422 research outputs found
FIGURE. Basidiocarps of species of Agaricales in Panama. a. Asterophora parasitica (PAN180) on decayed basidiocarp of Russula sp. b–c. Campanophyllum probiscideum. b. On bark of a standing tree (KaiR434). c. From above and below (KaiR434). d–e. Rhodocollybia tablensis. d. (KaiR484). e. (PAN238). f. Cantharocybe brunneovelutina (PAN260). g. Pluteus hongoi (PAN413). h. Tetrapyrgos atrocyanea (KaiR395). Bars a = 1 cm, b, c, f, g = 2 cm, d, e = 5 cm, h = 0.5 cm. a, f, g Photos by H. Lotz-Winter. b, c, d, h Photos by K. Reschke. e Photo by O. Koukol. in New and interesting species of Agaricomycetes from Panama
No full textFIGURE. Basidiocarps of species of Agaricales in Panama. a. Asterophora parasitica (PAN180) on decayed basidiocarp of Russula sp. b–c. Campanophyllum probiscideum. b. On bark of a standing tree (KaiR434). c. From above and below (KaiR434). d–e. Rhodocollybia tablensis. d. (KaiR484). e. (PAN238). f. Cantharocybe brunneovelutina (PAN260). g. Pluteus hongoi (PAN413). h. Tetrapyrgos atrocyanea (KaiR395). Bars a = 1 cm, b, c, f, g = 2 cm, d, e = 5 cm, h = 0.5 cm. a, f, g Photos by H. Lotz-Winter. b, c, d, h Photos by K. Reschke. e Photo by O. Koukol.Published as part of Reschke, Kai, Lotz-Winter, Hermine, Fischer, Christian W., Hofmann, Tina A. & Piepenbring, Meike, 2021, New and interesting species of Agaricomycetes from Panama, pp. 1-26 in Phytotaxa 529 (1) on page 15, DOI: 10.11646/phytotaxa.529.1.1, http://zenodo.org/record/581416
FIGURE. Microscopic structures of Rhodocollybia tablensis a, b, e, f (PAN238), c, d (KaiR343) a. Basidia. b. Basidiospores. c. Cheilocystidia. d. Pleurocystidia. e. Stipitipellis with caulocystidia. f. Pileipellis with terminal cells. Bars a, b and c = 10 µm, d, e and f = 20 µm. Drawings by H. Lotz-Winter. in New and interesting species of Agaricomycetes from Panama
No full textFIGURE. Microscopic structures of Rhodocollybia tablensis a, b, e, f (PAN238), c, d (KaiR343) a. Basidia. b. Basidiospores. c. Cheilocystidia. d. Pleurocystidia. e. Stipitipellis with caulocystidia. f. Pileipellis with terminal cells. Bars a, b and c = 10 µm, d, e and f = 20 µm. Drawings by H. Lotz-Winter.Published as part of Reschke, Kai, Lotz-Winter, Hermine, Fischer, Christian W., Hofmann, Tina A. & Piepenbring, Meike, 2021, New and interesting species of Agaricomycetes from Panama, pp. 1-26 in Phytotaxa 529 (1) on page 16, DOI: 10.11646/phytotaxa.529.1.1, http://zenodo.org/record/581416
Space Flight and Manual Control: Implications for Sensorimotor Function on Future Missions
No full textControl of vehicles, and other complex mechanical motion systems, is a high-level integrative function of the central nervous system (CNS) that requires good visual acuity, eye-hand coordination, spatial (and, in some cases, geographic) orientation perception, and cognitive function. Existing evidence from space flight research (Paloski et.al., 2008, Clement and Reschke 2008, Reschke et al., 2007) demonstrates that the function of each of these systems is altered by removing (and subsequently by reintroducing) a gravitational field that can be sensed by vestibular, proprioceptive, and haptic receptors and used by the CNS for spatial orientation, navigation, and coordination of movements. Furthermore, much of the operational performance data collected as a function of space flight has not been available for independent analysis, and those data that have been reviewed are equivocal owing to uncontrolled environmental and/or engineering factors. Thus, our current understanding, when it comes to manual control, is limited primarily to a review of those situations where manual control has been a factor. One of the simplest approaches to the manual control problem is to review shuttle landing data. See the Figure below for those landing for which we have Shuttle velocities over the runway threshold
Fig. 1 in Occurrence and chemotaxonomical analysis of amatoxins in Lepiota spp. (Agaricales)
