382 research outputs found
Study of association between oncogenic polyomaviruses and ocular melanoma, and p53 gene analysis of the tumor in relation to the radio-therapy resistance.
No full textThe aim of this study is to verify the putative association between oncogenic polyomaviruses (1), and ocular melanoma (OM). To this purpose two cohorts composed of ocular melanoma affected patients and healthy blood donors, employed as a control group, are enrolled in this investigation. The two cohorts have the same median age. The association of polyomaviruses with OM is investigated by searching, in serum samples, specific antibodies against viral capsid proteins. Serum antibodies against polyomaviruses are analyzed by an indirect ELISA with synthetic peptides which mimic specific capsid polypeptide antigens (2). In the first step of our investigation indirect ELISAs employing synthetic peptides was set up and standardized for the detection of specific serum antibodies against polyomaviruses SV40, BKV and JCV. ELISA data showing the prevalence of anti-polyomavirus antibodies in serum samples from OM patients, compared to that detected in samples from healthy subjects will be presented.
It has been shown that p53 gene mutations affect more than 50% of human tumors. p53 gene mutations, in exons 5-8, are responsible of absence of apoptosis, and resistance to chemo- and radio-therapies. The aims of our study is to verify whether ocular melanomas, which are resistant to radio-therapy (20%), carry specific p53 mutations in comparison to the p53 profile of radio-therapy sensitive tumors.
1. Martini F, Corallini A, Balatti V, Sabbioni S, Pancaldi C, Tognon M. Simian virus 40 in humans. Infect. Agent and Cancer. 2007;2:1-13.
2. Corallini A, Mazzoni E, Taronna A, Manfrini M, Carandina G, Guerra G, Guaschino R, Vaniglia F, Magnani C, Casali F, Dolcetti R, Palmonari C, Rezza G, Martini F, Barbanti-Brodano G, Tognon MG. Specific antibodies reacting with simian virus 40 capsid protein mimotopes in serum samples from healthy blood donors. Hum. Immunol. 2012;73:502-510
Conservation tillage and N fertilization affect soil aggregate distribution, carbon storage and enzymatic activities
No full textConservation agriculture is globally recommended for increasing carbon (C) stock in soil and reducing greenhouse gases emissions by modifying soil physical, chemical and biological processes. In the present study, soil aggregate fractions, soil organic C (SOC) and soil enzymatic activities in bulk soil and microaggregates within macroaggregates (mM) were measured in a long-term field experiment comparing conventional tillage (CT) and minimum tillage (MT) and N fertilizer to the rotation bread wheat (Triticum aestivum L.) – soybean (Glicine max L. Merr.). Under MT, a higher proportion of free microaggregates and a lower proportion of silt and clay was recorded compared to conventional tillage, suggesting a greater potential to form macroaggregates, despite their proportion was not modified by tillage. However, when macroaggregates were further fractionated, MT resulted in higher proportion of microaggregates. In bulk soil and in mM, all soil enzymatic activities were higher under MT than CT. Conversely, SOC in bulk soil was not modified by tillage, but was higher under MT in mM. These results demonstrate the crucial role of mM for C sequestration under reduced tillage. Thus, this fraction is proposed as an effective diagnostic tool to assess variations in carbon storage induced by agricultural practices
Clinical anophthalmos in a family
No full textMonolateral or bilateral anophthalmos recurring in the absence of other associated defects in six members of a family is reported. The malformation appears to be inherited as a dominant (autosomal or X‐linked) trait with incomplete penetrance. Implications for genetic counselling are briefly discussed. Copyright © 1987, Wiley Blackwell. All rights reserve
“VENERE PRIVATA” DA SCERBANENCO A BACILIERI: LINGUA, STILE E RETORICA DALLA LETTERATURA AL FUMETTO
No full textIl romanzo Venere privata di Giorgio Scerbanenco (1966) è tra i capostipiti del giallo italiano contemporaneo e introduce il personaggio Duca Lamberti, medico radiato dall’ordine per aver praticato l’eutanasia su una paziente e diventato, una volta scontata la pena, consulente della polizia milanese. La narrazione, la lingua e lo stile dell’autore, già studiati da diversi interventi specialistici, sono ora oggetto dell’adattamento a fumetti di Paolo Bacilieri, apparso a puntate sulla rivista Linus a partire dall’agosto 2021. La pubblicazione dovrebbe concludersi in rivista entro l’anno, ed è prevista per l’autunno 2022 l’edizione integrale in volume per Oblomov. Il presente studio affronta le prime sei puntate dell’adattamento, ne studia la lingua e lo stile in relazione al testo originale, la raffigurazione di ambienti, personaggi e situazioni in relazione agli elementi diegetici del romanzo e a modelli esterni usati da Bacilieri, infine la configurazione degli elementi iconici e verbali nelle tavole in prospettiva retorica. Ciò consente di comprendere non solo il processo e il concetto di adattamento attuati dall’autore, ma anche la lettura e l’interpretazione che questi ha fatto del racconto, della lingua e dello stile del testo originario.
