674 research outputs found
Preliminary evidence of a reduced serum level of fibroblast growth factor 19 in patients with biopsy-proven nonalcoholic fatty liver disease
Objectives: We sought to determine whether serum concentrations of fibroblast growth factor 19 (FGF19) - an ileum-derived enterokine which plays a role in the control of glucose and lipid homeostasis - are altered in patients with biopsy-proven nonalcoholic fatty liver disease (NAFLD). Design and methods: Serum levels of FGF19 were measured using enzyme-linked immunosorbent assay in 91 patients with biopsy-proven NAFLD and 74 controls. Results: FGF19 levels were significantly lower in patients with biopsy-proven NAFLD (median: 130 pg/mL) than in controls (median: 210 pg/mL, P<0.001). Serum FGF19 levels were significantly but modestly associated with hepatocyte ballooning scores in univariate analysis (r = -0.25. P<0.05) but not after adjustment for potential confounders (beta = -0.18; t = 1.78, P = 0.08). Conclusions: This pilot study suggests that serum FGF19 levels are decreased in patients with NAFLD but are not independently associated with liver histology findings. (C) 2012 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved
Synthesis, characterization, electrochemistry and VOC sensing properties of novel ball-type dinuclear metallophthalocyanines
New homodinuclear ball-type Cu(II)-Cu(II) 4, Zn(II)-Zn(II) 5, and Co(II)-Co(II) 6 phthalocyanines were synthesized from 4,4'-(9H-fluorene-9-yl-dimethoxy)diphthalonitrile 3, which was obtained by the reaction of 4-nitrophthalonitrile 2 with 9H-fluorene-9,9-dimethanol 1. The compounds were characterized by elemental analysis, UV/vis, IR, H-1 NMR, C-13 NMR and MALDI-TOF mass spectroscopies. Electrochemical and spectroelectrochemical measurements suggested that ball-type phthalocyanine compounds 4-6 form stable mixed-valence species in nonaqueous medium, as a result of the remarkable intramolecular interactions between the two metallophthalocyanine units. Ball-type cobalt phthalocyanine complex, 6 showed high catalytic activity toward dioxygen reduction. Temperature dependence of direct current (dc) conductivity of the films of 4-6 in the range of 295-523 K displayed their semiconductor behavior. Alternating current (ac) conductivity measurements (40 Hz-100 kHz) showed that dominant conduction mechanism for 4-6 can be modeled depending on temperature and frequency. Gas sensing properties of the thin films of 4-6 toward volatile organic compounds (toluene, chloroform, and acetone) at room temperature were good with reversible response. The best sensitivities were obtained with the film of 6 for the vapors of toluene (250 ppm), acetone (150 ppm), and chloroform (1500 ppm) with the values of 1.3 x 10(-1), 1.6 x 10(-2), and 2.1 x 10(-2) ppm(-1), respectively. (C) 2014 Elsevier B.V. All rights reserved
Electrochemical and electrical properties of novel mono and ball-type phthalocyanines
New mononuclear Co(II) phthalocyanine 3 and ball-type homobinuclear Cu(II)-Cu(II) and Zn(II)-Zn(II) phthalocyanines, 4 and 5 respectively, were synthesized using the corresponding metal salts and the 4,4'-(methane-5-methyl-3-(1-methylcyclohexyl)-2,2'-phenoxy)diphthalonitrile ligand 2, which was prepared from the reaction of 4-nitrophthalonitrile with bis[2-hydroxy-5-methyl-3-(1-methylcyclohexyl)phenyl]methane (1). The novel compounds 3-5 have been characterized using their elemental analysis data and UV-Vis, IR, H-1 NMR and MALDI-TOF mass spectra. The redox properties of the complexes were investigated by cyclic voltammetry in a non-aqueous medium. The electrochemical measurements showed that complex 5 forms a mixed-valence reduction species, due to the strong intramolecular interactions between the two phthalocyanine rings. Complex 4 displayed Pc ring-based redox signals with very high peak currents, which were attributed to the adsorption of the complex on the working electrode. Dc and ac electrical properties of films of 3, 4 and 5 were also investigated as a function of temperature (295-523 K) and frequency (40-10(5) Hz). From the dc conductivity measurements, activation energy values of the films were found, being 0.70, 0.66 and 0.68 eV for films of 3, 4 and 5, respectively. From impedance spectroscopy measurements, it was observed that the bulk resistance decreases with increasing temperature, indicating semiconductor properties. (c) 2012 Elsevier Ltd. All rights reserved
