84 research outputs found
Extraperitoneal Laparoscopic Versus Transperitoneal Robot-Assisted Laparoscopic Approaches for Extended Pelvic Lymph Node Dissection During Radical Prostatectomy
No full textAksaray, Eren Erdi/0000-0003-1074-1016; Yildiz, Ali/0000-0003-0293-9989; Anil, Hakan/0000-0002-6333-0213Background: We aim to directly compare the feasibility and safety of extended pelvic lymph node dissection (PLND) during transperitoneal robotic-assisted radical prostatectomy (Tp-RARP) and extraperitoneal laparoscopic radical prostatectomy (Ep-LRP). Materials and Methods: We retrospectively identified the prospectively maintained database records of 162 patients diagnosed with prostate cancer (PC) who underwent Ep-LRP or Tp-RARP with extended PLND. Patients with risk of nodal metastases over 5% according to Briganti nomogram received extended PLND. All data analyzed in this study were based on the documentation in our PC database including age, body mass index, Charlson comorbidity index score, preoperative prostate-specific antigen, history of abdominal surgery, biopsy Gleason score, total operation time, postoperative pelvic drainage time, pathological results, lymph node yield (LNY), percentage lymph node involvement (%LNI), and perioperative complications. Patients were followed up for biochemical recurrence in the postoperative period. Results: Eighty-two of the 162 enrolled patients were in group 1 (Ep-LRP+PLND) and 80 were in group 2 (Tp-RARP+PLND). There were no statistically significant differences between the groups regarding preoperative demographics and clinical characteristics. The median LNY was 17 (range 8-27) and 17.5 (range 10-29) in groups 1 and 2, respectively, and no statistically significant difference was found. There was no significant difference between the groups in terms of biochemical recurrence-free survival with mean follow-up of 44.8 months after radical surgery. Conclusion: Our results support the view that extended PLND through the Ep-LRP approach is a feasible and safe procedure without compromising oncological efficacy compared with a similar template attempted during Tp-RARP. Clinical Trial Registration number is 01/21-2.Science Citation Index Expande
Designing train speed and rail temperature measurement system with remote monitoring by internet of things and time based prediction of rail temperature with machine learning/ deep learning
No full textBu tezde belirlenen bir demiryolu hattında ray sıcaklıklarının değişimleri ve seyir halindeki trenlerin hızları nesnelerinin interneti ile uzaktan izlenmiş ve kayıt altına alınan veriler ile makine öğrenmesi/derin öğrenme kullanılarak zamana dayalı ray sıcaklığı tahmini yapan bir sistem geliştirilmiştir. Arka uçlar, ön uç yazılımları ve veri tabanı bulut üzerinde çalışırken, sensör sinyallerini işleyerek ölçümleri gerçekleştiren yazılım mikro kontrolör üzerinde çalıştırılmıştır. Bulut ile mikro kontrolör arasındaki haberleşmeyi sağlayan yazılım ise uç cihaz üzerine kodlanmıştır. Sensörler, sinyal dönüştürücüler, güç kaynağı, mikro kontrolör ve uç cihazından oluşan donanım, demiryolu hattı üzerine konuşlandırılarak saha verileri elde edilmiştir. Bu veriler, internet üzerinden alınan meteoroloji verileri ile birlikte yeni nesil haberleşme protokollerinden vasıtasıyla eş zamanlı olarak bir veri tabanına kaydedilmiş ve bir web sitesinde canlı olarak gösterilmiştir. Bu veriler, belirlenen makine öğrenmesi/derin öğrenme algoritmalarına yüklenerek hedeflenen kriterlere göre algoritma performansları karşılaştırılmış ve uygun algoritma seçilerek web sitesi üzerinden zamana dayalı ray sıcaklığı tahmin edilmiştir.In this thesis, the changes of rail temperatures and the speeds of trains were determined
and monitored remotely with internet of things and an algorithm that predicts the rail
temperature based on time using machine learning / deep learning was developed.
While the back-ends, the front-end software and the database was running on the cloud,
the software that processes sensor signals and performs measurements was run on the
microcontroller. The software that provides communication between the cloud and the micro
controller is coded on the edge device.
The hardware consisting of sensors, signal converters, power supply, micro controller
and edge device was deployed on the railway line and field data was obtained. These data,
together with meteorological data received over the internet, were simultaneously recorded in
a database through new generation communication protocols and displayed live on a website.
