71 research outputs found

    Business Organization and Coordination in Marketing Specialty Hogs: A Comparative Analysis of Two Firms from Iowa

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    We study business organization and coordination of specialty-market hog production using a comparative analysis of two Iowa pork niche-marketing firms.� We describe and analyze each firm's management of five key organizational challenges: planning and logistics, quality assurance, process verification and management of "credence attributes," business structure, and profit sharing.� Although each firm is engaged in essentially the same activity, there are substantial differences across the two firms in the way production and marketing are coordinated.� These differences are partly explained by the relative size and age of each firm, thus highlighting the importance of organizational evolution in agricultural markets, but are also partly the result of a formal organizational separation between marketing and production activities in one of the firms.specialty hogs

    Projekt JAI-MARO Waterkrachtcentrale

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    Het verslag bestaat uit 3 delen: Deel A: vooronderzoek - probleem definitie en inleiding. Deel B: Ondergrondse centrale -Energieberekeningen. Deel C: Ondergrondse centrale -Globale dirnensionering van enige onderdelen.Hydraulic EngineeringCivil Engineering and Geoscience

    Can smartphones and tablets improve the management of childhood illness in Tanzania? A qualitative study from a primary health care worker’s perspective

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    The impact of the Integrated Management of Childhood Illness (IMCI) strategy has been less than anticipated because of poor uptake. Electronic algorithms have the potential to improve quality of health care in children. However, feasibility studies about the use of electronic protocols on mobile devices over time are limited. This study investigated constraining as well as facilitating factors that influence the uptake of a new electronic Algorithm for Management of Childhood Illness (ALMANACH) among primary health workers in Dar es Salaam, Tanzania.; A qualitative approach was applied using in-depth interviews and focus group discussions with altogether 40 primary health care workers from 6 public primary health facilities in the three municipalities of Dar es Salaam, Tanzania. Health worker's perceptions related to factors facilitating or constraining the uptake of the electronic ALMANACH were identified.; In general, the ALMANACH was assessed positively. The majority of the respondents felt comfortable to use the devices and stated that patient's trust was not affected. Most health workers said that the ALMANACH simplified their work, reduced antibiotic prescription and gave correct classification and treatment for common causes of childhood illnesses. Few HWs reported technical challenges using the devices and complained about having had difficulties in typing. Majority of the respondents stated that the devices increased the consultation duration compared to routine practice. In addition, health system barriers such as lack of staff, lack of medicine and lack of financial motivation were identified as key reasons for the low uptake of the devices.; The ALMANACH built on electronic devices was perceived to be a powerful and useful tool. However, health system challenges influenced the uptake of the devices in the selected health facilities

    Implementasi Alokasi Dana Desa dalam Pemberdayaan Masyarakat Di Desa Mudung Darat Kecamatan Maro Sebo Kabupaten Muaro Jambi

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    According to the results of observations made by the author in the village of Mudung Darat, Maro Sebo District, Muaro Jambi Regency, the management of village funds, especially the Village Fund Allocation, has not been implemented optimally, especially in the planning and implementation stages of the village fund allocation. This study aims to determine and analyze the Implementation of Village Fund Allocation in Community Empowerment in Mudung Darat Village, Muaro Jambi Regency, to identify and analyze the constraints of Village Fund Allocation Implementation in Community Empowerment in Mudung Darat Village, Muaro Jambi Regency and to identify and analyze the efforts made to overcome the obstacles in implementing Village Fund Allocation in Community Empowerment in Mudung Darat Village, Muaro Regency. This type of research used in this paper is empirical juridical research. The implementation of ADD in carrying out Public Expenditures and community empowerment has not been carried out optimally. The obstacles faced in implementing the allocation are the lack of understanding of the Village Government apparatus regarding the main tasks and functions and the lack of information and socialization to the community. Quality of Human Resources (HR) That Has Not Supported the Management and Implementation of Village Fund Allocation. The culture of mutual cooperation among the people of Mudung Darat Village is starting to fade, and the culture of mutual cooperation is the hallmark of a village

    Bioengineered Skin in Psoriasis Modeling: Investigation of Automated Injection Molding of Dermo-Epidermal Models as compared with Benchmark Manual Fabrication.  

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    Bioengineered skin was initially developed for clinical application in reconstructive surgery, but nowadays it is also considered as a suitable skin model for research. Research applications range from assessment of cosmetic and pharmaceutical products to the modeling of pathological skin conditions. For example, psoriasis is a complicated skin disease that strongly concerns the scientific community because of its unclear pathogenesis and the current inability to cure it. The Pharmacogenomics Lab of ETH has been working on the development of psoriatic skin models in order to investigate the driving mechanisms of the disease and to later implement high-throughput drug screening to explore treatment possibilities. However, the manual production into transwell inserts results in unstable, self-contracting and inconsistent skin models, pain points that the Pharmacogenomics Lab would like to eliminate. A recent collaboration between the Product Development Group and the Pharmacogenomics Lab has been recently initiated in an attempt to standardize the fabrication of the psoriatic skin models. For this purpose, this Master Thesis focused on the investigation of the potentials and limitations of automated injection molding, a method developed by the Product Development Group, in the generation of consistent and representative dermo-epidermal models for psoriatic skin. After a series of experiments, it was seen that in-mold fabrication achieves homogeneous and consistent dermal hydrogels that maintain their dimensions throughout the whole cultivation period regardless of the collagen concentration employed for the dermal matrix, while automated injection molding allows the utilization of collagen concentrations higher than the unstable 5mg/ml, traditionally used in the manual fabrication method. All collagen concentrations exhibited similar biological performance, but the optimum fibroblasts viability was achieved in case of 5mg/mL, meaning that the whole injection molding process should be faster and even simpler to fully prevail over manual fabrication of skin models and better fit the requirements of skin disease research. Keratinocytes viability and differentiation was similar for all mold designs, all collagen concentrations and both fabrication methods. Development of a first psoriatic model, consisting of psoriatic fibroblasts and healthy keratinocytes, did not show any direct effect of diseased fibroblasts on keratinocytes proliferation and differentiation as the epidermal layer of the psoriatic model was very similar to this one of the healthy model.Evaluation of the automated seeding of keratinocytes for further standardization of the process and elongation of the psoriatic model’s cultivation period for a more thorough study should be the next steps. In the long-term, incorporation of all the psoriasis-related cells and molecules in a simple and fast way, as well as further advancements in the mold design to facilitate a direct high-throughput drug screening should be considered.Biomedical Engineering | Biomaterials and Tissue Biomechanic

