147 research outputs found
Mapping QTL controlling agronomic traits in a doubled haploid population of winter oilseed rape (Brassica napus L.)
No full textAACR2 and catalogue production technology: The relevance of cataloguing principles to the online environment
No full textMore than thirty five years have passed since the Paris Conference and cataloguers have witnessed profound changes in many aspects of catalogue production technology and also in bibliographic control and access during this period of time. In comparison to the past, cataloguers are less involved in the design and production of catalogues and bibliographic databases particularly in terms of the interfaces, the types of indexes and the ways in which records and retrieval results are displayed. These changes and developments (see Appendix one) have presented cataloguers with some basic questions about the fundamental principles of record creation and catalogue construction.
Although present online catalogues are benefiting from more advanced hardware and software, there are still considerable, serious problems in searching, retrieval, and display of bibliographic information in present systems, which influence their functions and usefulness. This, as has been highlighted in the literature, may be because some of the present cataloguing principles and rules are inadequate, less relevant or irrelevant to the new electronic environment. A review of the literature of the last two decades indicates that, parallel to the increasing developments in online catalogues, the cataloguing community has been addressing the need for a re-thinking of cataloguing principles and rules in light of the new environment. It is often claimed that AACR2’s rules are based on concepts and principles from the pre-machine period and that they do not serve us well in giving guidance in the construction of electronic catalogues.
Given the influence of all the changes and developments in the world of catalogues and cataloguing, a fundamental re-examination of our cataloguing principles seems very necessary. In this paper some of the basic principles of AACR2 which have been highlighted in the literature as those most likely to be influenced by the new technology will be re-examined in the light of both the present and the potential characteristics and capabilities of the online environment. The aim is to examine the extent to which AACR2 matches or fails to match the capabilities of present systems and those of the near future, for searching, retrieval and display of bibliographic information. In other words, to address how catalogue form and production affects, or is in turn influenced by, the principles upon which AACR2 is based.
The approach used in this paper is to match individual capabilities of online catalogues with the basic principles of AACR2R. A major focus will be the basic concepts of the code’s principles, the logic of their application and the relationship of these principles to the logic of the online catalogue, as well as an examination of the types of principles and rules that are likely to change when moving from a manual catalogue to an online catalogue. In this regard, the needs and expectations of the different catalogue users are also taken into consideration
Speciation of Tc(IV) in chloride solutions by capillary electrophoresis
No full textBrowse Search My Profile Activate Help Home > List of Issues > Table of Contents > Abstract Speciation of Tc(IV) in chloride solutions by capillary electrophoresis Author(s): Xiaolan Liu | Frédéric Poineau | Massoud Fattahi | Bernd Grambow | L. Vichot doi: 10.1524/ract.93.5.305.64276 View PDF article (245 K) View table of contents Email this link Add to my alerts What is RSS? Trouble viewing articles as PDF? Radiochimica Acta Print ISSN: 0033-8230 Volume: 93 | Issue: 5/2005 Cover date: 20050501 Page(s): 305-309 Abstract text A method for speciation of Tc(IV) species (TcCl62− and TcCl5(H2O)−) in chloride solutions, using capillary electrophoresis (CE) technique was developed. The proposed method has overcome the difficulties of unstable oxidation states analysis by shortening their travel time in the capillary. TcCl62− and TcCl5(H2O)− were thus separated without being hydrolyzed and polymerized, and their UV/Vis spectra were recorded. With a 1 M HCl/NaCl buffer solution (pH=1), the electrophoretic mobilities were determined as 5.47×10−4 cm2/Vs for TcCl62− and 2.13×10−4 cm2/Vs for TcCl5(H2O)− at 25 °C. The total analysis time for one run is 12 minutes
Comparison of Freezing and Hydrate Formation Methods in Removing Chloride and Bromide Ions from Brine
