223 research outputs found
Some epigenetic aspects of spermatogenesis dysfunctions
No full textContemporary society faces a relatively high frequency of spermatogenesis dysfunctions. The factors that cause these dysfunctions can affect the structure of DNA,
as well as lead to various epigenetic changes. The main epigenetic mechanisms of
gene function regulation are DNA methylation, histone changes, and chromatin
remodeling. Currently, research on sperm epigenome has a a direction of perspective
Relatives comprehansion about hematooncological patient care
No full textDarba autore Vlada Sutjagina studē Latvijas Universitātē. Bakalaura darba tēma: „Tuvinieku izpratne par hematoonkoloģisko pacientu aprūpi”.
Darba mērķis: Noskaidrot tuvinieku izpratni par hematoonkoloģisko pacientu aprūpi.
Hipotēze: Hematoonkoloģisko pacientu tuvinieku izpratne par bērnu aprūpi ir pietiekoša.
Darba uzdevumi: Izpētīt zinātnisko literatūru un avotus par ķīmijterapiju un aprūpi hematoonkoloģiskiem pacientiem, pielietot H. Perlau aprūpes teoriju darba teorētiskajam pamatojumam, izstrādāt anketas jautājumus hematoonkoloģisko pacientu tuviniekiem, veikt aptauju, apkopot un analizēt iegūtos datus, izdarīt secinājumus un izvirzīt priekšlikumus, balstoties uz anketas iegūtiem datiem.
Darbā analizēta zinātniska literatūra un informācija par hematoonkoloģiskas saslimšanas būtību, ķīmijterapijas iespējamām blaknēm, higiēnas pasākumiem un uzturu ārstēšanas laikā, par pacientu aprūpi ar implantēto centrālo venozo katetru.
Pētījuma ietvaros veikta anketēšana vienā no Rīgas slimnīcām, lai noskaidrotu pacientu tuvinieku izpratni par bērnu aprūpi hematoonkoloģijā.
Darbs sastāv no teorētiskās un pētnieciskās daļas, kas ietver 18 diagrammas, 1. pielikumu, izmantoti 31 literatūras avoti.
Atslēgas vārdi: aprūpe, ķīmijterapija, bērns, tuvinieks.The author Vlada Sutjagina studying Latvian University. The theme: "Relatives comprehansion about hematooncological patient care”.
The goal : to find loved ones understanding of patient care hematoonkoloģisk.
Hypothesis: the patients ' relatives of Hematoonkoloģisk understanding of child care is adequate.
Terms of Reference: to explore the scientific literature and sources about the chemotherapy and nursing hematoonkoloģisk patients, using H. Peplau care theory, develop a questionnaire for hematoonkoloģisk patients ' relatives, take the survey, collect and analyze the data obtained, draw conclusions and make proposals on the basis of the questionnaire obtained data.
The paper analyzed the existing literature and information on possible side-effects of chemotherapy during treatment of neutropenia and neutropenic diet during the treatment of patients with intravenous catheter port.
How to study one of Riga's hospitals, to determine parents' awareness of the nature hematoonkoloģisko patient care during chemotherapy.
The work consists of a theoretical part and research parts, which includes 18 charts 1 run-on, 31 used literary source.
Keywords: care, chemotherapy, child, relative
Phytochemical study of a selected plant taxon. Procyanidins of Vaccinium macrocarpon in food supplements.
No full textCharles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Botany and Ecology Author: Vlada Kazaková Supervisor: Prof. RNDr. Luděk Jahodář, CSc. Title of master's thesis: Phytochemical study of a selected plant taxon. Procyanidins of Vaccinium macrocarpon in food supplements. Backround: The main objective of this work was to analyze food supplements containing Vaccinium macrocarpon, especially to evaluate the content of substances that are considered to be effective against urinary tract infections. Methods: Preparations were analyzed by TLC and HPLC techniques, tested for antioxidant activity by method utilizing DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging. Proanthocyanidins content was determined by using method based on the reaction with DMAC (4-dimethylaminocinnamaldehyde). Results: An overview of the issue of food supplements containing Vaccinium macrocarpon was created. Concentrations of proanthocyanidins in samples were determined. The content in recommended daily dose of preparations ranged from 4,2 mg to 54,3 mg. Conclusions: Proanthocyanidins from Vaccinium macrocarpon affect the ability of bacteria to adhere to epithelium of the urinary tract. Suitable method of their determination is method based on reaction with DMAC. Results revealed..
