63 research outputs found
Cerebral Infarction as the First Presentation of Tuberculosis in an Infant: A Case Report
No full textHepatic and Renal Function Tests and Routine Hematological Markers in Patients with Cerebrovascular Accident and Transient Ischemic Attack
No full textBackground and Aim: Cerebrovascular accident (CVA), also known as stroke, is a vascular syndrome that is the second leading cause of death in the world after ischemic heart disease. Transient ischemic attacks (TIAs) is a warning sign for CVA so that 20% of patients with TIA experience a subsequent stroke within 90 days. Hence, identification of laboratory markers is crucial for the prognosis and diagnosis of patients with CVA and TIA. Changes in some laboratory markers occur in patients with CVA and TIA. Thus, the present study aimed to evaluate hepatic and renal function tests and routine hematological markers in patients with CVA and TIA.
Methods: The present study was a cross - sectional analytical study. The study population was patients with CVA and TIA who were hospitalized in Abadan and Khorramshahr educational hospitals from March 21, 2019, to March 19, 2020. One hundred patients with CVA and one hundred patients with TIA were randomly selected and the necessary information (age, sex, liver enzymes, renal function tests, FBS, and routing hematologic markers including CBC, ESR, PT and PTT) of the patients was collected from HIS (Hospital Information System) of Abadan and Khorramshahr educational hospitals. Liver, kidney and hematologic diagnostic markers were evaluated by age and gender. Data analysis was performed using a t -test (to compare gender difference of laboratory markers in CVA and TIA groups) and one-way ANOVA (to compare laboratory markers among age groups of patients with CVA and TIA). Simple linear regression was used to examine the relationships between changes in FBS (mg / dl) and changes in laboratory diagnostic factors.
Results: The results of this study showed that the highest frequency of patients with CVA (n= 130, 27.3%) and TIA (n= 49, 23.8%) was observed in the age group of 55-64 years. The results indicate that the mean level of some laboratory markers such as FBS (CVA: 174.32 ± 105.83; TIA: 150.32 ± 83.32), creatinine (CVA: 1.37 ± 1.32; 1.42 ± 1.09), LDH (CVA: 696.29 ± 344.90; TIA: 538.17 ± 230.76), and ESR (CVA: 52.41 ± 37.61; TIA: 14.00 ± 8.40) was higher than the normal range in both CVA and TIA. The mean of SGOT (34.10 ± 26.40 IU / L) and ALK (331.44 ± 370.78 IU / L) enzymes were higher than normal only in CVA patients and the mean of SGPT (33.08 ± 38.55 IU / L) was higher than normal only in TIA patients. It was also observed that in patients with CVA, with each unit increase in FBS, a significant increase occurs in K+ level (P < 0.001), WBC (P= 0.003), and RBC (P= 0.031) count, as well as a significant decrease in Na+ level (P= 0.008).
Conclusion: The results of the present study showed an increase in the level of FBS, ESR and LDH both in CVA and TIA. While SGOT and ALK increased only in CVA patients, SGPT showed an increase only in TIA patients.
*First Corresponding Author: Esmat Radmanesh; Email: [email protected]; ORCID ID: 0000-0003-1369-6580
Second Corresponding Author: Sahar Golabi; Email: [email protected]
Please cite this article as: Monfared A, Fadavipour M, Golabi S, Kamyari N, Zahedi A, Hazbenejad A, Kanani K, Jelvay S, Tajvidi M, Radmanesh E. Hepatic and Renal Function Tests and Routine Hematological Markers in Patients with Cerebrovascular Accident and Transient Ischemic Attack. Arch Med Lab Sci. 2023;9:1-9 (e3). https://doi.org/10.22037/amls.v9.3925
An operational sociohydrological model to understand the feedbacks between community sensitivity and environmental flows for an endorheic lake basin, lake Bakhtegan, Iran
No full textOver abstraction for agricultural production and droughts in the Bakhtegan basin in southwest Iran has led to decreased lake volumes and has even dried in some years. These problems have occurred in the basin as a result of neglecting the roles that humans have played in lake desiccation. This study developed a socio-hydrological model to understand such dynamic interactions between the economy and community's sensitivity to the environment in the period of 1999 to 2013. The WEAP model was used to simulate the hydrological system that is (bi-directionally) coupled to a society model simulating community sensitivity. A multi-objective optimization algorithm was used to estimate the parameters of the coupled model. The results of the model calibration and validation in estimating the simulated discharges show good performance of the model in simulating observed streamflows (R2 and NSE ranging between 0.73 and 0.99 and 0.31 to 0.99 respectively), agriculture water supplied (R2 and NSE ranging between 0.00 and 0.69 and −7.08 to 0.58 respectively), migration