Thematic analysis on fatih Emirhan’s povests (Fethulla hazret, hayat, şefigulla agay)
Bu tez çalışmasının amacı Fatih Emirhan’ın “Fethulla Hazret”, “Hayat”, “Şefigulla Agay” uzun hikâyelerinin tematik yönden incelenmesidir. Fatih Emirhan, Tatar edebiyatının önemli yazarlarından biridir. Tatar edebiyatına hikâyeleri ve drama eserleri ile katkıda bulunmuştur. Yazarın eserlerini incelemeden önce “Tatar Türkleri ve Tarihi”, “20. Yüzyıl Tatar Edebiyatı”, “Tatar Edebiyatında Hikâye ve Uzun Hikâye” hakkında bilgiler verilecektir. Devamında “Fatih Emirhan’ın Hayatı, Edebi Kişiliği ve Eserleri” ele alınacaktır. Ayrıca bu bölümde “Fatih Emirhan’ın Eserlerinde Kadınların Özgürlüğü” başlığı altında bilgiler verilecektir. Son bölümde Fatih Emirhan’ın uzun hikâyelerinin özetlerine yer verilecek ve bahsi geçen bu eserlerin tema incelemesi yapılacaktır. Bu çalışmayı diğerlerinden ayırannokta, Fatih Emirhan’ın hayatı ve eserleri üzerinde böyle bir çalışmanın daha önce ayrıntılı yapılmamış olmasıdır. Bu çalışma ile Fatih Emirhan’ın duygu ve düşünceleri dile getirilmeye çalışılacaktır.The aim of this thesis is to examine Fatih Emirhan's “Fethulla Hazret”, “Hayat”, and “Şefigulla Agay” povests **thematically. Fatih Emirhan is one of the important writers of Tatar Literature. He contributed to Tatar Literature with his stories and drama works. Before examining the works of the author, firstly “Tatar Turks and History,” “20th Century Tatar Literature,” and “Story and Povest in Tatar Literature” will be given. Afterwards, “Fatih Emirhan’s Life, Literary Personality, and Works” will be discussed. In addition, in this section, information will be given under the title of “The Freedom of Women in the Works of Fatih Emirhan”. In the last section, summaries of Fatih Emirhan's long stories will be given and thematic analysis of these works will be made. The point that distinguishes this study from others is that such a study on Fatih Emirhan's life and works has not been done in detail before. With this study, Fatih Emirhan's feelings and thoughts will be tried to be expressed
Maintaining mixed neighbourhoods. Fatih plateau: The completed nucleus. A generative strategy for historical Istanbul
The project is the result of a combination of operations performed on the site adjacent to Fatih mosque. It aims to programmatically complete the area’s nucleus to adequately provide for a pluralistic society in conjunction with Fatih mosque that currently dominates the area with its singular religious program. The essential objective is to repair and revitalize the area in the heart of the historical part of the city that apart from the mosque is in a very bad state, by bringing additional public program in, to accommodate for every facet of life in this metropolitan city. The project marries the old fabric below with a new public space above that facilitates virtually all kinds of public program. It consists of three stacked interpretations of universal space. A plinth that negates the hierarchy caused by the topography that does not rely on program to give it its form but rather, inspired by the permanence of monuments, is capable of housing any kind of program for any period of time. On top of the plinth on grade with Fatih mosque the possibility is created for large public programs to take shape as a multitude of expressive buildings that, together with the mosque, form a unity in diversity. The new public space is the interface between, vertically, the existing city and the intensified public program and horizontally, the collective space around the mosque and the new square while at the same time providing all the services for the large public programs on top to allow them to be as autonomous as they can be.Capital Region - IstanbulPublic BuildingArchitecture and The Built Environmen
