317 research outputs found
Open Data: Alpha-band activity reveals spontaneous representations of spatial position in visual working memory
Data and code for the paper: Foster, Bsales, Jaffe, and Awh (2017). Alpha-band activity reveals spontaneous representations of spatial position in visual working memory. Current Biology
Open Data 2017: Clear evidence for item limits in visual working memory.
Data associated with the publication: Adam, Vogel, and Awh (2017) Clear evidence for item limits in visual working memory. Cognitive Psychology
Open Data for "Memory compression" effects in visual working memory are contingent on explicit long-term memory
This data is associated with the publication: Ngiam, Brissenden and Awh (2019). "Memory compression" effects in visual working memory are contingent on explicit long-term memory. Journal of Experimental Psychology: Genera
Open data 2019: Perturbing neural representations of working memory with task-irrelevant interruption
Data associated with the publication: Hakim, Feldmann-Wüstefeld, Awh & Vogel (2019) Perturbing neural representations of working memory with task-irrelevant interruptions. Journal of Cognitive Neuroscience
Open data 2019: Perturbing neural representations of working memory with task-irrelevant interruption
Data associated with the publication: Hakim, Feldmann-Wüstefeld, Awh & Vogel (2019) Perturbing neural representations of working memory with task-irrelevant interruptions. Journal of Cognitive Neuroscience
Open Data 2021: Controlling the Flow of Distracting Information in Working Memory
Data and scripts associated with the publication: Hakim, N., Feldmann-Wüstefeld, T., Awh, E., & Vogel, E. K. (2021). Controlling the Flow of Distracting Information in Working Memory. Cerebral Cortex
Open Data 2021: Controlling the Flow of Distracting Information in Working Memory
Data and scripts associated with the publication: Hakim, N., Feldmann-Wüstefeld, T., Awh, E., & Vogel, E. K. (2021). Controlling the Flow of Distracting Information in Working Memory. Cerebral Cortex
Open Data 2021: Controlling the Flow of Distracting Information in Working Memory
Data and scripts associated with the publication: Hakim, N., Feldmann-Wüstefeld, T., Awh, E., & Vogel, E. K. (2021). Controlling the Flow of Distracting Information in Working Memory. Cerebral Cortex
LIM-homeodomain transcription factor Awh is a key component activating all three fibroin genes, fibH, fibL and fhx, in the silk gland of the silkworm, Bombyx mori
In the silkworm Bombyx mori, three fibroin genes, fibroin-heavy-chain (fibH), fibroin-light-chain (fibL) and fibrohexamerin (fhx), are coexpressed only in the posterior silk gland (PSG) cells, while the sericin genes encoding silk glue proteins are expressed in the middle silk gland (MSG) cells. Silk gland factor-2 (SGF-2) is a PSG-specific activator complex of fibH, composed of a LIM-homeodomain protein, Awh, and its cofactors, Ldb and Lcaf. We investigated whether SGF-2 can activate other fibroin genes using transgenic silkworms. The genes for Ldb and Lcaf were expressed ubiquitously in various tissues, while the gene for Awh was expressed strictly specific in PSG of the wild type silkworms. Misexpression of Awh in transgenic silkworms induced ectopic expression of fibL and fhx as well as fibH in MSG. Coincidently with the induction of fibL and fhx by Awh, binding of SGF-2 to the promoter of fibL and fhx was detected in vitro, and SGF-2 binds directly to the fhx core promoter. Ectopic expression of the fibroin genes was observed at high levels in the middle part of MSG. Moreover, fibL and fhx were induced in the anterior silk gland (ASG) of the transgenic silkworms, but fibH was not. These results indicate that Awh is a key activator of all three fibroin genes, and the activity is probably regulated in conjunction with additional factors
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