396 research outputs found
Tissot (R.), Lhermitte (F.) et Ducarne (B.). — Etat intellectuel des aphasiques. L’Encéphale 1963, n° 4, pp. 285-320
No full textTissot (R.), Lhermitte (F.) et Ducarne (B.). — Etat intellectuel des aphasiques. L’Encéphale 1963, n° 4, pp. 285-320. In: Bulletin de psychologie, tome 20 n°253, 1967. pp. 220-221
Increased 18F-FDG Uptake in Lhermitte-Duclos Disease With Cowden Syndrome Revealed by PET-MRI
No full textInternational audienceA 62-year-old woman, with the history of breast and colorectal cancer, presented intermittent diplopia. A cerebellar lesion was revealed by F-FDG PET-MRI without post-gadolinium enhancement, but with increased perfusion and strong F-FDG uptake. The diagnosis of Cowden syndrome with PTEN gene mutation, linked to higher risk of neoplasia and occurrence of hamartomatous lesions characteristic of the Lhermitte-Duclos disease (LDD), was confirmed by genetic investigation
Lhermitte-Duclos disease presenting with positron emission tomography-magnetic resonance fusion imaging: a case report
No full textAbstract Introduction Lhermitte-Duclos disease or dysplastic gangliocytoma of the cerebellum is an extremely rare tumor. It is a slowly enlarging mass within the cerebellar cortex. The majority of cases are diagnosed in the third or fourth decade of life. Case presentation We report the case of a 37-year-old Caucasian woman who underwent positron emission tomography-computed tomography with fluorine-18-fluorodeoxyglucose for evaluation of a solitary lung node. No pathological uptake was detected in the solitary lung node but the positron emission tomography-computed tomography of her brain showed intense tracer uptake, suggestive of a malignant neoplasm, in a mass in her left cerebellar lobe. Our patient had experienced two years of occipital headache and movement disorder. Subsequently, magnetic resonance imaging was performed with contrast agent administration, showing a large subtentorial mass in her left cerebellar hemisphere, with compression and dislocation of the fourth ventricle. Metabolic data provided by positron emission tomography and morphological magnetic resonance imaging views were fused in post-processing, allowing a diagnosis of dysplastic gangliocytoma with increased glucose metabolism. Total resection of the tumor was performed and histological examination confirmed the diagnosis of Lhermitte-Duclos disease. Conclusions Our case indicates that increased uptake of fluorine-18-fluorodeoxyglucose may be misinterpreted as a neoplastic process in the evaluation of patients with Lhermitte-Duclos disease, but supports the usefulness of integrated positron emission tomography-magnetic resonance imaging in the exact pathophysiologic explanation of this disease and in making the correct diagnosis. However, an accurate physical examination and exact knowledge of clinical data is of the utmost importance.</p
Fluorodeoxyglucose and methionine uptake in Lhermitte-Duclos disease: case report.
No full textOBJECTIVE AND IMPORTANCE: Lhermitte-Duclos disease (LDD) represents a focally indolent dysplastic growth of the cerebellar cortex. The 106 cases reported previously in the literature show an extremely slow evolution, and the operative indications and techniques for this disease entity are still controversial. The authors present the first case of LDD studied with positron emission tomography using the labeled tracers [(18)F]2-fluoro-2-deoxy-d-glucose ([(18)F]FDG) and (11)C-labeled methionine ([(11)C]Met) to study the glucose and protein metabolism of the lesion. CLINICAL PRESENTATION: A 40-year-old woman suddenly became unconscious then completely recovered 5 minutes later. Magnetic resonance imaging of her brain showed a well-delineated 10 x 5-cm abnormal area with enlarged cerebellar folia, which led to the diagnosis of LDD. TECHNIQUE: On positron emission tomographic scans, [(18)F]FDG and [(11)C]Met uptake in the normal cerebral and cerebellar cortex appeared higher than normal, reaching levels found in patients with primary malignant brain tumors. Moreover, the uptake of both tracers was heterogeneous, in contrast to the homogeneous uptake visualized on magnetic resonance imaging scans. The areas of greatest [(11)C]Met and [(18)F]FDG uptake were discordant. Some areas of greater than normal [(18)F]FDG uptake corresponded to areas of moderate or low [(11)C]Met uptake. Because of the important mass effect in the posterior fossa, total surgical resection was performed. A histological examination confirmed the diagnosis of LDD. CONCLUSION: This first reported metabolic study of LDD supports the view that LDD is an active and evolving disease. These data should prompt reevaluation of the indications for surgery in patients with this disease as well as the timing of surgery.Case ReportsJournal Articleinfo:eu-repo/semantics/publishe
Science et foi, par P. Chauchard, R. Chauvin, O. Costa de Beauregard, D. Dubarle, O. P., A. George, P. Germain, J.-L. Kahn, R. Lavocat, P. Lejay, S. J., R. Lennuier, L. Leprince-Ringuet, J. Lhermitte, G. Mangenot, M. Polonovski, P. Ricœur, Ph. Roqueplo, O. P., F. Russo, S. J
No full textRobert Jean-Dominique. Science et foi, par P. Chauchard, R. Chauvin, O. Costa de Beauregard, D. Dubarle, O. P., A. George, P. Germain, J.-L. Kahn, R. Lavocat, P. Lejay, S. J., R. Lennuier, L. Leprince-Ringuet, J. Lhermitte, G. Mangenot, M. Polonovski, P. Ricœur, Ph. Roqueplo, O. P., F. Russo, S. J. In: Revue Philosophique de Louvain. Troisième série, tome 63, n°78, 1965. p. 304
