1,720,977 research outputs found
Valutazione del saggio Greenscreen HIV Ag-Ab per la diagnosi di laboratorio di infezione da HIV.
No full textCONFRONTO FRA DUE SAGGI IMMUNOENZIMATICI COMMERCIALI PER LA RICERCA DI ANTICORPI ANTI-HAV.
No full text
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
MALDI-TOF MS as new tool for the identification of serological biomarkers for diagnosis of hepatitis B and C viruses infections
No full textBackground: Hepatitis B virus (HBV) and Hepatitis C virus (HCV) represents two of the major health problem worldwide. Only few studies investigate by MALDI-TOF MS the presence of specific peptides/proteins that can be considered predictive indicators for HBV infection. In this study, we used MALDI-TOF MS to examine serum samples aiming at searching peptides/proteins that can be used as serological biomarkers to detect HBV and HCV.
Materials/methods: Fifty-six serum samples, received for diagnostic purposes with suspected HBV and/or HCV infection, previously analyzed with the diagnostic assays currently used in our laboratory and resulted positive or negative for HBsAg or HCVcoreAg, were examined by MALDI-TOF MS.
Results: In the first step, 3 different protein extraction approaches were evaluated to obtain valid, reliable and reproducible results. The protocol adopted involved ultracentrifugation of serum samples with water. The analysis performed at low molecular weight showed the presence of unique peaks for each class of sera (HBV-positive, HCV-positive or both negative), while the analysis carried out at high molecular weight showed the absence of significantly discriminating peaks. In particular, the detection of HBV-positive sera is associated with 8 discriminating peaks; similarly, detection of HCV-positive sera is associated with 8 discriminating peaks. Noteworthy the trend of the intensity of 3 peaks (3224, 6632, 7478 Da) showed a significantincrease or decrease depending on the virus responsible for the infection. However, it was not possible to identify the protein/
peptide matching to the markers found. The second step involved the creation of statistical models able to differentiate the three different categories of serum analyzed on the basis of these peaks. In particular, using this model it was correctly classified all 56 sera.
Conclusions: Our results demonstrated, on a limited number of sera with high concentration of specific antigen, the presence of peaks differentiating classes of positive sera, for both HCV, for the first time to our knowledge, and HBV, as already reported by other Authors. This could be a starting point to add MALDI-TOF MS as a tool for the diagnosis of such infections, being independent of antigen mutations that could affect the conventional assays
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