169 research outputs found
Henri Temianka Correspondence; (contini)
No full textThis collection contains material pertaining to the life, career, and activities of Henri Temianka, violin virtuoso, conductor, music teacher, and author. Materials include correspondence, concert programs and flyers, music scores, photographs, and books.https://digitalcommons.chapman.edu/temianka_correspondence/1640/thumbnail.jp
Un articolo perduto e una lettera ritrovata. Carteggio Contini-Cecchi-Raimondi
No full textWhen Giuseppe Raimondi’s novel Giuseppe in Italia was published by Mondadori, in April 1949,
the author and his friends Gianfranco Contini and Emilio Cecchi began a period of intense correspondence.
Such correspondence, as presented herein, from May to August 1949, is evidence
of the deep friendship that existed in the relations between the three protagonists of Italian
literary culture and documents a “disagreement” between the great philologist and the author
of Pesci rossi which, in the light of some new letters, confirms again the rigour and ethical-moral
strictness which Contini always stood by, as much in his work as in his life
GIANFRANCO CONTINI ALFREDO SCHIAFFINI CARTEGGIO (1935-1971)
No full textFra tutti i carteggi di Gianfranco Contini (e ne sono stati pubblicati ormai molti: con Carlo Emilio Gadda, Eugenio Montale, Emilio Cecchi, Aldo Capitini, Luigi Russo, Giorgio Pasquali, Giuseppe De Luca, ecc.), quello con Alfredo Schiaffini ha un posto particolare: è il più considerevole per numero di lettere e per durata cronologica (dal 1935 al 1971) con un “addetto ai lavori”, un collega. Quando Contini scrive a Schiaffini per la prima volta, ha ventitré anni. Si è appena laureato in Filologia Romanza all'Università di Pavia, e ha vinto una borsa di studio per perfezionarsi a Parigi, con Joseph Bédier. Schiaffini, quando riceve quella prima lettera da Parigi, il 18 febbraio 1935, ha quarant'anni. È un professore affermato, con cattedra a Genova e incarichi alla Scuola Normale di Pisa. La complicità è immediata. L'affetto, durerà per tutta la vita, e i contatti non si interromperanno mai, fino alla morte di Schiaffini, avvenuta nel 1971.
Succede, nel frattempo, di tutto. Contini diventa la star indiscussa della filologia italiana, venerato e temuto da amici e colleghi, autore di saggi mirabili, che rivoluzionano la disciplina, e punto di riferimento per molti scrittori contemporanei (Montale, Gadda e Pasolini sono solo i più celebri). Nasce, in polemica con Benedetto Croce, e su impulso proprio di Contini, la “critica delle varianti”, che Schiaffini (è tra gli aspetti poco noti emersi da questo carteggio) è fra i primi ad appoggiare e sostenere.
Nel 1935, c'è la guerra. Le biblioteche universitarie non comprano riviste straniere, e Contini procura a Schiaffini, da Parigi, estratti introvabili in Italia, acquistati da Droz. Entrambi i corrispondenti perdono, negli anni della guerra, libri, carte, lettere.
La ricostruzione li vede ancora l'uno accanto all'altro, impegnati, con ruoli diversi, nel programma di ricostruzione della storia letteraria nazionale portato avanti dalla casa editrice Riccardo Ricciardi: Schiaffini è coinvolto da Mattioli fin dal 1949 nella direzione della collana “La letteratura italiana. Storia e testi”, insieme a Pietro Pancrazi, che intende stabilire un 'canone' della letteratura italiana in 75 volumi, da consegnare alla classe dirigente del futuro. Prima ancora che l'incarico sia ufficializzato, ne dà notizia a Contini, e gli affida l'incarico di curare per la collana i due volumi dei Poeti del Duecento, che usciranno nel 1961, e cambieranno il modo di pubblicare i testi delle origini. Poco più tardi, Schiaffini promuove alla Ricciardi una nuova casa editrice, i “Documenti di filologia”: che dirigerà scegliendo di avere al suo fianco, ancora una volta, Contini.
