1,355,635 research outputs found

    Ernesto Palacios. El derecho a la danza

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    Fil: Britos Musa, Mariana. Universidad Nacional de Villa María; Argentina..Fil: Engert, Valeria. Universidad Nacional de Villa María; Argentina..Fil: Granada, Marilyn. Universidad Nacional de Villa María; Argentina..Fil: Miranda, Adriana. Universidad Nacional de Villa María; Argentina.

    Engineering of cartilage tissue constructs in a 3-dimensional perfusion bioreactor culture system under controlled oxygen tension

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    The most relevant results generated in this thesis can be summarized as follow: · Adult human articular chondrocytes (AHAC) from elderly individuals expanded in culture medium supplemented with the growth factors TGFβ-1, FGF-2 and PDGF and subsequently cultured in 3-d pellets had an enhanced chondrogenic capacity when exposed to more physiological (i.e. 5%) oxygen levels. · In correlation with the enhanced tissue forming capacity of AHAC from elderly donors under low oxygen tension, the mRNA expression levels of selective matrix degrading enzymes were reduced as compared to conventional in vitro oxygen culture condition. · We developed an integrated bioreactor system, which streamlines within a single device the phases of perfusion cell seeding and prolonged perfusion culture of cell seeded scaffolds in vitro. · The culturing of uniformly seeded adult human articular chondrocytes under direct perfusion, where cells are continuously exposed to a normoxic range of oxygen levels, can maintain a uniform distribution of viable cells throughout thick porous scaffolds as compared to statically cultured constructs. · The culturing of constructs uniformly seeded with adult human articular chondrocytes under a more physiological range of oxygen resulted in a higher chondrogenic differentiation as compared to culture under normoxic levels. Anyhow, this effect was less pronounced as compared to statically cultured cell constructs or micromass cell pellets, possibly due to the flow induced shear forces. · Reduced perfusion flow rates applied to chondrocytes on porous scaffolds significantly induced more cartilaginous tissue in the presents of low vs. high oxygen levels. However the effects of low oxygen were not as marked as in pellet culture

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author, publisher and bookseller : a tripartite synergy in Nigerian book industry

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    This work is about the roles of Author, Publisher and Bookseller in Book development in Nigeria. The paper started by delving into the history of Book Publishing in Nigeria after which it proceeded by defining who an author, a publisher, and a bookseller is and expatiated on the indispensable roles of these key actors in Nigerian Book Industry and in the emerging Information Society. Furthermore, the various constraints to book development were identified while the paper advised on how the Book Industry can be further promoted in Nigeria. However, the paper concluded and made recommendations on how the Book sector can help in enhancing scholarship in the country
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