No full textFig. 1. Fruiting bodies of Lepiota spp. (Agaricales) used for the present analysis of amatoxins. A L. elaiophylla (SeSa 23), scale bar: 2 cm. B L. brunneoincarnata (SeSa 4), scale bar: 3 cm. C L. felina (SeSa 7), scale bar: 1.5 cm. D L. aspera (SeSa 14), scale bar: 3 cm. E L. magnispora (S 21), scale bar: 1.8 cm. F L. cristata (SeSa 1), scale bar: 3.8 cm. G L. oreadiformis, scale bar: 4 cm. H L. fuscovinacea (SeSa 8), scale bar: 3.5 cm.Published as part of Sarawi, Sepas, Shi, Yan-Ni, Lotz-Winter, Hermine, Reschke, Kai, Bode, Helge B. & Piepenbring, Meike, 2022, Occurrence and chemotaxonomical analysis of amatoxins in Lepiota spp. (Agaricales), pp. 1-8 in Phytochemistry (113069) 195 on page 3, DOI: 10.1016/j.phytochem.2021.113069, http://zenodo.org/record/823540
Autoimmune gastritis in autoimmune thyroid disease
No full textBackground Autoimmune gastritis leads to oxyntic gastric atrophy, a condition at increased risk for gastric cancer. Autoimmune gastritis in conjunction with autoimmune thyroid disease has been reported previously. Aim In a case-control study in patients with autoimmune thyroid disease to evaluate the usefulness of serum pepsinogens for the identification of oxyntic gastric atrophy, and to determine the relationship of Helicobacter pylori with oxyntic gastric atrophy. Methods Patients with autoimmune thyroid disease (cases) and goitre (controls) were prospectively enrolled in the study. Pepsinogen (PG) I levels â¤25 Î1⁄4g/mL and PG I/II ratio â¤3 were indicative for oxyntic gastric atrophy. Antibodies against H. pylori, CagA and parietal cells were also determined. Esophagogastroduodenoscopy with biopsies was offered to patients with serological oxyntic gastric atrophy. Results In total, 34 autoimmune thyroid disease patients and 30 controls were enrolled. Serological oxyntic gastric atrophy was present only in autoimmune thyroid disease patients (8/34, 23.5%, OR 8.3, 95% CI = 1.9-36.2). In all eight patients oxyntic gastric atrophy was confirmed by histology. OLGA stage I, II, III and IV was described in 0%, 33%, 50% and 17% of the cases, respectively. About, 89% and 11% of oxyntic gastric atrophy patients were seropositive for antibodies against parietal cells or H. pylori infection, respectively. Gastric atrophy involved the angulus/antrum in 50% of patients with autoimmune gastritis. Conclusions The seroprevalence of oxyntic gastric atrophy is high in patients with autoimmune thyroid disease, and testing of serum pepsinogens should be included in the clinical assessment of these patients. H. pylori infection is unlikely to be a principal factor in the pathogenesis of oxyntic gastric atrophy in patients with autoimmune thyroid disease. In autoimmune gastritis, gastric atrophy can spread from the oxyntic towards the antral mucosa
Vergessen als der grösste Affekt:Affekt, Vergessen und Gerechtigkeit in <em>Vom Nutzen und Nachteil der Historie für das Leben</em>
No full textEn undersøgelse af forholdet mellem affekt og historieopfattelse i F. Nietzsches skrift om historiens nytt
The RNA binding protein ESRP1 fine-tunes the expression of pluripotency-related factors in mouse embryonic stem cells
No full textIn pluripotent stem cells, there is increasing evidence for crosstalk between post-transcriptional and transcriptional networks, offering multifold steps at which pluripotency can be controlled. In addition to well-studied transcription factors, chromatin modifiers and miRNAs, RNA-binding proteins are emerging as fundamental players in pluripotency regulation. Here, we report a new role for the RNA-binding protein ESRP1 in the control of pluripotency. Knockdown of Esrp1 in mouse embryonic stem cells induces, other than the well-documented epithelial to mesenchymal-like state, also an increase in expression of the core transcription factors Oct4, Nanog and Sox2, thereby enhancing self-renewal of these cells. Esrp1-depleted embryonic stem cells displayed impaired early differentiation in vitro and formed larger teratomas in vivo when compared to control embryonic stem cells. We also show that ESRP1 binds to Oct4 and Sox2 mRNAs and decreases their polysomal loading. ESRP1 thus acts as a physiological regulator of the finely-tuned balance between self-renewal and commitment to a restricted developmental fate. Importantly, both mouse and human epithelial stem cells highly express ESRP1, pinpointing the importance of this RNA-binding protein in stem cell biology. © 2013 Fagoonee et al