Quarant'anni di storia non solo accademica italiana, come si riflettono nelle lettere di due studiosi che hanno messo le basi della disciplina filologica in Italia.The exchange of letters between Gianfranco Contini and Alfredo Schiaffini is quite peculiar, even if compared with the many ones Contini had with Carlo Emilio Gadda, Eugenio Montale, Emilio Cecchi, Aldo Capitini, Luigi Russo, Giorgio Pasquali, Giuseppe De Luca and others, already published. It is the most considerable for its length and for the incredible number of letters: it lasts from 1935 to 1971 and involves two “colleagues”. Contini addresses his first letter to Schiaffinin on February 18th, 1935: he is only 23 y.o., he has just taken his degree in Romance Philology and obtained a scholarship to specialize with Joseph Bedier in Paris. Schiaffini is a 40 y. o. well known professor at Genova University, who lectures at Pisa Scuola Normale Superiore. Their complicity is immediate; they love each other and won’t interrupt their friendly relation up to Schiaffini’s death in 1971.
Contini is soon going to become the undisputed ‘star’ of Italian Philology, revered and feared by friends and colleagues, author of admirable essays which turn his teaching upside down; the reference point of many contemporary writers (Montale, Gadda and Pasolini are only the best known). Schiaffini supports and backs up at once “critica delle varianti”, born under the impulse of Contini and in dispute with Benedetto Croce: this is one of the less known aspects these letters have drawn the attention on.
In 1935 war is on. University libraries don’t buy foreign reviews and Contini sends Schiaffini otherwise unobtainable off prints he buys at Droz. During the war both Contini and Schiaffini lose books, papers and letters.
Reconstruction sees them again side by side, engaged with different roles in a programme of rebuilding the national literary history planned by Riccardo Ricciardi. Since 1949 Schiaffini has been called by Mattioli, together with Piero Pancrazi, in the executive staff of “La letteratura italiana”. The aim is to establish a “canon” of the Italian Literature in 75 volumes for the ruling class of the future. Schiaffini writes about his new job to his dear friend Contini – even before its officialization, and gives him the task to edit the two volumes on Poeti del Duecento. These will be ready in 1961 and will change the way of publishing the texts of the origins of our lietrature. Soon after Schiaffini promotes “Documenti di filologia”: once again Contini is at his side to share the management.
Forty years of Italian History – not only from an academic point of view, are reflected in the letters of two scholars who laid the foundations of the philological discipline in Italy
The Author replies. Comment on article: Unexpected gallbladder cancer after laparosopi cholecystectomy
No full textHyperplasia vs hypertrophy in tissue regeneration after extensive liver resection
No full textAIM To address to what extent hypertrophy and hyperplasia contribute to liver mass restoration after major tissue loss. METHODS The ability of the liver to regenerate is remarkable on both clinical and biological grounds. Basic mechanisms underlying this process have been intensively investigated. However, it is still debated to what extent hypertrophy and hyperplasia contribute to liver mass restoration after major tissue loss. We addressed this issue using a genetically tagged system. We were able to follow the fate of single transplanted hepatocytes during the regenerative response elicited by 2/3 partial surgical hepatectomy (PH) in rats. Clusters of transplanted cells were 3D reconstructed and their size distribution was evaluated over time after PH. RESULTS Liver size and liver DNA content were largely recovered 10 d post-PH, as expected (e.g. , total DNA/liver/100 g b.w. was 6.37 ± 0.21 before PH and returned to 6.10 ± 0.36 10 d after PH). Data indicated that about 2/3 of the original residual hepatocytes entered S-phase in response to PH. Analysis of cluster size distribution at 24, 48, 96 h and 10 d after PH revealed that about half of the remnant hepatocytes completed at least 2 cell cycles. Average size of hepatocytes increased at 24 h (248.50 μm2 ± 7.82 μm2, P = 0.0015), but returned to control values throughout the regenerative process (up to 10 d post-PH, 197.9 μm2 ± 6.44 μm2, P = 0.11). A sizeable fraction of the remnant hepatocyte population does not participate actively in tissue mass restoration. CONCLUSION Hyperplasia stands as the major mechanism contributing to liver mass restoration after PH, with hypertrophy playing a transient role in the process
Evidence of Amniotic Epithelial Cell Differentiation toward Hepatic Sinusoidal Endothelial Cells
