaçlar havza sedimanlarını da kesen doğrultu-atımlı fay çiftleri boyunca yüzeye çıkmaktadır. Niksar havzası civarında yüzeyleyen volkanik kayaçlar yüksek hassasiyetli K-Ar yöntemiyle yaşlandırılmış olup, yaşlar 542 ± 9 ka ve 567 ± 9 ka arasındadır. Lavlar çoğunlukla alkalin (sodyumca zengin) özelliktedir ve bazaltik trakiandezit (Mujearit) and trakiandezit (benmorit) ile az oranda sub-alkalin bileşimli dasit, andezit, riyodasit ve riyolitten oluşmaktadır. Bazaltik ve felsik lavlar arasında büyük bir bileşimsel boşluk olmasına rağmen, ana ve iz element dağılımları hem bazaltik hem de felsik lavların eşkökenli olduğunu gösterir. Ana oksitlerin ile iz elementlerin bolluğu sistematik olarak bu bileşimsel dağılım içinde çeşitlilik sunmaktadır. Gözlenen fazlardaki fraksiyonel kristalleşme ortaç ve ileri derecede gelişmiş ürünlerdeki farklılığı ifade etmektedir. Derinde bazaltlardaki amfibol fraksiyonelleşmesi silikatca doygun bir yönelime neden olurken, alkali feldispat fraksiyonelleşmesi ise kristalleşmenin son evrelerini işaret etmektedir. Belirgin kabuksal kirlenme gelişmiş magma içerisinde oluşmuştur, fakat kirlenme genellikle bunların bazaltik ürünlerinde çok az yada hiç yoktur. Alkali bazaltik kayaçlar OIB (okyanus adası bazaltlar) benzeri, LILE, HFSE, LRE zenginleşmesi ve az miktarda ilksel manto değerlerine nazaran azalma gösteren HREE değerleriyle karakterize edilen iz element dağılımları sunmaktadır. Tüm jeokimyasal dağılımlar farklı derecelerdeki kısmi ergime olayının birleşik etkisini, fraksiyonel kristalleşmeyi ve değişik derecelerde kabuksal kirlenmeyi göstermektedir.The Niksar Basin is sited along the eastern segment of the North Anatolian Fault Zone in Turkey. It is a young sigmoidal pull-apart basin bordered by two non-parallel master faults associated with earthquakes in 1939 and 1942. The fault geometry along the irregular ENE margin of the basin is complex where young Plio&#8211;Quaternary volcanic rocks reach the surface along pairs of steep strike-slip faults which cut the basin sediments. The volcanic rocks around the Niksar Basin have been dated by high precision K-Ar dating and the ages range between 542 ± 9 ka and 567 ± 9 ka. The lavas are mainly alkaline (sodium dominated) in nature and include basaltic trachandesite (mugearite) and trachyandesite (benmoreite) with minor sub-alkaline compositions of dacitic andesite, rhyodacite and rhyolite. Despite the large compositional gap between basaltic and felsic lavas, major and trace element distributions indicate that both the basaltic and felsic lavas are cogenetic. Abundances of major oxides and trace elements vary systematically through this compositional spectrum. Fractional crystallization of the observed phases accounts for the diversity of intermediate and evolved products. Amphibole fractionation in basalts at depth causes the trend towards silica saturation while alkali feldspar fractionation dominates the final stages of crystallization. Significant crustal contamination has occured in the evolved magmas but contamination is generally minimal or absent in their basaltic parents. Alkaline basaltic rocks have OIB (ocean island basalt) like trace element patterns characterized by enrichment in LILE, HFSE, LREE and slight depletion in HREE relative to primitive mantle values. Overall geochemical variations indicate the combined effects of different degrees of partial melting, fractional crystallization and variable degrees of crustal contamination
Duan wei xia mu xie lei de xin xing he nei DNA fen zi xi tong biao ji zhi jian ding
No full textLeung Ka Chun.Thesis M.Phil. Chinese University of Hong Kong 2013.Includes bibliographical references (leaves 100-110).Abstracts also in Chinese.Title from PDF title page (viewed on 21, September, 2016).Leung Ka Chun
San zhong chao jian dai teng hu dui gao wen de sheng li fan ying ji zhuan lu ti yan jiu
No full textWong, Ka Wing Karen.Thesis M.Phil. Chinese University of Hong Kong 2014.Includes bibliographical references (leaves 143-157).Abstracts also in Chinese.Title from PDF title page (viewed on 30, November, 2016).Wong, Ka Wing Karen
The application of S-band polarimetric radar measurements to Ka-band attenuation prediction
No full textIn September 1993, the National Aeronautics and Space Administration's Advanced Communications Technology Satellite (ACTS) was deployed into a geostationary orbit near 100° W longitude. The ACTS satellite employs two Ka-band beacons, one at 20.185 GHz and another at 27.505 GHz. Impairments due to rain attenuation and tropospheric scintillations will significantly affect new technologies for this spectrum. Heavy rain at Ka-band can easily produce 30 dB of attenuation along the propagation path. Propagation experiments being conducted in seven different climatic zones involve multiyear attenuation measurements along the satellite-earth slant path. Measurements in the B2 climatic zone are made with an ACTS propagation terminal located in northeast Colorado. In order to gain more understanding about the physical processes that are responsible for Ka-band attenuation, the Colorado State University CHILL S-band polarimetric radar is used to take radar measurements along the slant path. The Colorado Front Range experiences a variety of weather conditions throughout the year ranging from upslope rain conditions to winter storms. Four such events measured along the slant path are illustrated in this paper. They include two convective cases and two "bright-band" cases. The S-band polarimetric radar data is used to initialize radar-based attenuation-prediction models, which are applied to the four precipitation events described. The comparisons of predicted attenuation to measured attenuation are quite good. It was also found during the course of the experiment that water droplets standing on the antenna surface can cause appreciable attenuation at Ka-band frequencies. That finding needs to be recognized in future model development and statistical analysis
Amritlal Nagar Ke Upannyas \u27Manas Ka Hans\u27 Ka Vaistichya
No full textThe entire life of Tulsidas of \u27Manas Ka Hans\u27 is disturbed by the ambushes of struggles and achieves the peak of faith. Goswami Tulsidas\u27s literature, his description and grand form are one with the unshakable land of \u27faith\u27, this is universally accepted. The prevailing legends, available evidence and the author\u27s own contemplation made Tulsi Das a living legend and scholar of public life. Artistic, Sushtu, Ragakrit, Udantakaran, Darun, Knowledge-Making, Past-oriented, Story-telling, Implore, Akhyata, Scholarly, Gharsthika, Emotionless, Philanthropic
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