    Постмодернистское направление в новогреческой литературе (на примере двух романов Маро Дука)

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    В статье рассматриваются постмодернистские черты двух романов Маро Дука, проявляющиеся в системе персонажей, композиционной структуре, категории автора, временно – пространственных характеристиках.У статті розглядаються постмодерністські риси двох романів Маро Дука, особлива увага приділяється системі образів, композиційній структурі, категорії автора, часовим та просторовим характеристикам.In the article we point out the postmodern features in two novels by modern Greek writer, Maro Duka, paying peculiar attention to the system of images, the plot structure, the category of the author, the time and space characteristics

    Постмодернистское направление в новогреческой литературе (на примере двух романов Маро Дука)

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    В статье рассматриваются постмодернистские черты двух романов Маро Дука, проявляющиеся в системе персонажей, композиционной структуре, категории автора, временно – пространственных характеристиках.У статті розглядаються постмодерністські риси двох романів Маро Дука, особлива увага приділяється системі образів, композиційній структурі, категорії автора, часовим та просторовим характеристикам.In the article we point out the postmodern features in two novels by modern Greek writer, Maro Duka, paying peculiar attention to the system of images, the plot structure, the category of the author, the time and space characteristics

    IDENTIFICATION OF SMALL MOLECULES THAT REGULATE NEMATODE – ENVIRONMENT INTERACTIONS

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    173 pagesSupplemental file(s) description: Supplementary File 1.One of the central channels of nematode-environment interactions is through small molecules (non-polymeric chemical entities with a molecular mass <1000 Daltons). Nematodes release an abundance of small molecules which affect their environment, such as the ascarosides, di-deoxy sugar lipids which control the development and behavior of nematodes and other members of their environment. Through the advancement of high-resolution mass spectrometry and analysis software, we now find a wealth of other small molecules produced by nematodes which play key roles in their environmental interactions. Herein the author describes the integrated use of 2D NMR and high-resolution UHPLC-MS/MS to aid metabolomics of complex natural samples to characterize small molecules that regulate interactions between nematodes and their environment. Combining these analytical techniques with biological assay data, the author has characterized small molecules from nematodes which elicit defensive responses in other nematodes and affect microbial and nematode growth. The library of small molecules presented in this dissertation provide a new layer of structural diversity in nematodes and define a path forward in discovering other molecules of their kind. The novel small molecules shown in this thesis include - Branched chain sulfolipids (sufal/ac), molecules that cause defensive behavior in prey nematodes that appear to be linked to the development of the predator nematode’s mouth dimorphism. Cyclic sulfates (cysul), a class of metabolites unprecedented in nature, with possible epoxide precursors that suggest a straightforward biosynthetic pathway. The cyclic sulfates, unlike the branched chain sulfolipids, do not affect defensive behaviors in other nematodes, but may play a yet undiscovered role in a nematode’s interactions with its environment. Cyclopropyl lipids (cpfa), nematode derivatives of bacteriogenic metabolites which inhibit microbial growth in several species. The activity of these lipids was found to be stereochemically specific, suggesting that the effect on microbial growth may be through a signaling mechanism. Through these studies the author hopes to convey connections between small molecules created by nematodes with their environment and draw parallels with their potential effect on other organisms

    COMPARISONAL ANALYSIS OF RECEIVABLE AND TRADE DEBT BUDGETING IN MSME FINANCIAL STATEMENTS

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    In the era of the COVID-19 pandemic, this is a new challenge for MSME business actors in Indonesia. There are so many problems that occur such as reducing employees, a lot of unemployment, people who are starting to get used to living with new patterns of habits and activities such as staying at home, working from home, and studying at home. MSME actors must think hard in maintaining and making new innovations in strengthening their business for their daily needs. This study aims to analyze the financial performance or performance of Hasan STIM MSMEs on April 1, 2020 &amp; June 1, 2020. In April 2020 there was the highest increase in income. high in 2020 because this month coincides with the Eid homecoming season and school holidays. Many families, tourism buses, and even other four-wheeled land transportation use STIM services on Hasan STIM. In the financial statements of SMEs Hasan STIM does not use accounting records but through simple cash book records. Here the author analyzes as well as helps calculate how much total assets, total liabilities, total equity, total income and total net income. In this case the condition of Hasan STIM's financial statements on accounts payable and accounts receivable has experienced ups and downs, especially the impacts caused by previous needs not purchased must be purchased and soaring equipment prices caused unstable financial conditions, especially in payables and accounts receivable. The analysis used in this study is a comparison of the budget on April 1, 2020 with June 1, 2020, which shows that the financial condition of the MSME business at Hasan STIM is quite good and has increased sales in April and decreased in June. Hasan STIM's financial report shows less debt than assets and profits
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