Collaboration for rare diabetes: understanding new treatment options for Wolfram syndrome
No full textBackground: Wolfram Syndrome is a very rare genetic disease causing diabetes mellitus, blindness, deafness, diabetes insipidus, and progressive brainstem degeneration. Neurologic symptoms of affected patients include ataxia, sleep apnea, loss of bladder control, dysphagia, loss of taste, and accompanying psychiatric symptoms as a sign of progressive neurodegeneration. Its genetic cause is mainly biallelic mutations of the Wolframin endoplasmatic reticulum transmembrane glycoprotein gene Wfs1. These result in increased ER stress, which in turn induces apoptosis and leads to the depletion of the corresponding cells and a loss of their physiological functions. Though diabetes mellitus is mostly treated by insulin, there is still no proven cure for the disease in general. It leads to premature death in affected individuals—usually within the 4th decade of live. Current research and treatment trials: Clinical studies are currently being conducted at various locations worldwide to test a therapy for the disease using various approaches. Potentail of virtual netowrking: As rare diseases in general represent a major challenge for individual clinicians and researchers due to the rarity of diagnosis, the lack of evidence and of value of existing research, international cooperation, coordination and networking leading to an alignment of different stakeholders is necessary to support patients and increase knowledge about these diseases, like wolfram syndrome. Conclusion: ENDO-ERN and EURRECA are two EU-funded networks that aim to promote knowledge sharing, education and research on rare endocrine diseases
1928 Football Team
No full textSepia photograph, mounted.Back - J. Cuthbertson, F. Von Doussa, R.E. Oldfield, C.G.S. Kimber, J.C. Heggie, H. Reschke, Mr. S.E. Whicker; Middle - D. Fulton, J. McM. Glynn, J.O. Tuckwell, R.B. Postle, R.N. Mellor, Mr. T.A. Cole, Mr J.L. Williams, A.C. Hooper; Front - T.V. Winnall, L.V. Spencer, Mr. W.R. Birks (Principal), W.E. Meier (Captain), R. Baker (Football Master), D.A. Humphris (Vice-Capt), A.K. Drew
The wandering logic intelligence
No full textTHE WANDERING LOGIC INTELLIGENCE
A HYPERACTIVE APPROACH TO NETWORK EVOLUTION AND ITS APPLICATION
TO ADAPTIVE MOBILE MULTIMEDIA COMMUNICATIONS
Plamen L. Simeonov
Tag der Einreichung: 19.06.2002
Tag der Verteidigung: 18.12.2002
Gutachter:
1. Univ.-Prof. Dr.-Ing. habil. Dietrich Reschke, Technische Universität Ilmenau
2. Prof. Dr.-Ing. habil. Jörg Lange, Siemens AG, Berlin
3. Univ.-Prof. Dr. Kenneth J. Turner, University of Stirling, Scotland, UK
Zusammenfassung
Diese Dissertation ist wie folgt organisiert.
Kapitel 1 beschreibt den Rahmen der Dissertation: das Forschungsgebiet, die Motivation
für diese Arbeit, die Beiträge des Autors und die Darstellungsstruktur.
Kapitel 2 beinhaltet die Übersicht und die Klassifikation der einzelnen Bereiche,
die Gegenstand der Dissertation sind. Sektion 2.4 untersucht die heutigen Forschungsgebiete
in der drahtlosen mobilen Telekommunikation mit dem Ziel, die Anwendungsdomäne für diese
Dissertationsarbeit zu identifizieren.
Kapitel 3 ist den Aktiven Netzen (AN) gewidmet, dem eigentlichen Fundament der Dissertation.
Es beginnt mit einer Einführung in die Entstehung der aktiven Software-Architekturen. Weiter
beschreibt es die Herausforderungen, denen sie sich in der modernen Telekommunikationswelt
stellen müssen. Abschnitt 3.2 des Kapitels beinhaltet das konzeptionelle Paradigma der Aktiven
Netze: das ihnen zugrunde liegende Referenz-Modell. Weiter folgt eine Zusammenfassung der
Forschungsvorhaben und der gegenwärtigen Implementationsrahmen. Abschnitt 3.3 ist den
AN-Architekturen gewidmet und identifiziert Muster und Tendenzen in der AN-Forschung,
um eine Genealogie der Idee des Wandernden Netzes abzuleiten. Das Exposé enthält eine
kurze Übersicht der Enabling-Technologies für Aktive Netzwerke, indem es einige
Schlüsselvorteile betont. Abschnitt 3.4 umschreibt die AN-Forschungsdomäne mit Fokus
auf verschiedenen Anwendungen. Abschnitt 3.5 wichtet die Hauptrichtungen in der AN-Forschung.
Insbesondere werden die Anwendungen von Aktiven Netzen in der mobilen Telekommunikation betrachtet.