Green Infrastructure and Flood Resilience in Fatih, Istanbul
This thesis focuses on the challenges Istanbul faces due to extensive urbanisation and global warming. The metropole has become vulnerable to climate change, especially to the increasing threat of floods. As a result of urbanisation and poor city planning, the green spaces have decreased considerably in Istanbul, which reduced stormwater retention considerably. This is concerning, as green infrastructure provide ecosystem services that can serve as flood control. The thesis describes the context of Istanbul’s flood governance, including international, national and metropolitan flood policies and Istanbul’s flood resilience actor-network. In Istanbul’s flood risk management plans, the role that green infrastructure can play in flood control has been neglected. To meet this gap, this study aims to analyse how green infrastructure could enhance Istanbul’s flood resilience. Fatih is one of the oldest districts in Istanbul and is taken as a case study due to its high vulnerability to flash floods. The study presents a case study on Fatih with a spatial approach to monitor flood resilience and ecosystem services through green infrastructures that can foster resilience. A Geographic Information System in combination with a multi-criteria evaluation is used as a tool to identify priority areas for green infrastructure investments. Finally, the effect of three green infrastructure investments is analysed. The research finds that the indicators proposed by Li et al. (2016) are appropriate to use to analyse the priority areas for green infrastructure investment. These indicators reflect a system approach as they include technical, environmental as well as social variables. This is important for the city of Istanbul, as they provide a holistic framework with these indicators. Furthermore, using the flood map provided by ISKI, the flood sensitive areas in Fatih have been identified, and especially the infrastructures surrounding the main boulevard are subject to flooding. Molla Gürani resulted to be the neighbourhood being most flood vulnerable, and therefore the main priority is for green infrastructure development. For this neighbourhood, increased green infrastructure is modelled. The results show a significant reduction in flood vulnerability, which concludes the part green infrastructure have in flood control. The thesis concludes that there is no one-size-fits-all response to enhance flood resilience. Especially since flood resilience is not only based on flood mitigation but rather coping and transforming from floods. Green area investments prove useful to enhance resilience, as these investments provide benefits that can transform the resilience of urban flood management into a more adaptive state due to the nature of the ecosystem services. This research proposes a few recommendations for decision-makers in Istanbul to take into consideration.Industrial Ecolog
Exchange rate increases – Prices follow
Exchange rate increases Prices follow Fatih Ermis After remaining stable for over twenty years, the Lebanese currency started deviating from the fixed 1 USD = 1507 LBP exchange rate in September 2019. The relative price stability of the last two decades also faltered, which comes as no surprise, as Lebanon imports ten times as much as it exports. As will be discussed below, the price increases are lower than the increase in the exchange rate. This is especially the case for domestic goo..