These data were loaded into the selected machine learning / deep learning algorithms
and the algorithm performances were compared according to the targeted criteria and the rail
temperature was predicted on the website by selecting the appropriate algorithm
Historiaurrearen, Antzinaroaren eta Erdi Aroaren historia euskaraz. Historia ala fikzioa?
No full textEl objeto del presente artículo es efectuar un breve repaso de la historia e historiografía de la Prehistoria, Antigüedad y Edad Media producidas en euskara. Igualmente, la autora expone brevemente sus reflexiones sobre los problemas y dificultades que supone escribir y trabajar en euskara sobre estos temas.Euskaraz idatzi den Historiaurrearen, Antzinaroaren eta Erdi Aroaren historiari eta historiografiari errepaso labur bat egitea da artikulu honen helburua. Aldi berean, euskaraz arlo hauetan idazteak eta lana egiteak dituen arazo eta zailtasunei buruz, egileak bere gogoetak azaldu ditu laburki.Le but de cet article est d'effectuer une brève révision de l'histoire et de l'historiographie de la Préhistoire, de l'Antiquité et du Moyen Age produites en euskara. De même, l'auteur expose brièvement ses réflexions sur les problèmes et les difficultés que suppose écrire et travailler en euskara sur ces thèmes.The aim of this article is to make a summary about the Prehistory, Antique and Medieval History's historiography written in Basque language. The author gives also her thoughs and experiences about writing and working in Basque about those periods of the History
Effect of different forms of buckwheat addition on the physicochemical and sensory properties of bread
No full textThis study aimed to obtain buckwheat bread by adding whole buckwheat to the white bread formulation in groat and flour form. The addition was made in different proportions (0, 10, 20, and 30%) according to the principle of substitution. Buckwheat addition, as groat, increased the bread's hardness to a great extent. Moisture analysis results indicated that the buckwheat additive can increase the water-holding capacity and may extend the shelf life, especially in flour form. The samples' antioxidant activities and phenolic content significantly increased when the addition was made as flour. All buckwheat-added samples had lower volume values than control samples. Buckwheat addition caused an increase in volatile components such as phenylethanol and benzylalcohol. As a result of sensory analysis, using buckwheat as flour and groat positively affected breadmaking. Considering the samples' nutritional and sensory properties, the combination in which 20% buckwheat flour is added to the white bread formulation is the most appropriate use
Synthesis and Characterization of Hydroxyapatite Powders From Eggshell For Functional Biomedical Application
No full textBulus, Erdi (Arel Author), İsmik, Deniz (Arel Author), Mansuroğlu, Demet Sezgin (Arel Author), Şahin, Yeşim Müge (Arel Author)Apatitic phosphates are considered within the category of bioceramics. HA and its derives are used of in the fields of medicine, orthopedics and dentistry in order to support a grow up of new bone cells. HA structures have a high biocompability and are widely in biomedical applications. On the other hand, synthesis of HA structures necessitates complex technologies (microwave sintering, hydrothermal synthesis etc.) and their production costs high. This study aims the production of nano apatitic structures with great biocompability from a natural material. Simple hotplate method was used to obtain natural, nano scale HA from eggshells. After calcination and sintering processes at different temperatures, the obtained apatitic phosphate powders have been structurally characterized by infrared spectroscopy (FT-IR) and X-ray diffraction (XRD). Morphological investigation has been conducted by FEG-SEM images. Biological investigations have been carried out for the produced nanosized bioceramics and the results reveal that these nanomaterials are promising for tissue engineering purposes
Rock Samphire (Crithmum maritimum L.) as a Functional Food: Awareness, Consumption Habits and Culinary Use
No full textFunctional foods are the name given to food groups that, when consumed, have beneficial effects such as promoting and maintaining metabolic health and preventing diseases, rather than just meeting nutritional needs. Rock samphire (Crithmum maritimum L.), is a plant that grows naturally in the Mediterranean and Aegean regions of Turkey and on the coasts of Cyprus, has been consumed in these regions for many years. The consumption of the rock samphire, which draws attention with its high iodine and bioactive component content, has been limited to the regions where it grows. In this study, the local consumption habits, recipes of the rock samphire plant and the awareness of its functional properties were determined. In the study, six different recipes were obtained from the local people. Traditional products prepared according to the recipes were photographed by the authors. In addition, twenty local people were interviewed and it was determined that consumers were informed about the functional properties of the rock samphire and that these properties motivated consumers to consume the plant. As a result of the study, it was concluded that the integration of locally-consumed rock samphire into the daily diets by introducing them into non-regional cuisines would contribute positively to the general public health and the economy of the region