Schließlich liefert Abschnitt 3.6. eine allgemeine Analyse und Diskussion der AN-Methode einschl.
eines Vergleichs der Netzprogrammierungsarten. Einen Ausblick für die weitere Forschung und
eine Zusammenfassung mit entsprechenden Schlussfolgerungen geben die Abschnitte 3.7, 3.8 und 3.9.
Kapitel 4 ist der Hardware-Seite der Hypothese über das Wandernde Netzwerk gewidmet. Einige
Spezialthemen des Rekonfigurierbaren Computings, die bei Micro- (Chip) und Makro- (Computer)
Komponenten-Architekturen in den heutigen Netzen genutzt werden, werden detailliert präsentiert.
Besondere Aufmerksamkeit wird im Abschnitt 4.2 den Auswirkungen der Aktiven Netzwerke und des
Rekonfigurierbaren-Computings auf die Definition der heutigen Netzinfrastrukturen gewidmet.
Hier werden einige offene Fragen aus den vorangegangenen drei Kapiteln erörtert, wie das Mischen
von aktiven und passiven Flows, Flexibilität vs. Sicherheit und Konfiguration vs. Encapsulation.
Kapitel 5 stellt den Kern der Dissertation, die Wandernde-Logik-Intelligenz (WLI), dar. Das Exposé
beschreibt die allgemeinen Anforderungen und die zukünftigen Perspektiven in Aktiven Netzen und
verwandten Disziplinen, um die Architekturbasis der WLI-Methode zu definieren. Die Argumentation
und die Definition der WLI-Architektur ist in Abschnitt 5.2 gegeben. Danach folgen in Abschnitt
5.3 die vier Prinzipien des Wandernden Netzes: Dualistische Kongruenz, Multidimensionale Rückkopplung,
Selbst-Referenz (Selbstbezug) und Pulsierende Metamorphose.
Kapitel 6 demonstriert die Angemessenheit der WLI-Methode in einer Fallstudie mit der formalen
Spezifikation und dem Test eines Algorithmus’ für aktives mobiles ad-hoc Routing in der TLA+-Technik
(Temporal Logic of Actions).
Schliesslich liefert Kapitel 7 eine allgemeine Auswertung der Thesen dieser Dissertation, atwortet
einigen Abschlußfragen und beendet diese Arbeit mit Empfehlungen für die zukunftige Forschung.This thesis is organized as follows.
Chapter 1 introduces the overall frame of the thesis: field of research, motivation, author?s contributions and structure.
Chapter 2 presents an introduction and classification of the particular areas involved in this dissertation. Section 2.4 reviews the present research areas in wireless mobile communications with the objective to identify the application domain frame for this thesis work.
Chapter 3 is devoted to Active Networks (AN). We build this thesis work on this fundament. The review begins with introducing the reasons for the emergence of active software architectures followed by the challenges in modern communications to which they are exposed. Then, section 3.2 describes the conceptual paradigm of Active Networking, the underlying Reference Model, and a summary of the research approaches and the current implementation framework. Section 3.3 is dedicated to the active network architectures with the goal to identify the patterns and trends in AN research
in order to derive a genealogy of the upcoming idea of the Wandering Network. The expose includes a short review of the enabling technologies for active networking highlighting their key advantages. Section 3.4 reviews the domains
of AN research with a focus on a variety of applications. Section 3.5 identifies the mainstream directions in AN research. A special attention is dedicated to the application of active networks in mobile communications. Finally, section 3.6 provides an overall analysis and discussion of the active network approach including a comparison of the network programming approaches. An outlook for further research and a summary with conclusions are given in sections 3.7, 3.8 and 3.9 respectively.
Chapter 4 is devoted to the "hardware" branch of the Wandering Network hypothesis. Here we presents in detail some specific issues in Reconfigurable Computing as related to micro (chip) and macro (computer) component architectures used in present day networks. In section 4.2 special attention is devoted to the implications of active networking and
reconfiguration in defining today's network infrastructures. Here we address some open questions from the previous three chapters: mixing active and passive flows, flexibility vs. security and configuring vs. encapsulation.
Chapter 5 presents the kernel of this thesis? research, the Wandering Logic Intelligence (WLI).
The exposé describes the general requirements and the future directions in active networking and related disciplines in order to define the architectural base of the WLI approach. The argumentation and the definition of the WLI architecture is given in section 5.2, followed by the four principles of the Wandering Network - Dualistic Congruence, Multidimensional Feedback, Self-Reference, and Pulsating Metamorphosis -, in section 5.3.
Chapter 6 demonstrates the suitability of the WLI approach in a case study with the formal specification and test of an algorithm for active mobile ad-hoc routing in TLA+, the Temporal Logic of Actions technique.
Finally, chapter 7 provides an overall evaluation of the thesis objectives, answers some final questions and concludes this work with directions for further research
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