2,062 research outputs found
Bayesian multi-modal model comparison: a case study on the generators of the spike and the wave in generalized spike–wave complexes
No full textWe present a novel approach to assess the networks involved in the generation of spontaneous pathological brain activity based on multi-modal imaging data. We propose to use probabilistic fMRI-constrained EEG source reconstruction as a complement to EEG-correlated fMRI analysis to disambiguate between networks that co-occur at the fMRI time resolution. The method is based on Bayesian model comparison, where the different models correspond to different combinations of fMRI-activated (or deactivated) cortical clusters. By computing the model evidence (or marginal likelihood) of each and every candidate source space partition, we can infer the most probable set of fMRI regions that has generated a given EEG scalp data window. We illustrate the method using EEG-correlated fMRI data acquired in a patient with ictal generalized spike–wave (GSW) discharges, to examine whether different networks are involved in the generation of the spike and the wave components, respectively. To this effect, we compared a family of 128 EEG source models, based on the combinations of seven regions haemodynamically involved (deactivated) during a prolonged ictal GSW discharge, namely: bilateral precuneus, bilateral medial frontal gyrus, bilateral middle temporal gyrus, and right cuneus. Bayesian model comparison has revealed the most likely model associated with the spike component to consist of a prefrontal region and bilateral temporal–parietal regions and the most likely model associated with the wave component to comprise the same temporal–parietal regions only. The result supports the hypothesis of different neurophysiological mechanisms underlying the generation of the spike versus wave components of GSW discharges
C. Bessy, F. Chateauraynaud, Experts et faussaires. Pour une sociologie de la perception
No full textLemieux Cyril. C. Bessy, F. Chateauraynaud, Experts et faussaires. Pour une sociologie de la perception. In: Politix, vol. 8, n°31, Troisième trimestre 1995. Parler en public (2). Dispositifs contemporains, sous la direction de Dominique Cardon, Jean-Philippe Heurtin et Cyril Lemieux. pp. 228-232
Homage to Jean Paul Lemieux = Hommage à Jean Paul Lemieux
No full text"Jean Paul Le mieux was the author of works that continue to fascinate us and whose style and technique set them apart from the major movements of contemporary art. The appeal of his singular practice has been confirmed by its huge popular success. Yet beyond the immediate charm of some of his subjects lies this painter's eloquent vision of our vast spaces, our northern sensibility and our collective soul - a soul torn between the nostalgia for the past and an unknowable future. Through his introspective nature, Lemieux was able to vividly capture in his work the solitude of individual human existence, thus giving it a universal dimension. For all these reasons, The National Gallery of Canada and the Musée national des beaux-arts du Québec have enthusiastically joined forces to mark the hundredth anniversary of Lemieux's birth with a commemorative exhibition." -- p. [8]
Helen Coe Lemieux Scrapbook
No full textThese items are images from digital and paper sources that were gathered for the Toledo Women Lawyers History Project (TWLHP). The material in this folder focuses on the career of Helen Coe Lemieux (1942-2008). She began practicing law in the mid 1970s and maintained a law office in downtown Maumee, practicing in Lucas and Wood Counties for over 35 years. Images in this folder include a memorial by Gary F. Kuns, and two obituaries
McGill sea ice model
No full text<p>Version of the McGill sea ice model used for the numerical experiments described in the manuscript :</p>
<p>"On the calculation of normalized viscous-plastic sea ice stresses" by JF Lemieux and F. Dupont (submitted to GMD).</p>
"Et here we go again, c'est reparti mon kiki!"- Voyage et identités dans "Toutes mes solitudes!" de Marie-Christine Lemieux-Couture
No full textAnalyse du roman de Marie-Christine Lemieux-Couture à partir de l'itinéraire de la Transcanadienne
Modelling large motion events in fMRI studies of patients with epilepsy
No full textEEG-correlated fMRI can provide localisation information on the generators of epileptiform discharges in patients with focal epilepsy. To increase the technique's clinical potential, it is important to consider ways of optimising the yield of each experiment while minimizing the risk of false-positive activation. Head motion can lead to severe image degradation and result in false-positive activation and is usually worse in patients than in healthy subjects. We performed general linear model fMRI data analysis on simultaneous EEG–fMRI data acquired in 34 cases with focal epilepsy. Signal changes associated with large inter-scan motion events (head jerks) were modelled using modified design matrices that include ‘scan nulling’ regressors. We evaluated the efficacy of this approach by mapping the proportion of the brain for which F-tests across the additional regressors were significant. In 95% of cases, there was a significant effect of motion in 50% of the brain or greater; for the scan nulling effect, the proportion was 36%; this effect was predominantly in the neocortex. We conclude that careful consideration of the motion-related effects in fMRI studies of patients with epilepsy is essential and that the proposed approach can be effective
Multimodal imaging of human brain activity: rational, biophysical aspects and modes of integration
No full textUntil relatively recently the vast majority of imaging and electrophysiological studies of human brain activity have relied on single-modality measurements usually correlated with readily observable or experimentally modified behavioural or brain state patterns. Multi-modal imaging is the concept of bringing together observations or measurements from different instruments. We discuss the aims of multi-modal imaging and the ways in which it can be accomplished using representative applications. Given the importance of haemodynamic and electrophysiological signals in current multi-modal imaging applications, we also review some of the basic physiology relevant to understanding their relationship
Etude de la perception des habiletés chez les infirmières comme explication partielle des difficultés de la socialisation professionnelle : rapport de recherche présenté à l'Université du Québec à Trois-Rivières /
No full textDécembre 1989Bibliogr.: f. 94-95Notes (part. bibliogr.) au bas des f
Differences in waiting times for elective admissions in NSW public hospitals: A decomposition analysis by non-clinical factors. CHERE Working Paper 2010/7
No full textIn the Australian public health system, access to elective surgery is rationed through provision of health care services, it is generally assumed that a patient?s waiting time and locations. In this paper we undertake Oaxaca-Blinder and DiNardo-Fortin-Lemieux decompostition analyses to attribute variation in waiting time to a component explained by clinical need and to differential treatment effects. The latter have an interpretation as discrimination, since treatments vary by non-clinical factors such as socioeconomic status. Using data from public patients in NSW public hospitals in 2004-2005, we find socioeconomically advantaged patients, patients in remote areas, and patients in several Area Health Services have shorter waiting times than their clinical comparable counterparts. Furthermore, the discrimination effect dominates clinical admission if their treatments are delayed. This finding has policy implications for the current operation of waiting lists and order of admission and for the design of equitable quality targets for public hospitals.Public hospitals, waiting times, discrimination, decomposition analysis
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