1,720,985 research outputs found
Early fetal akinesia sequence: A case report with unusual autoptic features
No full textIn this paper we report a case of early onset fetal akinesia, with unusual
pathological findings. This is a product of medical abortion of young, healthy,
unrelated parents. The mother's obstetrical history revealed two previous early
miscarriages and a suspicion of FADS in the second previous gestation. At 17
weeks of gestation, an ultrasound examination disclosed absence of fetal
movements, fixed extended knees and deformation of the feet. Amniocentesis showed
a normal 46, XX karyotype. Hydrops fetalis and multiple skin webs (pterygia),
which are usually present in cases of early fetal akinesia, were absent. A
diagnosis of arthrogryposis was made and the pregnancy was terminated at 17 weeks
of gestation. Postmortem examination was performed according to the necropsy
technique suggested by Langley. Thus, body weight and external measurement,
including crown-rump, crown-heel, foot lengths, head, thorax and abdominal
circumferences were estimated and compared with standard values for assessment of
fetal growth. External dysmorphic features were evaluated prior to the
evisceration. On internal examination the location and shape of every organ was
evaluated. Every organ, skin, muscles from different parts of the body, the brain
and spinal cord were sampled and histologically examined. External examination
revealed a female fetus with marked muscular hypoplasia of upper and lower
extremities with thin arms and legs and multiple joint contractures of lower
extremities. The face showed a flattened nose, micrognatia, hypertelorism, cleft
palate and low-set ears. There was also a small nuchal fold. The abdomen was
distended with a very thin and almost transparent wall. Histologically, muscles
were characterized by severe fibrosis with fatty infiltration and by moderate
variability in diameter of muscle fibers. The spinal cord disclosed a paucity of
anterior horn motor neurons. We suggest multiple pterygium as a diagnosis. Lethal
multiple pterygium syndrome (LMPS) is only a symptom and the precise diagnosis is
more likely to be spinal atrophy. We, moreover believe that the paucity of spinal
motoneurons could be due to the anomalies of programmed death during fetal
development and the consequence of genetic defects
High grade prostatic intraepithelial neoplasia with squamous differentiation
No full textAn unusual variant of prostatic intraepithelial neoplasia with prominent and extensive squamous differentiation is described. The lesion was identified in the transition zone of a 79 year old man with a three year history of increasing urinary obstructive symptoms and a clinical diagnosis of benign prostatic hyperplasia who underwent simple prostatectomy. Two years after surgery, prostatic biopsies showed atrophy and mild chronic inflammation, with no evidence of malignancy. This unusual intraepithelial lesion seems not to have been described before and may represent a new variant of high grade prostatic intraepithelial neoplasia (HGPIN) with squamous differentiation
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Bladder carcinosarcoma: a case observation
No full textCarcinosarcoma of the bladder is a very unusual neoplasm that arises more frequently in males with a greater incidence in the seventh decade of life. There are no patognomonic clinical findings or symptoms to address its presence. Symptoms, as for other bladder cancers, are fundamentally represented by haematuria and dysuria. It has a very aggressive clinical behaviour and it is histologically characterized by a malignant epithelial component associated with a sarcoma-like (sarcomatoid) component variably represented
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