13 research outputs found
3D Diagnosis in Dentistry
INTRODUCTION
3D imaging is rapidly changing diagnostic procedures in
all fields of dentistry. Intraoral scanners and three-dimensional
radiographs, Tc and ConeBeam, have entered the routine of
everyday clinical practice. Patient photography has also
evolved into stereophotogrammetry, which obtains threedimensional images of the face. The advancements in 3D
technologies have stimulated the production of software that
allows the anatomy of the dental patient to be reconstructed in
three dimensions. Technological development has stimulated
research in finding ways to improve diagnostic programming
and therapeutic programming. In recent years, many articles
have been published that compare 2D technologies to 3D
technologies in dental diagnosis. At the same time, new 3D
image analysis systems were studied, enhanced by the
development of artificial intelligence systems based on
machine learning. Research in the field of dentomaxillofacial
radiology concerns automated diagnosis of dental and
maxillofacial diseases, localization of anatomical landmarks
for orthodontic and orthognathic treatment planning, and
general improvement of image quality. Other recent research
evaluates the quality and use of intraoral scanners and 3D
software and printers for the design and implementation of
therapeutic means. CAD / CAM technology is used in many
fields of dentistry, especially in implantology, prosthetics,
orthodontics, and maxillofacial surgery. Surgical guides for
implantology and orthodontic miniscrews placement,
provisional and definitive prosthetic restorations, and many
orthodontic appliances are designed and built. In this field,
research and technology are revolutionizing clinical
procedures, which in many cases can follow a digital
workflow.
Finally, many studies propose the evaluation of
stereophotogrammetry as a means of integrating 3D diagnosis.
In this field, scientific research has produced works on the
evaluation of the means of image acquisition and on the
positioning of landmarks that allow measuring the proportions
*
Address correspondence to this author at the Dental Institute, Catholic
University of the Sacred Heart, Fondazione Policlinico Gemelli IRCCS. L.go A.
Gemelli, 8 – 00168 Rome, Italy; E-mail: [email protected]
of the facial volumes and accurately observing the effects of
therapies on soft tissues.
As a demonstration of the novelty and scientific interest in
this topic, the production of scientific works is constantly
increasing. The researchers are trying to overcome the gap in
the difficulty of using the technology through the proposal of
automatic 3D image processing systems, which make clinical
application easier.
This Guest Editor issue is particularly dedicated to
updating the knowledge regarding the use of digital devices in
the diagnostic process. One of the results in publishing articles
on 3D diagnosis is to show the community of dentists how to
use the new technologies in daily practice. I am grateful to the
Editorial Board of The Open Dentistry Journal at Bentham
OPEN for this special issue.
The articles collected in this issue report the novelties
brought by digital technologies in orthodontics. One of the
most peculiar effects of using new technologies is that dentists
are allowed to study the face of the patient and measure it
precisely. This aspect is very important for orthodontic
diagnosis, but its importance is growing in all the fields of
dentistry due to the increase of attention on the facial aspect.
Facial esthetic today has the same importance as dental
occlusion and function, thus has contributed to increasing the
multidisciplinarity of dental interventio
Quality of the information provided by ChatGPT for patients in breast plastic surgery: are we already in the future?
Introduction
In the recent years Artificial Intelligence has grown in popularity also in the field of Plastic Surgery;
For patients is becoming more and more common to use internet to gather plastic surgery
information and chatbot based on AI, such as ChatGPT, could be used for answering patient’s
questions.
The aim of this study was to assess the quality of medical information provided by ChatGPT
regarding three of the most common procedure performed in breast surgery: Breast Reconstruction,
Breast reduction and Augmentation mammaplasty.
Methods
The quality of information was evaluated through the Expanded EQIP scale. Responses where
collected from a pool made by ten resident doctors in Plastic Surgery and then processed by SPSS
software vers. 28.0.
Results
The analysis of the contents provided from ChatGPT showed a sufficient quality of the information
in all the topic selected, with an high bias in terms of distribution of the score between the different
items. There was a critical lack in the “Information data field” (0/6 score in all the 3 investigations)
but a very high overall evaluation concerning the “Structure data” (>7/11 in all the 3 investigations).