No full textThe growing population and enhanced industrial activities coupled with limitations on freshwater availability have led to efforts to desalinate salt water from the seas. Membrane and thermal technologies are the two commonly used for this purpose. In this study, the direct freezing and hydrate formation techniques were used for salt water desalination. Materials and Methods: Distilled water, sodium chloride, and sodium bromide were used as raw materials in the experiments. The experimental setup included a stationary reactor with two coaxial cylinders, in which ice crystals were deposited outside the cool inner cylinder to increase the salt concentration in the residual brine. An electrical conductivity instrument was used to measure sal removal. Results: Salt removal was shown to decrease with increasing salt concentration in the direct freeze method. A different trend was, however, observed in the hydrate formation method; salt removal was negligible at low concentrations in this method but increased at high concentrations before a constant value was reached. Overall, the hydrate formation recorded a higher salt removal efficiency than the other method. To investigate the effect of anion size on salt removal efficiency, experiments were carried out using NaCl and NaBr, which have the same cation but different anion sizes. Result showed that removal efficiency increased with increasing anion size. Conclusion: It was found that increasing ion radius leads to the lower likelihood of ion presence in the crystal lattice, thereby reducing salt removal efficiency. On the other hand, low concentrations of salt serve as site for the generation of cores, which naturally serve as removal accelerators
Hepatocellular carcinoma incidence at national and provincial levels in Iran from 2000 to 2016: A meta-regression analysis
No full textBackground The incidence of Hepatocellular carcinoma (HCC), the most common primary liver cancer with high mortality, is undergoing global change due to evolving risk factor profiles. We aimed to describe the epidemiologic incidence of HCC in Iran by sex, age, and geographical distribution from 2000 to 2016. Methods We used the Iran Cancer Registry to extract cancer incidence data and applied several statistical procedures to overcome the dataset's incompleteness and misclassifications. Using Spatio-temporal and random intercept mixed effect models, we imputed missing values for cancer incidence by sex, age, province, and year. Besides, we addressed case duplicates and geographical misalignments in the data. Results Age-standardized incidence rate (ASIR) increased 1.17 times from 0.57 (95 UI: 0.37- 0.78) per 100,000 population in 2000 to 0.67 (0.50-0.85) in 2016. It had a 21.8 total percentage change increase during this time, with a 1.28 annual percentage change in both sexes. Male to female ASIR ratio was 1.51 in 2000 and 1.57 in 2016. Overall, after the age of 50 years, HCC incidence increased dramatically with age and increased from 1.19 (0.98- 1.40) in the 50-55 age group to 6.65 (5.45-7.78) in the >85 age group. The geographical distribution of this cancer was higher in the central, southern, and southwestern regions of Iran. Conclusion The HCC incidence rate increased from 2000 to 2016, with a more significant increase in subgroups such as men, individuals over 50 years of age, and the central, southern, and southwestern regions of the country. We recommend health planners and policymakers to adopt more preventive and screening strategies for high-risk populations and provinces in Iran. Copyright: © 2021 Fattahi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Enhanced hemocompatibility, antimicrobial and anti-inflammatory properties of biomolecules stabilized AgNPs with cytotoxic effects on cancer cells
No full textAbstract In the current research, we developed a safe method using Iranian yarrow extract for the synthesis of silver nanoparticles (IY-AgNPs) as reducing and stabilizing agents in different conditions. The prepared and stabilized IY-AgNPs under optimal conditions were characterized using FT-IR, XRD, TEM, and UV-vis techniques. Also, the blood-clotting, hemolytic, antioxidant, bactericidal and, fungicidal properties, cytotoxicity effects and inhibition of protein denaturation efficiency of IY-AgNPs were assessed in vitro. The stabilized IY-AgNPs with spherical shape and an average particle size of 19. 25 ± 7.9 nm did not show any hemolytic potential below 1000 µg/mL. These hemo-compatible NPs showed good blood-clotting ability by reducing clotting time (6 min relative to the control). These particles excellently inhibited the denaturation of bovine serum albumin (BSA) by 69.3–80.7% at concentrations ranging from 31.25 to 500 µg/mL compared to a reference drug. The outcomes showed that the IC50 values of IY-AgNPs were below 12.5 µg/mL against A375 cells and between 25 and 50 µg/mL against MCF-7 cancer cells. In addition, IY-AgNPs were bactericidal against Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus (especially), and were fungicidal against Candida albicans. Biosynthesized IY-AgNPs indicated a significant antioxidant activity (63.2%) at a concentration of 350 µg/mL. These attained results suggested that bio/hemo-compatible IY-AgNPs may be a promising candidate for applications in the medicinal fields (particularly for wound healing) as anti-bleeding, antimicrobial, antioxidant, anti-inflammatory, and anticancer agents
