1,550 research outputs found
Analisis Karakteristik Pasien Jatuh Di RS. RK. Charitas Palembang
No full textBackground: Patient falls are a challenge for the entire hospital because of the
complex causes, the high incidence, and the magnitude of the risk posed. Analysis
of the characteristics of patient fall is the basis for an illustration of the risks of
falling patients and a preliminary step for the hospital to make improvements and
changes to follow-up prevention plans and the risk of injury from falling.
Aim:To know the characteristics of patient falls in The RK. Charitas Hospital
Palembang.
Method: This study used descriptive method with retrospective design performed
on 133 samples of patient safety incident report of patient falls in inpatient for
analysis of output characteristics, and 102 samples of patient falls medical record
for input characteristic analysis.
Results: The results of this study showed that the highest falls rate was 0.56 per
1000 bed days occurred on 2015, while the highest injury related fall rate was
0.24 per 1000 bed days occurred on 2016. Minor injury were the most injuries that
occurred in patients fall with injuries 90%. Patients with a high fall risk score are
most faller 69.6%, commonly happened in infants (0-5 years) and the elderly (45-
65 years) were 23.5%, male gender was 57.8%, the category of diagnosis was
more than one diagnosis 41.2%, but most physical conditions in other categories
(outside the category criterias) 49%. Patients fell received more than 3 drugs
(polifarmasi) 59.8%. Most of the falls ocurred during the night shift (20: 31-06:
59) 28.4%. Activity related with elimination needs 55.9% are the higest on
patients fall. The environtment conditions on patients fall were unknown 50%.
Patients fall often occur under family supervision 66.7%.
Conclusion: Further efforts to prevent fall in patients in the RK. Charitas Hospital
Palembang need to be improved
Generalized TASE-RK methods for stiff problems
No full textA family of Time-Accurate and Stable Explicit (TASE) methods for the numerical integration of Initial Value Problems in stiff Ordinary Differential Equations (ODEs) y'(t) = f (t, y) was recently introduced in [1]. The main idea was to make local extrapolation of a stabilized Euler method. More recently, in [3] a similar approach by considering the stabilization of arbitrary explicit Runge-Kutta methods (TASE-RK) was analyzed. In this case the explicit Runge-Kutta method integrates a transformed ODE obtained by multiplying the vector field f (t, y) by a certain operator which approximates the identity mapping up to a given order p. The main inconvenience of both approaches is that to reach order p the solution of p2 linear systems plus the evaluation of p derivatives are required per integration step.In order to substantially reduce the computational costs of the former approaches in the linear system solution, but maintaining the good accuracy and stability properties, a new family of TASE-RK methods which allow to introduce a few more free parameters are considered. The formulation of the methods was conceived to be implemented not only in sequential mode but it admits parallelism in a straightforward way. Furthermore, since these methods are linearly implicit, connections to the class of W-methods [19] are properly established. The order conditions for the new class of methods are widely studied by using the rooted tree theory. For p = 3, 4, new methods with p sequential stages and order p are derived and compared on semidiscrete 1D and 2D Partial Differential Equations (PDEs) to those in [1,3] and other standard Rosenbrock and W-methods in the literature.(c) 2023 The Author(s). Published by Elsevier B.V. on behalf of IMACS. This is an open access article under the CC BY-NC-ND license (http:// creativecommons .org /licenses /by-nc -nd /4 .0/)
Mechanistic studies on rhodopsin kinase : a farnesylated protein
No full textAt least 3 proteins involved in visual signalling are isoprenylated. In this thesis the role of the farnesyl group in the interaction of rhodopsin kinase with Rho* was investigated. An efficient method was devised for the synthesis of farnesyl peptides whose sequences corresponded to 12 to 24 C-terminal amino acids of bovine rhodopsin kinase and the γ-subunit of transduction. The farnesyl peptides, but not their non-farnesyl counterparts, inhibited the phosphorylation of Rho* by rhodopsin kinase with IC50 values of 500 μM for the farnesyl derivative of residues 544 to 558 of rhodopsin kinase (Far-15-mer RK) and 800 μM for the farnesyl derivative of residues 60 to 71 of the γ-subunit of transducin (Far-12-mer Tγ). The mechanism of this inhibition was studied by spectroscopic methods since the spectral intermediate metarhodopsin II is believed to be equivalent to Rho*. Using ovine rod outer segment membranes a half-life for the decay of metarhodopsin II (λmax 389 nm) into its product, metarhodopsin III (λmax 463 nm), of 3.2 minutes (20oC pH 8.0) was regularly obtained. The farnesyl peptides increased this value; Far-15-mer RK to 5.21 minutes and Far-21-mer Tγ to 8.02 minutes, with non-farnesyl peptides having no effect. Therefore, the farnesyl group of the farnesyl peptides is required for stabilisation of metarhodopsin II, as measured by its half-life, as it is for inhibition of Rho* phosphorylation by rhodopsin kinase. The specificity of these interactions was investigated using a range of detergents (500 μM final concentration). Although detergents had a drastic effect on the stability of metarhodopsin II, these effects were found to be non-specific and were attributed to a general membrane disruption effect. In addition, generally no significant inhibition by detergents of the phosphorylation of Rho* by rhodopsin kinase was observed. These results suggest that farnesyl peptides inhibit the phosphorylation of Rho* by rhodopsin kinase by binding to Rho*.</p
The multi-level nature and extent of secondary victimization among adult, female rape victims at the RK Khan Thutuzela Care Center.
