39 research outputs found
Comment on “The neuroinvasive potential of SARS‐CoV‐2 may play a role in the respiratory failure of COVID‐19 patients”
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NEUROPSYCHOLOGICAL APPROACH OF FACTORS AGGRAVATING THE READING LEARNING DIFFICULTIES AMONG MOROCCAN ARABIC-SPEAKING STUDENTS WITH DEVELOPMENTAL DYSLEXIA PROFILE
No full textDyslexia is the most common learning disability in school and the most devastating in terms of academic performance. In interaction with the socio-cultural environment, several and various factors can aggravate the difficulties of reader acquisition in dyslexic children. Identifying these factors and interpreting them according to the neuropsychological approach, in the Moroccan context, was the objective of this study Socio-economic data was collected from 626 children, aged 9 to 15 years with an average age of 11,95 years, enrolled in public educational establishments in the Beni Mellal-Khenifra region, located in central Mo- rocco. Among all the participants, 41 had a profile of dyslexia, 13 of whom had reading attitudes evoking "severe dyslexia". Subjects underwent a cognitive assessment. the others were normal-readers and classified as good readers (n=481) and weak readers (n=104). To follow our purpose, we have determined socio-cultural and cognitive variables that may discriminate between students in the "severely dyslexic" group and their "dyslexic" peers. The performance gap was significant in favor of "dyslexic" students in the reading test of pseudowords, rapid naming of images, and the deletion of the initial phoneme. These data reinforce the hypothesis that the phonological deficit is at the root of developmental dyslexia. On the socio-cultural domain, the results showed that preschool attendance and early exposure to written language activity discriminate the participants with a "severe dyslexia" profile from their peers in the "dyslexic" group. We believe that these two factors were responsible for the moderate intensity of the disorder observed in the "dyslexic" group. Our study also showed that bilingualism raises the degree of learning reading difficulties among students with this disorder. These results are consistent with those described in the literature, it suggests that dyslexics can implement compensation strategies both at the behavioral and neuronal level. They call on those in charge of the Moroccan education system to recognize the existence of learning disabilities of neurobiological origin in order to address the necessary care for children who suffer from them
Mental health among students with neurodevelopment disorders: case of dyslexic children and adolescents
No full textABSTRACT Several research studies have been devoted to study the links between emotional disorders and learning disabilities. However, very minimal of this research has focused on dyslexic students. Objective: The objectives of this study were as follows: (1) to assess self-esteem, anxiety, and depression in dyslexic Arabic-speaking children and adolescents and (2) to describe psychiatric comorbidities in these subjects by comparing them to their non-dyslexic peers. Methods: In total, 205 students (56 dyslexics and 149 good readers), pursuing their education in ordinary schools in the Beni Mellal-Khenifra region of Morocco responded to Taylor’s Self-Assessment Scale of Anxiety, Beck’s Depression Questionnaire, and the Coopersmith Self-Esteem Inventory (SEI). Results: Overall, dyslexics were more anxious, more depressed, and had disturbed self-esteem compared to their non-dyslexic peers. The percentage of psychiatric comorbidity was higher in the dyslexic group. Conclusions: The results of this study highlight the need for a multidisciplinary approach that integrates emotional needs assessment into the rehabilitation care of dyslexic children and adolescents
Distribution of delta sleep-inducing peptide in the newborn and infant human hypothalamus: an immunohistochemical study