and population (R2 and NSE for migration: 0.29 and 0.63). The results of the integrated model on community response showed that attention to environmental conditions, such as lake levels, was heightened right after the drought events of 2000–2001 and 2008–2010. The effect of the latter event was even accentuated by several human interventions such as operationalization of Sivand and Mollasadra dams and transfer of pristine lands to agriculture. This led to major contraction of the lake. The model interprets that heightened community sensitivity as a result led to public policy dialogue and change. Water was taken away from agriculture and given to the environment leading to temporary lake revival. This was also confirmed by reviewing government decisions in 2011, further validating the value of socio-hydrological models in interpreting feedbacks between community sensitivity and environmental flows.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Water Resource
Congenital spinal tumor in a patient with encephalocele and hydrocephalus: a case report
No full textAbstract Introduction Encephalocele is a rare congenital abnormality of the central nervous system, where brain tissue protrudes from a defect in the skull. Some anomalies are associated with encephalocele. However, the association of spinal teratoma and encephalocele has not been reported in the English literature. Case presentation We report the case of an Iranian girl with a history of encephalocele surgery, who, at the age of four years, developed an intramedullary spinal teratoma, and discuss the pathogenesis of this association. Conclusion To the best of our knowledge, this is the first report of an association between encephalocele and spinal teratoma.</p
Nonaqueous Interfacial Polymerization-Derived Polyphosphazene Films for Sieving or Blocking Hydrogen Gas
No full textA series of cyclomatrix polyphosphazene films have been prepared by nonaqueous interfacial polymerization (IP) of small aromatic hydroxyl compounds in a potassium hydroxide dimethylsulfoxide solution and hexachlorocyclotriphosphazene in cyclohexane on top of ceramic supports. Via the amount of dissolved potassium hydroxide, the extent of deprotonation of the aromatic hydroxyl compounds can be changed, in turn affecting the molecular structure and permselective properties of the thin polymer networks ranging from hydrogen/oxygen barriers to membranes with persisting hydrogen permselectivities at high temperatures. Barrier films are obtained with a high potassium hydroxide concentration, revealing permeabilities as low as 9.4 × 10-17 cm3 cm cm-2 s-1 Pa-1 for hydrogen and 1.1 × 10-16 cm3 cm cm-2 s-1 Pa-1 for oxygen. For films obtained with a lower concentration of potassium hydroxide, single gas permeation experiments reveal a molecular sieving behavior, with a hydrogen permeance of around 10-8 mol m-2 s-1 Pa-1 and permselectivities of H2/N2 (52.8), H2/CH4 (100), and H2/CO2 (10.1) at 200 °C.ChemE/Advanced Soft MatterOLD ChemE/Organic Materials and Interface
Dual-source computed tomography angiography for diagnosis and assessment of coronary artery disease: Systematic review and meta-analysis
No full textLow temperature pyrolysis of thin film composite polyphosphazene membranes for hot gas separation
No full textHighly selective thin-film composite membranes for hot hydrogen sieving are prepared via the pyrolysis of thin cyclomatric polyphenoxy phosphazene films that are prepared via a non-conventional interfacial polymerization of hexachlorocyclotriphosphazene with 1,3,5-trihydroxybenzene or m-dihydroxybenzene. The presence of the cyclic phosphazene ring within the weakly branched polymer films gives rise to a distinct thermal degradation evolution, with an onset temperature of around 200 °C. For the trihydroxybenzene derived material, the hydrogen permselectivity of the films shows a maximum pyrolysis temperature of around 450 °C. At this temperature a compact atomic structure is obtained that comprises mostly disordered carbon and accommodates P–O–C and P–O–P bonds. During thermal treatment, these films reveal molecular sieving with permselectivities exceeding 100 for H2/N2, H2/CH4, and H2/CO2, and a hydrogen permeance of 2 × 10−10 to 1.5 × 10−8 mol/m2/s/Pa (0.6-44.8GPU), at 200 °C. At ambient temperatures, thin films are very effective barriers for small gas molecules. Because of the inexpensive facile synthesis and low- temperature pyrolysis, the polyphosphazene films have the potential for use in high-temperature industrial gas separations, as well as for use as barriers such as liners in high- pressure hydrogen storage vessels at ambient temperature.ChemE/Advanced Soft MatterOLD ChemE/Organic Materials and Interface
Accuracy of imputation to infer unobserved APOE epsilon alleles in genome-wide genotyping data
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