No full textMasters Degree. University of KwaZulu-Natal, Durban.Rape is a traumatic and life-threatening experience, and one that cannot be easily forgotten by the survivor. It leaves the rape survivor full of fear, doubt, and anger. The resulting fear and anger also ripple through to family members, friends, and the community. Women's and girls' mental and physical health have been shown to be negatively impacted by gender-based violence, which is widely acknowledged around the world.
This research study aimed to encapsulate the nature and extent of secondary victimization amongst adult, female rape victims at the RK Khan Thutuzela Care centre, and their respective social systems using Bronfenbrenner’s Systems theory as a basis. A qualitative methodological approach was applied, and data was collected in a descriptive manner through semi-structured question-interviews.
The study found that the participants' knowledge and comprehension of the concept of secondary victimization were limited. The data also demonstrated that while there were a variety of impacts felt by all participants, all the participant’s do experience secondary victimization and its effects, on various levels over a prolonged period of time. There is currently no structure or procedure in place to help victims cope with all these extended aftereffects so the researcher proposes the need for a multi-faceted approach toward rape victim empowerment
The morphological effects of sediment diversions the Lower Mississippi River
No full textThe wetlands in the Mississippi delta (USA) are drastically subsiding and eroding. Many projects and researches are ongoing to determine how this “drowning effect” of the delta can be stopped. One of the solutions that could be feasible is implementing sediment diversions in the levees of the Lower Mississippi River in order to divert sediment into the delta. This thesis addresses the morphological effects of river diversions on the Lower Mississippi River. The main objective is to analyze and optimize trade-offs between delta building and river navigability. For this purpose a 2DH numerical model with Delf3D has been created; the model simulates the hydro- and morphodynamic behavior. The river reach which has been studied is the final 110 km of the river from Point a la Hache at River Kilometer 78 (RK 78) down to the mouth of the river (RK -30), below Head of Passes. The hydrodynamic model has been calibrated and verified with flow and stage data from daily observations on the river. With the available sediment data a calibration has been carried out of the morphological behavior in the river. The model has been used to simulate several scenarios to get insight in the problems in the delta. From analysis of the model results the river bed in the study area can be divided into three categories. Upstream of RK 4 the bed is subject to erosion, around RK 4 the bed is practically in equilibrium and downstream of RK 4 the bed is subject to sedimentation. The reach downstream of RK 4 is the dredging reach; after analyzing the long-term simulation of 20 years it is not expected that the dredging quantities will decrease in the future. Closing off West Bay diversion has a positive effect on the dredging quantities. The best diversion site for this study area is found in the inner bend of the river upstream of Empire (RK 47) at RK 53. This site is most efficient and diverts the largest quantities of sand through the diversion.Hydraulic EngineeringCivil Engineering and Geoscience
The Dunston Manuscript
No full textVariously titled 80 Slides and a Memory, Fit for a King and others this is the definitive performed version as an invited reading in 2001 to the Urban Design Group. It describes in blank verse the early stages of the Gateshead Garden Festival illustrated with slide
Designing a prosthesis to simulate the elastic properties of skin
No full textThe materials which are currently used to make maxillofacial prostheses are far from ideal and require considerable improvement with respect to their ability to mimic the properties of skin. To this aim, a novel three-layered maxillofacial prosthesis has been designed consisting of a silicone rubber base layer, an inner gel layer and an outer polymeric coating (to simulate the elastic properties of skin). The aim of the work in this study was to develop the inner silicone gel layer which displays similar properties to facial skin. Through the use of unique linear extensometry testing, in vivo measurements for the Area under the Curve (AUC), Hysteresis (viscoelastic behaviour), Fmax (maximum force), F30 and F60 (force after 30 and 60 seconds) were obtained from the facial skin of 15 volunteers. The results were used as a basis for developing silicone gel formulations for the inner layer, to closely resemble those of facial skin. Gels were made by the addition of both low and high molecular weight unreactive silicone fluids and were further tested for compression, water absorption and dehydration. Testing showed that a gel has been produced that closely simulates the elastic properties of skin when bonded to a base silicone rubber layer. Further testing will need to deduce whether these properties will be affected by the addition of the outer polymeric layer
Comparison of four composite deprivation indices and two census variables in predicting oral disease in 12-year-old children in Wales
No full textAssociating Gender with Neighbourhood Deprivation in Lagos State, Nigeria
No full textAJOL has removed this paper from the website after it was found to be published in another academic publication. AJOL has requestd that both journal editorial boards investigate this matter further with the author
- …