Conclusion
At the present time, AI could be an useful tool for patients, but some critical issues that need to be
faced from engineers and developers are still present. It’s definitely possible that in the future
models like ChatGPT will play an important role in improving patient’s consciousness about
medical procedures and surgical interventions, but their role must be considered ancillary to the one
of the surgeon
Primary Failure of Eruption: Clinical and Genetic Findings in the Mixed Dentition
CONTROL ID: 2639647
TITLE: Primary Failure of Eruption: Clinical and Genetic Findings in the Mixed Dentition
AUTHORS (FIRST NAME INITIAL LAST NAME): C. Grippaudo1, I. D'Apolito1, C. Cafiero1, B. Ricci1, S. A. Frazier-
Bowers2
AUTHORS/INSTITUTIONS: C. Grippaudo, I. D'Apolito, C. Cafiero, B. Ricci, Dental Institute, Università Cattolica,
Rome, ITALY|S.A. Frazier-Bowers, Department of Orthodontics, University of North Carolina, Chapel Hill, North
Carolina, UNITED STATES|
PREFERRED PRESENTATION TYPE: Oral
CURRENT SCIENTIFIC GROUPS & NETWORKS: Craniofacial Biology
ABSTRACT BODY:
Objectives: Eruption disorders represent an enigmatic aspect of dental and orthodontic diagnosis. Since the discovery
that Primary Failure of Eruption (PFE, MIM #125350) is due to a genetic defect, several mutations of the PTH1R gene
have been identified as causative. This study aimed to refine our understanding of the phenotype:genotype correlation
of PFE and PTH1R mutations in the mixed dentition. This characterization may lead to improved diagnostic
approaches and provide the foundation for downstream mechanistic studies to understand the pathogenesis of
PTH1R mutations.
Methods: DNA was extracted from saliva samples of 29 patients (3 families and 23 unrelated individuals) who
presented with clinical evidence of infraoccluded teeth. Mutational analysis was completed for the coding regions of
PTH1R gene following PCR amplification and direct sequencing.
Results: Eight of 29 cases revealed a heterozygous pathogenic variant in the PTH1R gene; 5 of 8 variants represent
distinct mutations within the cohort. One mutation (c.1765 T>C p.Trp89Arg) was found to segregate within a family
(n=3) represented by two generations. Mutational analysis using the dbSNP, HGMD and the ESP databases identified
the mutations were previously unreported. In silico analyses of all variants further predicted a putative pathogenic
effect. Extended clinical analysis of the cohrot verified that all the novel mutations co-segregated with the PFE
phenotype that included affection of the mixed dentition. Six of the 8 patients carrying a functional PTH1R mutation
were children in mixed dentition with one or more primary teeth affected.
Conclusions: We report that PFE in the mixed and permanent dentition positively correlates with pathogenic mutations
in the PTH1R gene. Further studies to identify additional genes and correlate the pathogenesis of PFE from mixed to
permanent dentition are ongoing and forthcoming.
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KEYWORDS: Primary failure of eruption (PFE), orthodontics, Dental eruption, genetics, mixed dention.
Support Funding Agency/Grant Number - Abstracts:
Financial Interest Disclosure: NONE
AWARDS:
Group Author Abstracts - Abstract:
Session Chair Volunteers - Abstracts: Not Interested
Special Scheduling Needs - Abstracts:
Student Status - Abstracts: No
Student Other Designation - Abstracts:
Abstract Submission - Track Selection: Clinician Trac
Exploring the Role of Caregivers in Day Surgery for Patients Undergoing Plastic and Reconstructive Surgery: A Comprehensive Patient and Caregiver Survey Approach
ABSTRACT:
This study investigates the interplay between Plastic and Reconstructive Surgery patients and their
respective caregivers in the Day Surgery Unit of Policlinico Umberto I, Rome, Italy. Utilizing a dual
survey approach, we explored the role in patient’s safety and the challenges faced by caregivers
during the perioperative period. The study, conducted at Policlinico Umberto I, covers all surgical
procedures from October to December 2023, encompassing skin cancer removal, fat grafting, scar
revisions, hand surgeries, and blepharoplasties. Patient demographics reflect varying age
distributions: 18-39 (4.9%), 40-59 (31.7%), 60-75 (34.1%), and over 76 (29.3%)
The role of pre-expanded free flaps in revision of burn scarring
The authors present two patients affected by scars resulting from burning of over 60 per cent of the total body area, in which the pre-expansion of a free flap has been used to increase the tissue surface useful for transfer from om the only area of residual healthy skin (left forearm, left parascapular region). In both cases it was possible to transfer abundant healthy tissue into the desired areas, obtaining a rapid release of the region, which made possible an early physical rehabilitation of the patient starting after the second postoperative week. One of the main problems encountered when facing surgical rehabilitation for the seriously burned patient, is the poor availability of skin donor areas suitable for reconstructive flaps. The pre-expansion of free flaps provides Int advantage in that it allows the few integral residual areas to be used, improving vascularization and therefore increasing the available surface. Furthermore, as pre-expansion reduces tension on the margins, it allows for the easier closing of the donor area, with a minor risk of complications and a better scar outcome. (C) 1997 Elsevier Science Ltd for ISBI. All rights reserved