Promote successful adaptation of younger children in preschool
No full textVladas Ernstsones kvalifikācijas darbs „Jaunākā pirmsskolas vecuma bērnu sekmīgas adaptācijas veicināšana pirmsskolā” ir pētījums par bērnu sekmīgas adaptācijas veicināšanu pirmsskolā. Pētījuma mērķis ir teorētiski izzināt un praktiski izpētīt jaunākā pirmskolas vecuma bērnu sekmīgas adaptācijas veicināšanas iespējas pirmsskolas izglītības iestādē. Lai sasniegtu pētījuma mērķi, tika izvirzīti šādi uzdevumi: •analizēt teorētisko literatūru par adaptācijas procesu pirmsskolas iestādē; •analizēt bērnu adaptācijas procesa īpatnības pirmsskolas iestādē; •raksturot pirmsskolas un ģimenes iespējas adaptācijas veicināšanai; •veikt praktisku pētījumu “X” pirmsskolas izglītības iestādē par ģimenes un pirmsskolas sadarbību bērnu adaptācijas veicināšanai; •izdarīt secinājumus un sniegt ieteikumus. Šajā darbā autore piedāvā skatījumu uz to, kā pedagoga un vecāku sadarbība var veicināt sekmīgu adaptāciju pirmsskolas izglītības iestādē, kā arī mazināt bērnam stresu un baiļu sajūtu šajā dzīves posmā. Darbs sastāv no 47 lappusēm, 5 tabulām, 1 attēla, 2 diagrammām un 23 literatūras avotiem Atslēgvārdi: pirmsskolas izglītības iestāde, adaptācija, ģimene, bērni, sadarbība.Qualification work “Promote successful adaptation of younger children in preschool”, written by Vlada Ernstsone is a study about successful adaptation of children in preschool. The aim of qualification work is theoretically find out and practically explore, how better promote possibilities of younger children adaptation in preschool. To archieve this aim author had to do the followinig tasks: •Analyze literary materials about adaptation process in preschool; •Analyze specifics of children adaptation process in preschool; •Describe the possibilities of family and preschool cooperation to help promote successful adaptation; •Do a a practical research about possibilities of family and preschool cooperation to help promote successful adaptation in preschool “X”; •Develop conclusions and suggestions; In this Qualification work author offers a view of that, how the coorperation between pedagogue and parents can improve the adaptation in preschool, as well as decrease the stress and fears for children in this stage of life. Work consists of 47 pages, 5 tables, 1 image, 2 diagrams and 23 bibliographical sources. Key words: preschool, adaptation, family, children, cooperation
Problema sănătății și sanocreatologia
No full textÎn articol sunt prezentate date privind amenințările existenței societății contemporane cauzate de starea alarmantă a sănătății populației: rata înaltă a morbidității și mortalității populației; întinerirea bolilor cronice; vectorul ascendent al morbidității bolilor noninvazive (cardiovasculare, oncologice, endocrine, mintale etc.); degradarea biologică precoce a speciei Homo sapiens; etc. Sunt aduse dovezi referitor la unica cale de soluționare a problemei sănătății prin crearea, menținerea și fortifi carea dirijată a sănătății – obiective primordiale ale direcției noi în biomedicină – sanocreatologia, precum și prezentate succint bazele științifi ce ale acesteia
Features of reproductive function in viral hepatitis and diabetes mellitus: review
No full textViral hepatitis, accompanied by diabetes, is one of the most common
pathologies that can have a negative impact on reproductive function. The
purpose of the article is to identify the features of changes in the functioning of the reproductive system in this combined pathology. The relationship between psycho-emotional changes that arise as a result of the
above-mentioned diseases and reproductive function is also considered
Gynecomasty: ethiopathogenesis, diagnostics, indications for surgery, types of surgery, results, complications – literature review.
No full textTitle. Gynecomasty: Ethiopathogenesis, Diagnostics, Indications for Surgery, Types of Surgery, Results, Complications – Literature Review Author. Vlada Bernotaitė (VI year) Supervisor. Dr. Indrė Sakalauskaitė, Clinic of Rheumatology, Orthopaedics Traumatology and Reconstructive Surgery Aim of the study. To conduct a literature review on the etiopathogenesis of gynecomastia, diagnosis, treatment, indications for surgical treatment, surgical treatment methods, results and complications. Methods and materials. A review of the scientific literature using evidence – based medicine sources (PubMed, Google Scholar, Elsevier) was conducted in 2023 – 2024. Key words used in the search: "Gynecomastia", "Gynecomasty", "Surgery", "Breast", "Mastectomy", "Liposuction", "Pseudogynecomastia". During the search of the scientific literature, 350 full-text articles published in English were reviewed, of which 71 were analyzed. Results. The prevalence of gynecomastia is increasing due to changes in the modern lifestyle and although it is a benign condition, it strongly disturbs psychological well-being and leads to a worsened quality of life. Since the development of gynecomastia is a long-term process, it is often diagnosed when proliferative changes have already occurred in the breast tissue. Although in the literature pharmacological treatment options are available, there is no consensus on the choice of drugs used and the optimal duration of pharmacological treatment. The gold standard of treatment is surgical treatment, which is more effective than pharmacological and provides better aesthetic results and a lower recurrence rate. Conclusions. Due to the wide variety of gynecomastia classifications and surgical methods in the scientific literature, choosing a specific surgical technique in an individual case can be difficult. None of the gynecomastia classifications proposed so far are universally accepted for use. In order to facilitate the work of the plastic surgeon in clinical practice and to achieve the most optimal treatment results, it is necessary to introduce a universally applicable classification of gynecomastia, which takes into account not only breast size and ptosis, but also the dominant type of tissue in the breasts, the quality of the skin and the presence of excess skin, body habitus, and other factors
The role of oncoprotective medicinal plants in modifying the intestinal microbiota
No full textAt the global level, humanity’s interest in natural remedies of plant origin against many diseases of various etiologies is currently increasing.
A whole series of medicinal plants possess anticancer capabilities, but it
is necessary to elucidate those plants, which simultaneously demonstrate
prebiotic activity, a fact that will be the basis for the further development
of phytooncoprotective microbial preparations
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