1,721,286 research outputs found
Responsiveness and minimal important change of the Quebec Back Pain Disability Scale in Italian patients with chronic low back pain undergoing multidisciplinary rehabilitation
Full text linkBackground: There is still a lack of information concerning MIC of the QBPDS, that limits its use for clinical and research purposes. Aim: Evaluating responsiveness and minimal important change (MIC) of the Quebec Back Pain Disability Scale (QBPDS) in Italians with chronic low back pain (LBP). Design: Methodological research based on an observational study. Setting: Outpatient rehabilitation hospital. Population: Two hundred and one patients with chronic LBP. Methods: At the beginning and end of a multidisciplinary rehabilitation programme, patients completed the QBPDS. At the end of treatment, they completed a 7-level global perceived effect (GPE) scale, which was split to obtain a dichotomous outcome (improved vs. stable). Responsiveness was calculated by distribution-based [effect size (ES); standardised response mean (SRM); minimum detectable change (MDC95)] and anchor-based methods [Receiver Operating Characteristics (ROC) curves]. ROC curves were also used to compute the MIC (based on QBPDS change score, both absolute and expressed as percentage). Correlations between the change score of the QBPDS and GPE were calculated. Results: The ES was 0.29, the SRM was 0.43, and the MDC95 was 12 points. ROC analysis of the absolute change scores showed a MIC value of 6 points, with an area under the curve (AUC), sensitivity, and specificity of 0.83 (95%C.I. 0.77-0.90), 77.7% and 80.8%, respectively. ROC analysis based on the percent change score from baseline revealed a MIC of 18% with an AUC, sensitivity and specificity of 0.85 (95%C.I. 0.79-0.91), 80.6% and 80.8%, respectively. Correlation between change score of the QBPDS and GPE was ρ=-0.67. Conclusions: The QBPDS score change (expressed in both absolute value and percentage from baseline) was sensitive in detecting clinical changes in Italian subjects with chronic LBP undergoing multidisciplinary rehabilitation. In clinical practice, we recommend -where absolute change is lower than MDC- to rely on the MIC taking into account the percentage change from baseline condition. Clinical rehabilitation impact: The present study investigated the responsiveness and MIC of the QBPDS in a group of patients with chronic LBP. Our findings showed that the QBPDS score may classify with good to excellent discriminatory accuracy subjects who consider themselves as improved. Where examining change, we recommend to consider both MICs we provided (expressing score change both in absolute value and as a percentage from baseline), and disregard values lower than MDC95, not being discernible from measurement error
Responsiveness and minimal important changes of the tampa scale of kinesiophobia in subjects after lumbar fusion undergoing multidisciplinary cognitive behavioural rehabilitation
No full textThe Tampa Scale of Kinesiophobia (TSK) is a commonly-used measure for the assessment of fear of movement beliefs in chronic complaints, but its responsiveness in subjects after lumbar fusion has been never reported
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Preliminary study on the effects of high magnitude, low frequency of whole body vibration in physical actively osteoporotic women
No full textAim. Osteoporosis is nowadays affecting a large population. Recent studies, performed on animals and human beings, have shown that high magnitude, low frequency mechanical stimuli produce anabolic effects on bone tissue, increasing both bone density and strength. Aim of this study is to verify the effects of whole body vibration on bone tissue of trained osteoporotic women underwent to high magnitude and low-frequency vibration exercise on a vibrating platform.
Methods. Twenty-six osteoporotic women, trained with low impact exercise regimen, voluntarily participated in the study and were randomly divided in two groups: experimental (E) and control (C). All subjects weren’t submitted to any pharmacological therapy. The T-score, Ultrasound Bone Profile Index (UPBI) was calculated using the Amplitude-Dependent Speed of Sound (AD-SoS) measured with QUS.
Results. Thirteen osteoporotic women following four months of ten-minute treatments, three per week, of high magnitude (3.0 g) and low frequency (30Hz) mechanical vibration improved the Amplitude-Dependent Speed of Sound (AD-SoS) QUS parameter from 1878.67±79.45 to 1971. 17±78.69 m/s (P<0.002). The T-score in the experimental group shows an inversion trend passing from -3.50±1.13 to -2.18±1.12 (P<0.002) and the Ultrasound Bone Profile Index (UPBI) improves from 0.34±0.11 to 0.47±0.21 (P<0.01). In the control group (low impact exercise) any of these parameters considered shows significantly changes over the same period of time.
Conclusion. Given that these accelerations were well tolerated by the experimental cohort, that vibrations similar to these stimulated an increase in bone density and strength in humans, and that skeletal loading is an inevitable product of functional load bearing, we believe that vibration energy can represent not only a preventive approach but also a therapy for osteoporosis. For that, larger population scale studies must be performed in order to verify the effectiveness of vibration treatments and its combination with exercise regimen on the spine and the lower limbs to prevent bone loss falls and related bone fractures in elderly people
Preliminary study on the effects of high magnitude, low frequency of whole body vibration in physical activity of osteoporotic women
No full textAim. Osteoporosis is nowadays affecting a large population. Recent studies, performed on animals and human beings, have shown that high magnitude, low frequency mechanical stimuli produce anabolic effects on bone tissue, increasing both bone density and strength. Aim of this study is to verify the effects of whole body vibration on bone tissue of trained osteoporotic women underwent to high magnitude and low-frequency vibration exercise on a vibrating platform. Methods. Twenty-six osteoporotic women, trained with low impact exercise regimen, voluntarily participated in the study and were randomly divided in two group: experimental (E) and control (C). All subjects weren't to any pharmacological therapy. The T-score, Ultrasound Bone Profile Index (UPBI) was calculated using them Amplitude-Dependent Speed of Sound (AD-SoS) measured with QUS. Results. Thirteen osteoporotic women following four months of ten-minute treatments, three per week, of high magnitude (3.0 g) and low frequency (30Hz) mechanical vibration improved the Amplitude-Dependent Speed of Sound (AD-SoS) QUS parameter from 1878.67+/-79.45 to 1971.17+/-78.69 m/s (P<0.002). The T-score in the experimental group shows an inversion trend passing from -3.50+/-1.13 to -2.18+/-1.12 (P<0.002) and the Ultrasound Bone Profile Index (UPBI) improves from 0.34+/-0.11 to 0.47+/-0.21 (P<0.01). In the control group (low impact exercise) any of these parameters considered shows significantly changes over the same period of time. Conclusion. Given that these accelerations were well tolerated by the experimental cohort, That vibrations similar to these stimulated an increase in bone density and strength in humans, and that skeletal loading is an inevitable product of functional load bearing, we believe that vibration energy can represent not only a preventive approach but also a therapy for osteoporosis. For that, larger population scale studies must be performed in order to verify the effectiveness of vibration treatments and its combination with exercise regimen on the spine and the lower limbs to prevent bone loss falls and related bone fractures in elderly people
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