1,720,975 research outputs found
Build-up and switching of ferroelectric polarization in polyvinylindene fluoride
No full textFedosov S. N. Build-up and switching of ferroelectric polarization in polyvinylindene fluoride / S. N. Fedosov, A. E. Sergeeva // Зб. тез доп. 80-ї наук. конф. викл. акад., Одеса, 7–8 трав. 2020 р. / Одес. нац. акад. харч. технологій ; під заг. ред. Б. В. Єгорова. – Одеса : ОНАХТ, 2020. – P. 202–203. – Ref.: 2 tit
Polarization profiles in corona poled P(VDF-TFE) copolymer
No full textFedosov S. N. Polarization profiles in corona poled P(VDF-TFE) copolymer / S. N. Fedosov, O. Ye. Sergeeva // Priority directions of science and technology development : proc. of XI Intern. Sci. and Practical Conf., Kyiv (Ukraine), 11–13 July 2021. – Kyiv, 2021. – Р. 276–280 : fig. – Ref.: 3 tit
Vitamin B12 Transport Proteins: Crystallographic Analysis of beta-axial Ligand Substitutions in Cobalamin Bound to Transcobalamin
No full textSwitching of polarization in PVDF films: importance of screening by trapped charges
No full textFedosov S. N. Switching of polarization in PVDF films: importance of screening by trapped charges / S. N. Fedosov, A. E. Sergeeva, H. von Seggern // Збірник тез доповідей 81-ї наукової конференції викладачів академії, Одеса, 27–30 квіт. 2021 р. / Одес. нац. акад. харч. технологій ; під заг. ред. Б. В. Єгорова. – Одеса : ОНАХТ, 2021. – P. 165–168. – Ref.: 5 tit
How electric conductivity affects polarization in ferroelectric polymers
No full textFedosov S. N. How electric conductivity affects polarization in ferroelectric polymers / S. N. Fedosov, A. E. Sergeeva, H. von Seggern // Зб. тез доп. 80-ї наук. конф. викл. акад., Одеса, 7–8 трав. 2020 р. / Одес. нац. акад. харч. технологій ; під заг. ред. Б. В. Єгорова. – Одеса : ОНАХТ, 2020. – P. 200–201
Crystallization and preliminary X-ray diffraction analysis of human transcobalamin, a vitamin B-12-transporting protein
No full textRational design, synthesis and characterization of vitamin B12 bioconjugates as diagnostic and therapeutic drugs
No full textThe tumour cells take up proportionally more vitamin B12 than
non-proliferating cells due to an increased number of surface
receptors required for the endocytosis of the vitamin. Therefore,
vitamin B12 derivatives have the potential application as diagnostic or therapeutic antitumour agents. The rational design of bioconjugates based on cyanocobalamin (vitamin B12) has been performed by exploiting the structural knowlegde about the complex of cobalamin with its human transport proteins that became recently available. The structures point to the 5’-hydroxyl
group of the ribose moiety as the most promising site for the covalent attachment of active ligands to cobalamin to preserve the
affinity of the resulting analogue for the transport proteins. The
esterification of the ribosyl 5'-OH group of vitamin B12 with diethylenetriaminepentaacetic acid (DTPA) produces a chimeric molecule (B12-DTPA) able to chelate different metals. The gadolinium complex of this bioconjugate (B12-DTPA-Gd) has been characterized both in solution and in solid state
Release of toxic Gd3+ ions to tumour cells by vitamin B12 bioconjugates
No full textTwo probes consisting of vitamin B12 (CNCbl) conjugated to Gd chelates by esterification of the ribose 5’-OH moiety, Gd–DTPA–CNCbl (1; DTPA=diethylenetriamine- N,N,N’,N’’,N’’-pentaacetic acid) and Gd–TTHA–CNCbl (2; TTHA=tri- ACHTUNGTRENUNGethylenetetramine-N,N,N’,N’’,N’’’,N’’’- hexaacetic acid), have been synthesised and characterised
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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