100,581 research outputs found
DOUBLE RESONANCE VIBRATIONAL SPECTROSCOPY FOR THE INVESTIGATION OF STRUCTURES AND DYNAMICS OF MOLECULAR CLUSTERS
No full textT. Ebata, A. Fujii and N. Mikami, Int. Rev. Phys. Chem. 17, 331 (1998) R. Yamamoto, S. Ishikawa, T. Ebata, and N. Mikami, J. Raman Spectrosc. 31,295(2000) Y. Matsumoto, T. Ebata, and N. Mikami, Chem. Phys. Lett. In pressAuthor Institution: Graduate School of Science, Tohoku UniversityDouble resonance vibrational spectroscopy is becoming a powerful spectroscopic method for the determination of molecular clusters formed in supersonic free jets. By using an advantage of high sensitivity and selectivity of electronic spectroscopy, we can measure IR and Raman spectra of the size- and isomer-selected cluster. Several spectroscopic methods will be ; IR-UV and stimulated Raman-UV double resonance spectroscopies for the clusters the electronic ground state, and UV-IR double resonance spectroscopy for the electronically excited clusters. We first demonstrate their application to the clusters in the electronically ground state, such as van der Waals clusters of and hydrogen-bonded clusters of 7-. The observed spectra are compared with those obtained by ab initio calculations, and their structures, dynamics and reactivities are discussed. We then change the subject to the OH and/or NH stretching vibrations of electronic excited molecules and their hydrogen-bonded clusters to see how the electronic excitation affects the strength of the hydrogen-bonding
ELECTRONIC SPECTRA OF CALIX[n]ARENE AND ITS VAN DER WAALS CLUSTERS IN SUPERSONIC JETS
No full textT. Ebata, Y. Hodono, T. Ito and Y. Inokuchi, J. Chem. Phys. 126, 141101 (2007).Author Institution: Department of Chemistry, Graduate School of Science, Hiroshima University, Higashi-Hiroshima, 739-8526, JapanElectronic structure and encapsulation of neutral guest molecules have been studied for Calix[4]arene (C4A)} and Calix[5]arene (C5A) in supersonic jets. By the measurements of UV-UV hole burning and IR-UV double resonance spectra, it was found that C4A has a single isomer with C symmetry, while C5A has at least two isomers; one isomer has C symmetry while the other isomer has the structure in which one of the phenol is inverted. The ability of the encapsulation has been studied by using rare gas, nitrogen, and methane as guest molecules. The electronic spectra suggest that the first guest molecule is encapsulated inside the cavity while the next molecules are bound outside
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
ENCAPSULATION OF WATER MOLECULES BY DIBENZO-18-CROWN-6-ETHER IN A SUPERSONIC JET
No full textR. Kusaka, Y. Inokuchi, and T. Ebata, Phys. Chem. Chem. Phys. 9, 4452 (2007).Author Institution: Department of Chemistry, Graduate School of Science, Hiroshima University, Higashi-Hiroshima, 739-8526, JapanUV and IR spectra of jet-cooled Dibenzo-18-crown-6-ether (DB18C6) and DB18C6-(HO) are observed by laser induced fluorescence (LIF), UV-UV hole-burning and IR-UV double resonance spectroscopy }. The LIF spectrum exhibited complicated vibronic structure in the region of 35500-36800 cm. The UV-UV hole-burning and IR-UV double resonance spectra suggest the existence of two conformers for DB18C6; one is "boat-type" structure having C symmetry, and the other is "chair-type" structure having C symmetry. For the hydrated clusters, we assigned most of them to the "boat-type" DB18C6-(HO). Details of the encapsulation structure in DB18C6-(HO) will be discussed by the comparison of the observed IR spectra with those obtained by quantum chemical calculation
Current Status on Cholangiocarcinoma and Gallbladder Cancer
No full textBACKGROUND: Cholangiocarcinomas (CC) as well as gallbladder cancers are relatively rare and intractable diseases. Clinical, pathological, and epidemiological studies on these tumors have been under investigation. The current status and/or topics on biliary tract cancers have been reported in the East West Association of Liver Tumor (EWALT), held in Milano, Italy in 2015.SUMMARY: All the authors, herein, specifcally reported the current status and leading-edge findings on biliary tract cancers as the following sequence: epidemiology of CC, surgical therapy for intrahepatic CC, surgical therapy for perihilar CC, surgical therapy for gallblad der cancer, chemotherapy for biliary tract cancers, and new histological features in CC.KEY MESSAGE: The present review article will update the knowledge on biliary tract cancers, en hancing the quality of daily clinical practice. However, many features about these cancers remain unknown; further studies are required to establish disease-specific optimal treatment strategies.</p
Handwritten biographical information on Paulina T. McClung Merritt
No full textA handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
No full textIFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Pelevin’s Trinity in the novel “t”: author – protagonist – reader
No full textThe article attempts to interpret Pelevin's artistic strategy in the novel "T" by exploring its subject organization and addressing the key problems of the author, the protagonist, and the reader as they are seen by the researcher. The article analyzes the peculiarities of constructing the narrative reality in the novel "T", and goes on to discuss Pelevin's philosophic models of the development of the humankind, and the emergence of his new anthropology
Measuring industry-science links through inventor-author relations: A profiling method
No full textIn this pilot study we examine the performance of text-based profiling in recovering a set of validated inventor-author links. In a first step we match patents and publications solely based on their similarity in content. Next, we compare inventor and author names on the highest ranked matches for the occurrence of name matches. Finally, we compare these candidate matches with the names listed in a validated set of inventor-author names. Our text-based profile methodology performs significantly better than a random matching of patents and publications, suggesting that text-based profiling is a valuable complementary tool to the name searches used in previous studies.innovation; industry-science links; text-based profiling;
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