The music tractate presented to the Ottoman Sultan Mehmed II. (Fatih Anonym)
The work also famed as Fatih Anonym upon being dedicated to Mehmed II, sovereign of the period, is one of the most important works in the history of Turkish Music. Fatih Anonym is a work which makes considerable benefits to the construction of basis on the theories of today?s music on the fundamental issues primarily sound systems such as art and tune.Being also a historical record in terms of revealing the level the Turkish music culture has reached in the 15th century, Fatih Anonym has the quality of being a classification and annotation of the works by the major authors in the field of theories of music, as well.While writing the Fatih Anonym, the author has benefitted from the works of the authors like Farabi, İbn-i Sina, Safiyyuddîn Urmevî and Abdulkadir Meragî, previously worked in the field of theories of music. During benefitting from the previous works, the author not only made transference but also added his own thoughts and interpretations. Thus; in his work, he tried to make many issues handled also by the previous authors clear.Fatih Anonym consists of significant information on the issues of the Turkish music which makes the basis on the theories of music primarily tunes and sound systems. In the work, one of the significant sources of Turkish music history, many issues are handled elaborately, such as the numerical rates, tune, ranges, the consistence and inconsistencies of the ranges, kinds, cries, groups, arrangement of the ranges, common sounds in the verses, detection of the 17 pitches on the string, ranges of tunes, ?mücenneb? and ?bakiyye?, progresses and gamut of the modes( of the era) compositions and forms used in compositions, effects of the modes, times for the modes to be performed, transitions in the tunes, tempo, and vocalization.According to the popular opinion, the author of Fatih Anonym is Fethullah Şirvânî. Fatih Anonym, presented to Mehmed II, the sovereign of the period, is not the same as Mecelletü?n fi?l-Mûsika, by Fethullah Şirvânî, although they are similar in terms of style and content.İn terms of many subjects, Fatih Anonym, considerably similar to Şerefiyye by Safiyyuddîn, is a work written after Mecelletü?n fi?l-Mûsika. Many issues not handled in Mecelletü?n fi?l-Mûsika are elaborately dealt in Fatih Anonym. From this point of view, Fatih Anonym is more systematic and extensive in content.Fatih Anonym, gained to the history of the Turkish music through our study, has a quality of being a source needed to be consulted by the researchers on the field of music, and researched extensively.XV. yüzyılda Devrin padişahı II. Mehmed(Fatih)'e ithaf edilmesi ile Fatih Anonimi şeklinde de meşhur olan eser, Türk Mûsikîsi tarihinin en önemli eserlerinden biri olma hüviviyetine sahiptir. Fatih Anonimi, başta ses sistemleri olmak üzere usûl ve makam gibi temel konularda günümüz mûsikî nazariyatının alt yapısının oluşmasında önemli katkılar sağlayan bir eser niteliğindedir.XV. yüzyılda Türk Mûsikî kültürününün almış olduğu seviyeyi deşifre etmesi bakımından da önemli bir tarihi vesika niteliğinde olan Fatih anonimi, aynı zamanda mûsikî nazariyatı sahasında çok önemli eserler kaleme almış olan büyük müelliflerin yazdıkları eserlerin adeta yeniden tasnifi ve şerhi niteliğindedir.Fatih Anonimi'nde müellif, eserini kaleme alırken mûsikî nazariyatı alanında kendisinden önce eser veren Fârâbî, İbn Sînâ, Safiyyuddîn Urmevî ve Abdulkadir Meragî gibi müelliflerin eserlerinden önemli ölçüde yararlanmıştır. Müellif, kendinden öncekilerin eserlerinden yararlanma esnasında sadece nakilcilik yapmamış, aynı zamanda kendi düşünce ve yorumlarını da ilave etmiştir. Böylece müellif, eserinde önceki müelliflerin ele aldıkları mûsikîye ait bir çok konuyu daha anlaşılır bir hale getirmeye çalışmıştır.Fatih Anonimi, Türk Mûsikîsi'nin başta makamlar ve ses sistemleri olmak üzere günümüz mûsikî nazariyatının temellerini oluşturan konularda çok önemli bilgileri içermektedir. Türk Mûsikîsi tarihinin önemli kaynaklarından biri olan eserde sayısal oranlar, nağme(ses ), aralıklar, aralıkların uyumsuzluğu ve