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Il demiurgo è ibrido, ovvero ermafrodita. Letture postasburgica e postcoloniale di «Die andere Seite» di Alfred Kubin: [The demiurge is a hybrid, that is a hermaphrodite. Post-Habsburg and post-colonial interpretations of «Die andere Seite» by Alfred Kubin]
Full text linkThe Other Side narrates the story of an anachronistic regime built up in Asia with remains of Decadent Europe. Before its collapse, due to the impossibility of existing against history and nature, the narrator concludes: «The demiurge is a hybrid». This paper studies the identity of the demiurge in order to clarify the meaning of this alienating statement. In doing so, it recognizes that the extraordinary regime reflects many features of the Habsburg myth; and also, that as an “experiment of Austria” it needs to take place elsewhere, where the western repressed dreams of power can be fulfilled: in a colony
Effetti del gel piastrinico sul rilascio di citochine coinvolte nei processi di cicatrizzazione e di rigenerazione tissutali
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Hypoxia modulates the release of cytokines by human peripheral blood mononuclear cells
No full textCytokines are regulatory proteins well known for their pleiotropic actions on a variety of cells. It is well known that local hypoxia is a very common condition and it may control the release of cytokines, physiologically relevant in controlling cell proliferation. For these reasons, we decided to study the production of cytokines by resting and phytohaemagglutinin (PHA)-activated peripheral blood mononuclear cells (PBMC), either at normal (20% O22 pO2 140 mmHg) or lower oxygen tension (2% Og pO2 14 mrnHg).Hypoxia significantly modulates the production of cytokines in human PBMC: Interleukin-2 (IL-2), Interleukin-4 (IL-4) and gamma-interferon (IFN) production increased 110, 70 and 50% of controls, respectively, in PHA-stimulated PBMC . Moreover, in hypoxia, IL-6 production was significantly enhanced in both resting and PHA-stimulated PBMC by 36 and 37%, respectively. On the other hand, in hypoxia IL-10 production decreased in both resting and stimulated PBMC, being 80 and 67% of controls, respectively. PBMC proliferation was not significantly affected by hypoxia, even though PBMC susceptibility to PHA was about 80% of controls (p<0.05), after 40 hr of treatment. By evaluating these data, it appears that hypoxia modifies the production of cytokines by PBMC. These results have both theoretical and practical interest because local hypoxia is very common in several conditions, as inflammation, local ischemia and is also a host nonspecific defense against infection. Further, they suggest a differential pattern of cytokine production "in vivo" in hypoxic tissues
Studies on the biological effects of ozone: 8. Effects on the total antioxidant status and on interleukin-8 production
No full textOzone (O3) is a controversial gas because, owing to its potent oxidant properties, it exerts damaging effects on the respiratory tract and yet it has been used for four decades as a therapy. While the disinfectant activity of O3 is understandable, it is less clear how other biological effects can be elicited in human blood with practically no toxicity. On the other hand plasma and cells are endowed with a powerful antioxidant system so that a fairly wide range of O3 concentrations between 40 and 80 microg/ml per gram of blood (approximately 0.83-1.66 mM) are effective but not deleterious. After blood ozonation total antioxidant status (TAS) and plasma protein thiol groups (PTG) decrease by 20% and 25%, respectively, while thiobarbituric acid reactive substances (TBARS) increases up to five-fold. The increase of haemolysis is negligible suggesting that the erythrocyte membrane is spared at the expense of other sacrificial substrates. While there is a clear relationship between the ozone dose and IL-8 levels, we have noticed that high TAS and PTG values inhibit the cytokine production. This is in line with the current idea that hydrogen peroxide, as a byproduct of O3 decomposition, acts as a messenger for the cytokine induction
Prevalenza dei marcatori del virus dell'epatite B in un gruppo di studenti e specializzandi in odontoiatria
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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