No full textAmniotic epithelial cells (AECs) represent a useful and noncontroversial source for liver-based regenerative medicine, as they can differentiate into hepatocytes upon transplantation into the liver. However, the possibility that AECs can differentiate into other liver cell types, such as hepatic sinusoidal endothelial cells (HSECs), has never been assessed. In order to test this hypothesis, rat- and human-derived AECs (rAECs and hAECs, respectively) were subjected to endothelial cell tube formation assay in vitro. Moreover, to evaluate differentiation in vivo, the retrorsine (RS) model of liver repopulation was used. Pyrrolizidine alkaloids (including RS) are known to target both hepatocytes and endothelial cells, inducing cell enlargement and inhibition of cell cycle progression. rAECs and hAECs were able to form capillary-like structures when cultured under proangiogenic conditions. For in vivo experiments, rAECs were obtained from dipeptidyl peptidase type IV (DPP-IV, CD26) donors and were transplanted into the liver of recipient CD26 negative animals pretreated with RS. rAEC-derived cells were engrafted in between hepatocytes and resembled HSECs as assessed by morphological analysis and the pattern of expression of CD26. Donor-derived CD26+cells coexpressed HSEC markers RECA-1 and SE-1, while they lacked expression of typical hepatocyte markers (i.e., cytochrome P450, hepatocyte nuclear factor 4α). As such, these results provide the first evidence that AECs can respond to proangiogenic signals in vitro and differentiate into HSECs in vivo. Furthermore, they support the conclusion that AECs possesses great plasticity and represents a promising tool in the field of regenerative medicine both in the liver and in other organs
Sui sentieri di «Amoris laetitia». Svolte, traguardi e prospettive
No full textThis article provides food for thought on the radical changes that have affected society and the family in the last fifty years. It explores the reciprocal relationship between family and society, highlighting the profound implications and new cohabitation models that arise from it. The author analyzes the acceleration of changes from the perspective of Jean Francois Lyotard, emphasizing how stability has become transient and how we are confronted with unknown social and cultural configurations. It examines the environment in which individuals face the challenges of surpassing themselves, mastering time, and governing space, considering both physical and virtual spaces. It observes that contemporary humans seem to reject stability, and their relationship with institutions becomes increasingly conflictual. As part of this process, the family is gradually witnessing the erosion of its dimension of certainty. The changes in marriage models over the years are explored, highlighting the decline of religious marriages and the increase in civil marriages and cohabitation. The author emphasizes that change is an ordinary fact in the history of societies and that we need to coexist with it, seeking to guide the cultural path. The impact of these changes on the family and society is analyzed, including the reduction in the number of children and the demographic and economic implications. The article explores contemporary hyper-individualism and the effect of social fragmentation on the construction of identity and relationships. The importance of proposing alternative perspectives and continuing to discuss meaningful narratives to address the concerns and questions of contemporary humans is discussed. Despite the possible drifts, it is stated that the family remains a fundamental and irreplaceable pillar of society, playing an educational and generational nurturing role
Data from: Exploring information flow from posteromedial cortex during visuospatial working memory - a magnetoencephalography study
No full textWork published as: Goddard E, Contini E, Irish M (accepted June 2022) Exploring information flow from posteromedial cortex during visuospatial working memory - a magnetoencephalography study. Journal of Neuroscience, DOI: https://doi.org/10.1523/JNEUROSCI.2129-21.2022. Please cite this paper if you use the data on this project. This project contains a magnetoencephalography (MEG) data set. Participants (n = 12) performed a visuospatial working memory task while we acquired MEG data. For details of what each folder contains, see the project wiki. For details of the stimuli and methodology, see the paper above
Etica della professionalità educante, tra «passioni tristi», empowerment e resistenza