Œuvres poétiques de Boileau-Despréaux, avec une introduction et des notes par F. Brunetière. Édition d’après Mme Madeleine Lemaire, MM. Bida, Bonnat, G. Boulanger, Cabanel, Chapu, Chevignard, Delort, Flameng, Français, Galland, Gérome, Hédouin, Heilbuth, J. -P. Laurens, J. Le Blant, Lhermitte, Maignan, L.-O. Merson, Vibert (Paris, Hachette et Cie)
No full textArvert Franck d'. Œuvres poétiques de Boileau-Despréaux, avec une introduction et des notes par F. Brunetière. Édition d’après Mme Madeleine Lemaire, MM. Bida, Bonnat, G. Boulanger, Cabanel, Chapu, Chevignard, Delort, Flameng, Français, Galland, Gérome, Hédouin, Heilbuth, J. -P. Laurens, J. Le Blant, Lhermitte, Maignan, L.-O. Merson, Vibert (Paris, Hachette et Cie). In: Revue internationale de l'enseignement, tome 18, Juillet-Décembre 1889. p. 651
The origins of utilization behaviour
No full textUtilization behaviour has previously been described clinically by Lhermitte (1983). An experimental investigation is reported of utilization behaviour in a patient with a localized inferior medial bifrontal lesion. The patient picked up and used irrelevant objects not only when placed directly in front of him—the procedure developed by Lhermitte—but also when he had been instructed to carry out other tasks and his attention had not been directed to the objects. The behaviour occurred most frequently in the brief intervals between tasks, and more often when auditory-verbal rather than visuomotor tasks were being performed. The results are interpreted within an information-processing model of frontal lobe function. A differentiation is made between two forms of utilization behaviour—an 'incidental ' form, as exhibited by the patient, and an 'induced' form where it occurs only when Lhermitte's procedure is adopted
Central Nervous System Siderosis Associated with Multiple Cerebral Aneurysms: Literature Review and Description of an Additional Case
No full textBackground: Superficial siderosis (SS) of the central nervous system is a rare disease characterized by deposition of hemosiderin along the leptomeninges due to chronic or recurrent bleeding into the subarachnoid space. The association of unruptured intracranial aneurysm (IA) and cortical SS is quite rare. Methods: A systematic literature review to assess possible commonalities and/or differences of previous reported cases was undertaken. We report an additional case from our institution. Results: A 40-year-old woman presented with a history of generalized seizures over the past year. There was no clinical history suggestive of aneurysm rupture. Magnetic resonance imaging revealed 2 aneurysms of the right middle cerebral artery (MCA) bifurcation associated with hemosiderin deposition along the right sylvian fissure and a third aneurysm of the left MCA bifurcation. Magnetic resonance imaging showed wall enhancing thickening of the larger right MCA aneurysm. The patient underwent surgical clipping of all 3 MCA aneurysms in a staged procedure. Histological examination revealed hemosiderin deposits within the aneurysm wall and surrounding gliosis. Conclusions: Our literature review found 24 reported cases of unruptured IA associated with cortical SS. The possible source for leakages could be neovessels visible in IA walls. The case reported illustrates an uncommon presentation of recurrent bleeding from an IA as a source of SS. The presence of an apparently unruptured IA surrounded by cortical SS on imaging studies is of high relevance as this should be considered a sign of aneurysm wall instability and should indicate prompt treatment
Lhermitte-Duclos disease (dysplastic cerebellar gangliocytoma): Review of the literature
No full textOBJECTIVES: Lhermitte-Duclos disease (LDD), or dysplastic gangliocytoma of the cerebellum is a rare benign unilateral mass of the cerebellar cortex, characterized by a disarrangement of the normal cerebellar laminar cytoarchitecture and circumscribed enlargement of cerebellar folia. LDD was recently considered to be part of a multiple hamartoma-neoplasia syndrome [Cowden disease (CD)]. The debate whether LDD represents a neoplastic or hamartomatous lesion is still in progress. METHODS: The aim of the present study is to answer this question with review of the literature emphasize on clinical presentation, radiologic findings, surgical procedures, and histopathologic features of LDD. RESULTS: LDD most frequently presents in the third and fourth decades of life, but the age at clinical manifestation ranges from the neonatal period to the seventh decade. The initial presentation of LDD, similar to other posterior fossa tumors, includes increased intracranial pressure, vomiting, intermittent headache, cerebellar dysfunction, and noncommunicating hydrocephalus. Magnetic resonance imaging is the diagnostic modality and reveals characteristic usually nonenhancing gyriform patterns with enlargement of cerebellar folia. Surgical excision is a therapeutic procedure generally performed. The histopathologic findings of LDD include thickening of the molecular layer, which is occupied by abnormal ganglion cells, absence of the Purkinje cell layer, and hypertrophy of the granule cell layer. CONCLUSIONS: LDD is an unusual hamartomatous lesion of the cerebellar cortex, which can be associated with CD. When the diagnosis of either one of these 2 disorders is established, it is imperative to search for the other disease, to detect early malignant lesions that occur in CD. © 2007 Lippincott Williams & Wilkins, Inc
Empereurs sans empire : Romulus le grand (F. Dürrenmatt) et L’empereur d’occident (P. Michon)
No full text- …