Orbital metastases in a female patient with breast cancer
Breast cancer is the most common malignant disease among women, with a lifetime risk of approximately 10%. Frequent and well-known locations of metastases are bone, liver, lung, skin and brain, but tumour repetition has been seen in almost any anatomic site. Orbital involvement is quite rare, or perhaps underestimated. Orbit metastases (OMs) represent 1-13% of all orbital cancers, and are difficult to discriminate with other differential diagnoses, such as a simple blepharitis, or orbital pseudotumor, up to more complex forms of cancer such as lymphoma. The prevalence of OMs is calculated to occur in 2-4.7% of primitive cancer patients. Typical manifestations of orbital metastases include overall regional inflammation, mass effect causing displacement or ocular globe proptosis, pain, bone infiltration, Chemosis and eyelid swelling. Infiltration of soft tissue leads to ptosis, diplopia or enophthalmos. We report the case of a 70-year-old female patient who developed chronic inflammatory process of both orbital regions due to orbital metastases, without evidence of other systemic disease after 8 years from primary breast cancer diagnosis. The diagnostic pathway as well as the differential diagnosis are discussed. Copyright © by BIOLIFE, s.a.s
UAL Report on 14 years of clinical experiences
In the recent time the interest about UAL is greatly increased partly because with this technique it seems possible to guarantee constant and sure results, and partly because the machine manufactures have worked to make this procedure well known in a complete and full way.
With the major diffusion of the UAL the casisistic have increased too, the indications have widened, the complications began to show up, and the limit of the procedure have begun to be defined.
In these years the instrumentation constantly evolved, from the initial devices designed for plastic surgery manufactured by SMEI, until the more recent models on the actual market.
Purpose of this study is to compare the considerations made when the senior author firstly experienced UAL 14 years ago, with the actual orientations.
The Authors refer about their experience , exposing a comprehensive casistic developed with the use of different machines: starting with the first ultrasonic liposuction performed with neurosurgical instruments, to follow with 1st generation devices for lipolisis , until the recent sophisticated machines that allow a more wide use of the UAL.
The results of the studies done in these years with biochemical and morphologic techniques on some peculiar aspects of UAL versus traditional techniques are shown
UAL Report on 14 years of clinical experiences
In the recent time the interest about UAL is greatly increased partly because with this technique it seems possible to guarantee constant and sure results, and partly because the machine manufactures have worked to make this procedure well known in a complete and full way.
With the major diffusion of the UAL the casisistic have increased too, the indications have widened, the complications began to show up, and the limit of the procedure have begun to be defined.
In these years the instrumentation constantly evolved, from the initial devices designed for plastic surgery manufactured by SMEI, until the more recent models on the actual market.
Purpose of this study is to compare the considerations made when the senior author firstly experienced UAL 14 years ago, with the actual orientations.
The Authors refer about their experience , exposing a comprehensive casistic developed with the use of different machines: starting with the first ultrasonic liposuction performed with neurosurgical instruments, to follow with 1st generation devices for lipolisis , until the recent sophisticated machines that allow a more wide use of the UAL.
The results of the studies done in these years with biochemical and morphologic techniques on some peculiar aspects of UAL versus traditional techniques are shown
Disperse yellow dye: An emerging professional sensitizer in contact allergy dermatitis
Disperse dyes are well known as common sensitizers in contact allergy dermatitis. Disperse yellow 3 is usually adopted in the textile industry for dying synthetic fibers, but is also used in hair dyes and for colouring plastic materials. We describe three cases of two males and one female patient, respectively a painter, an actor and a nursery-school teacher, who presented contact allergy dermatitis to disperse yellow 3 dye. Copyright © by BIOLIFE, s.a.s