uyumu, cinsler, âvâzlar, şû'beler, aralıkların tertibi, dizilerdeki ortak sesler, tel üzerinde 17 perdenin tesbiti, tanînî, mücenneb ve bakiyye aralıkları, makamlar( edvâr)'ın seyir ve dizileri, beste ve beste yapımında kullanılan formlar, makamların tesirleri, makamların icra olunacakları vakitler, nağmelerde intikâl, îkâ (usûl) ve seslendirme gibi bir çok konu ele alınıp ayrıntılı bir şekilde işlenmiştir.Fatih Anonimi'nin müellifi kanaatimizce Fethullah Şirvânî'dir. Devrin padişahı II. Mehmed'e sunulan Fatih Anonimi, Fethullah Şirvânî'ye ait olan Mecelletü'n fi'l-Mûsika adlı esere üslup ve muhteva olarak çok benzese de aynı eser değildir. Her iki eser de kanaatimizce aynı müellifin iki ayrı eseri olup birbirinin muhtasarı ya da farklı redaksiyonlarıdır.Bir çok konu itibariyle Safiyyuddîn'in Şerefiyye adlı eseriyle de hatırı sayılır derecede benzerliği olan Fatih Anonimi, Mecelletü'n fi'l-Mûsika adlı eserden sonra kaleme alınan bir eserdir. Mecelletü'n fi'l-Mûsika'da yer almayan bir çok konuya Fatih Anonimi'nde ayrıntılı olarak yer verilmiştir. Bu yönüyle Fatih Anonimi, muhteva olarak Mecelletü'n fi'l-Mûsika'ya göre daha sistematik ve daha hacimlidir.Üzerinde yaptığımız çalışma ile Türk Mûsikî tarihine kazandırılan Fatih Anonimi, mûsikî sahasında çalışma yürüten araştırmacılar tarafından başvurulması ve üzerinde araştırılması gereken bir kaynak eser özelliği taşımaktadır
Pelaksanaan Pendidikan Non Formal Di Pondok Pesantren Muhammad Al Fatih Sukoharjo Tahun Pelajaran 2019/2020
In the era of increasingly fierce competition for life, demands that every human being be qualified human resources. Education is one of the means to make quality human beings. With education it is hoped that the future will be better. Compulsory education program for school-aged children. However, at the time when there were still many school children who had not received or could not even finish studying for at least 12 years with various reasons. From an Islamic point of view, education is something important that requires its implementation. Pesantren is an alternative to realizing compulsory education programs through non-formal education channels. Based on the background of the problem above, the writer formulated the problem namely "How is the Implementation of Non-Formal Education in Islamic Boarding School Muhammad Al Fatih Sukoharjo? This study aims to study what kind of non-formal education and how to carry out non-formal education in Islamic boarding school Muhammad Al Fatih Sukoharjo. This research uses a field research method that uses descriptive qualitative. Aims to collect data and information from facts that occur. In collecting data using interviews, collection and documentation. While the data analysis method uses Inductive analysis. Based on the results of research conducted by the author, the implementation of Non-Formal Education in Muhammad Al-Fatih Sukoharjo Islamic Boarding School is as follows: (1) The purpose of Non-Formal Education in Muhammad Al-Fatih Islamic Boarding School is to help him follow with skills in various blessings according to his wishes and interests. able to be independent in facing life, (2) Form of Non-Formal Education in Islamic Boarding School Muhammad Al Fatih in the form of learning Diniyah Subjects, General Subjects, and Extra Activities, (3) Non-Formal Education Learning in the form of Mid-Semester Assessment, Final Semester Assessment and Exams National, (4) The main elements in the organization of non-formal education of students, teaching staff, teaching materials and educational environment
Spanne-Guliyev Type Characterization for Fractional Integral Operator and Its Commutators in Generalized Orlicz–Morrey Spaces on Spaces of Homogeneous Type
This paper establishes necessary and sufficient condition for the Spanne-Guliyev type boundedness of the fractional integral operator and its commutators in generalized Orlicz–Morrey spaces over spaces of homogeneous type which satisfy the Q-homogeneous (Ahlfors regular) condition. © 2021, The Author(s), under exclusive license to Springer Nature Switzerland AG
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