Unveiling the Link Between Low Handgrip Strength and Diabetic Foot Disease in Non-Geriatric Type 2 Diabetes Patients
No full textThermochemistry of N-heterocyclic carbenes with 5-, 4-, 3-, and 2-membered rings
No full text#nofulltext# Bleda, Erdi A. (Arel Author)N-heterocyclic carbenes (NHCs) based on imidazole-2-ylidene (1) or the saturated imidazolidine-2-ylidene (2) scaffolds are long-lived singlet carbenes. Both benefit from inductive stabilization of the sigma lone pair on carbon by neighboring N atoms and delocalization of the N pi lone pairs into the nominally vacant p-pi atomic orbital at the carbene carbon. With thermochemical schemes G4 and CBS-QB3, we estimate the relative thermodynamic stabilization of smaller ring carbenes and acyclic species which may share the keys to NHC stability. These include four-membered ring systems incorporating the carbene center, two trivalent N centers, and either a boron or a phosphorus atom to complete the ring. Amino-substituted cyclopropenylidenes have been reported but three-membered rings containing the carbene center and two N atoms are not known. Our calculations suggest that amino-substituted cyclopropenylidenes are comparable in stability to the four-membered NHCs but that diazacyclopropanylidenes would be substantially less effectively stabilized. Concluding the series are acyclic carbenes with and without neighboring N atoms and a series of “two-membered ring” azapropadienenylidene cations of form :C[DOUBLE BOND]N[DOUBLE BOND]W with W = an electron-withdrawing agent. We have studied W = NO2, CH2(+), CF2(+), and (CN)2C(+). Although these systems display a degree of stabilization and carbene-like electronic structure, the stability of the NHCs is unsurpassed
High-order harmonic generation from Rydberg states at fixed Keldysh parameter
No full textBleda, Erdi A. (Arel Author)Because the commonly adopted viewpoint that the Keldysh parameter ? determines the dynamical regime in strong field physics has long been demonstrated to be misleading, one can ask what happens as relevant physical parameters, such as laser intensity and frequency, are varied while ? is kept fixed. We present results from our one- and fully three-dimensional quantum simulations of high-order harmonic generation (HHG) from various bound states of hydrogen with n up to 40, where the laser intensities and the frequencies are scaled from those for n = 1 in order to maintain a fixed Keldysh parameter ?< 1 for all n. We find that as we increase n while keeping ? fixed, the position of the cut-off scales in well defined manner. Moreover, a secondary plateau forms with a new cut-off, splitting the HHG plateau into two regions. First of these sub-plateaus is composed of lower harmonics, and has a higher yield than the second one. The latter extends up to the semiclassical Ip + 3.17Up cut-off. We find that this structure is universal, and the HHG spectra look the same for all n & 10 when plotted as a function of the scaled harmonic order. We investigate the n-, l- and momentum distributions to elucidate the physical mechanism leading to this universal structure
Phase-dependent interference fringes in the wavelenght scaling of harmonic efficiency
No full textBleda, Erdi A. (Arel Author)We describe phase-dependent wavelength scaling of high-order harmonic generation efficiency driven by ultra-short laser fields in the mid-infrared. We employ both numerical solution of the time-dependent Schr¨odinger equation and the Strong Field Approximation to analyze the fine-scale oscillations in the harmonic yield in the context of channel-closing effects. We show, by varying the carrier-envelope phase, that the amplitude of these oscillations depend strongly on the rescattering electron trajectory counts. Furthermore, the peak positions of the oscillations vary significantly as a function of the carrier-envelope phase. Owing to its significant practical applications, we also investigate the wavelength dependence of harmonic yield in the single-cycle limit, finding that scaling near the cut-off region departs from the commonly observed ? -x behavior. For a fixed spectral range, we identify a surprisingly smooth behavior of x in ? -x as a function of the ionization potential in the single-cycle limit, which shows suppression of the oscillations in the overall wavelength-scaling. Moreover, we observe that the harmonic efficiency scales as ? -x with x = 5.2, independent from the target atom, and in reasonable agreement with the semi-classical x = 5 scaling
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