No full textThe article proposes a critical reflection on nowadays cultural globalization, underlying, particularly, the «sad passions» it is connoted with and that characterize young people and adolescents, extinguishing their ability of projecting their future. In order to contrast this tendency, the author suggests a tight commitment by the educational professionals, through competences and meta-competences, plural knowledges and own ethics, in order to promote in the young generations a passionate will of growing trough knowledge, emotions and relationships in a frame of self and social empowerment.El artículo propone una reflexión crítica sobre el contexto cultural, globalizado centrándose en particular en la "tristeza" que los caracterizan y sólo caen pesadamente sobre los jóvenes y adolescentes fuera de sus habilidades de diseño. Para contrarrestar esta tendencia y abierto a la posibilidad de "pasiones alegres" se refiere a los esfuerzos de la profesión de educador, su ética y su capacidad de "resistencia”. En particular, se destaca la importancia de "la sabiduría emocional" que mejora y enriquece la trama entre saber y de sentir y de alentar la fuerza en términos subjetivos y sociales la promoción de la pasión para crecer y participar en las relaciones, pacífica y rica en significado, con algo más.L’essai propose une réflexion critique sur les contextes culturels actuels, globalisés, en les arrêtant en particulier sur les «passions tristes» qui les connotent et qui retombent sur les jeunes et les adolescents, en éteignant leur capacité progettuale. Pour contrarier cette tendance et pour ouvrir à la possibilité de «passions joyeuses», il se fait référence à l’engagement de la professionnalité éducative, à l’empreinte éthique de sa déontologie et capacité de «résistance», aux compétences plurielles et méta-compétences qu’ils doivent la caractériser. En particulier on souligne l’importance d’un «savoir émotionnel» qui valorise et enrichisse l’entrelacement entre le connaître et le sentir et favorise l’empowerment au niveau subjectif et social en recevant la passion à grandir et à s’engager en relations, paisibles et riches de sens, avec l’autre de soi.Il saggio propone una riflessione critica sugli attuali contesti culturali, globalizzati, soffermandosi in particolare sulle «passioni tristi» che li connotano e che ricadono pesantemente proprio sui giovani e gli adolescenti, spegnendo la loro capacità progettuale. Per contrastare questa tendenza e aprire alla possibilità di «passioni gioiose», si fa riferimento all’impegno della professionalità educativa, all’impronta etica della sua deontologia e capacità di «resistenza», alle plurali competenze e metacompetenze che devono caratterizzarla. In particolare si sottolinea l’importanza di una «sapienza emozionale» che valorizzi e arricchisca l’intreccio fra il conoscere e il sentire e favorisca l’empowerment sul piano soggettivo e sociale promuovendo la passione a crescere e a impegnarsi in relazioni, pacifiche e ricche di senso, con l’altro da sé
A NIRS STUDY OF THE HEMODYNAMIC CORRELATES OF COGNITIVEFUNCTIONS
No full textSustained attention (SA) is a function within the construct of attention, defined as the ability to
maintain a consistent level of vigilance and detect unpredictably occurring stimuli over time [1].
Working memory (WM) is a component of memory which encompasses the temporary on-line
maintenance of information and its manipulation [2].
Neuroimaging studies converge to suggest a prominent role of the prefrontal cortex (PFC) in processes
affecting both SA (primarily in the right hemisphere) and WM [2].
Enhanced brain activity associated with cognitive effort induces an increased metabolic consumption
which leads to local hemodynamic changes that modify the optical properties of the cerebral tissue.
Near Infrared Spectroscopy (NIRS) is an optical imaging method that capitalizes on the absorption and
scattering properties of near-infrared light to monitor the hemodynamic changes occurring in response
to functional activation [3]. NIRS has advantages over more common imaging methods including noninvasivity,
portability, better motion tolerance and increased comfort for the participants and is being
widely used to investigate cortical activation related to cognitive processes [3].
One of the most popular WM experimental paradigms is the n-back task, in which participants are
required to monitor a series of stimuli and to respond whenever the currently presented stimulus is the
same as the one presented n trials before [4]. In the 0-back condition the target stimulus is previously
specified and the task is therefore expected to elicit the activation of SA mechanisms to maintain high
vigilance and receptivity levels over time and promptly respond to task-relevant stimuli. In the other
conditions (1-, 2-, ..., n-back) the task requires not only continuous vigilance, but also the storage,
updating and manipulation of newly presented information and is therefore assumed to place great
demands on key processes within WM, inasmuch as the cognitive load increases.
The aims of the present study are to use NIRS to evaluate PFC activation during SA and WM
processes and to investigate the relationships between the cognitive load variation and the cortical
activation patterns
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