Venere privata from Scerbanenco and Bacilieri: language, style and rhetoric from literature to comics
Giorgio Scerbanenco’s novel Venere privata (1966) is among the progenitors of the contemporary Italian detective story and introduces the character Duca Lamberti, a doctor disbarred for practicing euthanasia on a patient and becoming, once he has served his sentence, a consultant to the Milanese police. The author’s narrative, language and style, which have already been studied by several specialist papers, are now the subject of Paolo Bacilieri\u27s comic book adaptation, appearing serialized in Linus magazine starting in August 2021. The publication is expected to be completed in the magazine within the year, and a full volume edition for Oblomov is planned for Fall 2022. The present study deals with the first six installments of the adaptation, studying the language and style in relation to the original text, the depiction of the environments, characters and situations in relation to the diegetic elements of the novel and external models used by Bacilieri, and finally the configuration of the iconic and verbal elements in the tables in rhetorical perspective. This allows us to understand not only the process and concept of adaptation implemented by the author, but also his reading and interpretation of the story, language and style of the original text
Is unicondylar osteoarticular allograft still a viable option for reconstructions around the knee?
No full textBackground: Unicondylar osteoarticular allografts (UOAs) represent a possible technique for reconstructing massive bone defects around the knee when only one condyle is affected. The aim of this retrospective study is to evaluate the outcome of UOAs and describe the possible salvage procedures in case of graft failure. Methods: Twenty-five deep-frozen UOAs were implanted at Rizzoli Orthopedic Institute (Bologna, Italy). Twenty-two followed bone tumor resection, two cases were post-traumatic defects and one case followed UOA failure.Mean age at surgery was 33. years (range: 15 to 63). Eighteen UOAs were in distal femur, seven in proximal tibia. Results: Three patients died (only one because of the tumor). One UOA was removed for chondrosarcoma relapse and one for allograft fracture. Mean overall survival with UOA failure as a primary endpoint was 129. months (range 12 to 302), with differences in the femur (85%) and in the tibia (40%) at 150. months. Six UOAs had to be converted into knee prostheses due to osteoarthritis after a mean follow-up of 146. months. No complications were recorded in UOAs converted into knee prostheses after a mean three year follow-up. Fourteen patients with UOAs still in place at the last follow-up (mean 123. months) were radiologically and functionally evaluated: no correlation was found between function and the degree of osteoarthritis. Conclusions: In selected cases, UOAs offer good clinical results and postpone the need for knee prosthesis. Despite short-term encouraging results, longer-term follow-up is needed in order to evaluate the outcome of knee prosthesis after UOA
Idiopathic central retinal vein occlusion in a thrombophilic patient with the heterozygous 20210 G/A prothrombin genotype
No full textPURPOSE: To report the occurrence of monolateral central retinal vein occlusion in a patient with heterozygous 20210 G/A prothrombin genotype, known to be associated with high thrombophilic risk.
METHODS: A monolateral central retinal vein occlusion was diagnosed in a 71-year-old woman, who had suffered from a deep vein thrombosis in her left leg at the age of 36 years. Mutations of the genes involved in the coagulation process were investigated by DNA polymerase chain reaction.
RESULT: DNA analysis showed the patient to be heterozygous for the prothrombin 20210 G/A genetic variation.