No full textThe distribution of delta sleep-inducing peptide immunoreactive cell bodies, fibers, and terminal-like structures was investigated in the normal human hypothalamus during the first postnatal year, using immunohistofluorescence and peroxidase anti-peroxidase techniques. Immunolabeled perikarya were relatively few and were mostly scattered through the anterior (preoptic) and mediobasal regions (infundibular nucleus) of the hypothalamus. DSIP-immunoreactive fibers and terminal-like fibers were observed throughout the entire rostro-caudal extent of the hypothalamus. They exhibit high densities in the preoptic region, the organum vasculosum of lamina terminalis, infundibular nucleus and median eminence. Moderate to low densities of DSIP-immunoreactive fibers were observed in the other hypothalamic structures, located in the anterior and mediobasal regions of hypothalamus, such as periventricular, paraventricular, suprachiasmatic, ventromedial, dorsomedial and parafornical nuclei. In the present study, the analysis of the immunohistochemical pattern of DSIP-immunoreactive neuronal elements in the human infant hypothalamus during the first postnatal year provided evidence of the presence of several differences. We have found qualitative age-related changes in the density of DSIP immunoreactivity in several hypothalamic structures such as the anterior region and the median eminenc
Distribution of delta sleep-inducing peptide in the newborn and infant human hypothalamus: an immunohistochemical study
No full textDevelopmental dynamics of neurotensin binding sites in the human hypothalamus during the first postnatal year
No full textThe aim of the present study was to determine a detailed mapping of neurotensin (NT) in the human hypothalamus during the first postnatal year using an in vitro quantitative autoradiography technique and the selective radioligand monoiodo-Tyr3-neurotensin (2000 Ci/mM). Ten human postmortem hypothalami (aged from 2 hours to 1 year of postnatal age) were used. The binding constants were of high affinity (nanomolar range) and similar between all cases investigated. Furthermore, competition experiments showed insensitivity of these receptors to levobacastine. Autoradiographic distribution showed that NT binding sites were widely distributed throughout the rostrocaudal extent of the hypothalamus. This distribution was not homogeneous and regional variations existed. The highest densities were present mainly in the anterior hypothalamic level, especially in the preoptic region . Important NT binding site densities were also present at the mediobasal level, particularly in the paraventricular, parafornical and dorsomedial nuclei. At the posterior level, low to very low densities were observed in all the mammillary complex subdivisions, as well as in the posterior area. Although this topographical distribution was almost identical in each age period analyzed, age-related variations existed; the densities were higher in preoptic area of neonates compared to older infants.The developmental profile was characterized by a progressive decrease in NT receptors from the neonate period to 1 year of postnatal age with a tendency to reach adult levels. On the other hand, the low levels of NT binding sites observed in posterior hypothalamus did not vary during the first postnatal year. In conclusion, the present study demonstrates the occurrence of important NT binding sites density in different many regions of the human neonate/infant hypothalamus that are involved in the control of neuroendocrine and/or neurovegetative functions
PRENATAL RESTRAINT STRESS AFFECTS MATERNAL BEHAVIOR, EARLY NEUROBEHAVIORAL RESPONSE AND OXIDATIVE STRESS IN MICE PUPS.
No full textPhysicochemical Quality of Cow Raw Milk Produced in the Fkih Ben Saleh Area
No full textThe main objective of the present study was to evaluate the physicochemical quality of raw cow milk produced in Fkih Ben Saleh,one of the major milk production areas in Beni Mellal-Khenifra region in Morocco located in the North-Centre of Morocco. Physicochemical quality of raw milk was determined by assessing the analysis of Fat Content “FC”, Protein Content “PC”, TotalSolids “TS”, Solids No-Fat “SNF”, Acidity “Ac”, Brix “Bx”, Density “Ds”, Temperature “T°” and Alcohol Test “AT”, usingrecognized standardized methods and infrared methods for better assessing of characteristics (fat, protein, total solids and no-fatsolids contents). The results obtained from this study showed an average ranging from 34.06 to 38.60 g/l, 30.01 to 31.61 g/l, 40.53to 42.52 g/l, 116.03 to 121.51 g/l, 88.88 to 90.85 g/l, 9.87 to 10% for FC, PC, LC, TS, SNF and Bx, respectively. On the other hand, an average ranging from 14.62 to 15.04 D°, 6.68 to 6.76, 1.0208 to 1.0494, 0.517 to 0.532 was showed for Ac, pH, Ds and FP, respectively. Furthermore, all milk samples tested for AT were, in most cases, normal at different concentrations of 79, 76, 74 and 68% while T° of all samples collected from bulk milk was under 06 °C. The present findings showed a good quality of the milk produced in this area in terms of chemical and physical criteria. Finally, the milk originated from Fkih Ben Saleh could be considered as an important riche and source of fabrication of dairy products with high quality