Validation of an in-house made rapid urease test kit against the commercial CLO-test in detecting Helicobacter pylori infection in the patients with gastric disorders
No full textBackground: H. pylori is a urease positive organism, and this activity in a gastric biopsy could be considered as a proof of the presence of H. pylori. For the reasons of high price and difficult accessibility to the commercial CLO-test in Iran, we designed an affordable equivalent test with high specificity, accuracy and availability. Methods: Biopsy samples from 80 symptomatic patients with gastrointestinal problems were included in this study. The results of our in-house made rapid urease kit were compared with the commercial CLO-test up to 3 hours and 24 hours after inoculation of the biopsy samples. Culture results and gram staining were proposed as gold standard. Results: Helicobacter pylori was isolated from 36 patients (45.0%) after cultivation of biopsy samples. After 3 hours, 33 (91.6%) cases of positive samples for H. pylori, showed urease positive reaction using both, in-house made and CLO-test kits. However, 2 (5.5%) cases showed urease reaction at 24 hours using both the kits. The specificity of 100% was determined for both, in-house made and commercial CLO-test kits after 3 hours. The sensitivity for both the kits was estimated at 97.1% after 3hours. However, after 24 hours, sensitivity and specificity of 97.1% and 88.64% was estimated for the in-house and 97.2 % and 95.4% for the commercial CLO-test kits, respectively. Conclusion: Specificity and sensitivity of 100% and 97.1 % for up to 3 hours follow biopsy sampling, could be considered as an advantage for our in-house rapid urease kit. Moreover, the rapid urease agar media designed in our lab is cost-effective with adequate sensitivity and specificity levels for the detection of H. pylori, compared with the commercial CLO-test
Knowledge of medical professionalism in medical students and physicians at Shahid Beheshti University of Medical Sciences and affiliated hospitals-Iran
No full textAlthough medical professionalism is a fundamental aspect of competence in medicine and a distinct facet of physicians' competence, evidence suggests that the subject of professionalism is not taught or assessed as part of medical students' curricula in Iran and many other countries. Assessing the knowledge of medical students and physicians about medical professionalism seems to be helpful in identifying the weaknesses of training in the field of professionalism and devise plans for future training on the subject. The present cross-sectional, quantitative, observational, and prevalence study recruited 149 medical interns, clinical residents, physicians, and professors working in hospitals selected through stratified random sampling using a questionnaire designed by the researchers and confirmed for its validity and reliability. The results were analyzed by Stata at a significance level of 0.05. Out of 149 cases, 61.64 were male with the mean age of 30.81 years. A total of 66 participants (44.29) (95 confidence interval CI: 36.44%-52.44%) had heard and 83 (55.70%) (95% CI: 47.55%-63.55%) had not heard the term 'medical professionalism' before the study. After adjusting for potential confounders, age and degree did not have statistically significant difference in assessed knowledge of medical professionalism, but sex had (mean difference: 5.88, P=0.045), and the mean of the female was significantly higher than that of the male participants. The mean percentage of correct answers was 47.67. The present study demonstrated that the medical professionals working in the national healthcare system have an unfavorable theoretical knowledge about medical professionalism in Iran; although this does not indicate that their practices are unethical, it should be noted that one of the prerequisites of possessing a high level of medical professionalism and for establishing a proper relationship between the medical community and the patients is to have a proper knowledge of this concept. Improving behaviors and performances in medical professions requires adequate training on the concepts of medical professionalism and consequently the assessment of the levels of professionalism achieved in medical professionals. © 2016 the Author(s). Published by Wolters Kluwer Health, Inc. All rights reserved
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