CONCLUSION: The 20210 G/A prothrombin gene mutation may be associated with central retinal vein occlusion
Datasets of the article "From Classification to Quantification in Tweet Sentiment Analysis"
No full textDatasets used for the following SNAM paper:
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Title: From Classification to Quantification in Tweet Sentiment Analysis
Authors: Wei Gao and Fabrizio Sebastiani
Organization: Qatar Computing Research Institute, Hamad Bin Khalifa University, Doha, Qatar
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[Content]
* SemEval2013, SemEval2014, SemEval2015 datasets:
- semeval.train.feature.txt: Training set for learning sentiment models at development stage
- semeval.dev.feature.txt: Held-out set for tuning parameters
- semeval.train+dev.feature.txt: Training set for learning the final sentiment model
- semeval13.test.feature.txt: SemEval2013 test set
- semeval14.test.feature.txt: SemEval2014 test set
- semeval15.test.feature.txt: SemEval2015 test set
* Other datasets: semeval2016, sanders, sst, omd, hcr, gasp, wa, wb
- X.train.feature.txt: Training set for learning sentiment models at development stage
- X.dev.feature.txt: Held-out set for tuning parameters
- X.train+dev.feature.txt: Training set for learning the final sentiment model
- X.test.feature.txt (or X.dev-test.feature.txt for semeval2016 only): Test set
where X is one of semeval2016, sanders, sst, omd, hcr and gasp.
* Training files are saved in ./data/train directory, and held-out and test files are in ./data/test directory
For more details, please refer to the paper.
[Citation]
You can cite the following paper when referring to the dataset:
@article{gao2016classification,
title={From classification to quantification in tweet sentiment analysis},
author={Gao, Wei and Sebastiani, Fabrizio},
journal={Social Network Analysis and Mining},
volume={6},
number={1},
pages={19},
year={2016},
publisher={Springer}
L'approccio giornalistico alla violenza maschile contro le donne in Italia. I casi studentesse-Camuffo/Costa, Pomarelli-Sebastiani, Bagnai-Genovese
No full textThis article presents the results of a quali-quantitative research conducted on the journalistic approach to male violence against women in Italy, specifically the rape of two girls by Pietro Costa and Marco Camuffo, the feminicide of Elisa Pomarelli by Massimo Sebastiani and the rape of Aurelia Bagnai by Alberto Genovese. The objective was to analyze the newspapers portrayal of the three events, but also how they responded to criticism, on social media or by other media outlets, regarding a narrative perceived as biased against the victims. The theoretical frameworks of the psycho-individualistic paradigm and the feminist/constructivist paradigm were used to analyze these cases
: Two Datasets for the Computational Authorship Analysis of Medieval Latin Texts
No full textWe present and make available MedLatinEpi and MedLatinLit, two datasets of medieval Latin texts to be used in research
on computational authorship analysis. MedLatinEpi and MedLatinLit consist of 294 and 30 curated texts, respectively,
labelled by author; MedLatinEpi texts are of epistolary nature, while MedLatinLit texts consist of literary comments and
treatises about various subjects. As such, these two datasets lend themselves to supporting research in authorship analysis
tasks, such as authorship attribution, authorship verification, or same-author verification. Along with the datasets, we provide
experimental results, obtained on these datasets, for the authorship verification task, i.e., the task of predicting whether a
text of unknown authorship was written by a candidate author. We also make available the source code of the authorship
verification system we have used, thus allowing our experiments to be reproduced, and to be used as baselines, by other
researchers. We also describe the application of the above authorship verification system, using these datasets as training
data, for investigating the authorship of two medieval epistles whose authorship has been disputed by scholars.
on computational authorship analysis. MedLatinEpi and MedLatinLit consist of 294 and 30 curated texts, respectively,
labelled by author; MedLatinEpi texts are of epistolary nature, while MedLatinLit texts consist of literary comments and
treatises about various subjects. As such, these two datasets lend themselves to supporting research in authorship analysis
tasks, such as authorship attribution, authorship verification, or same-author verification. Along with the datasets, we provide
experimental results, obtained on these datasets, for the authorship verification task, i.e., the task of predicting whether a
text of unknown authorship was written by a candidate author. We also make available the source code of the authorship
verification system we have used, thus allowing our experiments to be reproduced, and to be used as baselines, by other
researchers. We also describe the application of the above authorship verification system, using these datasets as training
data, for investigating the authorship of two medieval epistles whose authorship has been disputed by scholars
SAT vs. Translation Based decision procedures for modal logics: a comparative evaluation
No full textThis paper follows on previous papers which present and evaluate various decision procedures for modal logics. It confirms previous experimental results in showing that SAT based decision procedures, i.e., the procedures built on top of decision procedures for propositional satisfiability, are more efficient than tableau based decision procedures. It also confirms previous evidence of an easy-hard-easy pattern in the satisfiability curve for modal K. Finally, it provides further experimental results, suggesting that SAT based decision procedures are also more efficient than the decision procedures based on translation methods. These results contradict some of the claims presented in previous papers by other author
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